Full Text Journal Articles about
Restrictive Lung Disease

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Adult outcomes of childhood bronchiectasis.

Dawn Sibanda, Rosalyn Singleton, John Clark, Christine Desnoyers, Ellen Hodges, Gretchen Day, Gregory Redding,

Recent literature has highlighted the importance of transition from paediatric to adult care for children with chronic conditions. Non-cystic fibrosis bronchiectasis is an important cause of respiratory morbidity in low-income countries and in indigenous children from affluent countries; however, there is little information about adult outcomes of childhood bronchiectasis. We ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2020, 79(1):1731059]

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Pectoralis muscle area is associated with bone mineral density and lung function in lung transplant candidates.

A D Parulekar, T Wang, G W Li, V Hoang, C C Kao,

Loss of bone mineral density and skeletal muscle area are linked in lung transplant patients. This loss is greater in patients with restrictive compared with obstructive lung diseases. INTRODUCTION:Sarcopenia and osteoporosis are associated with aging and chronic illnesses and may be linked in patients with advanced lung disease. Pectoralis muscle ... Read more >>

Osteoporos Int (Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA)
[2020, :]

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Restrictive spirometric pattern and true pulmonary restriction in a general population sample aged 50 - 64 years.

Kjell Torén, Linus Schiöler, Jonas Brisman, Andrei Malinovschi, Anna-Carin Olin, Göran Bergström, Björn Bake,

BACKGROUND:There is low diagnostic accuracy of the proxy restrictive spirometric pattern (RSP) to identify true pulmonary restriction. This knowledge is based on patients referred for spirometry and total lung volume determination by plethysmograpy, single breath nitrogen washout technique or gas dilution and selected controls. There is, however, a lack of ... Read more >>

BMC Pulm Med (BMC pulmonary medicine)
[2020, 20(1):55]

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Persistence and Progression of Airway Obstruction in Children With Early Onset Scoliosis.

Gregory J Redding, Heidi Hurn, Klane K White, Viviana Bompadre, Julia Emerson, R Zachary Garza, Kendall Anigian, John Waldhausen, Walter Krengel, Ajeya Joshi,

BACKGROUND:Obstructive lung disease occurs in 30% of children with early onset scoliosis (EOS); changes in degree of airway obstruction over time have not been reported. METHODS:Longitudinal patterns of incidental, persistent, and progressive airway obstruction were retrospectively analyzed in a cohort of children with EOS with at least 1 forced expiratory ... Read more >>

J Pediatr Orthop (Journal of pediatric orthopedics)
[2020, 40(4):190-195]

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The Association Between Lung Function and Type 2 Diabetes in Koreans.

Do-Youn Lee, Seung-Min Nam,

Objectives:This study was performed to test the association between lung function and type 2 diabetes mellitus (T2DM) in Korean patients. Methods:Data from the 6th Korea National Health and Nutrition Examination Survey (2013 to 2015) was used in this study. There were 3,466 individuals aged between 40 and 80 years, with ... Read more >>

Osong Public Health Res Perspect (Osong public health and research perspectives)
[2020, 11(1):27-33]

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Dietary alterations modulate the microRNA 29/30 and IGF-1/AKT signaling axis in breast Cancer liver metastasis.

Anuradha A Shastri, Anthony Saleh, Jason E Savage, Tiziana DeAngelis, Kevin Camphausen, Nicole L Simone,

Background:Metastatic cancer is incurable and understanding the molecular underpinnings is crucial to improving survival for our patients. The IGF-1/Akt signaling pathway is often impaired in cancer leading to its progression and metastases. Diet modification is known to alter the IGF-1/Akt pathway and affect the expression of microRNA involved in tumor ... Read more >>

Nutr Metab (Lond) (Nutrition & metabolism)
[2020, 17:23]

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Therapist Driven Rehabilitation Protocol for Patients with Chronic Heart and Lung Diseases: A Real-Life Study.

Carla Simonelli, Michele Vitacca, Nicolino Ambrosino, Simonetta Scalvini, Francesca Rivadossi, Manuela Saleri, Aubin G Fokom, Ilaria Speltoni, Riccardo Ghirardi, Mara Paneroni,

Therapist driven protocols may help to tailor rehabilitation programs to individual patients. We aimed to test the feasibility, safety, and clinical usefulness of a therapist driven protocol for rehabilitation including exercise training of patients with heart or lung diseases. An internal audit elaborated the Cardio-Respiratory Exercise Maugeri Algorithm (CREMA) based ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(3):]

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Relationship between pulmonary function, throw distance, and psychological competitive ability of elite highly trained Japanese boccia players via correlation analysis.

Tomomi Ichiba, Kuniharu Okuda, Tetsuo Miyagawa, Masataka Kataoka, Kousuke Yahagi,

Background:Boccia players have severe quadriplegia; nonetheless, detailed aspects of the physical function of individual players have not been evaluated. Aims:This study aimed to detetmine the relationship between pulmonary function, pitching distance, and psychological competitive ability of Japanese boccia players. Methods:Participants were athletes from the Japan Boccia Association (10 males, 3 ... Read more >>

Heliyon (Heliyon)
[2020, 6(3):e03581]

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Does lung function predict the risk of disability pension? An 11-year register-based follow-up study.

Irmeli Lindström, Paula Pallasaho, Jouko Remes, Tuula Vasankari, Markku Heliövaara,

BACKGROUND:Spirometry is widely used in medical surveillance in occupational health and as a diagnostic test for obstructive and restrictive lung disease. We evaluated the effect of spirometry parameters on the risk of all-cause disability pension in a follow-up study of an occupationally active general population-based cohort. METHODS:We measured the pulmonary ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):165]

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Continued growth of locally aggressive fibrous dysplasia of 22 years duration after reaching adulthood: a case report.

Yusuke Yamagishi, Masanori Okamoto, Yasuo Yoshimura, Munehisa Kito, Kaoru Aoki, Jun Takahashi,

Fibrous dysplasia generally stops growing when patients reach adulthood. Locally aggressive fibrous dysplasia is an extremely rare subtype of fibrous dysplasia that is characterized by progressive enlargement after bone maturation, cortical bone destruction and soft tissue invasion but without malignant transformation. At 50 years of age, a tumor was found in ... Read more >>

J Surg Case Rep (Journal of Surgical Case Reports)
[2020, 2020(2):rjz406]

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Clinical exome sequencing revealed that FLNC variants contribute to the early diagnosis of cardiomyopathies in infant patients.

Feifan Xiao, Qiufen Wei, Bingbing Wu, Xu Liu, Aiyao Mading, Lin Yang, Yan Li, Fang Liu, Xinnian Pan, Huijun Wang,

Background:FLNC encodes actin-binding protein and is mainly concentrated in skeletal and cardiac muscle. Mutations in FLNC were found in cardiomyopathies. To date, studies on FLNC-cardiomyopathies have mainly been reported in adults. There are limited studies that have investigated FLNC variants in pediatric patients with cardiomyopathies. Methods:We summarized the patients who ... Read more >>

Transl Pediatr (Translational pediatrics)
[2020, 9(1):21-33]

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Spontaneous Chylothorax following Septic Pulmonary Embolization.

Michael Agustin, Michele Yamamoto, Chawat Tongma, Leslie Anne Chua, Michael Torres, Scott Shay,

Chylothorax is the occurrence of chyle (lymph) in the pleural cavity secondary to damage of the thoracic duct. It is a rare form of pleural effusion which appears as a milky white turbid fluid. Malignancy is the leading cause of nontraumatic chylothorax while inadvertent surgical injury to the thoracic duct ... Read more >>

Case Rep Pulmonol (Case reports in pulmonology)
[2020, 2020:3979507]

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Risk stratification of pulmonary toxicities in the combination of whole lung irradiation and high-dose chemotherapy for Ewing sarcoma patients with lung metastases: a review.

Sergiu Scobioala, Hans Theodor Eich,

BACKGROUND:Whole lung irradiation (WLI) represents an important part of multimodal therapy in Ewing sarcoma (EwS) patients diagnosed with pulmonary metastases. This review discusses pulmonary toxicity in EwS patients with pulmonary metastases treated with WLI, who received different modes of high-dose chemotheray (HD-Cth). METHODS:Literature was compiled using the Cochrane Library, PubMed ... Read more >>

Strahlenther Onkol (Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al])
[2020, :]

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Bench investigation of the accuracy of the dynamic approach in respiratory mechanics during noninvasive ventilation with different pressure support levels

Yuqing Chen, Yueyang Yuan, Hai Zhang, Feng Li, Xin Zhou,

<title>Abstract</title> <p> <bold>Background:</bold> Under the dynamic conditions of non-invasive mechanical ventilation, respiratory system mechanics parameters, including compliance (C<sub>rs</sub>) and airway resistance (R<sub>rs</sub>), are affected by systemic and ventilator parameters. We evaluated the accuracy of respiratory mechanics in the dynamic approach in different lung disease models during pressure support ... Read more >>

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Initial combination therapy of ambrisentan and tadalafil in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) in the modified intention-to-treat population of the AMBITION study: post hoc analysis.

Masataka Kuwana, Christiana Blair, Tomohiko Takahashi, Jonathan Langley, John G Coghlan,

OBJECTIVES:To evaluate initial combination therapy with ambrisentan plus tadalafil (COMB) compared with monotherapy of either agent (MONO), and the utility of baseline characteristics and risk stratification in predicting outcomes, in patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) and the systemic sclerosis (SSc)-pulmonary arterial hypertension (PAH) subpopulation. METHODS:This post ... Read more >>

Ann. Rheum. Dis. (Annals of the rheumatic diseases)
[2020, :]

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Polymyalgia Rheumatica (PMR) and Lung Involvement: The Forgotten Association.

Hoda Mohamed Bakri Hammoda, Jamal Al Saleh, Kathija Mahmood, Ola Abdel Hamid Moustafa Darwish, Mohamed Elfadil Abdelrahman Musa, Manal Sayed Rezzek,

Polymyalgia rheumatica (PMR) is an inflammatory condition of unknown etiology, commonly occurring in the elderly and is associated with a good prognosis. Patients usually present with pain in the neck, shoulders, and hips. The onset is often abrupt and is associated with depression and flu-like symptoms. Lung involvement in patients ... Read more >>

Oman Med J (Oman medical journal)
[2020, 35(2):e105]

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Office Spirometry: Indications and Interpretation.

Robert C Langan, Andrew J Goodbred,

High-quality, office-based spirometry provides diagnostic information as useful and reliable as testing performed in a pulmonary function laboratory. Spirometry may be used to monitor progression of lung disease and response to therapy. A stepwise approach to spirometry allows for ease and reliability of interpretation. Airway obstruction is suspected when there ... Read more >>

Am Fam Physician (American family physician)
[2020, 101(6):362-368]

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Pulmonary manifestations of systemic karyomegaly.

Levent M Akyürek, Aziz Hussein, Andrew G Nicholson, Nils-Johan Mauritz, Johan Mölne,

Over 40 years ago, abnormal enlargement of the nucleus of tubular epithelial cells was reported in a rare distinct hereditary chronic interstitial nephritis, karyomegalic interstitial nephritis (KIN). Here, we report the second case of systemic karyomegaly with pulmonary manifestations and present a detailed characterization of the karyomegalic cells in lung ... Read more >>

Respir Med Case Rep (Respiratory medicine case reports)
[2020, 29:101032]

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Spirometry results after treatment for pulmonary tuberculosis: comparison between patients with and without previous lung disease: a multicenter study.

Eliane Viana Mancuzo, Eduardo Martins Netto, Nara Sulmonett, Vanessa de Souza Viana, Júlio Croda, Afranio Lineu Kritski, Fernanda Carvalho de Queiroz Mello, Simone de Souza Elias Nihues, Karen Rosas Sodre Azevedo, Silvana Spíndola de Miranda,

OBJECTIVE:To compare patients with and without previous lung disease, in terms of the spirometry results after they had been treated for pulmonary tuberculosis (PTB) and cured, as well as to analyze risk factors related to functional severity. METHODS:This was a cross-sectional, multicenter study conducted at four referral centers in Brazil. ... Read more >>

J Bras Pneumol (Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia)
[2020, 46(2):e20180198]

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Imaging indications and findings in evaluation of lung transplant graft dysfunction and rejection.

Mnahi Bin Saeedan, Sanjay Mukhopadhyay, C Randall Lane, Rahul D Renapurkar,

Lung transplantation is a treatment option in end-stage lung disease. Complications can develop along a continuum in the immediate or longer post-transplant period, including surgical and technical complications, primary graft dysfunction, rejection, infections, post-transplant lymphoproliferative disorder, and recurrence of the primary disease. These complications have overlapping clinical and imaging features ... Read more >>

Insights Imaging (Insights into imaging)
[2020, 11(1):2]

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A case report on transient global ventricular wall thickening secondary to acute myocarditis: Focus on the unique role of cardiac MRI.

Tiantian Xu, Hongjie Hu,

INTRODUCTION:Transient left ventricular wall thickening is known to develop in the acute phase of myocarditis, with several reports documenting this unusual mode of myocarditis. Diagnosing myocarditis can be challenging because symptoms, clinical exam findings, electrocardiogram results, biomarkers, and echocardiogram results are often non-specific. Therefore, cardiac magnetic resonance imaging has become ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(8):e19223]

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Association of respiratory function with physical performance, physical activity, and sedentary behavior in older adults.

Hideo Kaneko,

[Purpose] The associations between respiratory function, physical performance, physical activity, and sedentary behavior in older adults remain to be elucidated. This study aimed to investigate the associations of lung volume and respiratory muscle strength with physical performance, physical activity, and sedentary behavior in older adults. [Participants and Methods] In 62 ... Read more >>

J Phys Ther Sci (Journal of physical therapy science)
[2020, 32(2):92-97]

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[Sustainability in Outpatient Pulmonary Rehabilitation in Patients with Asbestosis - Results of an 8-Year Follow Up].

S Dalichau, T Möller,

BACKGROUND: The aim of this study was to evaluate the effects of an outpatient medical rehabilitation (OMR) mainly composed of exercise therapy and sports for patients with asbestosis and focused on keeping up sustainability effects. METHODS: 157 male patients aged 65.2 ± 5.7 years suffering from asbestosis carried out over a period of three ... Read more >>

Pneumologie (Pneumologie (Stuttgart, Germany))
[2020, :]

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Comorbidities and course of lung function in patients with congenital esophageal atresia.

Ana Jové Blanco, Ana Gutiérrez Vélez, Gonzalo Solís-García, Antonio Salcedo Posadas, Sara Bellón Alonso, Juan Luis Rodríguez Cimadevilla,

OBJECTIVE:To describe the epidemiological characteristics, hospital follow-up, and course of patients who underwent surgery for esophageal atresia and its consequences on lung function. POPULATION AND METHODS:Retrospective, longitudinal, and analytical study. The medical records of patients with esophageal atresia born between 1996 and 2017 were reviewed. Perinatal data, type of atresia, ... Read more >>

Arch Argent Pediatr (Archivos argentinos de pediatria)
[2020, 118(1):25-30]

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HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma.

Joe Zein, Benjamin Gaston, Peter Bazeley, Mark D DeBoer, Robert P Igo, Eugene R Bleecker, Deborah Meyers, Suzy Comhair, Nadzeya V Marozkina, Calvin Cotton, Mona Patel, Mohammad Alyamani, Weiling Xu, William W Busse, William J Calhoun, Victor Ortega, Gregory A Hawkins, Mario Castro, Kian Fan Chung, John V Fahy, Anne M Fitzpatrick, Elliot Israel, Nizar N Jarjour, Bruce Levy, David T Mauger, Wendy C Moore, Patricia Noel, Stephen P Peters, W Gerald Teague, Sally E Wenzel, Serpil C Erzurum, Nima Sharifi,

Asthma resistance to glucocorticoid treatment is a major health problem with unclear etiology. Glucocorticoids inhibit adrenal androgen production. However, androgens have potential benefits in asthma. HSD3B1 encodes for 3β-hydroxysteroid dehydrogenase-1 (3β-HSD1), which catalyzes peripheral conversion from adrenal dehydroepiandrosterone (DHEA) to potent androgens and has a germline missense-encoding polymorphism. The adrenal ... Read more >>

Proc. Natl. Acad. Sci. U.S.A. (Proceedings of the National Academy of Sciences of the United States of America)
[2020, 117(4):2187-2193]

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