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Therapeutic Injections for Pain Management

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Ketofol performance to reduce postoperative emergence agitation in children undergoing adenotonsillectomy.

Idress Ali, Murad Alahdal, Haifa Xia, Arafa S El Moughrabi, Huang Shiqian, Shanglong Yao,

Background: Emergence agitation is a reformed state of mindfulness, which starts with a sudden form of anesthesia and progresses through the early repossession age. Thus, the purpose of this study is to evaluate 1:3 ketofol performance on children 3-15 years old undergoing adenotonsillectomy.Methods: A total of 60 children aged 3-15 ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2020, 15(1):1688450]

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Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis.

Hunter L Bohlen, Zachary E Schwartz, Victor J Wu, Stephen G Thon, Zachary J Finley, Michael J O'Brien, Felix H Savoie,

Background:Medial epicondylitis (ME) is characterized as an overuse injury resulting in pathological alterations of the common flexor tendon at the elbow. Platelet-rich plasma (PRP) has recently become of interest in the treatment of musculoskeletal conditions as an alternative to operative management. Purpose:To compare the outcomes of recalcitrant type 1 ME ... Read more >>

Orthop J Sports Med (Orthopaedic Journal of Sports Medicine)
[2020, 8(3):2325967120908952]

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Intervertebral Disc Diseases PART 2: A Review of the Current Diagnostic and Treatment Strategies for Intervertebral Disc Disease.

Pang Hung Wu, Hyeun Sung Kim, Il-Tae Jang,

With an aging population, there is a proportional increase in the prevalence of intervertebral disc diseases. Intervertebral disc diseases are the leading cause of lower back pain and disability. With a high prevalence of asymptomatic intervertebral disc diseases, there is a need for accurate diagnosis, which is key to management. ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(6):]

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Special emphasis on bone health management in prostate cancer patients: a prospective longitudinal study.

Ashish Sharma, Rahul Janak Sinha, Gaurav Garg, Samarth Agarwal, Asif Akhtar Statistician, Vishwajeet Singh,

INTRODUCTION:Use of androgen deprivation therapy (ADT) in carcinoma prostate (CaP) has deleterious effect on bone mineral density (BMD) leading to increase incidence of osteoporosis and skeletal-related events. We evaluated bone health status and impact of bone-directed therapy (BDT) and ADT on BMD in these patients from Jan 2015-Dec 2018. MATERIALS ... Read more >>

Int Braz J Urol (International braz j urol : official journal of the Brazilian Society of Urology)
[2020, 46(3):363-373]

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Ultrasound-guided caudal epidural steroid injection for successful treatment of radiculopathy during pregnancy.

Timothy M Connolly, Danielle Nadav, Semih Gungor,

Aim: The aim of this case report is to describe ultrasound guidance for caudal epidural steroid injection during pregnancy. Case report: A 29-year-old, 32-week parturient presented with severe back and leg pain with MRI demonstrating herniation of the L5-S1 level. The disabling pain was refractory to conservative therapy, and an ... Read more >>

Pain Manag (Pain management)
[2020, 10(2):67-71]

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Human umbilical cord mesenchymal stem cells to treat spinal cord injury in the early chronic phase: study protocol for a prospective, multicenter, randomized, placebo-controlled, single-blinded clinical trial.

Yang Yang, Mao Pang, Yu-Yong Chen, Liang-Ming Zhang, Hao Liu, Jun Tan, Bin Liu, Li-Min Rong,

Human umbilical cord mesenchymal stem cells (hUC-MSCs) support revascularization, inhibition of inflammation, regulation of apoptosis, and promotion of the release of beneficial factors. Thus, they are regarded as a promising candidate for the treatment of intractable spinal cord injury (SCI). Clinical studies on patients with early chronic SCI (from 2 ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(8):1532-1538]

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The knowledge and self-management educational needs of older adults with knee osteoarthritis: A qualitative study.

Siti Salwana Kamsan, Devinder Kaur Ajit Singh, Maw Pin Tan, Saravana Kumar,

Knee osteoarthritis (KOA) is closely related with ageing, physical disability and functional dependency. The course of KOA is considered progressive and irreversible. Engagement with self-management may, however, minimize the impact of KOA. To be fully engaged with self-management activities, knowledge about KOA is a prerequisite. There is limited empirical data ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0230318]

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Sphenopalatine Ganglion Pulsed Radiofrequency for the Treatment of Refractory Chronic SUNCT and SUNA: A Prospective Case Series.

Raffaele Ornello, Stefano Palmisani, Madeleine Murphy, Simona Sacco, Adnan Al-Kaisy, Giorgio Lambru,

OBJECTIVES:We aimed to evaluate the safety and effectiveness of sphenopalatine ganglion pulsed radiofrequency (SPG-PRF) for the treatment of patients with refractory chronic short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and with cranial autonomic symptoms (SUNA). BACKGROUND:SPG-PRF is a minimally invasive, non-neurodestructive procedure already tested in refractory ... Read more >>

Headache (Headache)
[2020, :]

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Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group.

Steven P Cohen, Arun Bhaskar, Anuj Bhatia, Asokumar Buvanendran, Tim Deer, Shuchita Garg, W Michael Hooten, Robert W Hurley, David J Kennedy, Brian C McLean, Jee Youn Moon, Samer Narouze, Sanjog Pangarkar, David Anthony Provenzano, Richard Rauck, B Todd Sitzman, Matthew Smuck, Jan van Zundert, Kevin Vorenkamp, Mark S Wallace, Zirong Zhao,

BACKGROUND:The past two decades have witnessed a surge in the use of lumbar facet blocks and radiofrequency ablation (RFA) to treat low back pain (LBP), yet nearly all aspects of the procedures remain controversial. METHODS:After approval by the Board of Directors of the American Society of Regional Anesthesia and Pain ... Read more >>

Reg Anesth Pain Med (Regional anesthesia and pain medicine)
[2020, :]

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Platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: A meta-analysis.

Zehan Chen, Chang Wang, Di You, Shishun Zhao, Zhe Zhu, Meng Xu,

BACKGROUND:This meta-analysis focuses on the controversial efficacy and safety of platelet-rich plasma (PRP) as compared with hyaluronic acid (HA) in the clinical treatment of knee osteoarthritis. We have attempted to provide an evidence-based medicine protocol for the conservative treatment of knee osteoarthritis. In addition, we included the latest relevant literature ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(11):e19388]

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Injection Techniques for Common Chronic Pain Conditions of the Hand: A Comprehensive Review.

Ivan Urits, Daniel Smoots, Lekha Anantuni, Prudhvi Bandi, Katie Bring, Amnon A Berger, Hisham Kassem, Anh L Ngo, Alaa Abd-Elsayed, Laxmaiah Manchikanti, Richard Urman, Alan Kaye, Omar Viswanath,

INTRODUCTION:This compilation presents a comprehensive review of the literature on common chronic pain conditions of the hand. It briefly presents these common conditions with their biological background, diagnosis, and common management options. It then presents and compares the latest literature available for injection techniques to treat these diagnoses and compares ... Read more >>

Pain Ther (Pain and therapy)
[2020, :]

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The Effectiveness of Lumbar Transforaminal Injection of Steroid for the Treatment of Radicular Pain: A Comprehensive Review of the Published Data.

Clark C Smith, Zachary L McCormick, Ryan Mattie, John MacVicar, Belinda Duszynski, Milan P Stojanovic,

OBJECTIVE:To determine the effectiveness of lumbar transforaminal injection of steroid for the treatment of radicular pain. DESIGN:Comprehensive systematic review. OUTCOME MEASURES:The primary outcome of interest was the proportion of individuals with reduction of pain by ≥50%. Additional outcomes of interest were a more-than-two-point reduction in pain score, patient satisfaction, functional ... Read more >>

Pain Med (Pain medicine (Malden, Mass.))
[2020, 21(3):472-487]

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Effects of Astragalus injection and Salvia Miltiorrhiza injection on serum inflammatory markers in patients with stable coronary heart disease: a randomized controlled trial protocol.

Zhihao Luo, Yuntao Liu, Zhen Zhao, Xia Yan, Dawei Wang, Qing Liu,

BACKGROUND:Coronary heart disease (CHD) is a clinical syndrome caused by coronary atherosclerosis (AS) or functional changes in coronary arteries. We have previously reported that astragaloside IV (in astragalus) and tanshinone IIA (in Salvia miltiorrhiza) improve myocardial ischemic injury. METHODS:This study will employ the randomized, blinded, prospective, single-center experiments approach. Briefly, ... Read more >>

Trials (Trials)
[2020, 21(1):267]

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Antinociceptive effect of intrathecal injection of miR-9-5p modified mouse bone marrow mesenchymal stem cells on a mouse model of bone cancer pain.

Chao Zhu, Kun Wang, Zhi Chen, Yingchao Han, Hao Chen, Quan Li, Zude Liu, Lie Qian, Jun Tang, Hongxing Shen,

BACKGROUND:A growing body of studies have indicated that bone marrow mesenchymal stem cells (BMSCs) have powerful analgesic effects in animal models of bone cancer pain. Here, we explored the molecular mechanisms underlying how BMSCs alleviate pain sensation in a mouse model of bone cancer pain. METHODS:C3H/HeN adult male mice were ... Read more >>

J Neuroinflammation (Journal of neuroinflammation)
[2020, 17(1):85]

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Injection Techniques for Common Chronic Pain Conditions of the Foot: A Comprehensive Review.

Ivan Urits, Daniel Smoots, Henry Franscioni, Anjana Patel, Nathan Fackler, Seth Wiley, Amnon A Berger, Hisham Kassem, Richard D Urman, Laxmaiah Manchikanti, Alaa Abd-Elsayed, Alan D Kaye, Omar Viswanath,

PURPOSE OF REVIEW:This is a comprehensive literature review of the available evidence and techniques of foot injections for chronic pain conditions. It briefly describes common foot chronic pain syndromes and then reviews available injection techniques for each of these syndromes, weighing the available evidence and comparing the available approaches. RECENT ... Read more >>

Pain Ther (Pain and therapy)
[2020, :]

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Effectiveness of orthoses for treatment in patients with spinal pain.

Yoo Jin Choo, Min Cheol Chang,

Spinal pain is a common patient complaint in clinical practice. Conservative treatment methods include oral medication, physical therapy, injections, and spinal orthoses. The clinical application of orthoses is debated because of potential complications associated with long-term use, such as muscle weakness and joint contracture. We reviewed the orthoses most frequently ... Read more >>

Yeungnam Univ J Med (Yeungnam University journal of medicine)
[2020, :]

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Distal esophageal spasm: Update on diagnosis and management in the era of high-resolution manometry.

Harika Gorti, Salih Samo, Nikrad Shahnavaz, Emad Qayed,

Distal esophageal spasm (DES) is a rare major motility disorder in the Chicago classification of esophageal motility disorders (CC). DES is diagnosed by finding of ≥ 20% premature contractions, with normal lower esophageal sphincter (LES) relaxation on high-resolution manometry (HRM) in the latest version of CCv3.0. This feature differentiates it ... Read more >>

World J Clin Cases (World Journal of Clinical Cases)
[2020, 8(6):1026-1032]

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How have the views on myofascial pain and its treatment evolved in the past 20 years? From spray and stretch and injections to pain science, dry needling and fascial treatments.

Jan Dommerholt,

Pain Manag (Pain management)
[2020, 10(2):63-66]

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Injections of concentrated bone marrow aspirate as treatment for Discogenic pain: a retrospective analysis.

Michael Wolff, Jon Mark Shillington, Christopher Rathbone, Shawn K Piasecki, Brian Barnes,

BACKGROUND:There are an overwhelming number of patients suffering from low back pain (LBP) resulting from disc pathology. Although several strategies are being developed pre-clinically, simple strategies to treat the large number of patients currently affected is still needed. One option is to use concentrated bone marrow aspirate (cBMA), which may ... Read more >>

BMC Musculoskelet Disord (BMC Musculoskeletal Disorders)
[2020, 21(1):135]

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Symptomatic Intrathecal Hematoma following an Epidural Blood Patch for an Obstetric Patient with Postdural Puncture Headache: A Case Report and Synthesis of the Literature.

Hailey J. McInerney, Manuel Lee, Tracie Saunders, Joy Schabel, Rishimani S. N. Adsumelli,

Epidural blood patch (EBP), generally considered a low-risk procedure, can potentially lead to significant neurological complications. We report the case of a parturient who underwent an uneventful EBP for postdural puncture headache (PDPH) and subsequently presented with progressively worsening radicular symptoms. Magnetic resonance imaging (MRI) revealed an intrathecal hematoma, and ... Read more >>

(Case Reports in Anesthesiology)
[2020, 2020:]

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Correction to: Injection Techniques for Common Chronic Pain Conditions of the Hand: A Comprehensive Review.

Ivan Urits, Daniel Smoots, Lekha Anantuni, Prudhvi Bandi, Katie Bring, Amnon A Berger, Hisham Kassem, Anh L Ngo, Alaa Abd-Elsayed, Laxmaiah Manchikanti, Richard Urman, Alan D Kaye, Omar Viswanath,

The mid initial of one of the authors. ... Read more >>

Pain Ther (Pain and therapy)
[2020, :]

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International Society for the Advancement of Spine Surgery Guideline-Intraosseous Ablation of the Basivertebral Nerve for the Relief of Chronic Low Back Pain.

Morgan Lorio, Olivier Clerk-Lamalice, Douglas P Beall, Terrence Julien,

This International Society for the Advancement of Spine Surgery guideline is generated to respond to growing requests for background, supporting literature and evidence, and proper coding for intraosseous ablation of the basivertebral nerve for chronic low back pain. ... Read more >>

Int J Spine Surg (International Journal of Spine Surgery)
[2020, 14(1):18-25]

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Definition, Diagnosis, Treatment, and Prognosis of Frozen Shoulder: A Consensus Survey of Shoulder Specialists.

Chul-Hyun Cho, Yong-Ho Lee, Du-Hwan Kim, Young-Jae Lim, Chung-Sin Baek, Du-Han Kim,

Background:The objective of this study was to identify a consensus on definition, diagnosis, treatment, and prognosis of frozen shoulder (FS) among shoulder specialists. Methods:A questionnaire composed of 18 questions about FS-definition, classification, utilization of diagnostic modalities, the propriety of treatment at each stage, and prognosis-was sent to 95 shoulder specialists ... Read more >>

Clin Orthop Surg (Clinics in orthopedic surgery)
[2020, 12(1):60-67]

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Efficacy of Hyalase Hydrodissection in the Treatment of Carpal Tunnel Syndrome: A Randomized, Double-Blind, Controlled, Clinical Trial.

Abdelraheem Elawamy, Manal Hassanien, Ahmed Hamed, Al Shimaa Ismael Roushdy, Nisreen Adel Abass, Ghada Mohammed, Mohamed Raouf Abdel Razek Hasan, Emad Zarief Kamel,

BACKGROUND:Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy, which results from median nerve compression. A lot of nonsurgical modalities are available for the management of mild to moderate situations. Local Hyalase hydrodissection (HD) of the entrapped median nerve could offer a desirable sustained symptom alleviation. OBJECTIVES:To evaluate the ... Read more >>

Pain Physician (Pain physician)
[2020, 23(2):E175-E183]

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Minimally Invasive Treatment of Chronic Ankle Instability: a Comprehensive Review.

Ivan Urits, Morgan Hasegawa, Vwaire Orhurhu, Jacquelin Peck, Angele C Kelly, Rachel J Kaye, Mariam Salisu Orhurhu, Joseph Brinkman, Stephen Giacomazzi, Lukas Foster, Laxmaiah Manchikanti, Alan D Kaye, Omar Viswanath,

PURPOSE OF REVIEW:Chronic ankle pain is a prevalent and significant cause of chronic pain. While the definition of chronic ankle pain is heterogeneous and poorly defined in the literature, systematic reviews and meta-analyses have estimated this condition to be a prevalent and debilitating source of chronic pain. The most identifiable ... Read more >>

Curr Pain Headache Rep (Current pain and headache reports)
[2020, 24(3):8]

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