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A 10-year cohort study of 175 primary gastrointestinal lymphoma cases in Thailand: clinical features and outcomes in the immunochemotherapy era.

Weerapat Owattanapanich, Theera Ruchutrakool, Tawatchai Pongpruttipan, Monthira Maneerattanaporn,

<h4>Background</h4>Primary gastrointestinal lymphoma (PGIL), an uncommon subtype of lymphoma, accounts for 1%-4% of gastrointestinal cancers. This study, therefore, aimed to investigate the current 10-year epidemiology and outcomes of PGIL.<h4>Methods</h4>This retrospective study involved a hospital-based chart review to analyze the epidemiology, clinical features, predisposing factors, and clinical outcomes of patients diagnosed ... Read more >>

Hematology (Hematology (Amsterdam, Netherlands))
[2021, 26(1):249-255]

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Prognostic value of circulating clonal plasma cells in newly diagnosed multiple myeloma.

Wenmin Han, Yuanyuan Jin, Min Xu, Si-Shu Zhao, Qinglin Shi, Xiaoyan Qu, Run Zhang, Jianyong Li, Yujie Wu, Lijuan Chen,

<h4>Objectives</h4>Multiple myeloma (MM) involves a clinically and biologically heterogeneous malignancy of plasma cells. It is difficult to predict the prognosis of MM. The presence of circulating clonal plasma cells (CPC) has been associated with a worse prognosis in patients with MM.<h4>Methods</h4>This study retrospectively analysed CPC in 108 newly diagnosed MM ... Read more >>

Hematology (Hematology (Amsterdam, Netherlands))
[2021, 26(1):510-517]

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Lower and upper motor neuron involvement and their impact on disease prognosis in amyotrophic lateral sclerosis.

Maria N Zakharova, Anna A Abramova,

Amyotrophic lateral sclerosis is a fatal neurodegenerative disease characterized by progressive muscle wasting, breathing and swallowing difficulties resulting in patient's death in two to five years after disease onset. In amyotrophic lateral sclerosis, both upper and lower motor neurons of the corticospinal tracts are involved in the process of neurodegeneration, ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(1):65-73]

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Incidence and survival of head and neck cancer in the Faroe Islands.

Sunnvá Hanusardóttir Olsen, Jeppe Friborg, Bjarki Ellefsen, Kathrine Kronberg Jakobsen, Kasper Aanæs,

<b>Background:</b> The Faroese people constitute a geographically isolated population, and research on cancer in this population is sparse. Thus, this study aimed to calculate the age-standardised incidence rate (ASIR) and 5-year survival rates in head and neck cancers (HNC) in the Faroese population from 1985 to 2017.<b>Materials and methods:</b> All ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1894697]

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Prognostic Significance of Pretreatment Staging With 18F-FDG PET in Esophageal Cancer: A Nationwide Population-Based Study.

Hsi-Huei Lu, Nan-Ching Chiu, Mu-Hung Tsai,

<h4>Purpose of the report</h4>Without the routine use of 18F-FDG PET for initial staging of esophageal cancer, it may lead to inaccurate staging and suboptimal treatment. The purpose of this study was to evaluate the prognostic significance of pretreatment 18F-FDG PET in nonmetastatic esophageal cancer by comparing the survival between patients ... Read more >>

Clin Nucl Med (Clinical nuclear medicine)
[2021, 46(8):647-653]

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Automatic sleep staging by cardiorespiratory signals: a systematic review.

Farideh Ebrahimi, Iman Alizadeh,

<h4>Background</h4>Because of problems with the recording and analysis of the EEG signal, automatic sleep staging using cardiorespiratory signals has been employed as an alternative. This study reports on certain critical points which hold considerable promise for the improvement of the results of the automatic sleep staging using cardiorespiratory signals.<h4>Methods</h4>A systematic review.<h4>Results</h4>The ... Read more >>

Sleep Breath (Sleep & breathing = Schlaf & Atmung)
[2021, :]

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Down-staging Outcomes for Hepatocellular Carcinoma: Results from the Multicenter Evaluation of Reduction in Tumor Size before Liver Transplantation (MERITS-LT) Consortium.

Neil Mehta, Catherine Frenette, Parissa Tabrizian, Maarouf Hoteit, Jennifer Guy, Neehar Parikh, T Tara Ghaziani, Renu Dhanasekaran, Jennifer L Dodge, Brahma Natarajan, Matthew L Holzner, Leana Frankul, Wesley Chan, Austin Fobar, Sander Florman, Francis Y Yao,

<h4>Background/aims</h4>United Network of Organ Sharing (UNOS) has adopted uniform criteria for down-staging (UNOS-DS) of hepatocellular carcinoma (HCC) prior to liver transplantation (LT), but down-staging success rate and intention-to-treat outcomes across broad geographic regions are unknown.<h4>Methods</h4>In this first multi-regional study (7 centers, 4 UNOS regions), consecutive patients with HCC undergoing down-staging ... Read more >>

Gastroenterology (Gastroenterology)
[2021, :]

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Automatic Extraction of Lung Cancer Staging Information From Computed Tomography Reports: Deep Learning Approach.

Danqing Hu, Huanyao Zhang, Shaolei Li, Yuhong Wang, Nan Wu, Xudong Lu,

<h4>Background</h4>Lung cancer is the leading cause of cancer deaths worldwide. Clinical staging of lung cancer plays a crucial role in making treatment decisions and evaluating prognosis. However, in clinical practice, approximately one-half of the clinical stages of lung cancer patients are inconsistent with their pathological stages. As one of the ... Read more >>

JMIR Med Inform (JMIR medical informatics)
[2021, 9(7):e27955]

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MRI of nasopharyngeal carcinoma: parapharyngeal subspace involvement has prognostic value and influences T-staging in the IMRT era.

Wenjie Huang, Tingting Quan, Qin Zhao, Shuqi Li, Yi Cai, Jian Zhou, Chao Luo, Guangying Ruan, Chunyan Cui, Shaobo Liang, Haojiang Li, Lizhi Liu,

<h4>Objectives</h4>To identify the prognosis of parapharyngeal space involvement (PPSI) based on the number of subspaces involved (pre-styloid space, carotid space (CS), areas outside the CS) and explore its significance for current T-staging in patients with nasopharyngeal carcinoma (NPC).<h4>Methods</h4>PPSI was retrospectively identified in 1224 patients with non-disseminated NPC at two centers ... Read more >>

Eur Radiol (European radiology)
[2021, :]

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Ovarian cancer staging: What the surgeon needs to know.

Lucas Roberto Lelis Botelho de Oliveira, Natally Horvat, Pamela Ines Causa Andrieu, Pedro Sergio Brito Panizza, Giovanni Guido Cerri, Publio Cesar Cavalcante Viana,

Ovarian cancer (OC) is the leading cause of gynecological cancer death, and most cases are diagnosed at advanced stages due to a nonspecific and insidious clinical presentation. Radiologists play a critical role in the decision of which patients are candidates for primary debulking surgery and who may benefit from neoadjuvant ... Read more >>

Br J Radiol (The British journal of radiology)
[2021, :20210091]

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PET/MRI for Staging the Axilla in Breast Cancer: Current Evidence and the Rationale for SNB vs. PET/MRI Trials.

Rosa Di Micco, Letizia Santurro, Maria Luisa Gasparri, Veronica Zuber, Giovanni Cisternino, Sara Baleri, Manuela Morgante, Nicole Rotmensz, Carla Canevari, Francesca Gallivanone, Paola Scifo, Annarita Savi, Patrizia Magnani, Ilaria Neri, Nadia Ferjani, Elena Venturini, Claudio Losio, Isabella Sassi, Giampaolo Bianchini, Pietro Panizza, Luigi Gianolli, Oreste Davide Gentilini,

Axillary surgery in breast cancer (BC) is no longer a therapeutic procedure but has become a purely staging procedure. The progressive improvement in imaging techniques has paved the way to the hypothesis that prognostic information on nodal status deriving from surgery could be obtained with an accurate diagnostic exam. Positron ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(14):]

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Update on the Role of Imaging in Clinical Staging and Restaging of Renal Cell Carcinoma Based on the AJCC 8th Edition, From the AJR Special Series on Cancer Staging.

Asser Abou Elkassem, Brian C Allen, Kedar G Sharbidre, Soroush Rais-Bahrami, Andrew D Smith,

This article reviews the essential role of imaging in clinical staging and restaging of renal cell carcinoma (RCC). To completely characterize and stage an indeterminate renal mass, renal CT or MRI without and with IV contrast administration is recommended. The critical items for initial clinical staging of an indeterminate renal ... Read more >>

AJR Am J Roentgenol (AJR. American journal of roentgenology)
[2021, :1-15]

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Whole-body uptake classification and prostate cancer staging in 68Ga-PSMA-11 PET/CT using dual-tracer learning.

Nicolò Capobianco, Ludovic Sibille, Maythinee Chantadisai, Andrei Gafita, Thomas Langbein, Guenther Platsch, Esteban Lucas Solari, Vijay Shah, Bruce Spottiswoode, Matthias Eiber, Wolfgang A Weber, Nassir Navab, Stephan G Nekolla,

<h4>Purpose</h4>In PSMA-ligand PET/CT imaging, standardized evaluation frameworks and image-derived parameters are increasingly used to support prostate cancer staging. Clinical applicability remains challenging wherever manual measurements of numerous suspected lesions are required. Deep learning methods are promising for automated image analysis, typically requiring extensive expert-annotated image datasets to reach sufficient accuracy. ... Read more >>

Eur J Nucl Med Mol Imaging (European journal of nuclear medicine and molecular imaging)
[2021, :]

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Pelvic lymph node dissection in high-risk prostate cancer.

Luciano Haiquel, Xavier Cathelineau, Rafael Sanchez-Salas, Petr Macek, Fernando Secin,

<h4>Introduction</h4>The therapeutic role of pelvic lymph node dissection (PLND) in prostate cancer (PCa) is unknown due to absence of randomized trials.<h4>Objective</h4>to present a critical review on the therapeutic benefits of PLND in high risk localized PCa patients.<h4>Materials and methods</h4>A search of the literature on PLND was performed using PubMed, Cochrane, ... Read more >>

Int Braz J Urol (International braz j urol : official journal of the Brazilian Society of Urology)
[2022, 48:]

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Predicting survival in colorectal carcinoma after curative resection: a new prognostic nomogram.

Mahiar Mahjoub, Loretta Sioson, Amy Sheen, Mahsa Ahadi, Angela Chou, Anthony J Gill, Talia L Fuchs,

Several prognostic nomograms designed to predict survival after curative resection for colorectal cancer (CRC) have been proposed. Recently, routine pathological assessment has evolved with subtle changes to the AJCC staging system, and routine screening for mismatch repair deficiency (MMRd). Therefore we sought to develop and validate a new prognostic nomogram. ... Read more >>

Pathology (Pathology)
[2021, :]

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The Role of Ga-68-PSMA PET/CT in the Initial Staging of Prostate Cancer - A Single Center 4 Year Experience.

João P Lima, João Carvalho, Vasco Quaresma, Edgar Tavares-da-Silva, Rodolfo Silva, Paulo Azinhais, Gracinda Costa, Arnaldo Figueiredo,

<h4>Background</h4>Recommended imaging modalities for prostate cancer staging have disappointing sensitivities, whereas [68Ga]-PSMA PET/CT (PET-PSMA) shows promising sensitivities and specificities in the initial management of prostate cancer. Recent studies have revealed that a significant change of management when PET-PSMA was used, with favorable negative predictive values.<h4>Methods</h4>In this retrospective study, we analyzed ... Read more >>

Res Rep Urol (Research and reports in urology)
[2021, 13:479-485]

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Systematic review and meta-analysis of diagnostic performance of CT imaging for assessing resectability of pancreatic ductal adenocarcinoma after neoadjuvant therapy: importance of CT criteria.

Hyun Kyung Yang, Mi-Suk Park, Miyoung Choi, Jaeseung Shin, Seung Soo Lee, Woo Kyoung Jeong, Shin Hye Hwang, Sang Hyun Choi,

<h4>Purpose</h4>To assess the CT diagnostic performance for evaluating resectability of pancreatic ductal adenocarcinoma (PDAC) after neoadjuvant therapy and identify the factor(s) that affect(s) diagnostic performance.<h4>Methods</h4>Databases were searched to identify studies published from January 1, 2000, to November 5, 2019 that evaluated the CT diagnostic performance for assessing resectability of post-neoadjuvant ... Read more >>

Abdom Radiol (NY) (Abdominal radiology (New York))
[2021, :]

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The influence of 68Ga-prostate-specific membrane antigen PET/computed tomography on prostate cancer staging and planning of definitive radiation therapy.

Akram Al-Ibraheem, Fawzi Abuhijla, Samer Salah, Mohamed Shahait, Jamal Khader, Issa Mohamad, Ula Al-Rasheed, Kelsey L Pomykala, Ken Herrmann, Ramiz Abu-Hijlih,

<h4>Objectives</h4>Prostate-specific membrane antigen (PSMA) PET/computed tomography (CT) is a novel imaging tool with an evolving role in the management of prostate cancer. This study aims to retrospectively evaluate the impact of 68Ga-PSMA PET/CT on prostate cancer staging and definitive radiation therapy planning.<h4>Methods</h4>Between April 2015 and June 2020, 366 men with ... Read more >>

Nucl Med Commun (Nuclear medicine communications)
[2021, 42(7):811-817]

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Thymoma Staging: An Analysis of the Different Schemas.

Cesar A Moran,

Over the last years, a number of changes has taken place in the evaluation of thymomas. More recently, the introduction of a TNM staging system in the assessment of thymic epithelial tumors, in general, has been put forward. Important to highlight is that this TNM system is not based on ... Read more >>

Adv Anat Pathol (Advances in anatomic pathology)
[2021, :]

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The ROC Staging System for COVID-related Rhino-Orbital-Cerebral Mucormycosis.

Milind N Naik, Suryasnata Rath,

<b>Purpose</b>: To report and validate an objective staging system for COVID-related Rhino-Orbito-Cerebral mucormycosis (ROCM).<b>Methods</b>: Proof of concept of a new ROC staging system was devised for COVID-related ROCM. The staging system was based on data points drawn from a comprehensive ophthalmic examination, diagnostic endoscopy, and appropriate imaging of orbit, paranasal ... Read more >>

Semin Ophthalmol (Seminars in ophthalmology)
[2021, :1-5]

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Prognostic elements extraction from documents to detect prognostic stage.

Pratiksha R Deshmukh, Rashmi Phalnikar,

For cancer prediction, the prognostic stage is the main factor that helps medical experts to decide the optimal treatment for a patient. The main objective of this study is to predict prognostic stage from the medical records of various health institutions. Total 465 pathological and clinical reports of people living ... Read more >>

Comput Methods Biomech Biomed Engin (Computer methods in biomechanics and biomedical engineering)
[2021, :1-16]

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Revised points and disputed matters in the eighth edition of the TNM staging system for gastric cancer.

Koshi Kumagai, Takeshi Sano,

The American Joint Committee on Cancer and the Union for International Cancer Control have now released the eighth edition of the cancer staging system, which incorporates some major revisions concerning gastric cancer. First, grouping of pathological stages has been revised in accordance with a proposal from the International Gastric Cancer ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(7):1024-1027]

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Comparison of a Tumor-Ratio-Metastasis Staging System and the 8th AJCC TNM Staging System for Gastric Cancer.

Miaoquan Zhang, Chao Ding, Lin Xu, Biyi Ou, Shoucheng Feng, Guoqiang Wang, Wei Wang, Yao Liang, Yingbo Chen, Zhiwei Zhou, Haibo Qiu,

<h4>Background</h4>Despite the implementation of the 8th American Joint Committee on Cancer (AJCC) TNM staging system for gastric cancer (GC) in 2017, it still holds a significant level of stage migration which affects patients' proper classification and accurate prognosis. Here, to reduce this effect, we evaluated the prognostic value of a ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:595421]

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Can Biologic Aggressiveness and Metastatic Potential of Primary Lung Cancer Be Predicted from Clinical Staging Alone?

Farid M Shamji, Gilles Beauchamp,

The future biologic aggressiveness and metastatic potential of lung cancer, as in other cancers, cannot be predetermined from the current clinical information, imaging studies, and pathologic examination whose purpose is to provide diagnosis and mutation studies and molecular drivers only in making decision for treatment. There is a need for ... Read more >>

Thorac Surg Clin (Thoracic surgery clinics)
[2021, 31(3):357-366]

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The added value of PSMA PET/MR radiomics for prostate cancer staging.

Esteban Lucas Solari, Andrei Gafita, Sylvia Schachoff, Borjana Bogdanović, Alberto Villagrán Asiares, Thomas Amiel, Wang Hui, Isabel Rauscher, Dimitris Visvikis, Tobias Maurer, Kristina Schwamborn, Mona Mustafa, Wolfgang Weber, Nassir Navab, Matthias Eiber, Mathieu Hatt, Stephan G Nekolla,

<h4>Purpose</h4>To evaluate the performance of combined PET and multiparametric MRI (mpMRI) radiomics for the group-wise prediction of postsurgical Gleason scores (psGSs) in primary prostate cancer (PCa) patients.<h4>Methods</h4>Patients with PCa, who underwent [<sup>68</sup> Ga]Ga-PSMA-11 PET/MRI followed by radical prostatectomy, were included in this retrospective analysis (n = 101). Patients were grouped by psGS in ... Read more >>

Eur J Nucl Med Mol Imaging (European journal of nuclear medicine and molecular imaging)
[2021, :]

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