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Wernicke Korsakoff Syndrome

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Wernicke encephalopathy.

Tatsuya Fujikawa, Yuka Sogabe,

CMAJ (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne)
[2020, 192(6):E143]

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The image of memory: relationship between autobiographical memory and mental imagery in Korsakoff syndrome.

Frédérique Robin, Ahmed Moustafa, Mohamad El Haj,

We evaluated the relationship between autobiographical memory and mental imagery in Korsakoff syndrome (KS). We invited patients with KS and control participants to retrieve personal events and to perform measures of visual imagery (Taller/Wilder task), and spatial imagery (Clock Angles task). On the Taller/Wilder task, participants had to generate a ... Read more >>

Appl Neuropsychol Adult (Applied neuropsychology. Adult)
[2020, :1-7]

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[The 473rd case: renal failure, abdominal pain, and mental abnormality].

G Chen, L M Chen, X M Li,

A 43-year-old male presented with elevated serum creatinine for 4 years and developed abdominal pain for 3 days. He started peritoneal dialysis 2 months ago. Dialysis-related peritonitis was ruled out and acute gastroenteritis was diagnosed. The patient was administrated with ertapenem 500 mg/d. An acute mental abnormality developed 3 days ... Read more >>

Zhonghua Nei Ke Za Zhi (Zhonghua nei ke za zhi)
[2020, 59(1):82-85]

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Sex Differences in Korsakoff's Syndrome for Inhibition but Not for Episodic Memory or Flexibility.

Mohamad El Haj, Roy P C Kessels, Jean-Louis Nandrino,

BACKGROUND AND OBJECTIVES:While sex differences in cognitive abilities have been extensively studied in healthy populations, little is known about these differences in patients with Korsakoff syndrome (KS). METHODS:We investigated sex differences in verbal episodic memory, inhibition, and flexibility in 25 patients with KS and 25 control participants. RESULTS:The analysis demonstrated ... Read more >>

Am J Addict (The American journal on addictions)
[2020, 29(2):129-133]

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Acute amnestic syndromes.

Lucas Alessandro, Mario Ricciardi, Hernán Chaves, Ricardo F Allegri,

Acute amnestic syndromes are usually rare clinical events occurring in emergency situations. Etiological diagnosis can be challenging and underlying causes diverse. They can be transient and totally reversible, or accompanied by other neurological symptoms resulting in serious and irreversible brain damage. Pathophysiology of these syndromes mainly corresponds to structural or ... Read more >>

J. Neurol. Sci. (Journal of the neurological sciences)
[2020, 413:116781]

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The relationship between executive dysfunction and neuropsychiatric symptoms in patients with Korsakoff's syndrome.

Wiltine G Moerman-van den Brink, Loes van Aken, Els M L Verschuur, Serge J W Walvoort, Yvonne C M Rensen, Jos I M Egger, Roy P C Kessels,

Objective: Patients with Korsakoff's syndrome (KS) show executive dysfunction and neuropsychiatric symptoms. This study investigates whether specific executive subcomponents (shifting, updating, and inhibition) predict variance in neuropsychiatric symptoms. We hypothesized that shifting deficits, in particular, are associated with neuropsychiatric symptoms.Method: Forty-seven patients participated (mean age 61.5; 11 women). Executive function ... Read more >>

Clin Neuropsychol (The Clinical neuropsychologist)
[2020, :1-15]

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Atrophic mammillary bodies with hypointensities on susceptibility-weighted images: A case-study in Korsakoff syndrome.

Toshimasa Ikeda, Keita Sakurai, Noriyuki Matsukawa, Mari Yoshida,

J. Neurol. Sci. (Journal of the neurological sciences)
[2020, 408:116551]

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Thiamine (vitamin B1) in septic shock: a targeted therapy.

Ari Moskowitz, Michael W Donnino,

Thiamine (vitamin B1) is a water-soluble vitamin essential for human health. Thiamine deficiency is causal and/or contributory in a number of debilitating diseases including beri-beri, the Wernicke-Korsakoff syndrome, optic neuropathy, and others. While thiamine deficiency is relatively rare in developed nations as a result of dietary supplementation, thiamine deficiency is ... Read more >>

J Thorac Dis (Journal of thoracic disease)
[2020, 12(Suppl 1):S78-S83]

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Visual working memory capacity in Korsakoff's amnesia.

Erik Oudman, Martijn J Schut, Antonia F Ten Brink, Albert Postma, Stefan Van der Stigchel,

Introduction: Despite the interest in memory functioning in Korsakoff's syndrome (KS), visual working memory capacity in KS is still poorly understood. Results from the last decades on working memory limitations in KS appear to be mixed, clearly calling for further investigations.Method: We investigated visual working memory storage capacity of patients diagnosed ... Read more >>

J Clin Exp Neuropsychol (Journal of clinical and experimental neuropsychology)
[2020, :1-8]

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Alcohol and Dementia - What is the Link? A Systematic Review.

Caspar Wiegmann, Inge Mick, Eva J Brandl, Andreas Heinz, Stefan Gutwinski,

Background:Dementia is a globally increasing health issue and since no cure is currently available, prevention is crucial. The consumption of alcohol is a controversially discussed risk factor for dementia. While many previously published epidemiological studies reported a risk reduction by light to moderate alcohol consumption, there is no persuasive model ... Read more >>

Neuropsychiatr Dis Treat (Neuropsychiatric Disease and Treatment)
[2020, 16:87-99]

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A view from the acute hospital: managing patients with alcohol problems.

David Pang, Pete Duffield, Ed Day,

Regular heavy consumption of alcohol is associated with a wide range of physical, psychological and social problems. All health-care clinicians should be able to screen for and detect problematic levels of alcohol consumption in their patients, and deliver an effective brief intervention. When patients with alcohol dependence are admitted to ... Read more >>

Br J Hosp Med (Lond) (British journal of hospital medicine (London, England : 2005))
[2019, 80(9):500-506]

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Health problems and care needs in patients with Korsakoff's syndrome: A systematic review.

Mirjam Johanna van Dam, Berno van Meijel, Albert Postma, Erik Oudman,

WHAT IS KNOWN ON THE SUBJECT?: Patients with Korsakoff's syndrome suffer from a broad range of comorbid somatic and/or psychiatric conditions. The various health problems in patients with Korsakoff's syndrome limit their ability to perform daily activities and also negatively affect their social functioning. WHAT THE PAPER ADDS TO EXISTING ... Read more >>

J Psychiatr Ment Health Nurs (Journal of psychiatric and mental health nursing)
[2019, :]

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Wernicke-Korsakoff Syndrome in a Patient With Celiac Disease and Obsessive-Compulsive Disorder: A Case Report.

Malya Sahu, Marissa Beal, Keira Chism, Madeleine A Becker,

Psychosomatics (Psychosomatics)
[2019, :]

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Recent Advances in the Treatment of Cerebellar Disorders.

Hiroshi Mitoma, Mario Manto, Jordi Gandini,

Various etiopathologies affect the cerebellum, resulting in the development of cerebellar ataxias (CAs), a heterogeneous group of disorders characterized clinically by movement incoordination, affective dysregulation, and cognitive dysmetria. Recent progress in clinical and basic research has opened the door of the ''era of therapy" of CAs. The therapeutic rationale of ... Read more >>

Brain Sci (Brain sciences)
[2019, 10(1):]

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A patient with Korsakoff syndrome of psychiatric and alcoholic etiology presenting as DSM-5 mild neurocognitive disorder [Corrigendum].

Neuropsychiatr Dis Treat (Neuropsychiatric Disease and Treatment)
[2019, 15:1895]

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Wernicke encephalopathy following gastrojejunostomy: A case report and review of the literature.

Leila Alizadeh, Zahra Mostafavi, Amirreza Jahanshahi, Mehdi Khani, Masoud Nouri-Vaskeh,

Introduction:Non-alcoholic Wernicke encephalopathy (WE) is a life-threatening condition, which is caused due to thiamine deficiency. We reported a case of non-alcoholic WE following gastrojejunostomy. Case presentation:A 31-year-old woman was admitted to our tertiary care center complaining about intractable nausea and vomiting following her gastrojejunostomy. She had undergone gastrojejunostomy because of ... Read more >>

Turk J Emerg Med (Turkish journal of emergency medicine)
[2019, 19(4):154-156]

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Alcohol Induced Wernicke Encephalopathy with Atypical MRI Findings.

Devansh Pandey, James L Kuhn, Hilda Tejero, James S Banks,

Wernicke encephalopathy is a neurological complication of thiamine deficiency, usually in the setting of poor diet, classically with alcoholism. Patients present with acute onset of encephalopathy, oculomotor dysfunction, gait ataxia and memory impairment. If untreated, the disorder can result in severe morbidity and possibly death; patient outcomes are entirely dependent ... Read more >>

Cureus (Cureus)
[2019, 11(7):e5203]

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Brain 18FDG-PET pattern in patients with alcohol-related cognitive impairment.

Virgile Clergue-Duval, Frank Questel, Julien Azuar, Claire Paquet, Emmanuel Cognat, Jihed Amami, Mathieu Queneau, Alexandra Dereux, Thomas Barré, Frank Bellivier, Karim Farid, Florence Vorspan,

PURPOSE:Brain positron emission tomography using 18F-fluorodeoxyglucose (18FDG-PET) provides a metabolic assessment of brain function that is useful for differential diagnosis among several neurodegenerative diseases manifested by cognitive impairment (CI). The purpose of the study is to describe the pattern of 18FDG-PET abnormalities in patients with CI related to alcohol use ... Read more >>

Eur. J. Nucl. Med. Mol. Imaging (European journal of nuclear medicine and molecular imaging)
[2020, 47(2):281-291]

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Prevalence and Improvement of Caine-Positive Wernicke-Korsakoff Syndrome in Psychiatric Inpatient Admissions.

Shihong Lin, Idris E Leppla, Haijuan Yan, Julia M Probert, Privia A Randhawa, Jeannie-Marie S Leoutsakos, John C Probasco, Karin J Neufeld,

BACKGROUND:Wernicke-Korsakoff Syndrome (WKS) resulting from thiamine deficiency is classically defined as including encephalopathy, ataxia, and ophthalmoplegia. Only 16% of autopsy-confirmed patients with WKS exhibit all three signs. Caine-positive WKS criteria include two or more of the following: nutritional deficiency, delirium or mild memory impairment, cerebellar dysfunction/ataxia, and oculomotor abnormalities. OBJECTIVE:We ... Read more >>

Psychosomatics (Psychosomatics)
[2020, 61(1):31-38]

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Nonalcoholic Wernicke's encephalopathy: a retrospective study of 17 cases.

Hongzhen Yin, Qiancheng Xu, Yingya Cao, Yupeng Qi, Tao Yu, Weihua Lu,

J. Int. Med. Res. (The Journal of international medical research)
[2019, 47(10):4886-4894]

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Hyperemesis gravidarum causing Wernicke-Korsakoff syndrome: A rare complication.

Vineet V Mishra, Ruchika A Verneker,

Wernicke-Korsakoff syndrome (WKS) is a rare neurological disorder due to severe thiamine deficiency. It is most prevalent among alcoholics. However in nonalcoholics the prevalence varies from 0.04% to 0.13%. We report a case of WKS due to hyperemesis gravidarum. Primigravida patient with 16 weeks pregnancy with continuous vomiting for 1 month ... Read more >>

J. Obstet. Gynaecol. Res. (The journal of obstetrics and gynaecology research)
[2019, 45(9):1929-1931]

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Future Thinking in Korsakoff Syndrome.

Mohamad El Haj, Ahmed A Moustafa, Jean-Louis Nandrino,

AIMS:Prior research has been mainly concerned with the ability of patients with Korsakoff syndrome (KS) to project themselves into the past. Little is known about the patients' ability to project themselves into the future. We therefore compared past and future thinking in patients with KS. METHODS:We invited patients with KS ... Read more >>

Alcohol Alcohol. (Alcohol and alcoholism (Oxford, Oxfordshire))
[2019, 54(4):455-462]

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Wernicke Encephalopathy-Clinical Pearls.

Shirshendu Sinha, Archish Kataria, Bhanu Prakash Kolla, Nuria Thusius, Larissa L Loukianova,

Wernicke encephalopathy (WE) was first described by Carl Wernicke in 1881. WE is caused by thiamine deficiency. Alcoholism is the most common etiologic factor associated with WE in the United States, but it can occur in any patient with a nutritional deficiency state such as hyperemesis gravidarum, intestinal obstruction, and ... Read more >>

Mayo Clin. Proc. (Mayo Clinic proceedings)
[2019, 94(6):1065-1072]

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Canadian Guidelines on Alcohol Use Disorder Among Older Adults.

Peter R. Butt, Marilyn White-Campbell, Sarah Canham, Ann Dowsett Johnston, Eunice O. Indome, Bonnie Purcell, Jennifer Tung, Lisa Van Bussel,

BackgroundAlcohol use disorder (AUD) is an increasingly common, under-recognized, and under-treated health concern in older adults. Its prevalence is expected to reach unprecedented levels as the Canadian population ages. In response, Health Canada commissioned the Canadian Coalition of Seniors’ Mental Health to create guidelines for the prevention, screening, assessment, and ... Read more >>

Can Geriatr J (Canadian Geriatrics Journal)
[2020, 23(1):143-148]

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Signal Change in the Mammillary Bodies after Perinatal Asphyxia.

M Molavi, S D Vann, L S de Vries, F Groenendaal, M Lequin,

BACKGROUND AND PURPOSE:Research into memory deficits associated with hypoxic-ischemic encephalopathy has typically focused on the hippocampus, but there is emerging evidence that the medial diencephalon may also be compromised. We hypothesized that mammillary body damage occurs in perinatal asphyxia, potentially resulting in mammillary body atrophy and subsequent memory impairment. MATERIALS ... Read more >>

AJNR Am J Neuroradiol (AJNR. American journal of neuroradiology)
[2019, 40(11):1829-1834]

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