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Caenorhabditis Intervention Testing Program: the creatine analog β-guanidinopropionic acid does not extend lifespan in nematodes.

Anna L Coleman-Hulbert, Erik Johnson, Christine A Sedore, Stephen A Banse, Max Guo, Monica Driscoll, Gordon J Lithgow, Patrick C Phillips,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 3 times

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Identification of four Drosophila Toll-related proteins as ligands for the PTP69D receptor tyrosine phosphatase.

Namrata Bali, Hyung-Kook Lee, Kai Zinn,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

Cited: 1 time

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Small scale adeno-associated virus-vector production for preclinical gene delivery based on chloroform precipitation.

Marcus Davidsson, Andreas Heuer,

Neural Regen Res (Neural regeneration research)
[2022, 17(1):99-100]

Cited: 0 times

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Blood virosphere in febrile Tanzanian children.

Samuel Cordey, Florian Laubscher, Mary-Anne Hartley, Thomas Junier, Kristina Keitel, Mylène Docquier, Nicolas Guex, Christian Iseli, Gael Vieille, Philippe Le Mercier, Anne Gleizes, Josephine Samaka, Tarsis Mlaganile, Frank Kagoro, John Masimba, Zamzam Said, Hosiana Temba, Gasser H Elbanna, Caroline Tapparel, Marie-Celine Zanella, Ioannis Xenarios, Jacques Fellay, Valérie D'Acremont, Laurent Kaiser,

Viral infections are the leading cause of childhood acute febrile illnesses motivating consultation in sub-Saharan Africa. The majority of causal viruses are never identified in low-resource clinical settings as such testing is either not part of routine screening or available diagnostic tools have limited ability to detect new/unexpected viral variants. ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):982-993]

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Discussing reproductive goals with healthcare providers among women living with HIV in Canada: the role of provider gender and patient comfort.

Lashanda Skerritt, Alexandra de Pokomandy, Nadia O'Brien, Nadia Sourial, Ann N Burchell, Gillian Bartlett, Tibor Schuster, Danielle Rouleau, Karène Proulx-Boucher, Neora Pick, Deborah Money, Rebecca Gormley, Allison Carter, Mark H Yudin, Mona Loutfy, Angela Kaida, ,

Antiretroviral therapy effectively prevents sexual and vertical transmission of HIV. Yet, some women living with HIV report having unmet needs for reproductive health care. This study measured the prevalence of women discussing reproductive goals with any current healthcare provider and assessed the effect of the current HIV care provider's gender ... Read more >>

Sex Reprod Health Matters (Sexual and reproductive health matters)
[2021, 29(1):1932702]

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Pan-coronavirus fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and simian immunodeficiency virus.

Danwei Yu, Yuanmei Zhu, Hongxia Yan, Tong Wu, Huihui Chong, Yuxian He,

EK1 peptide is a membrane fusion inhibitor with broad-spectrum activity against human coronaviruses (CoVs). In the outbreak of COVID-19, we generated a lipopeptide EK1V1 by modifying EK1 with cholesterol, which exhibited significantly improved antiviral activity. In this study, we surprisingly found that EK1V1 also displayed potent cross-inhibitory activities against divergent ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):810-821]

Cited: 1 time

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Comparative pathogenicity and environmental transmission of recent highly pathogenic avian influenza H5 viruses.

Nancy Beerens, Evelien A Germeraad, Sandra Venema, Eline Verheij, Sylvia B E Pritz-Verschuren, Jose L Gonzales,

Strategies to control spread of highly pathogenic avian influenza (HPAI) viruses by wild birds appear limited, hence timely characterization of novel viruses is important to mitigate the risk for the poultry sector and human health. In this study we characterize three recent H5-clade 2.3.4.4 viruses, the H5N8-2014 group A virus ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):97-108]

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Epidemiological profile and molecular genetic characterization of HIV-1 among female sex workers and elderly male clients in Guangxi, China.

Xiu Chen, Chunwei Qin, Rongfeng Chen, Yunxuan Huang, Yuexiang Xu, Qiao Tang, Xianjun Liang, Bing Peng, Yi Shao, Yao Yang, Jie Chen, Xinwei Wang, Liufang Wen, Bingyu Liang, Li Ye, Xionglin Qin, Junjun Jiang, Hao Liang,

The HIV/AIDS prevalence in female sex workers (FSWs) and elderly male clients is increasing in Guangxi, China, but the transmission relationship between them remains unclear. This study aims to illuminate the transmission network between FSWs and elderly male clients using molecular epidemiological analyses. Phylogenetic analysis indicated that CRF01_AE was the ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):384-395]

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Identification of key residues involved in the neuraminidase antigenic variation of H9N2 influenza virus.

Fei Wang, Jinsen Wu, Yajuan Wang, Zhimin Wan, Hongxia Shao, Kun Qian, Jianqiang Ye, Aijian Qin,

Influenza A H9N2 virus causes economic loss to the poultry industry and has likely contributed to the genesis of H5N1 and H7N9 viruses. The neuraminidase (NA) of H9N2 virus, like haemagglutinin, is under antibody selective pressure and may undergo antigenic change; however, its antigenic structure remains to be elucidated. In ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):210-219]

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PB1 S524G mutation of wild bird-origin H3N8 influenza A virus enhances virulence and fitness for transmission in mammals.

Xinghai Zhang, Yuanguo Li, Song Jin, Yiming Zhang, Leiyun Sun, Xinyu Hu, Menglin Zhao, Fangxu Li, Tiecheng Wang, Weiyang Sun, Na Feng, Hongmei Wang, Hongbin He, Yongkun Zhao, Songtao Yang, Xianzhu Xia, Yuwei Gao,

Influenza H3N8 viruses have been recovered frequently from wild bird species, including Anseriformes (primarily from migratory ducks) and Charadriiformes (primarily from shorebirds). However, little attention has been given to the transmission ability of H3N8 avian influenza viruses among mammals. Here, we study the potential human health threat and the molecular ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1038-1051]

Cited: 0 times

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Attenuation of porcine deltacoronavirus disease severity by porcine reproductive and respiratory syndrome virus coinfection in a weaning pig model.

Xinrong Zhou, Xinna Ge, Yongning Zhang, Jun Han, Xin Guo, Yanhong Chen, Lei Zhou, Hanchun Yang,

Porcine deltacoronavirus (PDCoV) is a potentially emerging zoonotic pathogen that causes severe diarrhea in young pigs, with a risk of fatal dehydration. Its pathogenicity on neonatal piglet has been previously reported, however, it is less known if the coinfection with immunosuppressive pathogens can influence PDCoV disease manifestation. Here, a coinfection ... Read more >>

Virulence (Virulence)
[2021, 12(1):1011-1021]

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Bacterial and viral infections and related inflammatory responses in chronic obstructive pulmonary disease.

Silvestro Ennio D'Anna, Mauro Maniscalco, Francesco Cappello, Mauro Carone, Andrea Motta, Bruno Balbi, Fabio L M Ricciardolo, Gaetano Caramori, Antonino Di Stefano,

In chronic obstructive pulmonary disease (COPD) patients, bacterial and viral infections play a relevant role in worsening lung function and, therefore, favour disease progression. The inflammatory response to lung infections may become a specific indication of the bacterial and viral infections. We here review data on the bacterial-viral infections and ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):135-150]

Cited: 1 time

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Knowledge, attitudes and prevention practices regarding HIV/AIDS among barbers in Ho municipality, Ghana.

Mercy Demaris Quarm, Jacqueline Mthembu, Khangelani Zuma, Elvis Enowbeyang Tarkang,

The barbing industry poses particular public health risks if it is not conducted in a safe and hygienic manner. These risks can lead to the transmission of infectious diseases like the Human Immunodeficiency Virus (HIV) to the barbers or their clients. This study investigated the knowledge, attitudes and prevention practices ... Read more >>

SAHARA J (SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance)
[2021, 18(1):42-51]

Cited: 0 times

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HIV/AIDS treatment funding system to support the people affected by HIV/AIDS in Surakarta, Indonesia.

Argyo Demartoto, Bhisma Murti, Siti Zunariyah,

People Living with HIV/AIDS (PLWHA's) quality of life (QoL) is determined by the lifetime treatment sustainability. Republic of Indonesia Minister of Health's Decree Number 328 of 2003 stated that government subsidies the PLWHA's medication and treatment, despite not covering entire medication and treatment cost. The objective of research was to ... Read more >>

SAHARA J (SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance)
[2021, 18(1):1-16]

Cited: 1 time

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Traditional healers as client advocates in the HIV-endemic region of Maputo, Mozambique: results from a qualitative study.

Radhika Sundararajan, Patricio V Langa, Trisha Morshed, Sandra Manuel,

Traditional healers are commonly utilised throughout sub-Saharan Africa instead of - and in concert with - biomedical facilities. Traditional healers are trusted providers and prominent community members and could be important partners in improving engagement with HIV services in endemic contexts. Our study sought to understand the roles of healers ... Read more >>

SAHARA J (SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance)
[2021, 18(1):77-85]

Cited: 0 times

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Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice.

Milan Kuchař, Petr Kosztyu, Veronika Daniel Lišková, Jiří Černý, Hana Petroková, Eliška Vróblová, Michal Malý, Lucie Vaňková, Michal Křupka, Leona Rašková Kafková, Pavlína Turánek Knotigová, Jarmila Dušková, Jan Dohnálek, Josef Mašek, Jaroslav Turánek, Milan Raška, Petr Malý,

One of the proposed strategies for the development of a more efficient HIV-1 vaccine is based on the identification of proteins binding to a paratope of chosen broadly neutralizing antibody (bNAb) that will mimic cognate HIV-1 Env (glyco)protein epitope and could be used as potent immunogens for induction of protective ... Read more >>

Virulence (Virulence)
[2021, 12(1):1271-1287]

Cited: 0 times

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High dose of vesicular stomatitis virus-vectored Ebola virus vaccine causes vesicular disease in swine without horizontal transmission.

Igor Morozov, Thomas P Monath, David A Meekins, Jessie D Trujillo, Sun-Young Sunwoo, Kinga Urbaniak, In Joong Kim, Sanjeev K Narayanan, Sabarish V Indran, Wenjun Ma, William C Wilson, Cassandra O'Connor, Sheri Dubey, Sean P Troth, Beth-Ann Coller, Richard Nichols, Brian K Martin, Heinz Feldmann, Juergen A Richt,

<b>ABSTRACT</b>The recent impact of Ebola virus disease (EVD) on public health in Africa clearly demonstrates the need for a safe and efficacious vaccine to control outbreaks and mitigate its threat to global health. ERVEBO® is an effective recombinant Vesicular Stomatitis Virus (VSV)-vectored Ebola virus vaccine (VSV-EBOV) that was approved by ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):651-663]

Cited: 0 times

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'If you are found taking medicine, you will be called names and considered less of a man': young men's engagement with HIV treatment and care during ulwaluko (traditional initiation and circumcision) in the Eastern Cape Province of South Africa.

L Gittings, R Hodes, C Colvin, S Mbula, P Kom,

This paper explores how HIV-positive <i>abakhwetha</i> (young male initiates) undergoing <i>ulwaluko</i> (traditional Xhosa initiation and circumcision) engage with HIV-related biomedical care and treatment. Health-focused life history narratives (<i>n</i> = 36), semi-structured interviews (<i>n</i> = 32) and analysis of health facility files (<i>n</i> = 41) with adolescent boys and young men (ages 13-24) living with HIV, and ... Read more >>

SAHARA J (SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance)
[2021, 18(1):64-76]

Cited: 0 times

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Cross-protective immunity of the haemagglutinin stalk domain presented on the surface of Lactococcus lactis against divergent influenza viruses in mice.

Han Lei, Tong Gao, Qianhong Cen,

Most of the current approaches to influenza vaccine design focus on antibodies against influenza (HA). However, these influenza vaccines typically provide strain-specific protection against mostly homologous subtypes. There is an urgent need to develop a universal vaccine that confers cross-protection against influenza viruses. Of note, the HA stalk domain (HAsd) ... Read more >>

Virulence (Virulence)
[2021, 12(1):12-19]

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Project Last Mile and the development of the Girl Champ brand in eSwatini: engaging the private sector to promote uptake of health services among adolescent girls and young women.

Marie A Brault, Sarah Christie, Sasha Aquino, Abigail Rendin, Amanda Manchia, Leslie A Curry, Erika L Linnander,

In eSwatini and across sub-Saharan Africa, adolescent girls and young women (AGYW) are at significantly higher risk of HIV infection and poorer sexual and reproductive health (SRH) than their male counterparts. AGYW demonstrate low demand for SRH services, further contributing to poor outcomes. Strategic marketing approaches, including those used by ... Read more >>

SAHARA J (SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance)
[2021, 18(1):52-63]

Cited: 0 times

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Using molecular transmission networks to understand the epidemic characteristics of HIV-1 CRF08_BC across China.

Kang Li, Meiliang Liu, Huanhuan Chen, Jianjun Li, Yanling Liang, Yi Feng, Hui Xing, Yiming Shao,

HIV-1 CRF08_BC has become a major epidemic in heterosexuals and intravenous drug users (IDUs) in southern China. In order to evaluate the trends of its epidemic and facilitate targeted HIV prevention, we constructed the genetic transmission networks based on its <i>pol</i> sequences, derived from the National HIV Molecular Epidemiology Survey. ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):497-506]

Cited: 0 times

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Isolation and characterization of novel reassortant mammalian orthoreovirus from pigs in the United States.

Liping Wang, Yan Li, Timothy Walsh, Zhenyu Shen, Yonghai Li, Nirmalendu Deb Nath, Jinhwa Lee, Baoliang Zheng, Ying Tao, Clinton R Paden, Krista Queen, Shuping Zhang, Suxiang Tong, Wenjun Ma,

Mammalian orthoreovirus (MRV) infects multiple mammalian species including humans. A United States Midwest swine farm with approximately one thousand 3-month-old pigs experienced an event, in which more than 300 pigs showed neurological signs, like "down and peddling", with approximately 40% mortality. A novel MRV was isolated from the diseased pigs. ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1137-1147]

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Virus-associated ribozymes and nano carriers against COVID-19.

Beyza Dönmüş, Sinan Ünal, Fatma Ceren Kirmizitaş, Nelisa Türkoğlu Laçin,

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a zoo tonic, highly pathogenic virus. The new type of coronavirus with contagious nature spread from Wuhan (China) to the whole world in a very short time and caused the new coronavirus disease (COVID-19). COVID-19 has turned into a global public health ... Read more >>

Artif Cells Nanomed Biotechnol (Artificial cells, nanomedicine, and biotechnology)
[2021, 49(1):204-218]

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Seasonal dynamics and tissue distribution of two major viruses associated with grapevine Leafroll under cool climate condition

Mehdi Shabanian, Huogen Xiao, Baozhong Meng,

Grapevine leafroll-associated virus-2 (GLRaV-2) and GLRaV-3 are both (+) ssRNA viruses of the family Closteroviridae and are involved in grapevine leafroll, the most destructive viral disease affecting the global grape/wine industry. Outbreaks of the disease were recently reported in Canada, causing serious concerns to the grape/wine industry. Reliable, sensitive and ... Read more >>

Eur J Plant Pathol (European journal of plant pathology.)
[2021, 158(4):1017-1031]

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Domain in Fiber-2 interacted with KPNA3/4 significantly affects the replication and pathogenicity of the highly pathogenic FAdV-4.

Quan Xie, Weikang Wang, Luyuan Li, Qiuqi Kan, Hui Fu, Tuoyu Geng, Tuofan Li, Zhimin Wan, Wei Gao, Hongxia Shao, Aijian Qin, Jianqiang Ye,

The outbreaks of hepatitis-hydropericardium syndrome (HPS) caused by the highly pathogenic serotype 4 fowl adenovirus (FAdV-4) have caused a huge economic loss to the poultry industry globally since 2013. Although the Fiber-2 has been identified as a key virulent related factor for FAdV-4, little is known about its molecular basis. In ... Read more >>

Virulence (Virulence)
[2021, 12(1):754-765]

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