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Phenotypic comparison between smoking and non-smoking chronic obstructive pulmonary disease.

Sundeep S Salvi, Bill B Brashier, Jyoti Londhe, Kanchan Pyasi, Vandana Vincent, Shilpa S Kajale, Sajid Tambe, Kuldeep Mandani, Arjun Nair, Sze Mun Mak, Sapna Madas, Sanjay Juvekar, Louise E Donnelly, Peter J Barnes,

BACKGROUND:Although COPD among non-smokers (NS-COPD) is common, little is known about this phenotype. We compared NS-COPD subjects with smoking COPD (S-COPD) patients in a rural Indian population using a variety of clinical, physiological, radiological, sputum cellular and blood biomarkers. METHODS:Two hundred ninety subjects (118 healthy, 79 S-COPD, 93 NS-COPD) performed pre- ... Read more >>

Respir. Res. (Respiratory research)
[2020, 21(1):50]

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Smoking prevalence in the area of responsibility of the German Ministry of Defense - results of the employee survey in the context of occupational health management.

Stefan Sammito, Annika Claus, Dirk-Matthias Rose,

BACKGROUND:Tobacco use, correlated with reduced physical fitness, is one of the leading causes of avoidable death worldwide. It increases the risk of dementia and can shorten the lifespan by 10 years. For the German Armed Forces (Bundeswehr), figures on smoking behavior have not been comprehensively captured. This study analyzes current data ... Read more >>

Mil Med Res (Military Medical Research)
[2020, 7(1):5]

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Passive Smoking Exposure and Perceived Health Status in Children Seeking Pediatric Care Services at a Vietnamese Tertiary Hospital.

Chau Quy Ngo, Giap Van Vu, Phuong Thu Phan, Hanh Thi Chu, Lan Phuong Thi Doan, Anh Tu Duong, Quan-Hoang Vuong, Manh-Tung Ho, Minh-Hoang Nguyen, Hong-Kong T Nguyen, Hai Thanh Phan, Giang Hai Ha, Giang Thu Vu, Kiet Tuan Huy Pham, Tung Hoang Tran, Bach Xuan Tran, Carl A Latkin, Cyrus S H Ho, Roger C M Ho,

Understanding the predictors of health conditions and exposure to secondhand smoke among children is necessary to determine the severity of the issues and identify effective solutions. Despite the significant prevalence in smoking and child exposure to secondhand smoke, there have been only a few studies focusing on this area in ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(4):]

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Mediterranean diet during pregnancy and childhood respiratory and atopic outcomes: birth cohort study.

Annabelle Bédard, Kate Northstone, A John Henderson, Seif O Shaheen,

Evidence for associations between Mediterranean diet during pregnancy and childhood asthma, allergy and related outcomes is conflicting. Few cohorts have followed children to school age, and none have considered lung function.In the Avon Longitudinal Study of Parents and Children, we analysed associations between maternal Mediterranean diet score during pregnancy (estimated ... Read more >>

Eur. Respir. J. (The European respiratory journal)
[2020, 55(3):]

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Respiratory surveillance in mineral dust-exposed workers.

Clare Wood, Deborah Yates,

Recently, there has been a worldwide resurgence in pneumoconiosis, or pulmonary fibrosis due to occupational mineral dust exposure. In Queensland, Australia, there has been a re-emergence of coal workers' pneumoconiosis and silicosis. Some coal mining communities have experienced a resurgence of progressive massive fibrosis in the USA and a worldwide ... Read more >>

Breathe (Sheff) (Breathe (Sheffield, England))
[2020, 16(1):190632]

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Facilitators and barriers to the self-management of COPD: a qualitative study from rural Nepal.

Uday Narayan Yadav, Jane Lloyd, Hassan Hosseinzadeh, Kedar Prasad Baral, Sagar Dahal, Narendra Bhatta, Mark Fort Harris,

OBJECTIVE:To understand the facilitators and barriers to the self-management of chronic obstructive pulmonary disease (COPD) in rural Nepal. SETTINGS:Community and primary care centres in rural Nepal. PARTICIPANTS:A total of 14 participants (10 people with COPD and 4 health care providers) were interviewed. PRIMARY AND SECONDARY OUTCOME MEASURES:People with COPD and ... Read more >>

BMJ Open (BMJ open)
[2020, 10(3):e035700]

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Self-management practice, associated factors and its relationship with health literacy and patient activation among multi-morbid COPD patients from rural Nepal.

Uday Narayan Yadav, Jane Lloyd, Hassan Hosseinzadeh, Kedar Prasad Baral, Narendra Bhatta, Mark Fort Harris,

BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is a progressive and debilitating condition that affects individuals' quality of life. COPD self-management and supports provided by carers is key to the quality of life people living with COPD. Health literacy (HL) and Patient Activation (PA) are main drivers of self-management practices (SMPs). However, ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):300]

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Complications and discomfort after research bronchoscopy in the MicroCOPD study.

Elise Orvedal Leiten, Tomas Mikal Lind Eagan, Einar Marius Hjellestad Martinsen, Eli Nordeide, Gunnar Reksten Husebø, Kristel Svalland Knudsen, Sverre Lehmann, Øistein Svanes, Per Sigvald Bakke, Rune Nielsen,

BACKGROUND:Data on discomfort and complications from research bronchoscopy in chronic obstructive pulmonary disease (COPD) and asthma is limited. We present complications and discomfort occurring within a week after bronchoscopy, and investigate personal and procedural risk factors. METHODS:239 subjects with COPD, asthma or without lung disease underwent research bronchoscopies as part ... Read more >>

BMJ Open Respir Res (BMJ open respiratory research)
[2020, 7(1):]

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Physical performances show conflicting associations in aged manual workers.

Kristoffer L Norheim, Afshin Samani, Jakob H Bønløkke, Øyvind Omland, Pascal Madeleine,

Ageing is associated with a decrease in physical performance implying that aged manual workers may be unable to match the physical requirements of their jobs. In this cross-sectional study, 96 male manual workers aged 51-72 years were recruited. Outcomes included handgrip strength (HGS), fat-free mass (FFM), fat percentage, cardiorespiratory fitness ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):2254]

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Effects of indium exposure on respiratory symptoms: a retrospective cohort study in Japanese workers using health checkup data.

Toshiharu Mitsuhashi,

Background:Indium compounds are known health hazards for lung cancer and interstitial pneumonia. Furthermore, they are related to emphysema, alveolar proteinosis, and cholesterol granuloma. In Japan, laws were revised in 2013 to tighten regulations on indium exposure in workplaces. However, its impact on the health of workers who handle indium has ... Read more >>

PeerJ (PeerJ)
[2020, 8:e8413]

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Assessment of Respiratory Problems in Workers Associated with Intensive Poultry Facilities in Pakistan.

Roheela Yasmeen, Zulfiqar Ali, Sean Tyrrel, Zaheer Ahmad Nasir,

Background:The poultry industry in Pakistan has flourished since the 1960s; however, there are scarce data regarding the impact of occupational exposure on the pulmonary health of farm workers in terms of years working in the industry. The objective of the present study was to assess the effect of poultry environment ... Read more >>

Saf Health Work (Safety and health at work)
[2020, 11(1):118-124]

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Gestation and lactation exposure to nicotine induces transient postnatal changes in lung alveolar development.

Sanja Blaskovic, Yves Donati, Filippo Zanetti, Isabelle Ruchonnet-Métrailler, Sylvain Lemeille, Tiziana P Cremona, Johannes C Schittny, Constance Barazzone-Argiroffo,

Harmful consequences of cigarette smoke (CS) exposure during lung development can already manifest in infancy. In particular, early life exposure to nicotine, the main component of CS, was shown to affect lung development in animal models. We aimed to characterize the effect of nicotine on alveoli formation. We analyzed the ... Read more >>

Am. J. Physiol. Lung Cell Mol. Physiol. (American journal of physiology. Lung cellular and molecular physiology)
[2020, 318(4):L606-L618]

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An inflammatory stimulus sensitizes TRPA1 channel to increase cytokine release in human lung fibroblasts.

Jennifer Maries Go Yap, Takashi Ueda, Norihisa Takeda, Kensuke Fukumitsu, Satoshi Fukuda, Takehiro Uemura, Tomoko Tajiri, Hirotsugu Ohkubo, Ken Maeno, Yutaka Ito, Yoshihiro Kanemitsu, Akio Niimi,

External stimuli such as cigarette smoke and house dust mite are often involved in the development and exacerbation of asthma. These risk factors could activate or sensitize transient receptor potential channel ankyrin 1 (TRPA1), which are primarily expressed in neuronal structures but also in non-neuronal cells such as fibroblasts. However, ... Read more >>

Cytokine (Cytokine)
[2020, 129:155027]

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Update: Interim Guidance for Health Care Professionals Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use-Associated Lung Injury and for Reducing the Risk for Rehospitalization and Death Following Hospital Discharge - United States, December 2019.

Mary E Evans, Evelyn Twentyman, Eleanor S Click, Alyson B Goodman, David N Weissman, Emily Kiernan, Susan Adkins Hocevar, Christina A Mikosz, Melissa Danielson, Kayla N Anderson, Sascha Ellington, Matthew J Lozier, Lori A Pollack, Dale A Rose, Vikram Krishnasamy, Christopher M Jones, Peter Briss, Brian A King, Jennifer L Wiltz, , ,

MMWR Morb. Mortal. Wkly. Rep. (MMWR. Morbidity and mortality weekly report)
[2020, 68(5152):1189-1194]

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Thinking in paracoccidioidomycosis: a delayed diagnosis of a neglected tropical disease, case report and review of clinical reports and eco-epidemiologic data from Colombia since the 2000.

Deving Arias Ramos, John Alexander Alzate, Ángela María Giraldo Montoya, Yessica Andrea Trujillo, Leidy Yurany Arias Ramos,

BACKGROUND:Paracoccidioidomycosis is a neglected tropical disease, endemic in several countries of South America including Colombia. We report a case of a patient with Chronic Multifocal Paracoccidioidomycosis with long-standing symptoms and a delayed diagnosis caused by several barriers to achieve it. We did a review of the papers published in Colombia ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2020, 20(1):119]

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Lung clearance index in healthy volunteers, measured using a novel portable system with a closed circuit wash-in.

Alex R Horsley, Amnah Alrumuh, Brooke Bianco, Katie Bayfield, Joanne Tomlinson, Andrew Jones, Anirban Maitra, Steve Cunningham, Jaclyn Smith, Catherine Fullwood, Anand Pandyan, Francis J Gilchrist,

INTRODUCTION:Lung clearance index (LCI) is a sensitive measure of early lung disease, but adoption into clinical practice has been slow. Challenges include the time taken to perform each test. We recently described a closed-circuit inert gas wash-in method that reduces overall testing time by decreasing the time to equilibration. The ... Read more >>

PLoS ONE (PloS one)
[2020, 15(2):e0229300]

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Smokers with COPD Show a Shift in Energy and Nitrogen Metabolism at Rest and During Exercise.

Olaf Holz, David S DeLuca, Stefan Roepcke, Thomas Illig, Klaus M Weinberger, Christian Schudt, Jens M Hohlfeld,

Purpose:There is an ongoing demand for easily accessible biomarkers that reflect the physiological and pathophysiological mechanisms of COPD. To test if an exercise challenge could help to identify clinically relevant metabolic biomarkers in COPD. Patients and Methods:We performed two constant-load exercise challenges separated by 4 weeks including smokers with COPD ... Read more >>

Int J Chron Obstruct Pulmon Dis (International Journal of Chronic Obstructive Pulmonary Disease)
[2020, 15:1-13]

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Patterns of Cancer-Related Risk Behaviors Among Construction Workers in Hong Kong: A Latent Class Analysis Approach.

Nan Xia, Wendy Lam, Pamela Tin, Sungwon Yoon, Na Zhang, Weiwei Zhang, Ke Ma, Richard Fielding,

Background:Hong Kong's construction industry currently faces a manpower crisis. Blue-collar workers are a disadvantaged group and suffer higher levels of chronic diseases, for example, cancer, than the wider population. Cancer risk factors are likely to cluster together. We documented prevalence of cancer-associated lifestyle risk behaviors and their correlates among Hong ... Read more >>

Saf Health Work (Safety and health at work)
[2020, 11(1):26-32]

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MTHFR, XRCC1 and OGG1 genetic polymorphisms in breast cancer: a case-control study in a population from North Sardinia.

Matteo Floris, Daria Sanna, Paolo Castiglia, Carlo Putzu, Valeria Sanna, Antonio Pazzola, Maria Rosaria De Miglio, Francesca Sanges, Giovanna Pira, Antonio Azara, Emanuele Lampis, Antonello Serra, Ciriaco Carru, Maristella Steri, Flavia Costanza, Marco Bisail, Maria Rosaria Muroni,

BACKGROUND:Despite conflicting results, considerable evidence suggests the association between single nucleotide polymorphisms in MTHFR, XRCC1 and OGG1 genes and, risk of developing breast cancer. Here a case-control study is reported, including 135 breat cancer patients and 112 healthy women, all representative of Northern Sardinian population. METHODS:Polymerase chain reaction/restriction fragment length ... Read more >>

BMC Cancer (BMC cancer)
[2020, 20(1):234]

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The psychometric properties of the Italian adaptation of the Health Orientation Scale (HOS).

M Masiero, S Oliveri, I Cutica, D Monzani, F Faccio, K Mazzocco, G Pravettoni,

BACKGROUND:A novel approach suggested that cognitive and dispositional features may explain in depth the health behaviors adoption and the adherence to prevention programs. The Health Orientation Scale (HOS) has been extensively used to map the adoption of health and unhealthy behaviors according to cognitive and dispositional features. Coherently, the main ... Read more >>

Health Qual Life Outcomes (Health and quality of life outcomes)
[2020, 18(1):69]

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Oral smokeless tobacco consumption pattern among rural Indian cancer patients: A prospective survey.

Avinash Pandey, Anjana Singh, Shivkant Singh, Amit Kumar, Anshuman Das, Heena Shahi, Aishwarya Singh,

Background:Oral tobacco consumption predisposes to cancer. The pattern of its use in rural Indian cancer patients is unknown. Aim:The aim of this study is to estimate the prevalence of oral tobacco consumption in cancer patients. Objectives:To identify oral tobacco consumption pattern with respect to demographic variables and clinical profiles in ... Read more >>

South Asian J Cancer (South Asian journal of cancer)
[2020, 9(1):17-19]

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The stability of the ADO score among UK COPD patients from The Health Improvement Network.

Spencer J Keene, Peymane Adab, Frank de Vries, Frits M E Franssen, Alice Sitch, James Martin, Tom Marshall, Rachel Jordan,

The ADO (age, dyspnoea, airflow obstruction) score predicts 3-year overall mortality among chronic obstructive pulmonary disease (COPD) patients. Information on the changes in COPD prognostic scores is sparse and it is unclear if the ADO score should be measured serially. We followed 4804 UK COPD patients with three or more ... Read more >>

ERJ Open Res (ERJ open research)
[2020, 6(1):]

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Asthma and hypercapnic respiratory failure.

P K Shamil, Nitesh Gupta, Sumita Agrawal, Pranav Ish, Shibdas Chakrabarti,

Hypercapnia is an uncommon entity in asthma exacerbation. Meticulous evaluation for the underlying aetiology of hypercapnia is warranted in these patients. http://bit.ly/2sTKTk2. ... Read more >>

Breathe (Sheff) (Breathe (Sheffield, England))
[2020, 16(1):190311]

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Race, Ethnicity, Socioeconomic Status, and Chronic Lung Disease in the U.S.

Shervin Assari, Hamid Chalian, Mohsen Bazargan,

BackgroundHigher socioeconomic status (SES) indicators such as educational attainment and income reduce the risk of chronic lung diseases (CLDs) such as Chronic Obstructive Pulmonary Disease (COPD), emphysema, chronic bronchitis, and asthma. Marginalization-related Diminished Returns (MDRs) refer to smaller health benefits of high SES for marginalized populations such as racial and ... Read more >>

Res Health Sci (Research in health science)
[2020, 5(1):48-63]

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Multicentre Covariate Adjustment Analysis of Short-Term and 5-Year Outcomes after Endovascular Repair according to Sex.

Bibombe P. Mwipatayi, Rebekah L. W Tan, Joseph Faraj, Ali Daneshmand, Olufemi Oshin, Nishath Altaf, Shannon D. Thomas, Patrik J Tosenovsky, Jackie Wong, Vikram Vijayan, Anthony J. Freeman, Sally A. Burrows,

Background Several studies have reported worse outcomes in women compared to men after endovascular aneurysm repair (EVAR). This study aimed to evaluate sex-specific short-term and 5-year outcomes after EVAR. Methods A total of 409 consecutive patients underwent elective EVAR from 2004 to 2017 at two tertiary hospitals in Western Australia. ... Read more >>

Surg Res Pract (Surgery research and practice)
[2020, 2020:]

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