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Transposition of the Great Arteries

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Arterial-level repair of transposition of great arteries without coronary artery transfer.

Ahmed A Elassal, Gaser A Abdelmohsen, Mohamed S Elhudairy, Osman O Al-Radi,

Hypoplastic ascending aorta and interrupted aortic arch (IAA) are rarely associated with dextro-transposition of the great arteries (D-TGA). Severe hypoplastic ascending aorta may preclude coronary artery transfer making arterial switch operation problematic. We report a case of D-TGA with a large subpulmonic ventricular septal defect, IAA, and hypoplastic ascending aorta ... Read more >>

J Card Surg (Journal of cardiac surgery)
[2020, :]

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IgA Vasculitis Triggered by Infective Endocarditis of Pulmonary Artery with Congenitally Corrected Transposition of the Great Arteries.

Midori Akagi, Nozomi Iwanaga, Yuichi Torisu, Hisayuki Fujita, Chieko Kawahara, Yoshiro Horai, Yasumori Izumi, Atsushi Kawakami,

A man in his 40s with a history of congenitally corrected transposition of the great arteries (CCTGA) and closure of ventricular septal defect was referred to our hospital with purpura and hematuria. Presence of purpura, renal damage, and pathological findings on skin biopsy led to the diagnosis of IgA vasculitis ... Read more >>

Int Heart J (International heart journal)
[2020, :]

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Atrial tachycardia eliminated at the ventricular side in patients with congenitally corrected transposition of the great arteries: Electrophysiological findings and anatomical concerns.

Chen-Xi Jiang, De-Yong Long, Xin Du, Cai-Hua Sang, Yan Yao, Meng-Meng Li, Ri-Bo Tang, Song-Nan Li, Song-Nan Wen, Rong Bai, Jian-Zeng Dong, Chang-Sheng Ma,

BACKGROUND:The unique malformation of congenitally corrected transposition of the great arteries (cc-TGA) makes the pulmonary outflow tract (POT) a possible origin of atrial tachycardia (AT). OBJECTIVE:The purpose of this study was to investigate the mapping characteristics of ATs successfully ablated at the POT in cc-TGA patients. METHODS:Cc-TGA patients with AT ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, :]

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Radiofrequency ablation for the pre-excitation syndrome of functionally corrected transposition of great arteries.

Jun Li, Haixiong Wang, Yanqing Guo,

We reported a 57-year-old female patient who had functionally corrected transposition of the great arteries, severe tricuspid insufficiency, enlarged left atrium and functional right ventricle, which were successfully performed radiofrequency ablation. ... Read more >>

J Card Surg (Journal of cardiac surgery)
[2020, :]

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Complete closure of the ductus arteriosus in the foetus with transposition of the great arteries.

Agnieszka Grzyb, Adam Koleśnik, Dariusz Gruszfeld, Joanna Szymkiewicz-Dangel,

Prenatal restriction of the ductus arteriosus can manifest as persistent pulmonary hypertension in the newborn, especially dangerous with the transposition of the great arteries. Its aetiology has long been related to maternal intake of non-steroidal anti-inflammatory drugs; however, some other substances, including polyphenols, may have similar properties. We describe a ... Read more >>

Cardiol Young (Cardiology in the young)
[2020, :1-3]

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Late Presentation of a Congenitally Corrected Transposition of Great Arteries and Hemodynamically Balanced Ventricles Associated with a Large Ventricular Septal Defect and Severe Pulmonary Stenosis: A Case Report and a Multi-Imaging Approach.

Khaled Elenizi, Rasha Alharthi, Anthony Matta, Abdulrahman Aljuayli, Michel Galinier,

BACKGROUND Congenitally corrected transposition of great arteries (ccTGA) represents a distinct rare group of congenital heart diseases. Survival of unoperated ccTGA in the presence of large ventricular septal defect (VSD) is exceptional. Furthermore, late presentation of such patients in the absence of severe pulmonary hypertension or severe systemic right ventricle ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e920822]

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Congenitally corrected transposition of the great arteries, coronary anomaly and transplant.

Diana Isabel Katekaru-Tokeshi, Moisés Jiménez-Santos,

Rev Esp Cardiol (Engl Ed) (Revista espanola de cardiologia (English ed.))
[2020, :]

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Serial changes of tricuspid regurgitation after anatomic repair for congenitally corrected transposition.

Tsubasa Furuya, Takaya Hoashi, Masatoshi Shimada, Kenta Imai, Motoki Komori, Kenichi Kurosaki, Kazuto Fujimoto, Hajime Ichikawa,

OBJECTIVES:The aim of this study was to reveal the serial changes in tricuspid regurgitation (TR) after anatomic repair for congenitally corrected transposition of great arteries. METHODS:Between 1995 and 2018, 48 patients underwent anatomic repair (atrial/arterial switch in 14 patients, atrial switch and Rastelli in 34 patients). The mean age and ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2020, :]

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Transposition of great arteries with coarctation of aorta: a rare association demonstrated on dual source CT.

Vineeta Ojha, Surya Pratap Singh, Kartik Ganga Ponnuswamy, Priya Jagia,

Acta Cardiol (Acta cardiologica)
[2020, :1-2]

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Venoarterial extracorporeal membrane oxygenation in heart surgery post-operative pediatric patients: A retrospective study at Christus Muguerza Hospital, Monterrey, Mexico.

Gerardo Vargas-Camacho, Verónica Contreras-Cepeda, Rene Gómez-Gutierrez, Guillermo Quezada-Valenzuela, Adriana Nieto-Sanjuanero, Jesús Santos-Guzmán, Francisco González-Salazar,

Objectives:Extracorporeal membrane oxygenation is a life support procedure developed to offer cardiorespiratory support when conventional therapies have failed. The purpose of this study is to describe the findings during the first years using venoarterial extracorporeal membrane oxygenation in pediatric patients after cardiovascular surgery at Christus Muguerza High Specialty Hospital in ... Read more >>

SAGE Open Med (SAGE Open Medicine)
[2020, 8:2050312120910353]

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Urgent double switch operation in a patient with congenitally corrected transposition of great arteries and an untrained systemic ventricle.

Mehmet Salih Bilal, Arda Özyüksel, Mustafa Kemal Avşar, Özgür Yıldırım,

Congenitally corrected transposition of the great arteries is a rare cardiac abnormality. A nine-month-old male infant with the diagnosis of congenitally corrected transposition of the great arteries was admitted to our clinic with a history of pulmonary artery banding to train the left ventricle three months ago. On admission, he ... Read more >>

Turk Gogus Kalp Damar Cerrahisi Derg (Turk gogus kalp damar cerrahisi dergisi)
[2020, 28(1):197-200]

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Effectiveness of Bidirectional Glenn Shunt Placement for Palliation in Complex Congenitally Corrected Transposed Great Arteries.

Kai Ma, Lei Qi, Zhongdong Hua, Keming Yang, Hao Zhang, Shoujun Li, Sen Zhang, Fengpu He, Guanxi Wang,

Surgery for complex congenitally corrected transposed great arteries is one of the greatest challenges in cardiovascular surgery. We report our experience with bidirectional Glenn shunt placement as a palliative procedure for complex congenitally corrected transposition. We retrospectively identified 50 consecutive patients who had been diagnosed with congenitally corrected transposition accompanied ... Read more >>

Tex Heart Inst J (Texas Heart Institute journal)
[2020, 47(1):15-22]

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Exome-Based Case-Control Analysis Highlights the Pathogenic Role of Ciliary Genes in Transposition of the Great Arteries.

Xuanyu Liu, Wen Chen, Wenke Li, James R Priest, Yuanyuan Fu, Kunjing Pang, Baihui Ma, Bianmei Han, Xuewen Liu, Shengshou Hu, Zhou Zhou,

RATIONALE:Transposition of the great arteries (TGA) is one of the most severe types of congenital heart diseases. Understanding the clinical characteristics and pathogenesis of TGA is, therefore, urgently needed for patient management of this severe disease. However, the clinical characteristics and genetic cause underlying TGA remain largely unexplored. OBJECTIVE:We sought ... Read more >>

Circ. Res. (Circulation research)
[2020, 126(7):811-821]

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Left Ventricular Stiffness in Adolescents and Young Adults After Arterial Switch Operation for Complete Transposition of the Great Arteries.

Chuan Wang, Vivian Wing-Yi Li, Edwina Kam-Fung So, Yiu-Fai Cheung,

We tested the hypothesis that left ventricular (LV) myocardial stiffness is altered in patients with transposition of great arteries (TGA) after arterial switch operation (ASO) and explored its associations with myocardial calibrated integrated backscatter (cIB) and LV myocardial deformation. Thirty-one patients and twenty-two age-matched controls were studied. LV myocardial stiffness ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2020, :]

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Decreased Brain Volumes and Infants With Congenital Heart Disease Undergoing Venoarterial Extracorporeal Membrane Oxygenation.

Brandon K Chao, Nathalie H P Claessens, Jessie Mei Lim, Carolina Gorodetsky, Stephanie H Au-Young, Anne-Marie Guerguerian, Davide Marini, Susan Blaser, Manohar Shroff, Amandeep K Saini, Mike Seed, Vann Chau, Steven P Miller,

OBJECTIVES:The aims of this study were to: i) determine the spectrum of brain injury and ii) compare brain volumes between pre- and postoperative brain MRI in the infants receiving extracorporeal membrane oxygenation compared with those who did not require extracorporeal membrane oxygenation. DESIGN:Cohort study of infants with D-transposition of the ... Read more >>

Pediatr Crit Care Med (Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies)
[2020, :]

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Ciliary Genes Causing Transposition of the Great Arteries? Not Silly at All.

Barry London,

Circ. Res. (Circulation research)
[2020, 126(7):822-823]

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Aortic atresia with transposition of the great arteries.

Takuma Fukunishi, Kagami Miyaji, Takashi Miyamoto, Nobuyuki Inoue, Tadashi Kitamura,

We describe a rare case of newborn with aortic atresia and transposition of the great arteries who underwent successful surgical repair. To the best of our knowledge, no such case has been previously reported. We demonstrated that, even with a complex diagnosis, the patient could survive after rapid two-stage Norwood ... Read more >>

Gen Thorac Cardiovasc Surg (General thoracic and cardiovascular surgery)
[2020, :]

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Prenatal diagnosis of congenitally corrected transposition of the great arteries.

Nathalie Jeanne Bravo-Valenzuela, Alberto Borges Peixoto, Edward Araujo Júnior,

Congenitally corrected transposition of the great arteries is a rare and complex congenital heart disease. It essentially occurs with atrioventricular and ventriculoarterial discordance, in which the great vessels become parallel. Cases of corrected transposition of the great arteries are more frequently associated with other cardiac anomalies. In the fetus, corrected ... Read more >>

J Ultrason (Journal of ultrasonography)
[2019, 19(79):314-317]

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Left Atrial Volumetric and Deformation Analysis in Adult Patients with Dextro-Transposition of the Great Arteries (Insights from the CSONGRAD Registry and MAGYAR-Path Study).

Attila Nemes, Gergely Rácz, Árpád Kormányos, Péter Domsik, Anita Kalapos, Nándor Gyenes, Nóra Ambrus, Gábor Bogáts, István Hartyánszky, Kálmán Havasi,

BACKGROUND:In complete or dextro-transposition of the great arteries (dTGA), the aorta and the pulmonary artery are transposed. The present study was designed to examine dTGAassociated left atrial (LA) volumetric and functional abnormalities in adult patients late after repair and to compare their results to those of healthy controls. METHODS:The present ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(2):]

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Global longitudinal strain correlates to systemic right ventricular function.

Daniel Samarai, Sandra Lindstedt Ingemansson, Ronny Gustafsson, Ulf Thilén, Joanna Hlebowicz,

BACKGROUND:The aim of this retrospective study was to evaluate the relationship between right ventricular function derived from cardiac magnetic resonance imaging (CMR), echocardiography and exercise stress test performance, NT-proBNP (N-terminal proB-type natriuretic peptide) level and NYHA class in patients with a systemic right ventricle. METHODS:All patients with congenitally corrected transposition ... Read more >>

Cardiovasc Ultrasound (Cardiovascular ultrasound)
[2020, 18(1):4]

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Comprehensive Functional Echocardiographic Assessment of Transposition of the Great Arteries: From Fetus to Newborn.

Carin Walter, Iris Soveral, Joaquim Bartrons, María Clara Escobar, Juan Manuel Carretero, Laura Quirado, Olga Gómez, Joan Sánchez-de-Toledo,

To improve the understanding of the pathophysiology of transposition of the great arteries with intact ventricular septum (TGA/IVS) and the cardiac remodeling occurring from fetal to neonatal life, we performed a morphometric and functional echocardiographic assessment in fetuses and newborns. This was a prospective case-control study performed in a tertiary ... Read more >>

Pediatr Cardiol (Pediatric cardiology)
[2020, :]

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Intramural coronary pattern in patients with transposition: incidence and impact on follow-up.

Maciej Moll, Jadwiga A Moll, Jacek J Moll, Monika Łubisz, Krzysztof W Michalak,

OBJECTIVES:Coronary complications are still the main reason for early mortality after an arterial switch operation. The high incidence of coronary anomalies in patients with transposition of the great arteries may increase the difficulty of coronary transfer, and among them, an intramural pattern was shown to be an independent risk factor ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2020, :]

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Attention-deficit/hyperactivity disorder symptoms in children with surgically corrected Ventricular Septal Defect, Transposition of the Great Arteries, and Tetralogy of Fallot.

Line M Holst, Jonas B Kronborg, Jens R M Jepsen, Jette Ø Christensen, Niels G Vejlstrup, Klaus Juul, Jesper V Bjerre, Niels Bilenberg, Hanne B Ravn,

BACKGROUND:Children with complex CHD are at risk for psychopathology such as severe attention-deficit/hyperactivity disorder symptoms after congenital heart surgery. OBJECTIVE:The aim of this study was to investigate if children with Ventricular Septal Defect, Transposition of Great Arteries, or Tetralogy of Fallot have an increased occurrence of attention-deficit/hyperactivity disorder symptoms compared ... Read more >>

Cardiol Young (Cardiology in the young)
[2020, :1-8]

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Preoperative simulation for complex transposition of great arteries using a three-dimensional model.

Shinya Yokoyama, Ryohei Fukuba, Kazuhiro Mitani, Hideki Uemura,

We utilised a cast preoperatively prepared on the basis of the patient's computed tomography data to clarify unusual orientation of the great arteries (transposition of great arteries, coarctation of the aorta, and abnormally branching central pulmonary arteries) in a 2.2-kg neonate. The three-dimensional model was very useful for designing the ... Read more >>

Cardiol Young (Cardiology in the young)
[2019, :1-3]

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Timing of Interventions in Infants and Children with Congenital Heart Defects.

Balaji Arvind, Anita Saxena,

Congenital heart defects (CHD) are the most common form of birth anomalies. About one-fifth of these are critical requiring very early intervention, the classical examples being transposition of great arteries or obstructive total anomalous pulmonary venous connection. On the other hand, relatively milder and simpler lesions, such as small ventricular septal ... Read more >>

Indian J Pediatr (Indian journal of pediatrics)
[2020, 87(4):289-294]

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