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Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants.

Fengze Wang, Li Li, Yang Dou, Rui Shi, Xiaomin Duan, Hongchuan Liu, Jing Zhang, DanDan Liu, Jing Wu, Yang He, Jun Lan, Bai Lu, Hui Feng, Jinghua Yan,

The neutralizing antibody is a potential therapeutic for the ongoing COVID-19 pandemic. As an antiviral agent, numerous mAbs recognize the epitopes that overlap with ACE2-binding sites in the SARS-CoV-2-RBD. Some studies have shown that residual changes on the spike protein can significantly decrease the efficiency of neutralizing antibodies. To address ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2022, 11(1):548-551]

Cited: 2 times

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Bat coronaviruses related to SARS-CoV-2: what about their 3CL proteases (MPro)?

Matteo Pavan, Davide Bassani, Mattia Sturlese, Stefano Moro,

Despite a huge effort by the scientific community to determine the animal reservoir of SARS-CoV-2, which led to the identification of several SARS-CoV-2-related viruses both in bats and in pangolins, the origin of SARS-CoV-2 is still not clear. Recently, Temmam et al. reported the discovery of bat coronaviruses with a high ... Read more >>

J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2022, 37(1):1077-1082]

Cited: 0 times

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