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The protein kinase G orthologs, EGL-4 and PKG-2, mediate serotonin-induced paralysis of C. elegans.

Andrew Olson, Michael Koelle,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

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Characterizing Dynein's Role in P-cell Nuclear Migration using an Auxin-Induced Degradation System.

Jamie Ho, Venecia A Valdez, Linda Ma, Daniel A Starr,

MicroPubl Biol (microPublication biology)
[2018, 2018:]

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Serum leptin levels are positively associated with aortic stiffness in patients with chronic kidney disease stage 3-5.

Jing-Wun Lu, Po-Jui Chi, Yu-Li Lin, Chih-Hsien Wang, Bang-Gee Hsu,

Leptin potentially exerts atherogenic effects.This study evaluated the relationship between serum leptin levels and aortic stiffness in patients with stage 3-5 chronic kidney disease (CKD). Totally 205 participants were enrolled. Fasting blood sample were checked and serum leptin were measured by enzyme immunoassay. Aortic stiffness was measured as the carotid-femoral ... Read more >>

Adipocyte (Adipocyte)
[2020, 9(1):206-211]

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Flexural behavior of bamboo–concrete composite beams with perforated steel plate connections

Zhiyuan Wang, Yang Wei, Ning Li, Kang Zhao, Mingmin Ding,

A new type of bamboo–concrete composite structure using perforated steel plates as connectors was proposed. To study the composite effect of this new type of composite structure, the slip behavior of bamboo–concrete shear connectors was first studied through push-out tests. Subsequently, four-point bending tests of ten bamboo–concrete composite beams were ... Read more >>

(Journal of wood science.)
[2020, 66(1):4]

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Radial augmentation index may be an effective predictor of vascular calcification in patients on peritoneal dialysis.

Ning Yang, Wei Yang, Wenting Cui, Dan Zhou, Xiangning Du, Longkai Li,

Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expensive predictors, such as the radial augmentation index ... Read more >>

Ren Fail (Renal failure)
[2020, 42(1):455-462]

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Serum osteoprotegerin level is positively associated with peripheral artery disease in patients with peritoneal dialysis.

Wei-Chen Lin, Jen-Pi Tsai, Yu-Hsien Lai, Yu-Li Lin, Chiu-Huang Kuo, Chih-Hsien Wang, Bang-Gee Hsu,

Osteoprotegerin (OPG) is a potential biomarker of cardiovascular disease complications and severity. Peripheral arterial disease (PAD) is associated with an increased risk of death in patients on peritoneal dialysis (PD). Therefore, this study aimed to evaluate the relationship between serum OPG levels and PAD by measuring the ankle-brachial index (ABI) ... Read more >>

Ren Fail (Renal failure)
[2020, 42(1):131-136]

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Carotid arterial stiffness is increased and related to left ventricular function in patients with hypertrophic cardiomyopathy.

Monica Roşca, Leonard Mandeş, Daniela Ciupercă, Andreea Călin, Carmen C Beladan, Roxana Enache, Ruxandra Jurcuţ, Ioan M Coman, Carmen Ginghină, Bogdan A Popescu,

AIMS:To assess the carotid mechanical properties in patients with hypertrophic cardiomyopathy and the relation between arterial stiffness and left ventricular function in this setting. METHODS AND RESULTS:We have prospectively enrolled 71 patients (52 ± 16 years, 34 men) with hypertrophic cardiomyopathy, divided into two groups depending on the presence (46 patients) or absence ... Read more >>

Eur Heart J Cardiovasc Imaging (European heart journal cardiovascular Imaging)
[2020, 21(8):923-931]

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Aortic stiffness-Is kynurenic acid a novel marker? Cross-sectional study in patients with persistent atrial fibrillation.

Tomasz Zapolski, Anna Kamińska, Tomasz Kocki, Andrzej Wysokiński, Ewa M Urbanska,

Although a number of modifiable and non-modifiable causes were implicated in arterial stiffness, its pathogenesis remains elusive, and very little is known about aortic elasticity in supraventricular arrhythmias. The potential role of disturbed kynurenine metabolism in the pathogenesis of cardiovascular disease has been recently suggested. Thus, we studied the correlations ... Read more >>

PLoS ONE (PloS one)
[2020, 15(7):e0236413]

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Comparing Oscillometric and Tonometric Methods to Assess Pulse Wave Velocity: a population-based study.

Rosaria Del Giorno, Chiara Troiani, Sofia Gabutti, Kevyn Stefanelli, Luca Gabutti,

Background. Oscillometric pulse wave velocity (o-PWV) represents an attractive, non invasive and non operator-dependent method to estimate arterial stiffness. Tonometric carotid-femoral measurements (cf-PWV),are considered the gold-standard for non-invasive aortic stiffness assessment. To date, no studies in the general population comparing the two methods have been performed. Methods and Results. 1162 ... Read more >>

Ann. Med. (Annals of medicine)
[2020, :1-34]

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Platelet counts are associated with arterial stiffness in Chinese Han population: a longitudinal study.

Kuo Liu, Junfeng Xu, Lixin Tao, Kun Yang, Yang Sun, Xiuhua Guo,

BACKGROUND:Determining the risk factors for brachial-ankle pulse wave velocity (baPWV) may help to identify people susceptible to diabetic atherosclerosis and could prevent diabetic macrovascular complications in the early stages. We aim to comprehensively investigate risk factors contributing to arterial stiffness in patients with and without diabetes. METHODS:BaPWV was measured in ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20(1):353]

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Estimated arterial stiffness and prediction of vascular aging: The rising of a new era.

Christina Antza, Ioannis Doundoulakis, Evangelos Akrivos, Stella Stabouli, Katerina Chrysaidou, Dimos Gidaris, Vasilios Kotsis,

Arterial stiffness has been associated with cardiovascular events and correlated with cardiovascular risk factors. In the new guidelines of the European Society of Hypertension, the evaluation of arterial stiffness, and specifically carotid-femoral pulse wave velocity (c-f PWV), was taken into account for the detailed screening of the hypertensive population. Despite ... Read more >>

Curr. Pharm. Des. (Current pharmaceutical design)
[2020, :]

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A Comparative Study for the Effects of Nifedipine GITS and Amlodipine Besylate Administrated in Daytime or at Nighttime on Recovery of Blood Pressure Rhythm and Arterial Stiffness in the Young and Middle-aged Subjects with Non-dipper Hypertension (NARRAS): Design and Rationale.

Jing Liu,

INTRODUCTION:Hypertensive patients with a blunted or absent nocturnal blood pressure (BP) drop (non-dipper) are associated with arterial stiffening and additional cardiovascular risk. Non-dipper hypertension is prevalent in young and middle-aged adults; but the optimal antihypertensive strategy remains unclear. There is a need to explore the effects of different antihypertensive agents ... Read more >>

Int. J. Clin. Pract. (International journal of clinical practice)
[2020, :e13628]

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Differences in longitudinal associations of cardiovascular risk factors with arterial stiffness and pressure wave reflection in middle-aged Japanese men.

Masatsune Fujii, Hirofumi Tomiyama, Hiroki Nakano, Yoichi Iwasaki, Chisa Matsumoto, Kazuki Shiina, Akira Yamashina, Taishiro Chikamori,

The present prospective observational study was conducted to examine the differences in longitudinal associations of the conventional risk factors for cardiovascular disease (CVD) with arterial stiffness and with abnormal pressure wave reflection using repeated measurement data. In 4016 healthy middle-aged (43 ± 9 years) Japanese men without CVD at baseline, the conventional ... Read more >>

Hypertens. Res. (Hypertension research : official journal of the Japanese Society of Hypertension)
[2020, :]

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Impact of acute mental stress on segmental arterial stiffness.

Daisuke Kume, Masato Nishiwaki, Norio Hotta, Hiroshi Endoh,

PURPOSE:It has been reported that acute brief episodes of mental stress (MS) result in a prolonged increase in carotid-femoral pulse wave velocity (cfPWV), an index of aortic stiffness. However, whether acute MS also impacts arterial stiffness in other segments is unclear. The present study aimed to examine the impact of ... Read more >>

Eur. J. Appl. Physiol. (European journal of applied physiology)
[2020, :]

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Effects of roflumilast on arterial stiffness in COPD (ELASTIC): A randomized trial.

Matthias H Urban, Nicole Kreibich, Andreas Gleiss, Georg-Christian Funk, Sylvia Hartl, Otto C Burghuber,

BACKGROUND AND OBJECTIVE:Cardiovascular risk is substantially increased in patients with COPD and can be quantified via arterial stiffness. The PDE-IV inhibitor roflumilast revealed a potential reduction of COPD-related cardiovascular risk. We aimed to investigate the effects of roflumilast on arterial stiffness by quantification of pulse wave velocity (PWV) in stable ... Read more >>

Respirology (Respirology (Carlton, Vic.))
[2020, :]

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The effects of betalain-rich cacti (dragon fruit and cactus pear) on endothelial and vascular function: a systematic review of animal and human studies.

Alex Cheok, Trevor W George, Ana Rodriguez-Mateos, Paul W Caton,

Dragon fruit (Hylocereus) and cactus pear (Opuntia) are cacti species that have been widely used globally as a reliable source of food as well as traditional folk remedies. They have become of scientific interest recently due to their high levels of bioactive phytochemical compounds, in particular betalains. Earlier systematic reviews ... Read more >>

Food Funct (Food & function)
[2020, :]

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Cardiorespiratory Fitness and Muscular Strength on Arterial Stiffness in Older Adults.

Emma E Albin, Angelique G Brellenthin, James A Lang, Jacob D Meyer, Duck-Chul Lee,

PURPOSE:To evaluate the independent and combined associations of cardiorespiratory fitness (CRF) and muscular strength (MS) with arterial stiffness (AS), a strong predictor of cardiovascular disease, in older adults. METHODS:This cross-sectional study included 405 older adults (mean age, 72 yr). Cardiorespiratory fitness was assessed by time (s) to complete a 400-m ... Read more >>

Med Sci Sports Exerc (Medicine and science in sports and exercise)
[2020, 52(8):1737-1744]

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High serum uric acid is associated with increased arterial stiffness in hypertension.

Li-Na An, Ning Rong, Min Ning, Liu-Liu Feng, Zhen-Han Chen, Wei-Qing Liu, Xiao-Chun Ouyang, Fan-Rong Diao, Zhi-Gang Han, Jiang Hong,

Serum uric acid level has been found to be associated with cerebrovascular diseases. However, whether serum uric acid level is a risk factor for arterial stiffness in the hypertension population is unclear. This study was designed to determine the relationship between serum uric acid level and arterial stiffness in the ... Read more >>

Aging (Albany NY) (Aging)
[2020, 12:]

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Exogenous adiponectin with full Peroxisome proliferator-activated receptor agonists (pioglitazone) abrogates streptozotocin induced oxidative stress and vascular abnormalities in Spontaneously hypertensive rats.

Sheryar Afzal, Munavvar Abdul Sattar, Edward James Johns, Olorunfemi. Eseyin,

Abstract Background Oxidative stress, associates with metabolic and anthropometric perturbations, leads to reactive oxygen species production and decrease in plasma adiponectin concentration. We investigated pharmacodynamically the pathophysiological role and potential implication of exogenously administered adiponectin with full and partial peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonists on modulation of oxidative stress, metabolic ... Read more >>

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The impact of heated tobacco products on arterial stiffness.

Klaas Frederik Franzen, Svenja Belkin, Torsten Goldmann, Michael Reppel, Henrik Watz, Kai Mortensen, Daniel Droemann,

Vasc Med (Vascular medicine (London, England))
[2020, :1358863X20943292]

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Association of Uric Acid in Serum and Urine with Arterial Stiffness: Hanzhong Adolescent Hypertension Study.

Yang Wang, Xiao-Yu Zhang, Wei-Hua Gao, Ming-Fei Du, Chao Chu, Dan Wang, Chen Chen, Yue Yuan, Qiong Ma, Yue-Yuan Liao, Yu Yan, Ke-Ke Wang, Jie Zhang, Ke Gao, Chun-Hua Li, Hao Li, Qiong Ma, Jia-Wen Hu, Ting Zou, Yue Sun, Min Li, Hao-Wei Zhou, Hao Jia, Jian-Jun Mu,

Background:Hyperuricemia has long been associated with increased cardiovascular risk, and arterial stiffness is proposed as a mediator. The present study is aimed at examining the associations of uric acid (UA) in blood and urine with arterial stiffness in a Chinese cohort. Methods:A total of 2296 participants (mean age: 43.0 years) ... Read more >>

Dis. Markers (Disease markers)
[2020, 2020:1638515]

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Repeated administration of inorganic nitrate on blood pressure and arterial stiffness: a systematic review and meta-analysis of randomized controlled trials.

Dandan Li, Stephanie K Nishi, Elena Jovanovski, Andreea Zurbau, Allison Komishon, Sonia Blanco Mejia, Tauseef A Khan, John L Sievenpiper, Davor Milicic, Alexandra Jenkins, Vladimir Vuksan,

OBJECTIVE:We aim to synthesize effects of repeated administration (≥3 days) of inorganic nitrate on blood pressure and arterial stiffness measures. METHODS:We conducted a systematic review and meta-analysis of randomized controlled trials with at least 3 days treatment of inorganic nitrate on blood pressure and arterial stiffness in individuals with or ... Read more >>

J. Hypertens. (Journal of hypertension)
[2020, :]

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Cardiovascular risk and heart rate variability in young adults with type 2 diabetes and arterial stiffness: The SEARCH for Diabetes in Youth Study.

Amy Sanghavi Shah, Mamta Jaiswal, Dana Dabelea, Jasmin Divers, Scott Isom, Angela D Liese, Jean M Lawrence, Grace Kim, Elaine M Urbina,

AIMS:To evaluate cardiovascular risk factors and heart rate variability (HRV) in young adults with type 2 diabetes and arterial stiffness and to explore the relationship between HRV and arterial stiffness. METHODS:We studied 185 young adults with youth-onset T2D enrolled in the SEARCH for Diabetes in Youth Study. Cardiovascular risk factors ... Read more >>

J. Diabetes Complicat. (Journal of diabetes and its complications)
[2020, :107676]

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Physical Function and Cardio-Ankle Vascular Index in Elderly Heart Failure Patients.

Akihiro Ogawa, Kazuhiro Shimizu, Takahiro Nakagami, Hiroshi Maruoka, Kohji Shirai,

The number of heart failure patients is increasing rapidly in Japan because of its large elderly population. As age increases, arterial stiffness and physical dysfunction progress. This study aimed to evaluate the association between the physical function and arterial stiffness in elderly heart failure patients.This retrospective, observational study includes data ... Read more >>

Int Heart J (International heart journal)
[2020, 61(4):769-775]

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Microcirculatory function deteriorates with advancing stages of chronic kidney disease independently of arterial stiffness and atherosclerosis.

Maria Schoina, Charalampos Loutradis, Evangelos Memmos, Theodoros Dimitroulas, Eleni Pagkopoulou, Michael Doumas, Asterios Karagiannis, Alexandros Garyfallos, Aikaterini Papagianni, Pantelis Sarafidis,

Cardiovascular disease is the main cause of mortality in chronic kidney disease (CKD). Endothelial dysfunction and capillary rarefaction are established cardiovascular risk factors. Nailfold video capillaroscopy provides a thorough assessment of capillary density and functional reserve. This study aimed to examine possible differences in structural and functional capillary density in ... Read more >>

Hypertens. Res. (Hypertension research : official journal of the Japanese Society of Hypertension)
[2020, :]

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