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Wernicke Encephalopathy

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Non-alcoholic beriberi, Wernicke encephalopathy and long-term eating disorder: case report and a mini-review.

Vittorio Mantero, Nicola Rifino, Gisella Costantino, Andrea Farina, Ugo Pozzetti, Monica Sciacco, Michela Ripolone, Graziella Bianchi, Andrea Salmaggi, Andrea Rigamonti,

INTRODUCTION:Nowadays, reports of beriberi are rare in developed countries. Wernicke encephalopathy may be present in about 25% of patients with beriberi. CASE REPORT:We report the case of a woman with history of depression and chronic eating disorder, who complained Wernicke encephalopathy and beriberi. Sural nerve and muscular biopsy were performed, ... Read more >>

Eat Weight Disord (Eating and weight disorders : EWD)
[2020, :]

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Wernicke encephalopathy-a rare complication of hyperemesis gravidarum.

Miroslav Žigrai, Viera Smetanová, Karin Gmitterová, Petra Klepancová, Milan Vyskočil,

We report a rare case of Wernicke encephalopathy (WE) in a 35-year-old woman with hyperemesis gravidarum (HG). Initially, the disease manifested as passivity, a loss of interest, sleeping too much, apathy and disorientation. The correct diagnosis was established after the detection of typical pathological findings of WE in the thalamus ... Read more >>

Eur J Clin Nutr (European journal of clinical nutrition)
[2020, :]

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Wernicke encephalopathy.

Tatsuya Fujikawa, Yuka Sogabe,

CMAJ (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne)
[2020, 192(6):E143]

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Chemokine CXCL13 in serum, CSF and blood-CSF barrier function: evidence of compartment restriction.

Georg Pilz, Irma Sakic, Peter Wipfler, Jörg Kraus, Elisabeth Haschke-Becher, Wolfgang Hitzl, Eugen Trinka, Andrea Harrer,

BACKGROUND AND PURPOSE:Elevation of the chemokine CXCL13 in CSF frequently occurs during active and acute CNS inflammatory processes and presumably is associated with B cell-related immune activation. Elevation levels, however, vary a lot and "leaking" of CXCL13 from blood across dysfunctional brain barriers is a possible source. The aim was ... Read more >>

Fluids Barriers CNS (Fluids and barriers of the CNS)
[2020, 17(1):7]

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Hypercalcemic Encephalopathy as an Initial Presentation of Multiple Myeloma.

Durga Shankar Meena, Gopal Krishana Bohra, Mahendra Kumar Garg, Abhishek Purohit, Deepak Kumar, Swapnil Tripathi,

We report the case of an 84-year-old female presented to us with acute onset altered sensorium. On investigation, neurological and infectious causes were ruled out. On further evaluation, her serum calcium was found elevated (15.07 gm/dl). The diagnosis of hypercalcemic encephalopathy was made with the possibility of multiple myeloma due to ... Read more >>

Case Rep Emerg Med (Case Reports in Emergency Medicine)
[2020, 2020:4746865]

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[The 473rd case: renal failure, abdominal pain, and mental abnormality].

G Chen, L M Chen, X M Li,

A 43-year-old male presented with elevated serum creatinine for 4 years and developed abdominal pain for 3 days. He started peritoneal dialysis 2 months ago. Dialysis-related peritonitis was ruled out and acute gastroenteritis was diagnosed. The patient was administrated with ertapenem 500 mg/d. An acute mental abnormality developed 3 days ... Read more >>

Zhonghua Nei Ke Za Zhi (Zhonghua nei ke za zhi)
[2020, 59(1):82-85]

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Wernicke encephalopathy associated with hyperemesis gravidarum.

William J Meggs, Samuel K Lee, Jennifer N Parker-Cote,

Emergency physicians frequently treat hyperemesis gravidarum and should be aware of possible complications. Wernicke encephalopathy secondary to thiamine deficiency should be considered in the differential diagnosis of acute encephalopathy in pregnant women. A seventeen-week pregnant 27-year-old woman presented to the Emergency Department with nausea, emesis, and right upper quadrant abdominal ... Read more >>

Am J Emerg Med (The American journal of emergency medicine)
[2019, :]

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MELAS Missed for Years: Stroke-Like Lesions Are No Indication for Brain Biopsy.

J Finsterer,

A 56-year-old female with a history of chronic alcoholism until age 38 y with a relapse between ages 45 and 46 y developed seizures, psychosis, and hemianopia to the left at age 46 y. Imaging revealed a right parieto-occipital lesion with intralesional bleeding. Five months after the first lesion she developed a second ... Read more >>

Case Rep Neurol Med (Case reports in neurological medicine)
[2019, 2019:9312451]

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Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge.

Lauren Halavonich, Sophie Robert, Dan McGraw, Erin Weeda, Kristen Mullinax, Bailey Bass,

Introduction:Delirium is an acute, fluctuating change in mental status, often associated with behavioral manifestations such as agitation. Literature suggests that many patients who continue on antipsychotics for extended management of delirium are not provided instructions for discontinuation. However, there is a positive correlation between consult services and instructions for discontinuation. ... Read more >>

Ment Health Clin (The mental health clinician)
[2020, 10(1):25-29]

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Atrophic mammillary bodies with hypointensities on susceptibility-weighted images: A case-study in Korsakoff syndrome.

Toshimasa Ikeda, Keita Sakurai, Noriyuki Matsukawa, Mari Yoshida,

J. Neurol. Sci. (Journal of the neurological sciences)
[2020, 408:116551]

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CLINICAL PRACTICE GUIDELINES FOR THE PERIOPERATIVE NUTRITION, METABOLIC, AND NONSURGICAL SUPPORT OF PATIENTS UNDERGOING BARIATRIC PROCEDURES - 2019 UPDATE: COSPONSORED BY AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY, THE OBESITY SOCIETY, AMERICAN SOCIETY FOR METABOLIC & BARIATRIC SURGERY, OBESITY MEDICINE ASSOCIATION, AND AMERICAN SOCIETY OF ANESTHESIOLOGISTS - EXECUTIVE SUMMARY.

Jeffrey I Mechanick, Caroline Apovian, Stacy Brethauer, W Timothy Garvey, Aaron M Joffe, Julie Kim, Robert F Kushner, Richard Lindquist, Rachel Pessah-Pollack, Jennifer Seger, Richard D Urman, Stephanie Adams, John B Cleek, Riccardo Correa, M Kathleen Figaro, Karen Flanders, Jayleen Grams, Daniel L Hurley, Shanu Kothari, Michael V Seger, Christopher D Still,

Objective: The development of these updated clinical practice guidelines (CPGs) was commissioned by the American Association of Clinical Endocrinologists (AACE), The Obesity Society, American Society of Metabolic and Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists Boards of Directors in adherence with the AACE 2017 protocol for standardized ... Read more >>

Endocr Pract (Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists)
[2019, 25(12):1346-1359]

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Confusion vs Broca Aphasia: A Case Report.

Regina Wang, Christi Wiley,

INTRODUCTION:Broca aphasia presents with impaired expression of spoken and/or written language and is often caused by infarction in the Broca area in the frontal lobe. We present a case of Broca aphasia that was initially interpreted as confusion. CASE PRESENTATION:A 76-year-old woman was brought to the Emergency Department because of ... Read more >>

Perm J (The Permanente journal)
[2020, 24:]

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A Rare Cause of Optic Neuropathy.

Isabel O Cruz, Sara Alves Pereira, Bruna Vieira, Inês Chora, Paulo Coelho,

Lyme disease is a multisystem infection caused by Borrelia burgdorferi that mainly affects the joints, the heart, and the nervous system. Neurological complications usually manifest in untreated patients and present as meningitis, cranial neuropathies, and radiculoneuritis. The authors present the case of a 48-year-old male who developed loss of vision ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6906]

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Subclinical thiamine deficiency identified by preoperative evaluation in an ovarian cancer patient: Diagnosis and the need for preoperative thiamine measurement.

Hideki Onishi, Mayumi Ishida, Nozomu Uchida, Daisuke Shintani, Tadaaki Nishikawa, Kosei Hasegawa, Keiichi Fujiwara, Tatsuo Akechi,

OBJECTIVE:Although thiamine deficiency (TD) and Wernicke encephalopathy (WE) are not rare in cancer patients, the cases reported to date developed TD and/or WE after treatment had started. METHOD:From a series of cancer patients, we report a patient diagnosed with TD without the typical clinical symptoms of WE at the preoperative ... Read more >>

Palliat Support Care (Palliative & supportive care)
[2019, 17(5):609-610]

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A Case of Ascending Sensory Neuropathy Due to Acute Onset Thiamine Deficiency After Intragastric Balloon Placement.

Sheetal Patel, Victoria Gómez,

Endoscopic bariatric therapies (EBTs) are emerging as nonsurgical weight loss interventions that are being used with increasing frequency. Similar to the potential for early and late complications from bariatric surgeries, metabolic derangements and nutritional deficiencies can also be seen after EBTs. In particular, thiamine deficiency is a well-known complication typically ... Read more >>

Obes Surg (Obesity surgery)
[2019, 29(10):3404-3405]

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Functional neurological symptoms masquerading as Wernicke encephalopathy following bariatric surgery.

Andrew M Kiselica, Sabra Rosen, Jared F Benge,

Wernicke encephalopathy (WE), caused by thiamine deficiency, is classically associated with alcoholism but is increasingly recognized among patients who have undergone bariatric surgery. As with other neurocognitive conditions, alternative explanations for symptoms, such as psychiatric, neurological, and motivational factors, must be considered before arriving at a diagnosis of WE. We ... Read more >>

Proc (Bayl Univ Med Cent) (Proceedings (Baylor University. Medical Center))
[2019, 32(4):607-609]

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Thiamine Deficiency in a Child with Short Bowel Syndrome and Review.

Ioannis Roilides, Konstantina Vasilaki, Ioannis Xinias, Elias Iosifidis, Charalampos Antachopoulos, Emmanuel Roilides,

Thiamine (vitamin B1) is a water-soluble vitamin that is not endogenously synthesized in humans. It is absorbed by the small intestine, where it is activated. Its active form acts as a coenzyme in many energy pathways. We report a rare case of thiamine deficiency in a 3.5-year old boy with ... Read more >>

Pediatr Gastroenterol Hepatol Nutr (Pediatric gastroenterology, hepatology & nutrition)
[2019, 22(5):493-499]

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Rapid same-day resolution of internuclear ophthalmoplegia in Wernicke encephalopathy following parenteral high dose thiamine.

Jacob Winters, Eric Niespodzany, T Ashwini Kini, Bayan Al Othman, Andrew G Lee,

Can. J. Ophthalmol. (Canadian journal of ophthalmology. Journal canadien d'ophtalmologie)
[2019, :]

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Acute necrotizing encephalopathy in an adult as a complication of H1N1 infection.

Heba S Abdelrahman, Ahmed M Safwat, Mahmoud M Alsagheir,

Acute necrotizing encephalitis is one of the recognized influenza-associated encephalopathies which has a characteristic multifocal symmetric involvement of the thalami bilaterally with only very few cases were reported in adults. We present a case of a young adult female who was presented with post-H1N1 Acute Necrotizing Encephalopathy with full neurological ... Read more >>

BJR Case Rep (BJR case reports)
[2019, 5(4):20190028]

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A Review of Obstetrical Outcomes and Complications in Pregnant Women after Bariatric Surgery.

Yasmeen A Haseeb,

Bariatric surgery (BS) is a novel treatment for weight reduction with longer lasting health benefits. This review aimed to summarise the available evidence regarding the fetomaternal outcomes and the most common challenges and complications in pregnancies following BS. Google Scholar (Google LLC, Mountain View, California, USA) and PubMed® (National Library ... Read more >>

Sultan Qaboos Univ Med J (Sultan Qaboos University medical journal)
[2019, 19(4):e284-e290]

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Nausea and vomiting of pregnancy and hyperemesis gravidarum.

Marlena S Fejzo, Jone Trovik, Iris J Grooten, Kannan Sridharan, Tessa J Roseboom, Åse Vikanes, Rebecca C Painter, Patrick M Mullin,

Nausea and vomiting of pregnancy (NVP) is a common condition that affects as many as 70% of pregnant women. Although no consensus definition is available for hyperemesis gravidarum (HG), it is typically viewed as the severe form of NVP and has been reported to occur in 0.3-10.8% of pregnant women. ... Read more >>

Nat Rev Dis Primers (Nature reviews. Disease primers)
[2019, 5(1):62]

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Deciphering the factors that influence participation in studies requiring serial lumbar punctures.

Gregory S Day, Tracy Rappai, Sushila Sathyan, John C Morris,

Introduction:Cerebrospinal fluid biomarkers increasingly inform the causes of dementia and may provide objective markers of disease progression. There is a need to decipher participant and procedural factors that promote participation in studies incorporating longitudinal biomarker measures. Methods:Participant and procedural factors associated with participation in longitudinal biomarker studies were determined in ... Read more >>

Alzheimers Dement (Amst) (Alzheimer's & dementia (Amsterdam, Netherlands))
[2020, 12(1):e12003]

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Metronidazole-induced Encephalopathy.

Htay Phyu, Michael B Edmond, Takaaki Kobayashi,

Metronidazole is commonly used in the treatment of anaerobic infections. While neuropathy is known to be associated with metronidazole, encephalopathy has been rarely reported. We herein present a case of metronidazole-induced encephalopathy presenting as frequent falls and slurred speech. Magnetic resonance imaging of the brain demonstrated T2/FLAIR hyperintensity in the ... Read more >>

IDCases (IDCases)
[2019, 18:e00639]

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Wernicke encephalopathy following gastrojejunostomy: A case report and review of the literature.

Leila Alizadeh, Zahra Mostafavi, Amirreza Jahanshahi, Mehdi Khani, Masoud Nouri-Vaskeh,

Introduction:Non-alcoholic Wernicke encephalopathy (WE) is a life-threatening condition, which is caused due to thiamine deficiency. We reported a case of non-alcoholic WE following gastrojejunostomy. Case presentation:A 31-year-old woman was admitted to our tertiary care center complaining about intractable nausea and vomiting following her gastrojejunostomy. She had undergone gastrojejunostomy because of ... Read more >>

Turk J Emerg Med (Turkish journal of emergency medicine)
[2019, 19(4):154-156]

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Vision Loss As a Presenting Feature of Wernicke Encephalopathy.

Amol A Sura, Joel K Cure, Lanning B Kline,

J Neuroophthalmol (Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society)
[2019, 39(3):380-382]

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