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Traumatic Peripheral Nerve Lesions

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Contribution of ultrasonography in evaluating traumatic lesions of the peripheral nerves.

Gregor Omejec, Simon Podnar,

OBJECTIVE:To assess the indications for and utility of diagnostic ultrasonography (US) in a series of consecutive patients with suspected traumatic peripheral nerve lesions (TPNL). METHODS:We retrospectively reviewed the electronic medical records of consecutive patients referred from February 2013 to May 2018 to our US laboratory. All included patients were examined ... Read more >>

Neurophysiol Clin (Neurophysiologie clinique = Clinical neurophysiology)
[2020, :]

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Acute Complete Foot Drop Caused by Intraneural Ganglion Cyst without a Prior Traumatic Event.

Stavros Stamiris, Dimitrios Stamiris, Athanasios Sarridimitriou, Elissavet Anestiadou, Christos Karampalis, Vasileios Vrangalas,

Intraneural ganglion cysts are benign soft-tissue masses located in the epineurium of peripheral nerves. They originate from nearby joint connections via articular branches. Traumatic events seem to play a role in their pathogenesis as well. Clinical manifestations include pain over the area of the cyst, palpable tender mass, hypoesthesia, and ... Read more >>

Case Rep Orthop (Case reports in orthopedics)
[2020, 2020:1904595]

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[Neuromuscular complications of fractures of the extremities, part 2 : Nerve injuries and iatrogenic damage].

T Neubauer, J Brand, A Hartmann,

Lesions of peripheral nerves substantially influence the long-term prognosis and functional outcome. Approximately 70% of peripheral nerval lesions are associated with vascular injuries and occur more frequently with certain fractures and osteosynthesis types. The prognosis and treatment depend on the severity of the injury and the presence of axonal lesions, ... Read more >>

Unfallchirurg (Der Unfallchirurg)
[2020, 123(3):225-237]

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Fast-tracking regenerative medicine for traumatic brain injury.

Brooke Bonsack, Matt Heyck, Chase Kingsbury, Blaise Cozene, Nadia Sadanandan, Jea-Young Lee, Cesar V Borlongan,

Traumatic brain injury remains a global health crisis that spans all demographics, yet there exist limited treatment options that may effectively curtail its lingering symptoms. Traumatic brain injury pathology entails a progression from primary injury to inflammation-mediated secondary cell death. Sequestering this inflammation as a means of ameliorating the greater ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(7):1179-1190]

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Post-amputation neuroma of radial nerve in a patient with ephitelioid sarcoma: case report and literature review.

Fabio Sandomenico, Antonio Corvino, Sergio Venanzio Setola, Igino Simonetti, Mauro Porcaro, Piero Trovato, Orlando Catalano, Antonella Petrillo,

Neuroma, also known as traumatic neuroma or amputation neuroma or stump neuroma, is a focal non neoplastic area of proliferative hyperplastic reaction secondary to peripheral nerve damage that commonly occurs after a focal trauma (acute or chronic) or surgery, such as amputation or partial transection. Neuromas are more commonly located ... Read more >>

Acta Biomed (Acta bio-medica : Atenei Parmensis)
[2020, 91(1):122-127]

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Electrical stimulation and denervated muscles after spinal cord injury.

Subhalakshmi Chandrasekaran, John Davis, Ines Bersch, Gary Goldberg, Ashraf S Gorgey,

Spinal cord injury (SCI) population with injury below T10 or injury to the cauda equina region is characterized by denervated muscles, extensive muscle atrophy, infiltration of intramuscular fat and formation of fibrous tissue. These morphological changes may put individuals with SCI at higher risk for developing other diseases such as ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(8):1397-1407]

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Interference with SRF expression in skeletal muscles reduces peripheral nerve regeneration in mice.

Renate Wanner, Bernd Knöll,

Traumatic injury of peripheral nerves typically also damages nerve surrounding tissue including muscles. Hence, molecular and cellular interactions of neighboring damaged tissues might be decisive for successful axonal regeneration of injured nerves. So far, the contribution of muscles and muscle-derived molecules to peripheral nerve regeneration has only poorly been studied. ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):5281]

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Identification and Management of Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury.

Rui-Zhe Zheng, Zhong-Qi Lei, Run-Ze Yang, Guo-Hui Huang, Guang-Ming Zhang,

Paroxysmal sympathetic hyperactivity (PSH) has predominantly been described after traumatic brain injury (TBI), which is associated with hyperthermia, hypertension, tachycardia, tachypnea, diaphoresis, dystonia (hypertonia or spasticity), and even motor features such as extensor/flexion posturing. Despite the pathophysiology of PSH not being completely understood, most researchers gradually agree that PSH is ... Read more >>

Front Neurol (Frontiers in Neurology)
[2020, 11:81]

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Management of Spasticity After Traumatic Brain Injury in Children.

Johannes M N Enslin, Ursula K Rohlwink, Anthony Figaji,

Traumatic brain injury is a common cause of disability worldwide. In fact, trauma is the second most common cause of death and disability, still today. Traumatic brain injury affects nearly 475 000 children in the United States alone. Globally it is estimated that nearly 2 million people are affected by ... Read more >>

Front Neurol (Frontiers in neurology)
[2020, 11:126]

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The Neuroprotective and Biomarker Potential of PACAP in Human Traumatic Brain Injury.

Denes Toth, Andrea Tamas, Dora Reglodi,

Traumatic brain injury remains a growing public health concern and represents the greatest contributor to death and disability globally among all trauma-related injuries. There are limited clinical data regarding biomarkers in the diagnosis and outcome prediction of TBI. The lack of real effective treatment for recovery calls for research of ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(3):]

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Improved mouse sciatic nerve regeneration following lymphocyte cell therapy.

André Luis Bombeiro, Bruno Henrique de Melo Lima, Amanda Pires Bonfanti, Alexandre Leite Rodrigues de Oliveira,

Traumatic injury to the peripheral nervous system (PNS) is the most common cause of acquired nerve damage and impairs the quality of life of patients. The success of nerve regeneration depends on distal stump degeneration, tissue clearance and remodeling, processes in which the immune system participates. We previously reported improved ... Read more >>

Mol. Immunol. (Molecular immunology)
[2020, 121:81-91]

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Cap-Assisted Endoscopic Mucosal Resection of an Incidental Rectal Traumatic Neuroma.

Elias Estifan, Varun Patel, Matthew Grossman,

A traumatic neuroma is a well-known complication after acute trauma to a peripheral nerve; the nerve tries to re-establish continuity by an orderly growth of axons from the peripheral to distal stump through the proliferation of Schwann cells. However, this process is not always perfect, and aberrant repair gives rise ... Read more >>

Case Rep Gastrointest Med (Case reports in gastrointestinal medicine)
[2019, 2019:8328456]

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Ultrasonography: the third eye of hand surgeons.

Esther Vögelin,

High-resolution ultrasonography is an important tool used for the diagnosis and management of inflammatory arthritis of the hand and wrist. This imaging modality has also proven its utility in the evaluation of traumatic lesions of tendons, nerves, annular pulleys, ligaments, and carpal and digital injuries and for detecting foreign bodies ... Read more >>

J Hand Surg Eur Vol (The Journal of hand surgery, European volume)
[2020, 45(3):219-225]

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Brainstem dysfunction in critically ill patients.

Sarah Benghanem, Aurélien Mazeraud, Eric Azabou, Vibol Chhor, Cassia Righy Shinotsuka, Jan Claassen, Benjamin Rohaut, Tarek Sharshar,

The brainstem conveys sensory and motor inputs between the spinal cord and the brain, and contains nuclei of the cranial nerves. It controls the sleep-wake cycle and vital functions via the ascending reticular activating system and the autonomic nuclei, respectively. Brainstem dysfunction may lead to sensory and motor deficits, cranial ... Read more >>

Crit Care (Critical Care)
[2020, 24(1):5]

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[Traumatic peripheral nerve lesions : Diagnosis and treatment].

M Schneider, G Antoniadis,

Traumatic peripheral nerve lesions affect patients of all age groups. They are associated with functional deficits that have severe consequences for affected patients and prolonged or permanent inability to work has socioeconomic relevance. In order to improve prognoses and achieve the best possible outcome an early diagnosis and competent knowledge ... Read more >>

Chirurg (Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen)
[2019, 90(11):941-954]

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A case of a facial nerve venous malformation presenting with crocodile tear syndrome.

Dinesh Rao, Peter Fiester, Gazanfar Rahmathulla, Rafaat Makary, Daryoush Tavanaiepour,

Background:Crocodile tears syndrome, also known as Bogorad syndrome, is characterized by lacrimation secondary to olfactory and gustatory stimuli and mastication. Crocodile tear syndrome is typically encountered as an uncommon complication of Bell's palsy and usually occurs during the recovery phase of the disease course. Case Description:We present a case of ... Read more >>

Surg Neurol Int (Surgical neurology international)
[2020, 11:3]

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18 F-FDG uptake in denervated muscles of patients with peripheral nerve injury.

Ji Soo Choi, Han Gil Seo, Byung-Mo Oh, Hongyoon Choi, Gi Jeong Cheon, Shi-Uk Lee, Seung Hak Lee,

OBJECTIVE:We aimed to investigate the clinical significance of increased uptake in 18 F-fluorodeoxyglucose positron emission tomography in patients with peripheral nerve lesions. METHODS:We selected patients with unilateral peripheral nerve lesions confirmed with electromyography who had undergone 18 F-fluorodeoxyglucose positron emission tomography covering the lesions. In the denervated muscles and their ... Read more >>

Ann Clin Transl Neurol (Annals of clinical and translational neurology)
[2019, 6(11):2175-2185]

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Transcarotid repair of carotid artery pseudoaneurysm after carotid artery endarterectomy with tandem distal internal carotid artery stenosis.

L Graham Rucker, Mark J Broering, Brian A Kuhn, Aaron Kulwicki, Matthew H Recht, Patrick E Muck,

Pseudoaneurysm development after carotid endarterectomy is a rare occurrence. Even rarer is pseudoaneurysm formation associated with a distal carotid artery stenosis. We report the case of stent grafting of a carotid artery pseudoaneurysm and tandem high-grade distal stenosis through a transcarotid approach with active flow reversal. No reported cases of ... Read more >>

J Vasc Surg Cases Innov Tech (Journal of vascular surgery cases and innovative techniques)
[2020, 6(1):136-139]

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Isolated Nerve Grafting for a Young Patient with a Complete Common Peroneal Nerve Palsy Following a Traumatic Knee Dislocation: A case report.

Shintaro Mukohara, Atsuyuki Inui, Yutaka Mifune, Hanako Nishimoto, Takeshi Kataoka, Takashi Kurosawa, Kohei Yamaura, Ryosuke Kuroda,

BACKGROUND:Common peroneal nerve (CPN) injury following a knee dislocation is a serious problem, and an optimal treatment is yet to be established. We report a case of complete CPN palsy following a knee dislocation treated with sural nerve grafting. CASE:A 19-year-old man suffered a knee injury during a hurdle race. ... Read more >>

Kobe J Med Sci (The Kobe journal of medical sciences)
[2020, 65(3):E110-E113]

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Neural crest derived stem cells from dental pulp and tooth-associated stem cells for peripheral nerve regeneration.

Alessandra Pisciotta, Laura Bertoni, Antonio Vallarola, Giulia Bertani, Daniela Mecugni, Gianluca Carnevale,

The peripheral nerve injuries, representing some of the most common types of traumatic lesions affecting the nervous system, are highly invalidating for the patients besides being a huge social burden. Although peripheral nervous system owns a higher regenerative capacity than does central nervous system, mostly depending on Schwann cells intervention ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(3):373-381]

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Tingling hand: magnetic resonance imaging of median nerve pathologies within the carpal tunnel.

Ashwini Kumari, Sapna Singh, Anju Garg, Anjali Prakash, Sumit Sural,

Compressive neuropathy of the median nerve at the level of the carpal tunnel, known as carpal tunnel syndrome, is the most common entrapment neuropathy, affecting about 0.1-1% of the general population. Magnetic resonance reliably imaged the flexor retinaculum and carpal bones and thus defined the borders of the carpal tunnel. ... Read more >>

Pol J Radiol (Polish journal of radiology)
[2019, 84:e484-e490]

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Chronic neuropathic pain after traumatic peripheral nerve injuries in the upper extremity: prevalence, demographic and surgical determinants, impact on health and on pain medication.

Adriana Miclescu, Antje Straatmann, Panagiota Gkatziani, Stephen Butler, Rolf Karlsten, Torsten Gordh,

Background and aims Aside from the long term side effects of a nerve injury in the upper extremity with devastating consequences there is often the problem of chronic neuropathic pain. The studies concerning the prevalence of persistent pain of neuropathic origin after peripheral nerve injuries are sparse. The prevalence and ... Read more >>

Scand J Pain (Scandinavian journal of pain)
[2019, 20(1):95-108]

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A radiologic review of hoarse voice from anatomic and neurologic perspectives.

Simone Montoya, Anthony Portanova, Alok A Bhatt,

The differential diagnosis for hoarseness is extensive and includes a multitude of etiologies that span a large geographic area from the brainstem to the mediastinum. Therefore, localizing a causative lesion can be extremely difficult for clinicians and radiologists alike. In this review, we will first discuss the normal anatomy of ... Read more >>

Insights Imaging (Insights into imaging)
[2019, 10(1):108]

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Cranio-Orbital and Orbitocranial Approaches to Orbital and Intracranial Disease: Eye-Opening Approaches for Neurosurgeons.

Hussam Abou-Al-Shaar, Khaled M Krisht, Michael A Cohen, Abdullah M Abunimer, Jayson A Neil, Michael Karsy, Gmaan Alzhrani, William T Couldwell,

Orbital approaches for targeting intracranial, orbital, and infratemporal disease have evolved over the years in an effort to discover safe, reliable, effective, and cosmetically satisfying surgical corridors. The surgical goals of these approaches balance important factors such as proximity of the lesion to the optic nerve, the degree of anticipated ... Read more >>

Front Surg (Frontiers in surgery)
[2020, 7:1]

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Neurofilaments: The C-Reactive Protein of Neurology.

Kate L Lambertsen, Catarina B Soares, David Gaist, Helle H Nielsen,

Neurofilaments (NFs) are quickly becoming the biomarkers of choice in the field of neurology, suggesting their use as an unspecific screening marker, much like the use of elevated plasma C-reactive protein (CRP) in other fields. With sensitive techniques being readily available, evidence is growing regarding the diagnostic and prognostic value ... Read more >>

Brain Sci (Brain sciences)
[2020, 10(1):]

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