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The HSN egg-laying command neurons regulate the defecation motor program in Caenorhabditis elegans: Integration.

Bhavya Ravi, Jessica Garcia, Kevin Collins,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

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Brain functional remodeling caused by sciatic nerve transposition repair in rats identified by multiple-model resting-state blood oxygenation level-dependent functional magnetic resonance imaging analysis.

Yu-Song Yuan, Hai-Lin Xu, Zhong-Di Liu, Yu-Hui Kou, Bo Jin, Pei-Xun Zhang,

Lower extremity nerve transposition repair has become an important treatment strategy for peripheral nerve injury; however, brain changes caused by this surgical procedure remain unclear. In this study, the distal stump of the right sciatic nerve in a rat model of sciatic nerve injury was connected to the proximal end ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(2):418-426]

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Lower and upper motor neuron involvement and their impact on disease prognosis in amyotrophic lateral sclerosis.

Maria N Zakharova, Anna A Abramova,

Amyotrophic lateral sclerosis is a fatal neurodegenerative disease characterized by progressive muscle wasting, breathing and swallowing difficulties resulting in patient's death in two to five years after disease onset. In amyotrophic lateral sclerosis, both upper and lower motor neurons of the corticospinal tracts are involved in the process of neurodegeneration, ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(1):65-73]

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Pioglitazone improves skeletal muscle functions in reserpine-induced fibromyalgia rat model.

Fatma E Hassan, Hader I Sakr, Passant M Mohie, Howayda Saeed Suliman, Ayman Saber Mohamed, Mohamed H Attia, Dalia M Eid,

<h4>Background</h4>Fibromyalgia (FM) is characterized by musculoskeletal pain, fatigue, sleep and memory disturbance. There is no definitive cure yet for FM-related health problems. Peroxisome proliferator-activated receptor's (PPAR's) activation is associated with insulin sensitisation and improved glucose metabolism. PPAR-γ was reported to alleviate FM allodynia. Limited data are discussing its effect on ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1032-1040]

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Genetic Creutzfeldt-Jakob disease shows fatal family insomnia phenotype.

Bin Chen, Shan Zhang, Ying Xiao, Yingman Wu, Weiting Tang, Limin Yan, Zhengxue Zhang, Shengquan Qin, Mingming Dai, Yong You,

We report a case of genetic Creutzfeldt-Jakob disease (gCJD), which has a clinical phenotype that is highly similar to Fatal Family Insomnia (FFI) and has a triad of Wernicke-Korsakoff syndrome (WKs) at the developmental stage of the disease. The 51-year-old male complained of sleep disorder and imbalance who had visited ... Read more >>

Prion (Prion)
[2021, 15(1):177-182]

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Comprehending Optimality of Finger Flexor Tendon Pulley System Using Computational Analysis.

Vitthal Khatik, Shyam Sunder Nishad, Anupam Saxena,

Existing prosthetic/orthotic designs are rarely based on kinetostatics of a biological finger, especially its tendon-pulley system (TPS). Whether a biological TPS is optimal for use as a reference, say for design purposes, and if so, in what sense, is also relatively unknown. We expect an optimal TPS to yield a ... Read more >>

J Biomech Eng (Journal of biomechanical engineering)
[2021, 143(11):]

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Extensor Carpi Ulnaris Subluxation.

Jacqueline N Byrd, Sarah E Sasor, Kevin C Chung,

Extensor carpi ulnaris tendon subluxation can be a challenging diagnosis as a cause of wrist pain. The tendon is stabilized by a tough subsheath. This subsheath is vulnerable to tears in acute wrist movements, especially those combining supination, flexion, and ulnar deviation. The patient presenting acutely may experience swelling, tenderness, ... Read more >>

Hand Clin (Hand clinics)
[2021, 37(4):487-491]

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Tendon Reconstruction With Cadaveric Allograft in a Patient With Flexor Tendon Injury Without Treatment for Six Months

Carolina Lizarzaburu-Ortiz, Daniela Dominguez, Ian Valdez, Eduardo Rojas, Diego J Lizarzaburu,

We present the case of an 18-year-old male patient with a penetrating lesion at zone II of the flexor compartment of the left hand. During surgery, complete reabsorption of the second deep and superficial flexor tendons was evidenced, prompting the decision to perform a two-stage procedure. First, a spacer was ... Read more >>

Cureus (Cureus)
[0, 13(9):]

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The male sling for stress urinary incontinence: tips and tricks for success.

Brian M Inouye, Hayley A Premo, Dane Weil, Andrew C Peterson,

Urethral slings are a good treatment option for mild male stress urinary incontinence. There are many different sling options, but herein our group describes our techniques with the Advance® and Virtue® slings. More important than technique, we strongly think that patient selection is paramount to sling success. We only offer ... Read more >>

Int Braz J Urol (International braz j urol : official journal of the Brazilian Society of Urology)
[2021, 47(6):1131-1135]

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Sharp pain in a normal Achilles tendon of a professional female football player was related to a plantaris tendon in a rare position: a case report.

Håkan Alfredson, Lorenzo Masci, Christoph Spang,

Plantaris tendinopathy and plantaris-associated Achilles tendinopathy can be responsible for chronic pain in the Achilles tendon midportion, often accompanied by medial tenderness. As conservative treatments are less successful for this patient group, proper diagnosis is important for decision making. This report presents a case with plantaris tendinopathy in a rare ... Read more >>

J Med Case Rep (Journal of medical case reports)
[2021, 15(1):513]

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Retraction Note to: Evaluation of the pulley function of the hamulus of the hamate for the flexor tendons.

Kenji Goto, Kiyohito Naito, Yoichi Sugiyama, Mayuko Kinoshita, Nana Nagura, Yoshiyuki Iwase, Kazuo Kaneko,

Surg Radiol Anat (Surgical and radiologic anatomy : SRA)
[2021, 43(11):1905]

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Global Research Trends in Stem Cells for Tendon from 1991 to 2020: A Bibliometric and Visualized Study

Huibin Long, Ziyang Yuan, Heyong Yin, Bo Yang, Ai Guo,

<h4>Background: </h4> Tendinopathy is a disabling musculoskeletal disorder affecting the athletic and general populations. There have been increased studies using stem cells in treating tendon diseases. The aim of this bibliometric and visualized study is to comprehensively investigate the current status and global trends of research in stem cells for ... Read more >>

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Adipogenic differentiation was inhibited by downregulation of PPARγ signaling pathway in aging tendon stem/progenitor cells.

Fan Lai, Jingjing Wang, Hong Tang, Xuting Bian, Kang Lu, Gang He, Pan Huang, Juan Liu, Mei Zhou, Jian Liu, Xu Tao, Kang-Lai Tang,

Tendon stem/progenitor cells (TSPCs) play a vital role in tendon repair and regeneration. Previously we found more adipocytes accumulated in the patellar tendon injury sites in aging rats compared with the young ones, of which the mechanism is still unknown. Here, we want to identify whether erroneous differentiation of TSPCs ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):614]

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Pulsed electromagnetic field therapy alters early healing in a rat model of rotator cuff injury and repair: Potential mechanisms.

Julianne Huegel, Peter Y W Chan, Stephanie N Weiss, Courtney A Nuss, Harina Raja, Erik I Waldorff, Nianli Zhang, James T Ryaby, Louis J Soslowsky, Andrew F Kuntz,

Rotator cuff repair failure remains common due to poor tendon healing, particularly at the enthesis. We previously showed that pulsed electromagnetic field (PEMF) therapy improved the mechanical properties of the rat supraspinatus tendon postoperatively. However, little is known about the mechanisms behind PEMF-dependent contributions to improved healing in this injury ... Read more >>

J Orthop Res (Journal of orthopaedic research : official publication of the Orthopaedic Research Society)
[2021, :]

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The ulnar collateral ligament loading paradox between in-vitro and in-vivo studies on baseball pitching (narrative review).

Bart Van Trigt, Liset W Vliegen, Ton Ajr Leenen, DirkJan Hej Veeger,

Ulnar collateral ligament (UCL) weakening or tears occur in 16% of professional baseball pitchers. To prevent players from sustaining a UCL injury, it is important to understand the relationship between the UCL properties and elbow stabilizers with the load on the UCL during pitching. In-vitro studies showed that the ultimate ... Read more >>

Int Biomech (International biomechanics)
[2021, 8(1):19-29]

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Spinal Anesthesia Is Superior to General Anesthesia for Percutaneous Achilles Tenotomy in Infants.

Karthick Rangasamy, Indu Sen, Nirmal Raj Gopinathan,

J Pediatr Orthop (Journal of pediatric orthopedics)
[2021, 41(10):e935]

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Noncanonical Wnt5a signaling regulates tendon stem/progenitor cells senescence.

Minhao Chen, Yingjuan Li, Longfei Xiao, Guangchun Dai, Panpan Lu, Yunfeng Rui,

The structural and functional properties of tendon decline with age, and these changes contribute to tendon disorder. Tendon stem/progenitor cells (TSPCs) play a vital role in tendon repair, regeneration and homeostasis maintaining. Although studies have demonstrated that tendon aging is closely associated with the altered TSPCs function on senescence, the ... Read more >>

Stem Cell Res Ther (Stem cell research & therapy)
[2021, 12(1):544]

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The release of adhesions improves outcome following minimally invasive repair of Achilles tendon rupture.

Michael R Carmont, Sara Brandt Knutsson, Annelie Brorsson, Jón Karlsson, Katarina Nilsson-Helander,

Operative repair of Achilles tendon rupture may lead to complications, which influence outcome adversely. The aim of this study was to determine the incidence, impact and response to treatment of post-operative adhesions. From February 2009 to 2021, 248 patients operated on with percutaneous or minimally invasive surgical repair have been ... Read more >>

Knee Surg Sports Traumatol Arthrosc (Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA)
[2021, :]

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Effectiveness of platelet-rich plasma injections for the treatment of acute Achilles tendon rupture : A systematic review and meta-analysis

Chenglong Wang, Hua Fan, Yuhuan Li, Zhihe Yun, Zhuo Zhang, Qingsan Zhu,

Abstract <h4>Background:</h4> The effect of platelet-rich plasma (PRP) on patients with acute Achilles tendon rupture is still controversial. The purpose of this systematic review is to assess the efficacy of PRP injections treating acute Achilles tendon rupture. <h4>Methods:</h4> A comprehensive electronic literature search was performed in the PubMed, Embase, Cochrane ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(41):]

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Combined therapy of platelet-rich plasma and basic fibroblast growth factor using gelatin-hydrogel sheet for rotator cuff healing in rat models.

Takeshi Kataoka, Yutaka Mifune, Atsuyuki Inui, Hanako Nishimoto, Takashi Kurosawa, Kohei Yamaura, Shintaro Mukohara, Takehiko Matsushita, Takahiro Niikura, Yasuhiko Tabata, Ryosuke Kuroda,

Excellent outcomes of arthroscopic rotator cuff repair for small and medium tears have been recently reported. However, re-tears after surgery have been a common complication after surgical repair of large and massive rotator cuff tears and often occur in early postoperative phase. It was previously reported that basic fibroblast growth ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):605]

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Citrate-based mussel-inspired magnesium whitlockite composite adhesives augmented bone-to-tendon healing.

Xiaowei Yuan, Yitao Zhao, Jintao Li, Xuncai Chen, Zhihui Lu, Lianyong Li, Jinshan Guo,

Citrate-based mussel-inspired whitlockite composite adhesives (CMWAs) were developed and administered to the bone-tendon interface in anterior cruciate ligament (ACL) reconstruction. CMWAs could improve the initial bone-tendon bonding strength, promote the bony inward growth from the bone tunnel and enhance the chondrogenesis and osteogenesis of the bone-tendon interface, thus augmenting bone-to-tendon ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2021, 9(39):8202-8210]

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Midterm outcome and strength assessment after proximal rectus femoris refixation in athletes

Maximilian Hinz, Stephanie Geyer, Felix Winden, Alexander Braunsperger, Florian Kreuzpointner, Benjamin D. Kleim, Andreas B. Imhoff, Julian Mehl,

<h4>Purpose</h4> Proximal rectus femoris avulsions (PRFA) are relatively rare injuries that occur predominantly among young soccer players. The aim of this study was to evaluate midterm postoperative results including strength potential via standardized strength measurements after proximal rectus femoris tendon refixation. It was hypothesized that the majority of competitive athletes ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2021, :1-8]

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Validation and cross-cultural adaptation of the Korean translation of the Achilles tendon Total Rupture Score.

Young Hwan Park, Hyun Woo Cho, Jung Woo Choi, Hak Jun Kim,

<h4>Background</h4>The Achilles tendon Total Rupture Score (ATRS) is a widely used patient-reported outcome measure to assess clinical outcomes of Achilles tendon rupture, but it has not been validated in Korean yet. The purpose of this study was to translate the ATRS into Korean and evaluate its reliability and validity in ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2021, 22(1):876]

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Graft tunnel integration occurs early in the tibial tunnel compared with the femoral tunnel after anterior cruciate ligament reconstruction with preserved insertion hamstring tendon graft.

Ravi Gupta, Sandeep Singh, Anil Kapoor, Ashwani Soni, Ravinder Kaur, Narinder Kaur,

<h4>Background</h4>Preservation of hamstring tendon insertion at the time of anterior cruciate ligament (ACL) reconstruction is a well-known technique; however, its effect on graft integration is not well studied. The present study was conducted to study the graft integration inside the tibial and femoral tunnels, respectively, after ACL reconstruction using hamstring ... Read more >>

Knee Surg Relat Res (Knee surgery & related research)
[2021, 33(1):37]

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Irreducible Monteggia Fracture-Dislocation Secondary to an Entrapped Brachialis Tendon: A Case Report.

McKayla Kelly, Justin Turcotte, Alexander Shushan, Jeffrey Gelfand,

<h4>Case</h4>A 7-year-old boy sustained a Monteggia fracture-dislocation. Corrective osteotomy of the ulna was performed to restore proper forearm anatomy and achieve radial head reduction. Recurrent radial head instability was noted postoperatively, and magnetic resonance imaging indicated recurrent dislocation of the radial head with, notably, an entrapped brachialis tendon and annular ... Read more >>

JBJS Case Connect (JBJS case connector)
[2021, 11(4):]

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