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Vertebral Artery Atherothrombosis

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High-risk NSTEMI due to Subclavian Artery Atherothrombosis in a Prior Coronary Artery Bypass Graft Patient.

Michele Coceani, Francesco Sbrana, Marco Ciardetti, Beatrice Dal Pino, Cataldo Palmieri, Sergio Berti, Alberto Giannoni, Michele Emdin, Tiziana Sampietro,

J Cardiovasc Echogr (Journal of cardiovascular echography)
[2019, 29(2):86-87]

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Emergency Superficial Temporal Artery-Superior Cerebellar Artery Bypass for the Refractory Vertebrobasilar Insufficiency with Partial Mastoidectomy.

Makoto Katsuno, Eitaro Ishisaka, Kiyotaka Toyota, Kazutsune Kawasaki, Izumi Inaba,

BACKGROUND:Although it is well-known that vertebrobasilar insufficiency (VBI) because of atherothrombosis with bilateral vertebral artery (VA) occlusion is resistant to medical treatment from the acute to subacute stages, the most appropriate treatment for progressive infarction at these stages remains unclear. Here, we described a patient with VBI who underwent emergency ... Read more >>

World Neurosurg (World neurosurgery)
[2018, 118:75-80]

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Sweet dreams: How mini-invasive surgery tackles obstructive sleep apnea.

Sophia Julia Häfner,

In this issue of the Biomedical Journal we uncover how the discovery of tyrosine phosphorylation thirty years ago led to the recent development of potent cancer drugs. Furthermore we learn about the state of the art of surgery for obstructive sleep apnea and how modern automated hematology could be used ... Read more >>

Biomed J (Biomedical journal)
[2019, 42(2):75-79]

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Association between etiology and lesion site in ischemic brainstem infarcts: a retrospective observational study.

Gozde Baran, Tugce Ozdemir Gultekin, Oguz Baran, Cigdem Deniz, Salim Katar, Gulsen Babacan Yildiz, Talip Asil,

To assess the anatomical distribution of the ischemic strokes of the brainstem, the effect of anatomical distribution on clinical features and prognosis, and the association between etiology and anatomical involvement.A retrospective search of the patient database of our institution was performed for a total of 227 patients who were admitted ... Read more >>

Neuropsychiatr Dis Treat (Neuropsychiatric Disease and Treatment)
[2018, 14:757-766]

Cited: 1 time

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Atheroma of the Innominate Artery Presenting as a Transient Ischemic Attack.

Moin Hassan, Ateeq Mubarik, Chirag Patel, Furqan Haq, Salman Muddassir,

Supra-aortic atherosclerotic lesions, including innominate artery atheromas, are an uncommon but established cause of transient ischemic attacks, stroke, upper extremity ischemia, and vertebrobasilar insufficiency. We present a patient with a transient ischemic attack admitted with right hemispheric symptoms who was found to have a severe ulcerated innominate artery atheroma. The ... Read more >>

Cureus (Cureus)
[2019, 11(1):e3961]

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Outcomes of Endovascular Thrombectomy Performed 6-24 h after Acute Stroke from Extracranial Internal Carotid Artery Occlusion.

Eitaro Okumura, Junya Tsurukiri, Takahiro Ota, Hiroyuki Jimbo, Keigo Shigeta, Tatsuo Amano, Masayuki Ueda, Yuji Matsumaru, Yoshiaki Shiokawa, Teruyuki Hirano,

Thrombectomy has demonstrated clinical efficacy against acute ischemic stroke caused by intracranial occlusion of the internal carotid artery (ICA), even if performed 6-24 h after onset. This study investigated the outcomes of thrombectomy performed 6-24 h after stroke onset caused by extracranial ICA occlusion. Of 586 stroke patients receiving thrombectomy ... Read more >>

Neurol. Med. Chir. (Tokyo) (Neurologia medico-chirurgica)
[2019, 59(9):337-343]

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Small obliquely oriented cortical cerebellar infarctions are associated with cardioembolic stroke.

Adrien Ter Schiphorst, Lavinia Tatu, Vincent Thijs, Christophe Demattei, Eric Thouvenot, Dimitri Renard,

BACKGROUND:A revised classification of cerebellar infarctions (CI) may uncover unrecognized associations with etiologic stroke subtypes. We hypothesized that obliquely oriented small cortical cerebellar infarction (SCCI) representing end zone infarctions on MRI would be associated with cardiac embolism. METHODS:We retrospectively analyzed consecutive stroke patients recruited between January-December 2016 in our center. ... Read more >>

BMC Neurol (BMC neurology)
[2019, 19(1):100]

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Calcium antagonists for acute ischemic stroke.

Jing Zhang, Jia Liu, Dan Li, Canfei Zhang, Ming Liu,

BACKGROUND:The sudden loss of blood supply in ischemic stroke is associated with an increase of calcium ions within neurons. Inhibiting this increase could protect neurons and might reduce neurological impairment, disability, and handicap after stroke. OBJECTIVES:To assess the effects of calcium antagonists for reducing the risk of death or dependency ... Read more >>

Cochrane Database Syst Rev (The Cochrane database of systematic reviews)
[2019, 2:CD001928]

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Platelets Are at the Nexus of Vascular Diseases.

Héloïse Lebas, Katia Yahiaoui, Raphaël Martos, Yacine Boulaftali,

Platelets are important actors of cardiovascular diseases (CVD). Current antiplatelet drugs that inhibit platelet aggregation have been shown to be effective in CVD treatment. However, the management of bleeding complications is still an issue in vascular diseases. While platelets can act individually, they interact with vascular cells and leukocytes at ... Read more >>

Front Cardiovasc Med (Frontiers in cardiovascular medicine)
[2019, 6:132]

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Endovascular and Clinical Outcomes of Vertebrobasilar Intracranial Atherosclerosis-Related Large Vessel Occlusion.

Jang-Hyun Baek, Byung Moon Kim, Ji Hoe Heo, Dong Joon Kim, Hyo Suk Nam, Young Dae Kim,

Background and Purpose: Endovascular treatment (EVT) for acute vertebrobasilar intracranial atherosclerosis-related large vessel occlusion (ICAS-LVO) and its outcomes are not well known. We aimed to evaluate endovascular and clinical outcomes of vertebrobasilar ICAS-LVO patients who underwent EVT. Methods: Consecutive acute stroke patients who underwent EVT for vertebrobasilar LVO were retrospectively ... Read more >>

Front Neurol (Frontiers in Neurology)
[2019, 10:215]

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Thromboxane-Dependent Platelet Activation in Obese Subjects with Prediabetes or Early Type 2 Diabetes: Effects of Liraglutide- or Lifestyle Changes-Induced Weight Loss.

Paola Simeone, Rossella Liani, Romina Tripaldi, Augusto Di Castelnuovo, Maria Teresa Guagnano, Armando Tartaro, Riccardo C Bonadonna, Virginia Federico, Francesco Cipollone, Agostino Consoli, Francesca Santilli,

Thromboxane (TX)-dependent platelet activation and lipid peroxidation, as reflected in vivo by the urinary excretion of 11-dehydro-TXB₂ and 8-iso-prostaglandin (PG)F2α, play a key role in atherothrombosis in obesity and type 2 diabetes mellitus (T2DM) since the earlier stages. Thirty-five metformin-treated obese subjects with prediabetes or newly-diagnosed T2DM were randomized to ... Read more >>

Nutrients (Nutrients)
[2018, 10(12):]

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Characteristics of Spontaneous Spinal Cord Infarction and Proposed Diagnostic Criteria.

Nicholas L Zalewski, Alejandro A Rabinstein, Karl N Krecke, Robert D Brown, Eelco F M Wijdicks, Brian G Weinshenker, Timothy J Kaufmann, Jonathan M Morris, Allen J Aksamit, J D Bartleson, Giuseppe Lanzino, Melissa M Blessing, Eoin P Flanagan,

Importance:Spinal cord infarction (SCI) is often disabling, and the diagnosis can be challenging without an inciting event (eg, aortic surgery). Patients with a spontaneous SCI are often misdiagnosed as having transverse myelitis. Diagnostic criteria for SCI are lacking, hindering clinical care and research. Objective:To describe the characteristics of spontaneous SCI ... Read more >>

JAMA Neurol (JAMA neurology)
[2019, 76(1):56-63]

Cited: 4 times

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Different Strokes: A management dilemma.

Arunodaya R Gujjar, Mortada El-Tigani, Darshan Lal, Anupam K Kakaria, Abdullah R Al-Asmi,

Stroke is a common medical emergency resulting from numerous pathophysiological mechanisms and with varied clinical manifestations; as such, the diagnosis of stroke requires diligent clinical assessment. When different stroke syndromes occur in the same patient, it may cause a dilemma in terms of diagnosis and management. This continuing medical education ... Read more >>

Sultan Qaboos Univ Med J (Sultan Qaboos University medical journal)
[2018, 18(2):e202-e207]

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Relationship between the geometry patterns of vertebrobasilar artery and atherosclerosis.

Jin Yu, Shu Zhang, Ming-Li Li, Yi Ma, Yu-Ru Dong, Min Lou, Feng Feng, Shan Gao, Shi-Wen Wu, Wei-Hai Xu,

The plaques at the dorsal or lateral wall of basilar artery (BA) are associated with pontine infarcts. We sought to explore the correlations between vertebrobasilar artery geometry and BA plaque locations.We retrospectively analyzed the imaging and clinical data of 84 patients with BA atherosclerosis. On three-dimensional time-of-flight images, a side ... Read more >>

BMC Neurol (BMC neurology)
[2018, 18(1):83]

Cited: 2 times

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Role of Noninvasive Imaging of Cerebral Arterial System in Ischemic Stroke: Comparison of Transcranial Color-coded Doppler Sonography with Magnetic Resonance Angiography.

Betty Simon, Sunithi Elizabeth Mani, Shyamkumar Nidugala Keshava, Mathew Alexander, Sanjith Aaron,

Aim:To determine the accuracy of transcranial color-coded Doppler sonography (TCCS) in the evaluation of cerebral arterial system in patients with ischemic stroke attending a tertiary care hospital in South India. Objectives:(1) To describe the topographical distribution of atherosclerotic lesions in the cerebral circulation in patients presenting with ischemic stroke from ... Read more >>

J Clin Imaging Sci (Journal of clinical imaging science)
[2018, 8:19]

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Periodontitis and cardiovascular diseases: Consensus report.

Mariano Sanz, Alvaro Marco Del Castillo, Søren Jepsen, Jose R Gonzalez-Juanatey, Francesco D'Aiuto, Philippe Bouchard, Iain Chapple, Thomas Dietrich, Israel Gotsman, Filippo Graziani, David Herrera, Bruno Loos, Phoebus Madianos, Jean-Baptiste Michel, Pablo Perel, Burkert Pieske, Lior Shapira, Michael Shechter, Maurizio Tonetti, Charalambos Vlachopoulos, Gernot Wimmer,

BACKGROUND:In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non-communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of ... Read more >>

J. Clin. Periodontol. (Journal of clinical periodontology)
[2020, 47(3):268-288]

Cited: 0 times

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Intracranial atherosclerotic disease.

Yuan Wang, Ran Meng, Gang Liu, Catherine Cao, Fenghua Chen, Kunlin Jin, Xunming Ji, Guodong Cao,

Intracranial atherosclerosis (ICAS) is a progressive pathological process that causes progressive stenosis and cerebral hypoperfusion and is a major cause of stroke occurrence and recurrence around the world. Multiple factors contribute to the development of ICAS. Angiography imaging techniques can improve the diagnosis of and the selection of appropriate treatment ... Read more >>

Neurobiol. Dis. (Neurobiology of disease)
[2019, 124:118-132]

Cited: 1 time

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ESICON 2019 Abstracts.

(Indian Journal of Endocrinology and Metabolism)
[2019, 23(Suppl 1):S5-S83]

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High CD3+ Cells in Intracranial Thrombi Represent a Biomarker of Atherothrombotic Stroke.

Cyril Dargazanli, Valérie Rigau, Omer Eker, Carlos Riquelme Bareiro, Paolo Machi, Grégory Gascou, Caroline Arquizan, Xavier Ayrignac, Isabelle Mourand, Astrid Corlobé, Kyriakos Lobotesis, Nicolas Molinari, Valérie Costes, Alain Bonafé, Vincent Costalat,

BACKGROUND AND PURPOSE:Approximately 30% of strokes are cryptogenic despite an exhaustive in-hospital work-up. Analysis of clot composition following endovascular treatment could provide insight into stroke etiology. T-cells already have been shown to be a major component of vulnerable atherosclerotic carotid lesions. We therefore hypothesize that T-cell content in intracranial thrombi ... Read more >>

PLoS ONE (PloS one)
[2016, 11(5):e0154945]

Cited: 10 times

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Color Doppler Ultrasonography Is a Useful Tool for Diagnosis of Peripheral Artery Disease in Type 2 Diabetes Mellitus Patients with Ankle-Brachial Index 0.91 to 1.40.

Kyu Yeon Hur, Ji Eun Jun, Young Ju Choi, Yong Ho Lee, Dae Jung Kim, Seok Won Park, Byung Wook Huh, Eun Jig Lee, Sun Ha Jee, Kap Bum Huh, Sung Hee Choi,

The clinical utility of ankle-brachial index (ABI) is not clear in subjects with less severe or calcified vessel. Therefore, we investigated the usefulness of color Doppler ultrasonography for diagnosing peripheral artery disease (PAD) in type 2 diabetes mellitus (T2DM) subjects.We analyzed 324 T2DM patients who concurrently underwent ABI and carotid ... Read more >>

Diabetes Metab J (Diabetes & metabolism journal)
[2018, 42(1):63-73]

Cited: 1 time

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One-year follow-up in patients with brainstem infarction due to large-artery atherothrombosis.

Mehmet Kolukısa, Tugce Ozdemir Gültekin, Gozde Eryigit Baran, Ayse Aralasmak, Gülsen Kocaman, Azize Esra Gürsoy, Talip Asil,

BACKGROUND: Posterior circulation infarction accounts for approximately 25% of the ischemic strokes. A number of different conditions may be associated with the development of brainstem infarction. Prognosis and recurrence rate of brainstem infarction due to large-artery atherothrombosis is still controversial. METHODS: A total of 826 patients with ischemic stroke were ... Read more >>

Neuropsychiatr Dis Treat (Neuropsychiatric Disease and Treatment)
[2015, 11:379-384]

Cited: 1 time

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Impact of Traumatic Lower Extremity Injuries Beyond Acute Care: Movement-Based Considerations for Resultant Longer Term Secondary Health Conditions.

Courtney M Butowicz, Christopher L Dearth, Brad D Hendershot,

Significance: Advances in field-based trauma care, surgical techniques, and protective equipment have collectively facilitated the survival of a historically large number of service members (SMs) following combat trauma, although many sustained significant composite tissue injuries to the extremities, including limb loss (LL) and limb salvage (LS). Beyond the acute surgical ... Read more >>

Adv Wound Care (New Rochelle) (Advances in wound care)
[2017, 6(8):269-278]

Cited: 1 time

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Catheter-based interventions for acute ischaemic stroke.

Petr Widimsky, L Nelson Hopkins,

Catheter-based interventions for acute ischaemic stroke currently include clot removal (usually from the medial cerebral artery) with modern stent-retrievers and in one of five patients (who have simultaneous or stand-alone internal carotid occlusion) also extracranial carotid intervention. Several recently published randomized trials clearly demonstrated superiority of catheter-based interventions (with or ... Read more >>

Eur. Heart J. (European heart journal)
[2016, 37(40):3081-3089]

Cited: 5 times

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Role of Hyperintense Acute Reperfusion Marker for Classifying the Stroke Etiology.

Hee Young Choi, Kyung Mi Lee, Hyug-Gi Kim, Eui Jong Kim, Woo Suk Choi, Bum Joon Kim, Sung Hyuk Heo, Dae-Il Chang,

The hyperintense acute reperfusion marker (HARM) is a delayed enhancement of the subarachnoid or subpial space observed on post-contrast fluid-attenuated inversion recovery (FLAIR) images and is associated with permeability changes to the blood-brain barrier in acute stroke. We investigated the relationship between HARM and stroke etiology based on the Trial ... Read more >>

Front Neurol (Frontiers in neurology)
[2017, 8:630]

Cited: 0 times

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Risk factor profile by etiological subtype of ischemic stroke in the young.

Aude Jaffre, Jean Bernard Ruidavets, Lionel Calviere, Alain Viguier, Jean Ferrieres, Vincent Larrue,

BACKGROUND AND PURPOSE: Studies of risk factors for ischemic stroke in the young have generally considered ischemic stroke as a whole. The purpose of the present study was to evaluate the association of traditional cardiovascular risk factors with etiological subtypes of ischemic stroke in young adults. METHODS: Retrospective review of ... Read more >>

Clin Neurol Neurosurg (Clinical neurology and neurosurgery)
[2014, 120:78-83]

Cited: 7 times

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