Full Text Journal Articles about
Vaccines

Advertisement

Find full text journal articles






Cross-protective immunity of the haemagglutinin stalk domain presented on the surface of Lactococcus lactis against divergent influenza viruses in mice.

Han Lei, Tong Gao, Qianhong Cen,

Most of the current approaches to influenza vaccine design focus on antibodies against influenza (HA). However, these influenza vaccines typically provide strain-specific protection against mostly homologous subtypes. There is an urgent need to develop a universal vaccine that confers cross-protection against influenza viruses. Of note, the HA stalk domain (HAsd) ... Read more >>

Virulence (Virulence)
[2021, 12(1):12-19]

Cited: 0 times

View full text PDF listing >>



Where are the RNA vaccines for TB?

Xiao-Yong Fan, Douglas Bruce Lowrie,

A simple mRNA vaccine was shown to protect mice against tuberculosis more than 15 years ago. Like COVID-19, tuberculosis is a respiratory infection killing over a million people per year. It too presents a global emergency. Can the stunning success of RNA vaccination against COVID-19 be replicated for TB? ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1217-1218]

Cited: 0 times

View full text PDF listing >>



Advertisement

A novel DNA and protein combination COVID-19 vaccine formulation provides full protection against SARS-CoV-2 in rhesus macaques.

Yuzhong Li, Yanwei Bi, Hongjian Xiao, Yueting Yao, Xiaojuan Liu, Zhengrong Hu, Jinmei Duan, Yaoyun Yang, Zhihua Li, Yadong Li, Heng Zhang, Chen Ding, Jianbo Yang, Haiwei Li, Zhanlong He, Longding Liu, Guangnan Hu, Shuying Liu, Yanchun Che, Shixia Wang, Qihan Li, Shan Lu, Wei Cun,

The current study aims to develop a safe and highly immunogenic COVID-19 vaccine. The novel combination of a DNA vaccine encoding the full-length Spike (S) protein of SARS-CoV-2 and a recombinant S1 protein vaccine induced high level neutralizing antibody and T cell immune responses in both small and large animal ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):342-355]

Cited: 2 times

View full text PDF listing >>



Prime-boost vaccination of mice and rhesus macaques with two novel adenovirus vectored COVID-19 vaccine candidates.

Shengxue Luo, Panli Zhang, Bochao Liu, Chan Yang, Chaolan Liang, Qi Wang, Ling Zhang, Xi Tang, Jinfeng Li, Shuiping Hou, Jinfeng Zeng, Yongshui Fu, Jean-Pierre Allain, Tingting Li, Yuming Zhang, Chengyao Li,

<b>ABSTRACT</b>COVID-19 vaccines are being developed urgently worldwide. Here, we constructed two adenovirus vectored COVID-19 vaccine candidates of Sad23L-nCoV-S and Ad49L-nCoV-S carrying the full-length gene of SARS-CoV-2 spike protein. The immunogenicity of two vaccines was individually evaluated in mice. Specific immune responses were observed by priming in a dose-dependent manner, and ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1002-1015]

Cited: 1 time

View full text PDF listing >>



Human challenge trials to assess the efficacy of currently approved COVID-19 vaccines against SARS-CoV-2 variants.

Shan Su, Yiming Shao, Shibo Jiang,

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):439-441]

Cited: 2 times

View full text PDF listing >>



Heterologous prime-boost: breaking the protective immune response bottleneck of COVID-19 vaccine candidates.

Qian He, Qunying Mao, Chaoqiang An, Jialu Zhang, Fan Gao, Lianlian Bian, Changgui Li, Zhenglun Liang, Miao Xu, Junzhi Wang,

COVID-19 vaccines emerging from different platforms differ in efficacy, duration of protection, and side effects. To maximize the benefits of vaccination, we explored the utility of employing a heterologous prime-boost strategy in which different combinations of the four types of leading COVID-19 vaccine candidates that are undergoing clinical trials in ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):629-637]

Cited: 0 times

View full text PDF listing >>



Support among healthcare workers for the new mandatory seasonal influenza vaccination policy and its effects on vaccination coverage.

Aleksi Hämäläinen, Riitta-Liisa Patovirta, Ella Mauranen, Sari Hämäläinen, Irma Koivula,

<h4>Introduction</h4>Finland was the first European country to introduce a nation-wide mandatory seasonal influenza vaccination policy for healthcare workers (HCWs) by mandating that administrators of health care institutions only employ vaccinated HCWs. In this study, we examine the effects of the new policy and the view of HCWs on the new ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):384-390]

Cited: 0 times

View full text PDF listing >>



DNA priming immunization is more effective than recombinant protein vaccine in eliciting antigen-specific B cell responses.

Haiying Li, Shixia Wang, Guangnan Hu, Lu Zhang, Shuying Liu, Shan Lu,

While DNA prime-protein boost vaccination approach has been widely used in preclinical and clinical studies especially in the field of HIV vaccine development, the exact role of DNA immunization has not been fully identified. Our previous work demonstrated that DNA immunization was able to elicit T follicular helper (Tfh) cell ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):833-841]

Cited: 0 times

View full text PDF listing >>



The epidemiological characteristics of enterovirus infection before and after the use of enterovirus 71 inactivated vaccine in Kunming, China.

Hongchao Jiang, Zhen Zhang, Qing Rao, Xiaodan Wang, Meifen Wang, Tingyi Du, Jiaolian Tang, Shuying Long, Juan Zhang, Jia Luo, Yue Pan, Junying Chen, Jing Ma, Xiaomei Liu, Mao Fan, Tiesong Zhang, Qiangming Sun,

Enterovirus A71 (EV-A71) inactivated vaccines have been widely inoculated among children in Kunming City after it was approved. However, there was a large-scale outbreak of Enteroviruses (EVs) infection in Kunming, 2018. The epidemiological characteristics of HFMD and EVs were analysed during 2008-2018, which are before and three years after EV-A71 ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):619-628]

Cited: 0 times

View full text PDF listing >>



Intensified antibody response elicited by boost suggests immune memory in individuals administered two doses of SARS-CoV-2 inactivated vaccine.

Yun Liao, Ying Zhang, Heng Zhao, Jing Pu, Zhimei Zhao, Dandan Li, Shengtao Fan, Li Yu, Xingli Xu, Lichun Wang, Guorun Jiang, Longding Liu, Qihan Li,

Neutralizing antibodies in the subjects of an inactivated SARS-CoV-2 vaccine clinical trial showed a decreasing trend over months. An investigation studying the third immunization suggested that the waning of neutralizing antibodies in individuals administered two doses of inactivated vaccine does not mean the disappearance of immunity. ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1112-1115]

Cited: 0 times

View full text PDF listing >>



A qualitative study of parental views of HPV vaccination in Ireland.

Stephanie Creed, Elaine Walsh, Tony Foley,

<h4>Background</h4>Despite significant evidence supporting the Human Papillomavirus (HPV) vaccine in the prevention of cervical cancer, uptake of this vaccine is below target in many countries. HPV uptake in Ireland has declined from 87% in 2014-15 to 51% in 2016-17 and currently remains suboptimal at 64.1% in 2017-18.<h4>Objectives</h4>This study aimed to ... Read more >>

Eur J Gen Pract (The European journal of general practice)
[2021, 27(1):1-9]

Cited: 0 times

View full text PDF listing >>



A practical method for evaluating the in vivo efficacy of EVA-71 vaccine using a hSCARB2 knock-in mouse model.

Yong Wu, Zhe Qu, Rui Xiong, Yanwei Yang, Susu Liu, Jianhui Nie, Chunnan Liang, Weijin Huang, Youchun Wang, Changfa Fan,

Hand-foot-and-mouth disease is a contagious disease common among children under 5 years old worldwide. It is caused by strains of enterovirus, especially EV-A71, which can lead to severe disease. Vaccines are the only way to fight this disease. Accordingly, it is necessary to establish an efficient and accurate methodology to ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1180-1190]

Cited: 0 times

View full text PDF listing >>



A novel oral rabies vaccine enhances the immunogenicity through increasing dendritic cells activation and germinal center formation by expressing U-OMP19 in a mouse model.

Jianqing Zhao, Yijing Zhang, Yixi Chen, Juntao Zhang, Jie Pei, Min Cui, Zhen F Fu, Ling Zhao, Ming Zhou,

Rabies remains a public health threat in most parts of the world. Dogs, especially stray dogs, are the main sources of rabies transmission in developing countries, while wild animals are primarily responsible for the spread of rabies in developed countries and play an emerging role in rabies transmission in developing ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):913-928]

Cited: 0 times

View full text PDF listing >>



High dose of vesicular stomatitis virus-vectored Ebola virus vaccine causes vesicular disease in swine without horizontal transmission.

Igor Morozov, Thomas P Monath, David A Meekins, Jessie D Trujillo, Sun-Young Sunwoo, Kinga Urbaniak, In Joong Kim, Sanjeev K Narayanan, Sabarish V Indran, Wenjun Ma, William C Wilson, Cassandra O'Connor, Sheri Dubey, Sean P Troth, Beth-Ann Coller, Richard Nichols, Brian K Martin, Heinz Feldmann, Juergen A Richt,

<b>ABSTRACT</b>The recent impact of Ebola virus disease (EVD) on public health in Africa clearly demonstrates the need for a safe and efficacious vaccine to control outbreaks and mitigate its threat to global health. ERVEBO® is an effective recombinant Vesicular Stomatitis Virus (VSV)-vectored Ebola virus vaccine (VSV-EBOV) that was approved by ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):651-663]

Cited: 0 times

View full text PDF listing >>



Serosurvey in BNT162b2 vaccine-elicited neutralizing antibodies against authentic B.1, B.1.1.7, B.1.351, B.1.525 and P.1 SARS-CoV-2 variants.

Alberto Zani, Francesca Caccuri, Serena Messali, Carlo Bonfanti, Arnaldo Caruso,

In this study, we show that BNT162b2 vaccine-elicited antibodies efficiently neutralize SARS-CoV-2 authentic viruses belonging to B.1, B.1.1.7, B.1.351, B.1.525 and P.1 lineages. Interestingly, the neutralization of B.1.1.7 and B.1.525 lineages was significantly higher, whereas the neutralization of B.1.351 and P.1 lineages was robust but significantly lower as compared to ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1241-1243]

Cited: 0 times

View full text PDF listing >>



Streptococcus Pneumoniae septic arthritis in adults in Bristol and Bath, United Kingdom, 2006-2018: a 13-year retrospective observational cohort study.

Catherine Hyams, Zahin Amin-Chowdhury, Norman K Fry, Paul North, Adam Finn, Andrew Judge, Shamez N Ladhani, O Martin Williams,

Few studies on adult pneumococcal septic arthritis are sufficiently large enough to assess both epidemiological trends following routine pneumococcal immunization and clinical disease. With major shifts in serotypes causing invasive pneumococcal disease (IPD), we wanted to determine the clinical phenotype of adult septic arthritis caused by <i>Streptococcus pneumoniae</i>. We conducted ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1369-1377]

Cited: 0 times

View full text PDF listing >>



Symptomatic SARS-CoV-2 infections after full schedule BNT162b2 vaccination in seropositive healthcare workers: a case series from a single institution.

Andreina Baj, Federica Novazzi, Angelo Genoni, Francesca Drago Ferrante, Stefano Taborelli, Beatrice Pini, Michele Partenope, Marilena Valli, Daniela Dalla Gasperina, Riccardo Capuano, Martina Prestia, Pietro Giorgio Spezia, Lorenzo Azzi, Daniele Focosi, Fabrizio Maggi,

We report 11 cases of SARS-CoV-2 infection in healthcare workers (HCW) <i>naïve</i> for COVID-19 and seropositive after the second dose of the BNT162b2 mRNA vaccine. Based on voluntary-based surveillance, they tested positive for different strains of SARS-CoV-2, as Spike gene sequencing showed. Five of them reported mild symptoms. Given the ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1254-1256]

Cited: 0 times

View full text PDF listing >>



Can algae contribute to the war with Covid-19?

Wen Yi Chia, Hanz Kok, Kit Wayne Chew, Sze Shin Low, Pau Loke Show,

The world at large is facing a new threat with the emergence of the Coronavirus Disease 2019 (COVID-19) pandemic. Though imperceptible by the naked eye, the medical, sociological and economical implications caused by this newly discovered virus have been and will continue to be a great impediment to our lives. ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1226-1237]

Cited: 0 times

View full text PDF listing >>



COVID-19 evolution during the pandemic - Implications of new SARS-CoV-2 variants on disease control and public health policies.

Cock van Oosterhout, Neil Hall, Hinh Ly, Kevin M Tyler,

Virulence (Virulence)
[2021, 12(1):507-508]

Cited: 20 times

View full text PDF listing >>



Tumor RNA-loaded nanoliposomes increases the anti-tumor immune response in colorectal cancer.

Dandong Dai, You Yin, Yuanbo Hu, Ying Lu, Hongbo Zou, GuangZhao Lu, Qianqian Wang, Jie Lian, Jie Gao, Xian Shen,

<h4>Purpose</h4>Tumor RNA vaccines can activate dendritic cells to generate systemic anti-tumor immune response. However, due to easily degraded of RNA, direct RNA vaccine is less effective. In this study, we optimized the method for preparing PEGylated liposom-polycationic DNA complex (LPD) nanoliposomes, increased encapsulate amount of total RNA derived from CT-26 ... Read more >>

Drug Deliv (Drug delivery)
[2021, 28(1):1548-1561]

Cited: 0 times

View full text PDF listing >>



The pattern of human papillomavirus infection and genotypes among Nigerian women from 1999 to 2019: a systematic review.

Anthony Uchenna Emeribe, Idris Nasir Abdullahi, Maisie Henrietta Etukudo, Idongesit Kokoabasi Isong, Anthony Ogbonna Emeribe, Justin Onyebuchi Nwofe, Chikodi Modesta Umeozuru, Buhari Isa Shuaib, Odunayo Rahmat Oyetola Ajagbe, Amos Dangana, Bibiana Nonye Egenti, Peter Elisha Ghamba,

<h4>Background</h4>There are no robust national prevalence of Human Papillomavirus (HPV) genotypes in Nigerian women despite the high burden of cervical cancer morbidity and mortality.<h4>The objective of study</h4>This study aims to determine the pooled prevalence and risk factors of genital HPV infection in Nigeria through a systemic review protocol.<h4>Methods</h4>Databases including PubMed, ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):944-959]

Cited: 0 times

View full text PDF listing >>



Pneumococcal surface adhesion A protein (PsaA) interacts with human Annexin A2 on airway epithelial cells.

Yoonsung Hu, Nogi Park, Keun Seok Seo, Joo Youn Park, Radha P Somarathne, Alicia K Olivier, Nicholas C Fitzkee, Justin A Thornton,

<i>Streptococcus pneumoniae</i> (pneumococcus) is a normal colonizer of the human nasopharynx capable of causing serious invasive disease. Since colonization of the nasopharynx is a prerequisite for progression to invasive diseases, the development of future protein-based vaccines requires an understanding of the intimate interaction of bacterial adhesins with host receptors. In ... Read more >>

Virulence (Virulence)
[2021, 12(1):1841-1854]

Cited: 0 times

View full text PDF listing >>



Naturally circulating pertactin-deficient Bordetella pertussis strains induce distinct gene expression and inflammatory signatures in human dendritic cells.

Michiel M Kroes, Alberto Miranda-Bedate, Elise S Hovingh, Ronald Jacobi, Corrie Schot, Elder Pupo, René H M Raeven, Arno A J van der Ark, Jos P M van Putten, Jelle de Wit, Rob Mariman, Elena Pinelli,

Respiratory infections caused by <i>Bordetella pertussis</i> are reemerging despite high pertussis vaccination coverage. Since the introduction of the acellular pertussis vaccine in the late twentieth century, circulating <i>B. pertussis</i> strains increasingly lack expression of the vaccine component pertactin (Prn). In some countries, up to 90% of the circulating <i>B. pertussis</i> ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):1358-1368]

Cited: 0 times

View full text PDF listing >>



Department of Error.

Lancet (Lancet (London, England))
[2021, 396(10267):1978]

Cited: 0 times

View full text PDF listing >>



Mitigating the threat of emerging infectious diseases; a coevolutionary perspective.

Cock Van Oosterhout,

Virulence (Virulence)
[2021, 12(1):1288-1295]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.117 s