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Hysteresis Loop Can be an Adjunct Monitoring for Neuromuscular Blockade while on Controlled Ventilation During Low- and Minimal-Flow Anaesthesia.

Habib Md Reazaul Karim,

Turk J Anaesthesiol Reanim (Turkish journal of anaesthesiology and reanimation)
[2020, 48(1):84-85]

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Ventilated Infants Have Increased Dead Space and Lower Alveolar Tidal Volumes during the Early versus Recovery Phase of Respiratory Distress.

Masashi Zuiki, Akio Yamano, Kazumasa Kitamura, Takeshi Goda, Satoshi Oya, Hiroshi Komatsu,

BACKGROUND:Few studies have reported the measurement of anatomical dead space (Vd,an) and alveolar tidal volume (VA) in ventilated neonates with respiratory distress. OBJECTIVE:The aim of this study was to determine the differences in Vd,an and VA in ventilated infants between the early and recovery phases of respiratory distress using volumetric ... Read more >>

Neonatology (Neonatology)
[2019, :1-4]

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Extracorporeal carbon dioxide removal in heart-beating donor with acute severe asthma: A case report.

Silvia De Rosa, Gianlorenzo Golino, Claudio Ronco,

Status asthmaticus is a life-threatening disorder that can manifest in dangerous levels of hypercapnia and acidosis. The use of extracorporeal carbon dioxide removal (ECCO2R) has been used successfully to control pH and PaCO2 in patients with acute severe asthma. The present report describes the use of this technology in near-fatal ... Read more >>

Respir Med Case Rep (Respiratory medicine case reports)
[2020, 29:101010]

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Prevention and treatment of acute lung injury with time-controlled adaptive ventilation: physiologically informed modification of airway pressure release ventilation.

Gary F Nieman, Louis A Gatto, Penny Andrews, Joshua Satalin, Luigi Camporota, Benjamin Daxon, Sarah J Blair, Hassan Al-Khalisy, Maria Madden, Michaela Kollisch-Singule, Hani Aiash, Nader M Habashi,

Mortality in acute respiratory distress syndrome (ARDS) remains unacceptably high at approximately 39%. One of the only treatments is supportive: mechanical ventilation. However, improperly set mechanical ventilation can further increase the risk of death in patients with ARDS. Recent studies suggest that ventilation-induced lung injury (VILI) is caused by exaggerated ... Read more >>

Ann Intensive Care (Annals of intensive care)
[2020, 10(1):3]

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Patient-ventilator asynchronies: types, outcomes and nursing detection skills.

Enrico Bulleri, Cristian Fusi, Stefano Bambi, Luigi Pisani,

BACKGROUND:Mechanical ventilation is often employed as partial ventilatory support where both the patient and the ventilator work together. The ventilator settings should be adjusted to maintain a harmonious patient-ventilator interaction. However, this balance is often altered by many factors able to generate a patient ventilator asynchrony (PVA). The aims of ... Read more >>

Acta Biomed (Acta bio-medica : Atenei Parmensis)
[2018, 89(7-S):6-18]

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[Early recognition of postoperative complications on normal wards : Continuous wireless monitoring for identification of patients at risk].

J-C Schewe,

Anaesthesist (Der Anaesthesist)
[2020, 69(1):1-2]

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The Joint Mobile Emerging Disease Clinical Capability (JMEDICC) laboratory approach: Capabilities for high-consequence pathogen clinical research.

Prossy Naluyima, Willy Kayondo, Chi Ritchie, Joseph Wandege, Sharon Kagabane, Lydia Tumubeere, Brenda Kusiima, Daniel Kibombo, Sharon Atukunda, Christine Nanteza, Harriet Nabirye, Francis Bunjo Mugabi, Sarah Namuyanja, Christopher Hatcher, Hypaitia Rauch, Moses Mukembo, Patrick Musinguzi, , Nathan Sanders, Elizabeth Turesson, Christian Cando, Richard Walwema, Derrick Mimbe, Janice Hepburn, Danielle Clark, Mohammed Lamorde, Hannah Kibuuka, Saima Zaman, Anthony P Cardile, Karen A Martins,

Following the 2013-2016 Ebola virus outbreak in West Africa, numerous groups advocated for the importance of executing clinical trials in outbreak settings. The difficulties associated with obtaining reliable data to support regulatory approval of investigational vaccines and therapeutics during that outbreak were a disappointment on a research and product development ... Read more >>

PLoS Negl Trop Dis (PLoS neglected tropical diseases)
[2019, 13(12):e0007787]

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Neurally adjusted ventilatory assist mitigates ventilator-induced diaphragm injury in rabbits.

Tatsutoshi Shimatani, Nobuaki Shime, Tomohiko Nakamura, Shinichiro Ohshimo, Justin Hotz, Robinder G Khemani,

BACKGROUND:Ventilator-induced diaphragmatic dysfunction is a serious complication associated with higher ICU mortality, prolonged mechanical ventilation, and unsuccessful withdrawal from mechanical ventilation. Although neurally adjusted ventilatory assist (NAVA) could be associated with lower patient-ventilator asynchrony compared with conventional ventilation, its effects on diaphragmatic dysfunction have not yet been well elucidated. METHODS:Twenty ... Read more >>

Respir. Res. (Respiratory research)
[2019, 20(1):293]

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Effect of PEEP on inspiratory resistance components in patients with acute respiratory distress syndrome ventilated at low tidal volume.

Sebastian Fredes, Emilio Steinberg, Norberto Tiribelli, Analia Santa Maria, Mariana Berté, Nicolás Segura, Diego Noval, Santiago Ilutovich,

OBJECTIVE:To describe the behavior of inspiratory resistance components when positive end-expiratory pressure (PEEP) increases in patients with acute respiratory distress syndrome under a protective ventilation strategy. METHODS:In volume-controlled mode, at 6mL/kg and constant flow, end-inspiratory occlusions were performed at 0, 5 10, 15 and 20cmH2O PEEP. Peak, initial and plateau ... Read more >>

Rev Bras Ter Intensiva (Revista Brasileira de terapia intensiva)
[2019, 31(4):483-489]

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Esophageal pressure balloon and transpulmonary pressure monitoring in airway pressure release ventilation: a different approach.

Ehab G Daoud, Kimiyo H Yamasaki, Keith Nakamoto, Denise Wheatley,

This is a case of Acute Respiratory Distress Syndrome managed using esophageal balloon catheter to adjust inspiratory pressure and positive end expiratory pressure according to the inspiratory and expiratory transpulmonary pressures. There are no studies that examine the transpulmonary pressures in airway pressure release ventilation (APRV). We aimed to test ... Read more >>

Can J Respir Ther (Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR)
[2018, 54(3):62-65]

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Atorvastatin combined with routine therapy on HIF-1, VEGF concentration and cardiac function in rats with acute myocardial infarction.

Jingbin Yu, Lei Zhang, Hui Zhang,

Effect of atorvastatin combined with routine therapy on the expression of hypoxia inducible factor (HIF-1) and vascular endothelial growth factor (VEGF) in rats with acute myocardial infarction (AMI) and its therapeutic effect were investigated. The rat models of acute myocardial infarction were established and divided into routine therapy, study, model, ... Read more >>

Exp Ther Med (Experimental and therapeutic medicine)
[2020, 19(3):2053-2058]

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Optimizing imaging of the rat pulmonary microvasculature by micro-computed tomography.

Yupu Deng, Katelynn J Rowe, Ketul R Chaudhary, Anli Yang, Shirley H J Mei, Duncan J Stewart,

Micro-computed tomography (micro-CT) is used in pre-clinical research to generate high-resolution three-dimensional (3D) images of organs and tissues. When combined with intravascular contrast agents, micro-CT can provide 3D visualization and quantification of vascular networks in many different organs. However, the lungs present a particular challenge for contrast perfusion due to ... Read more >>

Pulm Circ (Pulmonary circulation)
[2019, 9(4):2045894019883613]

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Modification on acute myocardial infarction model through left anterior descending coronary artery ligation: An experimental study on rats (Rattus norvegicus) using readily available materials.

Johanes Nugroho, Wiwik Misaco Yuniarti, Ardyan Wardhana, Cornelia Ghea,

Background and Aim:Several difficulties are involved in creating models for myocardial infarction (MI) in animals, such as low survival rates after acute MI, complicated techniques in creating animal models, complexities in confirming acute MI incidence, and complex surgical tools needed in the process. This study aimed to develop an animal ... Read more >>

Vet World (Veterinary World)
[2019, 12(9):1448-1453]

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Development and validation of a predictive model for American Society of Anesthesiologists Physical Status.

Seshadri C Mudumbai, Suzann Pershing, Thomas Bowe, Robin N Kamal, Erika D Sears, Andrea K Finlay, Dan Eisenberg, Mary T Hawn, Yingjie Weng, Amber W Trickey, Edward R Mariano, Alex H S Harris,

BACKGROUND:The American Society of Anesthesiologists Physical Status (ASA-PS) classification system was developed to categorize the fitness of patients before surgery. Increasingly, the ASA-PS has been applied to other uses including justification of inpatient admission. Our objectives were to develop and cross-validate a statistical model for predicting ASA-PS; and 2) assess ... Read more >>

BMC Health Serv Res (BMC health services research)
[2019, 19(1):859]

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Application of Deep Learning System into the Development of Communication Device for Quadriplegic Patient.

Jung Hwan Lee, Taewoo Kang, Byung Kwan Choi, In Ho Han, Byung Chul Kim, Jung Hoon Ro,

Objective:In general, quadriplegic patients use their voices to call the caregiver. However, severe quadriplegic patients are in a state of tracheostomy, and cannot generate a voice. These patients require other communication tools to call caregivers. Recently, monitoring of eye status using artificial intelligence (AI) has been widely used in various ... Read more >>

Korean J Neurotrauma (Korean journal of neurotrauma)
[2019, 15(2):88-94]

Cited: 1 time

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Micro-CT of tracheal stenosis in trisomy 21.

Susan C Shelmerdine, Michael T Ashworth, Alistair D Calder, Nagarajan Muthialu, Owen J Arthurs,

Thorax (Thorax)
[2019, 74(4):419-420]

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MPPED2 Polymorphism Is Associated With Altered Systemic Inflammation and Adverse Trauma Outcomes.

Lukas Schimunek, Rami A Namas, Jinling Yin, Derek Barclay, Dongmei Liu, Fayten El-Dehaibi, Andrew Abboud, Maria Cohen, Ruben Zamora, Timothy R Billiar, Yoram Vodovotz,

Trauma is a leading cause of morbidity and mortality. It is unclear why some trauma victims follow a complicated clinical course and die, while others, with apparently similar injury characteristics, do not. Interpatient genomic differences, in the form of single nucleotide polymorphisms (SNPs), have been associated previously with adverse outcomes ... Read more >>

Front Genet (Frontiers in genetics)
[2019, 10:1115]

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Clinical course, mutations and its functional characteristics of infantile-onset Pompe disease in Thailand.

Lukana Ngiwsara, Duangrurdee Wattanasirichaigoon, Thipwimol Tim-Aroon, Kitiwan Rojnueangnit, Saisuda Noojaroen, Arthaporn Khongkraparn, Phannee Sawangareetrakul, James R Ketudat-Cairns, Ratana Charoenwattanasatien, Voraratt Champattanachai, Chulaluck Kuptanon, Suthipong Pangkanon, Jisnuson Svasti,

BACKGROUND:Pompe disease is a lysosomal storage disorder caused by the deficiency of acid alpha-glucosidase (EC. 3.2.1.20) due to mutations in human GAA gene. The objective of the present study was to examine clinical and molecular characteristics of infantile-onset Pompe disease (IOPD) in Thailand. METHODS:Twelve patients with infantile-onset Pompe disease (IOPD) ... Read more >>

BMC Med. Genet. (BMC medical genetics)
[2019, 20(1):156]

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Laryngoscope-assisted and cotton ball wiping methods in prevention of oral and pulmonary infection in patients receiving mechanical ventilation and the influence on hypersensitive C-reactive protein and procalcitonin.

Pingji Zhang, Guoguang Xia, Li Dai, Yang Cheng, Zhuo Wang,

Effects of laryngoscope-assisted and cotton ball wiping methods on the prevention of oral and pulmonary infection in patients receiving mechanical ventilation were compared to explore the influence of the two methods on high-sensitivity C-reactive protein (hs-CRP) and procalcitonin (PCT). In total, 152 patients who underwent mechanical ventilation in the ICU ... Read more >>

Exp Ther Med (Experimental and therapeutic medicine)
[2019, 18(1):531-536]

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Full Outline of UnResponsiveness score versus Glasgow Coma Scale in critically ill patients with altered sensorium: A comparison of inter-observer variability and outcomes.

Varun Suresh, Lakshmi Narayana Yaddanapudi, Subrata Podder,

Background and Aims:Glasgow Coma scale (GCS), the most widely used tool for evaluation of the level of consciousness has various limitations. The Full Outline of UnResponsiveness (FOUR) score is a possible alternative. The present study was designed to examine the inter-rater reliability and outcome predictability of these scores in the ... Read more >>

Indian J Anaesth (Indian journal of anaesthesia)
[2019, 63(8):640-647]

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A Review of Electrical Impedance Tomography in Lung Applications: Theory and Algorithms for Absolute Images.

Thiago de Castro Martins, André Kubagawa Sato, Fernando Silva de Moura, Erick Dario León Bueno de Camargo, Olavo Luppi Silva, Talles Batista Rattis Santos, Zhanqi Zhao, Knut Möeller, Marcelo Brito Passos Amato, Jennifer L Mueller, Raul Gonzalez Lima, Marcos de Sales Guerra Tsuzuki,

Electrical Impedance Tomography (EIT) is under fast development, the present paper is a review of some procedures that are contributing to improve spatial resolution and material properties accuracy, admitivitty or impeditivity accuracy. A review of EIT medical applications is presented and they were classified into three broad categories: ARDS patients, ... Read more >>

Annu Rev Control (Annual reviews in control)
[2019, 48:442-471]

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Reverse triggering induced by endotracheal tube leak in lightly sedated ARDS patient.

Taiga Itagaki, Yoshitoyo Ueno, Nobuto Nakanishi, Jun Oto,

Reverse triggering is respiratory entrainment triggered by the ventilator especially seen among heavily sedated patients. We confirmed reverse triggering induced by auto-triggering in lightly sedated patient through an esophageal pressure monitoring. The reverse triggering frequently caused breath stacking with increased tidal volume. Physicians should be aware, even at an optimal ... Read more >>

J Intensive Care (Journal of Intensive Care)
[2018, 6:41]

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Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT.

Jennie Johnstone, Diane Heels-Ansdell, Lehana Thabane, Maureen Meade, John Marshall, Francois Lauzier, Erick Huaileigh Duan, Nicole Zytaruk, Daphnee Lamarche, Michael Surette, Deborah J Cook, ,

INTRODUCTION:Ventilator-associated pneumonia (VAP) is the most common healthcare-associated infection in critically ill patients. Prior studies suggest that probiotics may reduce VAP and other infections in critically ill patients; however, most previous randomised trials were small, single centre studies. The Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT) aims ... Read more >>

BMJ Open (BMJ open)
[2019, 9(6):e025228]

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Paralyzed by Mistakes - Reassess the Safety of Neuromuscular Blockers in Your Facility.

Matthew Grissinger,

Neuromuscular blockers have been inadvertently administered to patients who were not receiving proper ventilatory assistance, causing death or permanent injuries. ... Read more >>

P T (P & T : a peer-reviewed journal for formulary management)
[2019, 44(3):91-107]

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Ventilator auto-triggering by cardiac electrical activity during noninvasive ventilation with neurally adjusted ventilatory assist.

Yu Inata, Muneyuki Takeuchi,

Neurally adjusted ventilatory assist (NAVA), by capturing the electrical activity of the diaphragm, improves patient-ventilator synchrony. It is, however, not completely immune from auto-triggering by cardiac electrical activity as illustrated in this case. Stringent observation of respiratory rate and vigilance for this phenomenon is warranted when using NAVA. ... Read more >>

Clin Case Rep (Clinical case reports)
[2018, 6(7):1379-1380]

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