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Shock and Hypotension in the Newborn

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Neonatal functional echocardiography.

Cecile Tissot, Yogen Singh,

PURPOSE OF REVIEW:The role of echocardiography has dramatically changed over the past decade and use of functional echocardiography has become increasingly popular among neonatologists and pediatric intensivists in making clinical decisions in sick infants and children. The purpose of this review is to outline the current capabilities and limitations of ... Read more >>

Curr. Opin. Pediatr. (Current opinion in pediatrics)
[2020, 32(2):235-244]

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Anaphylaxis: Ten-year retrospective study from a tertiary-care hospital in Asia.

Pisuttikan Rangkakulnuwat, Krongkarn Sutham, Mongkol Lao-Araya,

BACKGROUND:The study of anaphylaxis in different geographic areas raises the awareness to improve prevention and medical care. OBJECTIVE:To investigate the incidence, causes, characteristics, and management of anaphylaxis in Chiang Mai, Thailand. METHODS:We performed a retrospective review, based on ICD-10 electronic medical records of patients who attended the Out-Patient and Emergency ... Read more >>

Asian Pac. J. Allergy Immunol. (Asian Pacific journal of allergy and immunology)
[2020, 38(1):31-39]

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ECMO for Neonatal Sepsis in 2019.

Warwick Wolf Butt, Roberto Chiletti,

Sepsis and septic shock in newborns causes mortality and morbidity depending on the organism and primary site. ECMO provides cardiorespiratory support to allow adequate organ perfusion during the time for antibiotics and source control surgery (if needed) to occur. ECMO mode and cannulation site vary depending on support required and ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:50]

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Rare cause of emergency in the first week of life: congenital hepatoblastoma (case report).

Gloria Ha Young Yoo, Veronica Mugarab-Samedi, Gregory Hansen, Grant Miller, Laurence Givelichian, Kaarthigeyan Kalaniti, Sibasis Daspal,

During the first week of life, a sudden deterioration in a newborn commonly includes investigations to rule out infections, lung pathologies, cardiac lesions, neurological insults, metabolic disorders or gastrointestinal emergencies. It is unusual, however, to consider malignancy as the primary causative factor. In this case report, we describe a rare ... Read more >>

Oxf Med Case Reports (Oxford medical case reports)
[2020, 2020(2):omaa002]

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Mepivacaine-induced anaphylactic shock in a pregnant woman undergoing combined spinal and epidural anesthesia for cesarean delivery: a case report.

Miyuki Takahashi, Kunihisa Hotta, Soichiro Inoue, Tomonori Takazawa, Tatsuo Horiuchi, Takashi Igarashi, Mamoru Takeuchi,

BACKGROUND:Anaphylactic shock during pregnancy is a rare but life-threatening event for both the mother and the newborn. CASE PRESENTATION:A 42-year-old woman, who was pregnant with twins, was scheduled for cesarean delivery under combined spinal and epidural anesthesia. An epidural catheter was placed uneventfully. After spinal anesthesia, the patient exhibited skin ... Read more >>

JA Clin Rep (JA clinical reports)
[2019, 5(1):84]

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Hemodynamic effects of intravenous paracetamol in critically ill children with septic shock on inotropic support.

Elhanan Nahum, Avichai Weissbach, Eytan Kaplan, Gili Kadmon,

Background:Treatment with intravenous paracetamol may impair hemodynamics in critically ill adults. Few data are available in children. The aim of this study was to investigate the frequency, extent, and risk factors of hypotension following intravenous paracetamol administration in children with septic shock on inotropic support. Methods:We retrospectively reviewed the electronic ... Read more >>

J Intensive Care (Journal of Intensive Care)
[2020, 8:14]

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Prevalence and Management of Septic Shock among Children Admitted at the Kenyatta National Hospital, Longitudinal Survey.

Varsha Vekaria-Hirani, Rashmi Kumar, Rachel N Musoke, Ezekiel M Wafula, Idris N Chipkophe,

Background:Paediatric septic shock is a subset of sepsis associated with high mortality. Implementing the existing international Surviving Sepsis Campaign Guidelines 2012 (SSCG) have contributed to reduction of mortality in many places but these have not been adopted in our setting. The current study aimed at documenting the practice at a ... Read more >>

Int J Pediatr (International journal of pediatrics)
[2019, 2019:1502963]

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Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing Cesarean delivery: a case series of 17 patients.

Rong Chen, Yuan Zhang, Lei Huang, Bi-Heng Cheng, Zhong-Yuan Xia, Qing-Tao Meng,

PURPOSE:To assess the management and safety of epidural or general anesthesia for Cesarean delivery in parturients with coronavirus disease (COVID-19) and their newborns, and to evaluate the standardized procedures for protecting medical staff. METHODS:We retrospectively reviewed the cases of parturients diagnosed with severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection disease ... Read more >>

Can J Anaesth (Canadian Journal of Anaesthesia)
[2020, :]

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Neonatologist performed echocardiography (NPE) in Italian neonatal intensive care units: a national survey.

Iuri Corsini, Benjamim Ficial, Stefano Fiocchi, Federico Schena, Irma Capolupo, Rosa Maria Cerbo, Manuela Condò, Daniela Doni, Simona La Placa, Salvatore Porzio, Katia Rossi, Sabrina Salvadori, Marilena Savoia, ,

BACKGROUND:Neonatologist performed echocardiography (NPE) has increasingly been used to assess the hemodynamic status in neonates. Aim of this survey was to investigate the utilization of NPE in Italian neonatal intensive care units (NICUs). METHODS:We conducted an on-line survey from June to September 2017. A questionnaire was developed by the Italian ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2019, 45(1):131]

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Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children.

Scott L Weiss, Mark J Peters, Waleed Alhazzani, Michael S D Agus, Heidi R Flori, David P Inwald, Simon Nadel, Luregn J Schlapbach, Robert C Tasker, Andrew C Argent, Joe Brierley, Joseph Carcillo, Enitan D Carrol, Christopher L Carroll, Ira M Cheifetz, Karen Choong, Jeffry J Cies, Andrea T Cruz, Daniele De Luca, Akash Deep, Saul N Faust, Claudio Flauzino De Oliveira, Mark W Hall, Paul Ishimine, Etienne Javouhey, Koen F M Joosten, Poonam Joshi, Oliver Karam, Martin C J Kneyber, Joris Lemson, Graeme MacLaren, Nilesh M Mehta, Morten Hylander Møller, Christopher J L Newth, Trung C Nguyen, Akira Nishisaki, Mark E Nunnally, Margaret M Parker, Raina M Paul, Adrienne G Randolph, Suchitra Ranjit, Lewis H Romer, Halden F Scott, Lyvonne N Tume, Judy T Verger, Eric A Williams, Joshua Wolf, Hector R Wong, Jerry J Zimmerman, Niranjan Kissoon, Pierre Tissieres,

OBJECTIVES:To develop evidence-based recommendations for clinicians caring for children (including infants, school-aged children, and adolescents) with septic shock and other sepsis-associated organ dysfunction. DESIGN:A panel of 49 international experts, representing 12 international organizations, as well as three methodologists and three public members was convened. Panel members assembled at key international ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(Suppl 1):10-67]

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Sepsis Care Pathway 2019.

Ahmed Labib,

Background: Sepsis, a medical emergency and life-threatening disorder, results from abnormal host response to infection that leads to acute organ dysfunction1. Sepsis is a major killer across all ages and countries and remains the most common cause of admission and death in the Intensive Care Unit (ICU)2. The true incidence ... Read more >>

Qatar Med J (Qatar medical journal)
[2019, 2019(2):4]

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Amniotic Fluid Embolism Treated with Veno-Arterial Extracorporeal Membrane Oxygenation.

Robert Gitman, Bradlee Bachar, Byron Mendenhall,

Amniotic fluid embolism (AFE) is an extremely rare yet fatal obstetric emergency. AFE presents as sudden cardiovascular collapse after a breach of maternal-fetal membranes and is often complicated by severe coagulopathy. We present a case where an AFE was treated with veno-arterial extracorporeal membrane oxygenation (ECMO) to help overcome the ... Read more >>

Case Rep Crit Care (Case reports in critical care)
[2019, 2019:4589636]

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Plasma B-type natriuretic peptide cannot predict treatment response to ibuprofen in preterm infants with patent ductus arteriosus.

Seong Hee Oh, Byong Sop Lee, Euiseok Jung, Moon Yeon Oh, Hyun-Jeong Do, Ellen Ai-Rhan Kim, Ki-Soo Kim,

Plasma B-type natriuretic peptide (BNP) is a useful marker for diagnosis of hemodynamically significant PDA (hsPDA) and serial BNP measurement is also valuable for monitoring treatment response. This retrospective study was performed to evaluate whether plasma BNP level can predict treatment response to ibuprofen in preterm infants born at <30 ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):4430]

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Postpartum histoplasmosis in an HIV-negative woman: a case report and phylogenetic characterization by internal transcribed spacer region analysis.

Lisandra Serra Damasceno, Antônio Mauro Barros Almeida Júnior, Bárbara de Oliveira Aguiar, Mauro de Medeiros Muniz, Marcos de Abreu Almeida, Rosely Maria Zancopé-Oliveira, Terezinha do Menino Jesus Silva Leitão,

The present report describes the first case of postpartum disseminated histoplasmosis in a 24-year-old HIV-negative woman. On the tenth day after vaginal delivery, the patient presented with dyspnea, fever, hypotension, tachycardia, and painful hepatomegaly. Yeast-like Histoplasma capsulatum features were isolated in the buffy coat. The phylogenetic analysis demonstrated that the ... Read more >>

Rev. Soc. Bras. Med. Trop. (Revista da Sociedade Brasileira de Medicina Tropical)
[2020, 53:e20190364]

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Preoperative adrenal insufficiency in a neonate with congenital heart disease surgery.

Shankar Vithalrao Kadam, Kamlesh B Tailor, Vinay Hk Joshi, Suresh G Rao,

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2019, 12(3):351-353]

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A Global View of Neonatal Asphyxia and Resuscitation.

Robert Moshiro, Paschal Mdoe, Jeffrey M Perlman,

Birth asphyxia (BA), assumed to be related to intrapartum related hypoxia-ischemia, accounts for one million neonatal deaths annually. In the low resource setting BA is usually defined as a failure to initiate or sustain spontaneous breathing at birth. In the resource replete setting BA is a biochemical definition related to ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:489]

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Late-onset glucocorticoid-responsive circulatory collapse in premature infants.

Shigeo Iijima,

Late-onset glucocorticoid-responsive circulatory collapse (LGCC) in infants is characterized by sudden onset of hypotension and/or oliguria, which is resistant to volume expanders and inotropes but responds rapidly to intravenous glucocorticoids. LGCC occurs after the first week of life mainly in relatively stable very low birth weight (VLBW) infants. In Japan, ... Read more >>

Pediatr Neonatol (Pediatrics and neonatology)
[2019, 60(6):603-610]

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Anesthetic management of a patient with Sheehan's syndrome and twin pregnancy while undergoing a cesarean section.

G Arora, N Sahni,

Sheehan's syndrome (SS) is caused by infarction of the pituitary gland usually precipitated by hypotension due to massive uterine hemorrhage during the peripartum period. Once SS develops, it becomes a major comorbidity for the young females and predisposes them to further medical, obstetric, and anesthetic complications. Herein, we report the ... Read more >>

J Postgrad Med (Journal of postgraduate medicine)
[2020, 66(1):51-53]

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Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections.

David A Schwartz, Ashley L Graham,

In early December 2019 a cluster of cases of pneumonia of unknown cause was identified in Wuhan, a city of 11 million persons in the People's Republic of China. Further investigation revealed these cases to result from infection with a newly identified coronavirus, termed the 2019-nCoV. The infection moved rapidly ... Read more >>

Viruses (Viruses)
[2020, 12(2):]

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A comparison of clinical paediatric guidelines for hypotension with population-based lower centiles: a systematic review.

Nienke N Hagedoorn, Joany M Zachariasse, Henriette A Moll,

BACKGROUND:Different definitions exist for hypotension in children. In this study, we aim to identify evidence-based reference values for low blood pressure and to compare these with existing definitions for systolic hypotension. METHODS:We searched online databases until February 2019 (including MEDLINE, EMBASE, Web of Science) using a comprehensive search strategy to ... Read more >>

Crit Care (Critical care (London, England))
[2019, 23(1):380]

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Beyond Anesthesia Toxicity: Anesthetic Considerations to Lessen the Risk of Neonatal Neurological Injury.

Mary Ellen McCann, Jennifer K Lee, Terrie Inder,

Infants who undergo surgical procedures in the first few months of life are at a higher risk of death or subsequent neurodevelopmental abnormalities. Although the pathogenesis of these outcomes is multifactorial, an understanding of the nature and pathogenesis of brain injury in these infants may assist the anesthesiologist in consideration ... Read more >>

Anesth. Analg. (Anesthesia and analgesia)
[2019, 129(5):1354-1364]

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Pediatrics and GUCHs.

J Arrhythm (Journal of Arrhythmia)
[2019, 35(Suppl 1):693-711]

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Corticotrophin-releasing hormone stimulation tests in late-onset circulatory collapse.

Hiroko Ueda, Hiroki Kakita, Shintaro Ichimura, Mari Mori, Satoru Takeshita, Tatenobu Goto, Tomoko Kondo, Yasumasa Yamada,

BACKGROUND:Late-onset circulatory collapse (LCC) is the transient development of refractory hypotension and oliguria after the early neonatal period, which may cause periventricular leukomalacia (PVL). The aim of this study was to evaluate the endogenous cortisol response to corticotrophin-releasing hormone (CRH) and determine whether it is effective for elucidating the pathology ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2019, 61(11):1114-1119]

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Sepsis: Precision-Based Medicine for Pregnancy and the Puerperium.

Orene Greer, Nishel Mohan Shah, Shiranee Sriskandan, Mark R Johnson,

Sepsis contributes significantly to global morbidity and mortality, particularly in vulnerable populations. Pregnant and recently pregnant women are particularly prone to rapid progression to sepsis and septic shock, with 11% of maternal deaths worldwide being attributed to sepsis. The impact on the neonate is considerable, with 1 million neonatal deaths ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(21):]

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Journal of Clinical Monitoring and Computing end of year summary 2019: hemodynamic monitoring and management.

Bernd Saugel, Lester A H Critchley, Thomas Kaufmann, Moritz Flick, Karim Kouz, Simon T Vistisen, Thomas W L Scheeren,

J Clin Monit Comput (Journal of clinical monitoring and computing)
[2020, 34(2):207-219]

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