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Sleeplessness and Circadian Rhythm Disorder

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Sleep and Reproductive Health.

Olubodun Michael Lateef, Michael Olawale Akintubosun,

The reproductive function of humans is regulated by several sex hormones which are secreted in synergy with the circadian timing of the body. Sleep patterns produce generic signatures that physiologically drive the synthesis, secretion, and metabolism of hormones necessary for reproduction. Sleep deprivation among men and women is increasingly reported ... Read more >>

J Circadian Rhythms (Journal of Circadian Rhythms)
[2020, 18:]

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Folic Acid Supplementation Suppresses Sleep Deprivation-Induced Telomere Dysfunction and Senescence-Associated Secretory Phenotype (SASP).

Xiaoning Zhang, Yuwen Wang, Rui Zhao, Xianyun Hu, Baoren Zhang, Xin Lv, Zhenglong Guo, Zhiqiang Zhang, Jinghua Yuan, Xu Chu, Fei Wang, Guang Li, Xin Geng, Yang Liu, Lei Sui, Feng Wang,

Sleep deprivation is reported to cause oxidative stress and is hypothesized to induce subsequent aging-related diseases including chronic inflammation, Alzheimer's disease, and cardiovascular disease. However, how sleep deprivation contributes to the pathogenesis of sleep deficiency disorder remains incompletely defined. Accordingly, more effective treatment methods for sleep deficiency disorder are needed. ... Read more >>

Oxid Med Cell Longev (Oxidative Medicine and Cellular Longevity)
[2019, 2019:4569614]

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Forward genetic approach for behavioral neuroscience using animal models.

Hiromasa Funato,

Forward genetics is a powerful approach to understand the molecular basis of animal behaviors. Fruit flies were the first animal to which this genetic approach was applied systematically and have provided major discoveries on behaviors including sexual, learning, circadian, and sleep-like behaviors. The development of different classes of model organism ... Read more >>

Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. (Proceedings of the Japan Academy. Series B, Physical and biological sciences)
[2020, 96(1):10-31]

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Effect of Morning Light Glasses and Night Short-Wavelength Filter Glasses on Sleep-Wake Rhythmicity in Medical Inpatients.

Chiara Formentin, Stefano Carraro, Matteo Turco, Lisa Zarantonello, Paolo Angeli, Sara Montagnese,

Sleep and circadian rhythm disorders are common amongst medical inpatients. They are caused by a mixture of factors, including noise, loss of habitual daily routines, and abnormal exposure to light, which tends to be insufficient in the day and too high at night. The aim of the present study was ... Read more >>

Front Physiol (Frontiers in physiology)
[2020, 11:5]

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Most sleep does not serve a vital function: Evidence from Drosophila melanogaster.

Quentin Geissmann, Esteban J Beckwith, Giorgio F Gilestro,

Sleep appears to be a universally conserved phenomenon among the animal kingdom, but whether this notable evolutionary conservation underlies a basic vital function is still an open question. Using a machine learning-based video-tracking technology, we conducted a detailed high-throughput analysis of sleep in the fruit fly Drosophila melanogaster, coupled with ... Read more >>

Sci Adv (Science advances)
[2019, 5(2):eaau9253]

Cited: 2 times

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Shift work sleep disorders and associated factors among nurses at federal government hospitals in Ethiopia: a cross-sectional study.

Kalkidan Kassa Haile, Sintayehu Asnakew, Tsegereda Waja, Habtamu Bogale Kerbih,

OBJECTIVE:The current study was conducted to assess the prevalence and associated factors of shift work sleep disorder among nurses working at Ethiopian federal government hospitals in Addis Ababa. METHODS:An institutional-based, cross-sectional study was conducted from April to June 2018 using self-administered structured questionnaires. Computer-generated simple random sampling technique was used ... Read more >>

BMJ Open (BMJ open)
[2019, 9(8):e029802]

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Genetic sleep deprivation: using sleep mutants to study sleep functions.

Henrik Bringmann,

Sleep is a fundamental conserved physiological state in animals and humans. It may serve multiple functions, ranging from energy conservation to higher brain operation. Understanding sleep functions and the underlying mechanisms requires the study of sleeplessness and its consequences. The traditional approach to remove sleep is sleep deprivation (SD) by ... Read more >>

EMBO Rep. (EMBO reports)
[2019, 20(3):]

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Systematic Review of Sleep Disturbances and Circadian Sleep Desynchronization in Autism Spectrum Disorder: Toward an Integrative Model of a Self-Reinforcing Loop.

Claudia Carmassi, Laura Palagini, Danila Caruso, Isabella Masci, Lino Nobili, Antonio Vita, Liliana Dell'Osso,

Background: A compelling number of studies, conducted in both children and adults, have reported an association between sleep disturbances/circadian sleep alterations and autism spectrum disorder (ASD); however, the data are sparse and the nature of this link is still unclear. The present review aimed to systematically collect the literature data ... Read more >>

Front Psychiatry (Frontiers in Psychiatry)
[2019, 10:366]

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Using the Analytic Network Process Method for Prioritizing and Weighing Shift Work Disorders Among the Personnel of Hospitals of Kerman University of Medical Sciences.

Sajad Zare, Hossein Elahi Shirvan, Rasoul Hemmatjo, Mohammad Faridan, Masoud Hajghani, Behzad Fouladi Dehaghi,

Introduction:Increasing population, the need for services, and industrialization of societies have led to a growing demand for shift work. Shiftwork causes several disorders, and determining the weight of each disorders is important for their prevention and treatment. Therefore, the purpose of the present study was to use Analytic Network Process ... Read more >>

J Circadian Rhythms (Journal of circadian rhythms)
[2018, 16:10]

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Cross-sectional analysis of sleep hours and quality with sex hormones in men.

Morten Ruge, Tea Skaaby, Anna-Maria Andersson, Allan Linneberg,

Background:Reduced total hours of sleep and low quality of sleep have been suggested to be associated with low levels of male hormones. Few studies have examined the association between excessive sleep and male reproductive hormones. Objective:To investigate the association of total hours of sleep and quality of sleep with serum ... Read more >>

Endocr Connect (Endocrine connections)
[2019, 8(2):141-149]

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The medicalization of sleeplessness: Results of U.S. office visit outcomes, 2008-2015.

Mairead Eastin Moloney, Gabriele Ciciurkaite, Robyn Lewis Brown,

Previous analysis of U.S. physician office visits (1993-2007) indicated that the medicalization of sleeplessness was on the rise and had potentially negative implications for population health. Our study asks if the medicalization of sleeplessness at the level of patient-physician interaction has persisted over time. Using the most recent years available ... Read more >>

SSM Popul Health (SSM - population health)
[2019, 8:100388]

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Mental Sleep Activity and Disturbing Dreams in the Lifespan.

Serena Scarpelli, Chiara Bartolacci, Aurora D'Atri, Maurizio Gorgoni, Luigi De Gennaro,

Sleep significantly changes across the lifespan, and several studies underline its crucial role in cognitive functioning. Similarly, mental activity during sleep tends to covary with age. This review aims to analyze the characteristics of dreaming and disturbing dreams at different age brackets. On the one hand, dreams may be considered ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2019, 16(19):]

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Self-reported sleeplessness in 12,655 persons living in the north of Norway: The Tromsø Study.

Arne Fetveit, Jørund Straand, Bjørn Bjorvatn, Espen Saxhaug Kristoffersen,

Sleep Sci (Sleep science (Sao Paulo, Brazil))
[2019, 12(3):147-155]

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Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.

Ki-Bae Hong, Yooheon Park, Hyung Joo Suh,

The aim of this study was to evaluate the biological and sleep-promoting effects of combined γ-aminobutyric acid (GABA) and 5-hydroxytryptophan (5-HTP) using caffeine-induced sleepless fruit flies, ICR mice, and Sprague-Dawley rats.Video-tracking analysis was applied to investigate behavioral changes of Drosophila melanogaster. Pentobarbital-induced sleep test and electroencephalogram (EEG) patterns were used ... Read more >>

Nutr Res Pract (Nutrition research and practice)
[2018, 12(3):208-214]

Cited: 1 time

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Auriculotherapy for sleep quality in people with primary insomnia: A protocol for a systematic review and meta-analysis.

Runyuan Ren, Jiayuan Zhang, Tingting Zhang, Yangzhi Peng, Chenjian Tang, Qi Zhang,

BACKGROUND:Primary insomnia is one of the common sleep disorders. Auriculotherapy originated from traditional Chinese medicine, has been thought as a promising treatment for primary insomnia. We aim to evaluate the efficacy and safety of auriculotherapy for patients with primary insomnia through this systematic review. METHODS:Five English databases (Cochrane Central Register ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(8):e14621]

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Evidence for Genetic Correlations and Bidirectional, Causal Effects Between Smoking and Sleep Behaviors.

Mark Gibson, Marcus R Munafò, Amy E Taylor, Jorien L Treur,

INTRODUCTION:Cigarette smokers are at increased risk of poor sleep behaviors. However, it is largely unknown whether these associations are due to shared (genetic) risk factors and/or causal effects (which may be bidirectional). METHODS:We obtained summary-level data of genome-wide association studies of smoking (smoking initiation [n = 74 035], cigarettes per ... Read more >>

Nicotine Tob. Res. (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco)
[2019, 21(6):731-738]

Cited: 3 times

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Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.

Raymond Noordam, Maxime M Bos, Heming Wang, Thomas W Winkler, Amy R Bentley, Tuomas O Kilpeläinen, Paul S de Vries, Yun Ju Sung, Karen Schwander, Brian E Cade, Alisa Manning, Hugues Aschard, Michael R Brown, Han Chen, Nora Franceschini, Solomon K Musani, Melissa Richard, Dina Vojinovic, Stella Aslibekyan, Traci M Bartz, Lisa de Las Fuentes, Mary Feitosa, Andrea R Horimoto, Marjan Ilkov, Minjung Kho, Aldi Kraja, Changwei Li, Elise Lim, Yongmei Liu, Dennis O Mook-Kanamori, Tuomo Rankinen, Salman M Tajuddin, Ashley van der Spek, Zhe Wang, Jonathan Marten, Vincent Laville, Maris Alver, Evangelos Evangelou, Maria E Graff, Meian He, Brigitte Kühnel, Leo-Pekka Lyytikäinen, Pedro Marques-Vidal, Ilja M Nolte, Nicholette D Palmer, Rainer Rauramaa, Xiao-Ou Shu, Harold Snieder, Stefan Weiss, Wanqing Wen, Lisa R Yanek, Correa Adolfo, Christie Ballantyne, Larry Bielak, Nienke R Biermasz, Eric Boerwinkle, Niki Dimou, Gudny Eiriksdottir, Chuan Gao, Sina A Gharib, Daniel J Gottlieb, José Haba-Rubio, Tamara B Harris, Sami Heikkinen, Raphaël Heinzer, James E Hixson, Georg Homuth, M Arfan Ikram, Pirjo Komulainen, Jose E Krieger, Jiwon Lee, Jingmin Liu, Kurt K Lohman, Annemarie I Luik, Reedik Mägi, Lisa W Martin, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Mike A Nalls, Jeff O'Connell, Annette Peters, Patricia Peyser, Olli T Raitakari, Alex P Reiner, Patrick C N Rensen, Treva K Rice, Stephen S Rich, Till Roenneberg, Jerome I Rotter, Pamela J Schreiner, James Shikany, Stephen S Sidney, Mario Sims, Colleen M Sitlani, Tamar Sofer, Konstantin Strauch, Morris A Swertz, Kent D Taylor, André G Uitterlinden, Cornelia M van Duijn, Henry Völzke, Melanie Waldenberger, Robert B Wallance, Ko Willems van Dijk, Caizheng Yu, Alan B Zonderman, Diane M Becker, Paul Elliott, Tõnu Esko, Christian Gieger, Hans J Grabe, Timo A Lakka, Terho Lehtimäki, Kari E North, Brenda W J H Penninx, Peter Vollenweider, Lynne E Wagenknecht, Tangchun Wu, Yong-Bing Xiang, Wei Zheng, Donna K Arnett, Claude Bouchard, Michele K Evans, Vilmundur Gudnason, Sharon Kardia, Tanika N Kelly, Stephen B Kritchevsky, Ruth J F Loos, Alexandre C Pereira, Mike Province, Bruce M Psaty, Charles Rotimi, Xiaofeng Zhu, Najaf Amin, L Adrienne Cupples, Myriam Fornage, Ervin F Fox, Xiuqing Guo, W James Gauderman, Kenneth Rice, Charles Kooperberg, Patricia B Munroe, Ching-Ti Liu, Alanna C Morrison, Dabeeru C Rao, Diana van Heemst, Susan Redline,

Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ancestry genome-wide sleep-SNP interaction analyses on three lipid traits (HDL-c, LDL-c and triglycerides). In the total study sample (discovery + replication) of 126,926 individuals ... Read more >>

Nat Commun (Nature communications)
[2019, 10(1):5121]

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Nurses' Sleepiness and Sleeplessness: The Epidemic of Insufficient Sleep.

Patti Rager Zuzelo,

Holist Nurs Pract (Holistic nursing practice)
[2018, 32(3):172-174]

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Workplace Interventions to Promote Sleep Health and an Alert, Healthy Workforce.

Nancy S Redeker, Claire C Caruso, Sarah D Hashmi, Janet M Mullington, Michael Grandner, Timothy I Morgenthaler,

STUDY OBJECTIVES:The purpose of this review is to synthesize the published literature that addresses employer-initiated interventions to improve the sleep of workers and in turn improve health, productivity, absenteeism, and other outcomes that have been associated with sleep disorders or sleep deficiency. METHODS:We conducted a systematic search and a selective ... Read more >>

J Clin Sleep Med (Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine)
[2019, 15(4):649-657]

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Editorial Perspective: Delayed circadian rhythm phase: a cause of late-onset attention-deficit/hyperactivity disorder among adolescents?

Jessica R Lunsford-Avery, Scott H Kollins,

Late-onset attention-deficit/hyperactivity disorder (ADHD) has been a topic of significant debate within our field. One question focuses on whether there may be alternative explanations for the onset of inattentive and/or hyperactive symptoms in adolescence. Adolescence is a developmental period associated with a normative circadian rhythm phase delay, and there is ... Read more >>

J Child Psychol Psychiatry (Journal of child psychology and psychiatry, and allied disciplines)
[2018, 59(12):1248-1251]

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Towards an Evolutionary View of Bipolar Disorders.

Antonio E Nardi,

Clin Pract Epidemiol Ment Health (Clinical practice and epidemiology in mental health : CP & EMH)
[2018, 14:233-235]

Cited: 0 times

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Sleep Problems and Workplace Violence: A Systematic Review and Meta-Analysis.

Nicola Magnavita, Enrico Di Stasio, Ilaria Capitanelli, Erika Alessandra Lops, Francesco Chirico, Sergio Garbarino,

Background: This systematic review with meta-analysis was carried out to study the relationship between workplace violence and sleep problems. Methods: The PRISMA statement was used to conduct a systematic search of the literature on PubMed/MEDLINE, Scopus, Sociological abstract, DOAJ, Web of Science, and Google Scholar databases. Of the original number ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2019, 13:997]

Cited: 1 time

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A bidirectional relationship between sleep and oxidative stress in Drosophila.

Vanessa M Hill, Reed M O'Connor, Gunter B Sissoko, Ifeoma S Irobunda, Stephen Leong, Julie C Canman, Nicholas Stavropoulos, Mimi Shirasu-Hiza,

Although sleep appears to be broadly conserved in animals, the physiological functions of sleep remain unclear. In this study, we sought to identify a physiological defect common to a diverse group of short-sleeping Drosophila mutants, which might provide insight into the function and regulation of sleep. We found that these ... Read more >>

PLoS Biol. (PLoS biology)
[2018, 16(7):e2005206]

Cited: 6 times

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A Drosophila model of sleep restriction therapy for insomnia.

Samuel J Belfer, Alexander G Bashaw, Michael L Perlis, Matthew S Kayser,

Insomnia is the most common sleep disorder among adults, especially affecting individuals of advanced age or with neurodegenerative disease. Insomnia is also a common comorbidity across psychiatric disorders. Cognitive behavioral therapy for insomnia (CBT-I) is the first-line treatment for insomnia; a key component of this intervention is restriction of sleep ... Read more >>

Mol. Psychiatry (Molecular psychiatry)
[2019, :]

Cited: 0 times

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Efficacy of melatonin on sleep quality after laparoscopic cholecystectomy.

Vaibhav Vij, Divya Dahiya, Lileswar Kaman, Arunanshu Behera,

CONTEXT:Postoperative sleep and circadian rhythm disturbances were associated with prolonged postoperative convalescence, respiratory, and cardiovascular morbidity. Sleep disturbances have been shown to be due to decreased levels of circulating melatonin after surgery. If this sleep pattern and circadian rhythm are recycled, outcome after surgery could be improved. AIMS:The aim of ... Read more >>

Indian J Pharmacol (Indian journal of pharmacology)
[2018, 50(5):236-241]

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