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Trigeminal Neuralgia

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Bilateral calcaneal insufficiency fractures due to chronic carbamazepine use for trigeminal neuralgia: A case report.

O Kaya, C Hurel, G Gumussuyu, O Kose,

Stress fractures of calcaneus are uncommon cause of heel pain. Stress fractures could be seen in risc groups such as metabolic diseases/medications causing poor bone quality and exposing repetitive microtrauma. Anti-epileptic drug (AED) use is related with poor bone quality and increased fracture risc. Although carbamazepine-induced stress fracture is a ... Read more >>

Niger J Clin Pract (Nigerian journal of clinical practice)
[2020, 23(4):574-576]

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The applicability and efficacy of magnetic resonance-guided high intensity focused ultrasound system in the treatment of primary trigeminal neuralgia.

Yaping Ma, Grace Hsu, Fugui Zhang,

Primary trigeminal neuralgia is a common clinical refractory neuralgia characterized by an onset of excruciating pain that can severely affect patients' quality of life. Long-term suffering from this pain may lead to depression, anxiety, and suicide. Current treatments, however, are associated with high recurrent rates and severe complications. We hypothesize ... Read more >>

Med. Hypotheses (Medical hypotheses)
[2020, 139:109688]

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Percutaneous Microcompression for Idiopathic Trigeminal Neuralgia: curative effects and complications

yi ma, Yan-feng Li, Hai-tao Huang, Bin Wang, Quan-cai Wang,

<title>Abstract</title> <p> Background. We aimed to present the immediate and long term effect of percutaneous balloon compression (PBC) for idiopathic trigeminal neuralgia (ITN). Methods. ITN patients who underwent PBC for the first time in the past seven years were enrolled. Base line data and immediate postoperative outcomes were ... Read more >>

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Letter to the Editor Regarding "Possible Prognostic Role of Magnetic Resonance Imaging Findings in Patients with Trigeminal Neuralgia and Multiple Sclerosis who Underwent Percutaneous Balloon Compression: Report of Our Series and Literature Review".

Mario Francesco Fraioli, Gianluca Scalia, Francesco Giuseppe Garaci, Chiara Fraioli, Pierpaolo Lunardi, Giuseppe Emmanuele Umana,

World Neurosurg (World neurosurgery)
[2020, 136:433-434]

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In Reply to the Letter to the Editor Regarding "Possible Prognostic Role of Magnetic Resonance Imaging Findings in Patients with Trigeminal Neuralgia and Multiple Sclerosis Who Underwent Percutaneous Balloon Compression: Report of Our Series and Literature Review".

Nicola Montano, Eleonora Ioannoni, Alessandro Rapisarda, Alessandro Olivi,

World Neurosurg (World neurosurgery)
[2020, 136:435-436]

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Trigeminal neuralgia linked to demyelination in multiple sclerosis.

Heather Wood,

Nat Rev Neurol (Nature reviews. Neurology)
[2020, :]

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Peripheral nerve field stimulation in medically refractory trigeminal neuralgia attributed to multiple sclerosis.

Johann Klein, Timo Siepmann, Gabriele Schackert, Tjalf Ziemssen, Tareq A Juratli,

OBJECTIVE:Case reports and small patient series have suggested peripheral nerve field stimulation (PNFS) as a treatment for refractory trigeminal neuralgia attributed to multiple sclerosis (MS). Here, the authors aimed to assess the effects of this technique on long-term pain severity. METHODS:Data were prospectively collected on patients with refractory trigeminal neuralgia ... Read more >>

J. Neurosurg. (Journal of neurosurgery)
[2020, :1-7]

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Trigeminal neuralgia in multiple sclerosis: Prevalence and association with demyelination.

Sini M Laakso, Oskari Hekali, Goran Kurdo, Juha Martola, Tiina Sairanen, Sari Atula,

OBJECTIVES:The association of trigeminal neuralgia (TN) with multiple sclerosis (MS) is still widely unaddressed in larger, systematical clinical series. In this study, a cohort of Finnish MS patients was assessed regarding the incidence and prevalence of TN, as well as the presence of demyelinating lesions near the trigeminal ganglion, thus ... Read more >>

Acta Neurol. Scand. (Acta neurologica Scandinavica)
[2020, :]

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[Functional stereotactic radiosurgery: Indications and perspectives].

G Dupic, J Biau, J J Lemaire, C Ortholan, P Clavelou, M Lapeyre, P Colin, T Khalil,

Stereotactic radiosurgery (SRS) is a non-invasive technique that enables to create brain focal lesions with a high precision and localization. Thus, functional brain disorders can be treated by SRS in case of pharmacoresistance or inoperability. To date, treatment of trigeminal neuralgia is the most described and known indication. Other indications ... Read more >>

Cancer Radiother (Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique)
[2020, :]

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Microvascular decompression: is routine postoperative CT imaging necessary?

Gökce Hatipoglu Majernik, Shadi Al-Afif, Hans E Heissler, Luisa Cassini Ascencao, Joachim K Krauss,

BACKGROUND:Postoperative head CT imaging is routinely performed for detection of postoperative complications following intracranial procedures. However, it remains unclear whether with regard to radiation exposure, costs, and possibly lack of consequences this practice is truly justified in various operative procedures. The objective of this study was to analyze whether routine ... Read more >>

Acta Neurochir (Wien) (Acta neurochirurgica)
[2020, :]

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Subtemporal Transtentorial Approach in Mesencephalic and Perimesencephalic Lesions in Children-A Series of 20 Patients.

Pietro Spennato, Carmela Chiaramonte, Carmela Russo, Nicola Onorini, Giuseppe Mirone, Federica Mazio, Giuliana Di Martino, Raffaele Stefano Parlato, Giuseppe Cinalli,

BACKGROUND:Midbrain and surrounding areas are among the most difficult regions to surgically approach in neurosurgery. The subtemporal approach is a well-known neurosurgical approach that is rarely described in children. OBJECTIVE:To assess the feasibility, advantages, and disadvantages of subtemporal approach in children. METHODS:A total of 20 pediatric patients with intra-axial tumors ... Read more >>

Oper Neurosurg (Hagerstown) (Operative neurosurgery (Hagerstown, Md.))
[2020, 18(4):349-362]

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A Novel Technical Refinement of Microvascular Decompression: Pain Relief and Complication Rate in a Consecutive Series of Patients With Trigeminal Neuralgia.

Francesco Tomasello, Antonino Germanò, Angelo Lavano, Alberto Romano, Daniele Cafarella, Nicola Gorgoglione, Domenico La Torre,

BACKGROUND:Microvascular decompression (MVD) represents a milestone for the treatment of trigeminal neuralgia (TN). Nevertheless, several complications still occur and may negatively affect the outcome. We recently proposed some technical nuances for complication avoidance related to MVD. OBJECTIVE:To verify the efficacy of the proposed refinement of the standard MVD technique in ... Read more >>

Oper Neurosurg (Hagerstown) (Operative neurosurgery (Hagerstown, Md.))
[2020, :]

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CGRP Plasma Levels Decrease in Classical Trigeminal Neuralgia Patients Treated with Botulinum Toxin Type A: A Pilot Study.

Yi Zhang, Yajun Lian, Haifeng Zhang, Nanchang Xie, Yuan Chen,

OBJECTIVE:The aim of this study was to investigate the changes of calcitonin gene-related peptide (CGRP) plasma levels in patients with classical trigeminal neuralgia (TN) and if plasma CGRP concentrations could be used to predict the response to botulinum toxin type A (BTX-A). METHODS:Forty-seven patients with classical TN were recruited and ... Read more >>

Pain Med (Pain medicine (Malden, Mass.))
[2020, :]

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Clinical Analysis of Patients with Ipsilateral Coexistence of Hemifacial Spasm and Trigeminal Neuralgia.

Jiayu Liu, Chunping Zhu, Ruen Liu, Bo Liu, Jingru Zhou, Cungang Fan, Feng Jiao, Dongliang Wang, Gang Wu, Yongan Jiang,

OBJECTIVE:To analyze the clinical data of patients with ipsilateral coexistence of hemifacial spasm (HFS) and trigeminal neuralgia (TN) and their treatment by microvascular decompression (MVD). METHODS:We retrospectively analyzed the clinical data, imaging examination, offending vessels, surgical methods and efficacy in 40 patients with ipsilateral coexistence of HFS and TN from ... Read more >>

World Neurosurg (World neurosurgery)
[2020, :]

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Percutaneous Trigeminal Stimulation for Intractable Facial Pain: A Case Series.

Pavlos Texakalidis, Muhibullah S Tora, J Tanner McMahon, Alexander Greven, Casey L Anthony, Purva Nagarajan, Melissa Campbell, Nicholas M Boulis,

BACKGROUND:Facial pain syndromes can be refractory to medical management and often need neurosurgical interventions. Neuromodulation techniques, including percutaneous trigeminal ganglion (TG) stimulation, are reversible and have emerged as alternative treatment options for intractable facial pain. OBJECTIVE:To report the complication rates and analgesic effects associated with TG stimulation and identify potential ... Read more >>

Neurosurgery (Neurosurgery)
[2020, :]

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Effects of palmatine on BDNF/TrkB-mediated trigeminal neuralgia.

Lijuan Liu, Lingkun He, Cancan Yin, Ruoyu Huang, Wenhao Shen, Huixiang Ge, Mengyun Sun, Shujuan Li, Yun Gao, Wei Xiong,

Trigeminal neuralgia (TN), a sudden, needle-like pain in the distribution area of the trigeminal nerve, can seriously affect the physical and mental health of patients. In chronic pain conditions including TN, increased levels of brain-derived neurotrophic factor (BDNF) may enhance pain transmission. This study compares the effect of palmatine administration ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):4998]

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Preliminary study of calcium homeostasis modulator 1 involved in trigeminal neuralgia

Xuebin Yan, Yi Liu, Keji Li, Dong Huang,

<title>Abstract</title> <p> Background: The aim of this study was to observe the changes in the expression of calcium homeostasis modulator 1 (CALHM1) in the trigeminal nucleus of the trigeminal neuralgia (TN) rats with the infraorbital nerve-chronic constrictive nerve injury (ION-CCI) and to explore the role of CALHM1 in ... Read more >>

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Trigeminal neuralgia due to compression of primitive trigeminal artery variant, usefulness of fusion images of MRI CISS and CT angiography : a case report.

Kenshi Sano, Atsushi Kuge, Rei Kondo, Tetsu Yamaki, Yu Shimokawa, Shinjiro Saito, Yukihiko Sonoda,

A 65 year-old man presented with a 2-year history of left paroxysmal facial pain in the second division of trigeminal nerve. We diagnosed left trigeminal neuralgia (TN) due to primitive trigeminal artery variant (PTAv) using MRI constructive interference in steady state (CISS) and CT angiography (CTA). Microvascular decompression surgery disclosed ... Read more >>

World Neurosurg (World neurosurgery)
[2020, :]

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Diagnostic and Therapeutic Errors in Classical Trigeminal Neuralgia: a Multicenter Survey

Fabio Antonaci, Sebastiano Arceri, Martin Rakusa, Dimos Mitsikostas, Ivan Milanov, Vasil Todorov, Matteo Ramusino, Alfredo Costa,

<title>Abstract</title> <p> Background Classical Trigeminal neuralgia (CTN) is a severe, disabling form of painful cranial neuropathy. Even though CTN has a typical clinical picture, diagnosis it is often missed or delayed in clinical practice. This study was carried over to investigate the occurrence of diagnostic and therapeutic errors ... Read more >>

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Effects of Supraorbital Foramen Variations on the Treatment Efficacy of Radiofrequency Therapy for V1 Trigeminal Neuralgia: A Retrospective Study.

Keyue Xie, Songlei Liu, Bing Huang, Ming Yao,

Background:Primary V1 trigeminal neuralgia is a common refractory neuralgia in clinical practice, lacking effective treatments. Radiofrequency therapy has certain treatment efficacy, but its long-term efficacy remained poor and the disease might relapse. Objective:To compare the effects of different types of supraorbital foramen variations on the treatment efficacy of radiofrequency therapy ... Read more >>

Pain Res Manag (Pain research & management)
[2020, 2020:8142489]

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Biplane Fluoroscopic-Guided Balloon Rhizotomy for Trigeminal Neuralgia: A Technical Note.

Awais Z Vance, Tarek Y El Ahmadieh, Zachary Christian, Salah G Aoun, Samuel L Barnett, Jonathan A White,

BACKGROUND:The classic percutaneous technique used to cannulate the foramen ovale for the treatment of trigeminal neuralgia can place important anatomic structures, such as the distal cervical internal carotid artery, at risk. OBJECTIVE:To use fixed anatomic landmarks to safely and reliably locate the foramen ovale on anteroposterior (AP) fluoroscopy. METHODS:Locating the ... Read more >>

Oper Neurosurg (Hagerstown) (Operative neurosurgery (Hagerstown, Md.))
[2020, 18(3):295-301]

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Palmatine alleviates hyperalgesia by inhibiting the expression of calcitonin gene-related peptide in the trigeminal ganglion of rats with chronic constriction injury of the infraorbital nerve.

L He, L Liu, S Guan, X Zheng, H Ge, C Yin, Y Shen, M Tan, C Wang, Y Gao, W Xiong,

Trigeminal neuralgia is one of the most common of the neuropathic pains, and it can seriously influence patients' quality of life. Calcitonin gene-related peptide (CGRP) is a type of nociceptive neurotransmitter that is expressed in neurons of the trigeminal ganglion and plays a major part in transmitting pain. The rat ... Read more >>

Br J Oral Maxillofac Surg (The British journal of oral & maxillofacial surgery)
[2020, :]

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Craniofacial Peripheral Nerve Stimulation: Analysis of a Single Institution Series.

Tessa A Harland, Claudia Zbrzeski, Marisa DiMarzio, Olga Khazen, Michael D Staudt, Julie G Pilitsis,

OBJECTIVE:Objective real-world experience with peripheral nerve stimulation (PNS) is limited. Furthermore, the lack of robust outcome metrics, long-term follow-up and data comparing responders and nonresponders limit the refinement of selection criteria to better identify patients likely to benefit from PNS. MATERIALS AND METHODS:We retrospectively analyzed 22 patients with craniofacial pain ... Read more >>

Neuromodulation (Neuromodulation : journal of the International Neuromodulation Society)
[2020, :]

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Long-Term Efficacy and Complications of Radiofrequency Thermocoagulation at Different Temperatures for the Treatment of Trigeminal Neuralgia.

Tao Hong, Yuanyuan Ding, Peng Yao,

Trigeminal neuralgia (TN) is a common neuropathic pain that seriously affects the daily life of patients. Many invasive treatments are currently available for patients who respond poorly to oral carbamazepine or oxcarbazepine. Among them, radiofrequency (RF) treatment is a viable option with reliable initial and long-term clinical efficacy. The long-term ... Read more >>

Biochem Res Int (Biochemistry research international)
[2020, 2020:3854284]

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Oxcarbazepine for trigeminal neuralgia may induce lower extremity weakness: A case report.

Hyun-Gul Song, Francis Sahngun Nahm,

BACKGROUND:Although few studies have reported hyponatremia due to carbamazepine or oxcarbazepine in patients with epilepsy, no study has investigated cases of carbamazepine- or oxcarbazepine-induced hyponatremia or unsteady gait in patients with neuropathic pain. Herein, we report a case of oxcarbazepine-induced lower leg weakness in a patient with trigeminal neuralgia and ... Read more >>

World J Clin Cases (World journal of clinical cases)
[2020, 8(5):922-927]

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