Full Text Journal Articles about
Recurrent Respiratory Papillomatosis

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Altered Monocyte and Langerhans Cell Innate Immunity in Patients With Recurrent Respiratory Papillomatosis (RRP).

Mohd Israr, James A DeVoti, Fung Lam, Allan L Abramson, Bettie M Steinberg, Vincent R Bonagura,

The micromilieu within respiratory papillomas supports persistent human papillomavirus (HPV) infection and disease recurrence in patients with recurrent respiratory papillomatosis (RRP). These patients show polarized (TH2-/Treg) adaptive immunity in papillomas and blood, enriched immature Langerhans cell (iLC) numbers, and overexpression of cyclooxygenase-2/prostaglandin E2 (PGE2) in the upper airway. Blood monocyte-derived, ... Read more >>

Front Immunol (Frontiers in Immunology)
[2020, 11:336]

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Juvenile-Onset Recurrent Respiratory Papillomatosis Diagnosis and Management - A Developing Country Review.

R Y Seedat,

Recurrent respiratory papillomatosis (RRP) is a condition caused by human papillomavirus (HPV), usually HPV types 6 and 11, which is characterized by recurrent papillomas of the respiratory tract, mainly the larynx. Patients usually present between the ages of 2 and 6 years. The initial presenting symptom is progressive dysphonia, followed ... Read more >>

Pediatric Health Med Ther (Pediatric health, medicine and therapeutics)
[2020, 11:39-46]

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Use of intralesional cidofovir in the recurrent respiratory papillomatosis: a review of the literature.

F Gazia, B Galletti, F Freni, R Bruno, F Sireci, C Galletti, A Meduri, F Galletti,

OBJECTIVE:Recurrent respiratory papillomatosis (RRP) is characterized by exophytic, benign, and papillary lesions infected by the virus in the epithelium of the upper aerodigestive tract. RRP is caused by persistent infection of the respiratory epithelium by human papillomavirus (HPV) HPV6 and-11. The clinical course of RRP is unpredictable, frequently relapsing, and ... Read more >>

Eur Rev Med Pharmacol Sci (European review for medical and pharmacological sciences)
[2020, 24(2):956-962]

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Immune Therapy Targeting E6/E7 Oncogenes of Human Paillomavirus Type 6 (HPV-6) Reduces or Eliminates the Need for Surgical Intervention in the Treatment of HPV-6 Associated Recurrent Respiratory Papillomatosis.

Charu Aggarwal, Roger B Cohen, Matthew P Morrow, Kimberly A Kraynyak, Albert J Sylvester, Jocelyn Cheung, Kelsie Dickerson, Veronique Schulten, Dawson Knoblock, Elisabeth Gillespie, Joshua M Bauml, Jian Yan, Malissa Diehl, Jean Boyer, Michael Dallas, J Joseph Kim, David B Weiner, Jeffrey M Skolnik,

: Background: Recurrent respiratory papillomatosis (RRP) is a rare disorder characterized by the generation of papillomas of the aerodigestive tract, usually associated with human papilloma virus (HPV) subtypes 6, 11. INO-3106 is a DNA plasmid-based immunotherapy targeting E6 and E7 proteins of HPV6, in order to create a robust immune ... Read more >>

Vaccines (Basel) (Vaccines)
[2020, 8(1):]

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Laryngotracheobronchial papillomatosis: an uncommon cause of recurrent respiratory infection.

Bruno Niemeyer de Freitas Ribeiro, Edson Marchiori,

Rev. Soc. Bras. Med. Trop. (Revista da Sociedade Brasileira de Medicina Tropical)
[2020, 53:e20190441]

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Photodynamic therapy for the treatment of tracheobronchial papillomatosis: a multicenter experience.

Kristen Glisinski, Jonathan S Kurman, Adam Spandorfer, Nicholas J Pastis, Septimiu Murgu, George Z Cheng,

OBJECTIVE:Recurrent respiratory papillomatosis (RRP) causes mucosal wart-like growths of the upper aerodigestive tract, which can undergo malignant transformation. These tumors are difficult to treat, often requiring repeated debridement, which can be associated with high morbidity. Photodynamic therapy (PDT) uses a photosensitizing medication and a topically applied light source to treat ... Read more >>

Photodiagnosis Photodyn Ther (Photodiagnosis and photodynamic therapy)
[2020, :101711]

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Evaluation of Safety of Intralesional Cidofovir for Adjuvant Treatment of Recurrent Respiratory Papillomatosis.

Rebecca C Hoesli, Aaron L Thatcher, Norman D Hogikyan, Robbi A Kupfer,

Importance:The use of intralesional cidofovir injections for recurrent respiratory papillomatosis (RRP) remains controversial owing to concern regarding the risks of its use, including increased risk of dysplasia or carcinogenesis. Objective:To describe the rates of dysplasia, development of malignant lesions, and adverse events associated with use of intralesional cidofovir injections as ... Read more >>

JAMA Otolaryngol Head Neck Surg (JAMA otolaryngology-- head & neck surgery)
[2020, :]

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Role of epstein-barr virus in the severity of recurrent respiratory papillomatosis.

Victor Costa, Vivian Narana El-Achkar, Patrícia Pimentel de Barros, Jorge Esquiche León, Alfredo Ribeiro-Silva, Román Carlos, Shirley Shizue Nagata Pignatari, Silvaneide Ferreira, Barbara Pereira Mello, Laura Sichero, Luisa Lina Villa, Estela Kaminagakura,

OBJECTIVE:The objective was to investigate the prevalence of the Epstein-Barr virus (EBV) and its association with human papilloma virus (HPV) detection, clinicopathological features, and the severity of recurrent respiratory papillomatosis (RRP). METHODS:Cases of juvenile recurrent respiratory papillomatosis (JRRP) (n = 36) and adult recurrent respiratory papillomatosis (ARRP) (n = 44) ... Read more >>

Laryngoscope (The Laryngoscope)
[2019, :]

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Laryngeal sequelae secondary to surgical treatment for recurrent respiratory papillomatosis in children.

M L Scatolini, G Labedz, A Cocciaglia, C G Pérez, M E Nieto, M Rodríguez D Áquila, H A Rodríguez,

OBJECTIVE:to describe the frequency and predictive factors associated with laryngeal scarring caused by surgical treatment of recurrent respiratory papillomatosis (RRP) in children. INTRODUCTION:RRP is an important cause of hoarseness and respiratory obstruction in children. The current standard of care for RRP is the systematic and repetitive surgical interventions. The repetitive ... Read more >>

Int. J. Pediatr. Otorhinolaryngol. (International journal of pediatric otorhinolaryngology)
[2020, 130:109815]

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Vocal cord surgery and pharmacological treatment of a patient with HPV and recurrent respiratory papillomatosis.

Francesco Galletti, Francesco Freni, Francesco Gazia, Andrea Gallo,

Recurrent respiratory papillomatosis (RRP) is caused by persistent infection of the respiratory epithelium by human papillomavirus (HPV), especially HPV 6 and 11. We present a case of surgically treated RRP. The main purpose of our protocol is to remove the lesions with a non-aggressive surgical technique and prevent recurrences with ... Read more >>

BMJ Case Rep (BMJ case reports)
[2019, 12(11):]

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Prevention of Human Papillomavirus Infection. Beyond Cervical Cancer: A Brief Review.

Rita Medeiros, Susan Vaz, Teresa Rebelo, Margarida Figueiredo-Dias,

INTRODUCTION:Human papillomavirus is responsible for almost all cases of cervical cancer, an important portion of anogenital and oropharyngeal invasive and preinvasive lesions, as well as genital warts (condyloma acuminatum) and recurrent respiratory papillomatosis. Currently, three prophylactic vaccines against high-risk Human papillomavirus are commercialized in many countries worldwide. METHODS:To this non-systematic ... Read more >>

Acta Med Port (Acta medica portuguesa)
[2020, 33(3):198-201]

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Bevacizumab as adjuvant therapy for recurrent respiratory papillomatosis in an infant.

Christopher Gates, Patrick Tomboc, Andrew Allison, Michele Carr,

Recurrent Respiratory Papillomatosis (RRP) is a benign disease of the airway that can result in symptoms ranging from mild dysphonia to respiratory distress to respiratory failure related to colonization of the lung parenchyma. It is a disease that typically begins in childhood and can require treatment indefinitely, though may remit ... Read more >>

Int. J. Pediatr. Otorhinolaryngol. (International journal of pediatric otorhinolaryngology)
[2020, 129:109762]

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Recurrent pneumothorax, skin lesions and frequent urination.

Kunal Deokar, Ram Niwas, Nishant Chauhan, Naveen Dutt, Priyank Jain, Shahir Asfahan, Rajani Kumawat,

The causes of cystic lung diseases are varied. Proper evaluation is required for appropriate management. http://bit.ly/37J7dvE. ... Read more >>

Breathe (Sheff) (Breathe (Sheffield, England))
[2020, 16(1):190318]

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Symptomatic oral squamous papilloma of the uvula - a rare incidental finding.

K Ramasamy, Y Kanapaty, N Abdul Gani,

Oral squamous papillomas are benign neoplasms of the oral cavity that occur commonly on the palate. Albeit benign and often asymptomatic, they may still cause concern due to their appearance, which may mimic other malignant oral pathologies. Human papillomavirus (HPV) is usually implicated in papilloma pathogenesis. We present a rare ... Read more >>

Malays Fam Physician (Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia)
[2019, 14(3):74-76]

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Immunological tolerance of low-risk HPV in recurrent respiratory papillomatosis.

R Ivancic, H Iqbal, B deSilva, Q Pan, L Matrka,

Recurrent respiratory papillomatosis (RRP) is characterized by benign exophytic lesions of the respiratory tract caused by the human papillomavirus (HPV), in particular low-risk HPV6 and HPV11. Aggressiveness varies greatly among patients. Surgical excision is the current standard of care for RRP, with adjuvant therapy used when surgery cannot control disease ... Read more >>

Clin. Exp. Immunol. (Clinical and experimental immunology)
[2020, 199(2):131-142]

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Relationship between inflammation and the severity of Recurrent Respiratory Papillomatosis.

Vivian Narana Ribeiro El Achkar, Andressa Duarte, Román Carlos, Jorge Esquiche León, Alfredo Ribeiro-Silva, Shirley Shizue Nagata Pignatari, Estela Kaminagakura,

OBJECTIVE:To characterize inflammatory cells in Recurrent Respiratory Papillomatosis (RRP) and to correlate it with severity using the Derkay laryngoscopic scale. MATERIALS AND METHODS:The data and biopsies from 36 patients with Juvenile (JRRP) and 56 patients with Adult (ARRP) were collected and analyzed under light microscopy. The patients were separated into ... Read more >>

Am J Otolaryngol (American journal of otolaryngology)
[2020, 41(2):102321]

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[Perspectives on recurrent respiratory papillomatosis and human papillomavirus].

Simone Trolle, Charlotte Duch Lynggaard, Kristine Grubbe Gregersen, Louise Baandrup, Christian Grønhøj, Christian von Buchwald,

Recurrent respiratory papillomatosis (RRP) is a condition with benign tumours in the respiratory tract. RRP ensues in both children and adults. The disease is induced by low-risk human papillomavirus (HPV) types HPV-6 and HPV-11. RRP have a recurrent nature with symptoms ranging from hoarseness, dyspnoea, and dysphagia to life-threatening airway ... Read more >>

Ugeskr. Laeg. (Ugeskrift for laeger)
[2019, 181(41):]

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Efficacy of microsurgery in combined with topical-PDT in treating recurrent respiratory papillomatosis: compare JORRP with AORRP.

Shuzhi Yang, Chengyong Zhou, Baochun Sun, Feng Wang, Zeli Han, Hongjia Zhang, Jiahong Han, Yao Shen, Jiao Zhang,

Background: Recurrent respiratory papillomatosis (RRP) remains a challenging and frustrating disease to treat.Objective: To explore the efficacy of microsurgery in combined with Topical-PDT in treating recurrent respiratory papillomatosis.Materials and methods: Fifty patients with RRP were treated with microsurgery in combined with Topical-PDT. Medical document of each patient was retrospectively reviewed. ... Read more >>

Acta Otolaryngol. (Acta oto-laryngologica)
[2019, 139(12):1133-1139]

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A radiologic review of hoarse voice from anatomic and neurologic perspectives.

Simone Montoya, Anthony Portanova, Alok A Bhatt,

The differential diagnosis for hoarseness is extensive and includes a multitude of etiologies that span a large geographic area from the brainstem to the mediastinum. Therefore, localizing a causative lesion can be extremely difficult for clinicians and radiologists alike. In this review, we will first discuss the normal anatomy of ... Read more >>

Insights Imaging (Insights into imaging)
[2019, 10(1):108]

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Inverted Papilloma of the Lacrimal Sac and Nasolacrimal Duct: A Case Report and Review of the Literature.

Ya Fang Amanda Cheang, David Loke,

Inverted papillomas of the lacrimal sac and nasolacrimal duct are exceedingly rare. Though histologically benign, these tumors are locally aggressive, have propensity for recurrence and are associated with a chance of malignant transformation. These tumors can present in an innocuous manner, masquerading as more common conditions such as primary acquired nasolacrimal ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6989]

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Laryngeal Web in the Pediatric Population: Evaluation and Management.

Claire M Lawlor, Natasha D Dombrowski, Roger C Nuss, Reza Rahbar, Sukgi S Choi,

OBJECTIVE:To discuss the presentation, evaluation, and management of pediatric laryngeal web. STUDY DESIGN:Retrospective case series. SETTING:Single tertiary care center. SUBJECTS:All patients with laryngeal web at Boston Children's Hospital in the past 22 years. METHODS:No exclusion criteria. Charts mined for age at presentation, presenting symptoms, degree/location of web, associated syndromes, number/type ... Read more >>

Otolaryngol Head Neck Surg (Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery)
[2020, 162(2):234-240]

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International Pediatric Otolaryngology Group (IPOG): Juvenile-onset recurrent respiratory papillomatosis consensus recommendations.

Claire Lawlor, Karthik Balakrishnan, Sergio Bottero, An Boudewyns, Paolo Campisi, John Carter, Alan Cheng, Alejandro Cocciaglia, Alessandro DeAlarcon, Craig Derkay, Pierre Fayoux, Catherine Hart, Christopher Hartnick, Nicolas LeBoulanger, Eric Moreddu, Harlan Muntz, Richard Nicollas, Shazia Peer, Seth Pransky, Reza Rahbar, John Russell, Michael Rutter, Riaz Seedat, Douglas Sidell, Richard Smith, Marlene Soma, Julie Strychowsky, Dana Thompson, Jean-Michel Triglia, Marilena Trozzi, Michelle Wyatt, George Zalzal, Karen B Zur, Roger Nuss,

OBJECTIVES:To develop consensus recommendations for the evaluation and management of juvenile-onset recurrent respiratory papillomatosis (JORRP) in pediatric patients. METHODS:Expert opinion by the members of the International Pediatric Otolaryngology Group (IPOG). The mission of the IPOG is to develop expertise-based consensus recommendations for the management of pediatric otolaryngologic disorders with the ... Read more >>

Int. J. Pediatr. Otorhinolaryngol. (International journal of pediatric otorhinolaryngology)
[2020, 128:109697]

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The role of human papilloma virus test in men: First exhaustive review of literature.

A Vives, M Cosentino, J Palou,

Human papilloma virus (HPV) infection is the most common sexually transmitted infection worldwide. There is a high detection rate in sexually active young people but the risk, in males, persists over years. Currently, the American Center for Disease Control and Prevention does not recommend the evaluation of men for HPV ... Read more >>

Actas Urol Esp (Actas urologicas espanolas)
[2020, 44(2):86-93]

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Systemic bevacizumab for end-stage juvenile recurrent respiratory papillomas: A case report.

Osama Hamdi, Jeff Dome, George Zalzal, Diego Preciado,

We report on two cases of severe recurrent respiratory papillomatosis (RRP) involvement where the anti-vascular endothelial growth factor (VEGF) antibody bevacizumab IV has been administered for treatment. Notably, there have not been any episodes of urgent transfer to the hospital for obstructive events since the bevacizumab was started. It is ... Read more >>

Int. J. Pediatr. Otorhinolaryngol. (International journal of pediatric otorhinolaryngology)
[2020, 128:109706]

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Bilateral simultaneous sino-nasal inverted papilloma; A report of two cases and literature review.

Ali Al Momen, Haifa Lafi Alenzi, Mohammad Al Eid,

INTRODUCTION:Inverted Papilloma is a benign sinonasal tumor with a high recurrence rate and potential for malignant transformation, it typically presents as an obstructing unilateral nasal mass, atypical presentations include bilateral involvement which occurs in up to 5 % of cases. CASE PRESENTATION:Here we present two different cases of bilateral inverted ... Read more >>

Int J Surg Case Rep (International journal of surgery case reports)
[2020, 67:71-75]

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