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Towards a comprehensive understanding of p75 neurotrophin receptor functions and interactions in the brain.

Joel F Ritala, Seán B Lyne, Antti Sajanti, Romuald Girard, Janne Koskimäki,

The role of neurotrophins in neuronal plasticity has recently become a strong focus in neuroregeneration research field to elucidate the biological mechanisms by which these molecules modulate synapses, modify the response to injury, and alter the adaptation response. Intriguingly, the prior studies highlight the role of p75 neurotrophin receptor (p75<sup>NTR</sup>) ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):701-704]

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Evaluating Methylation of the Oxytocin Receptor Gene and the Oxytocin Intergenic Region.

Leonora King, Stephanie Robins, Gary Chen, Gustavo Turecki, Phyllis Zelkowitz,

Oxytocin and its paralogue, vasopressin, are widely studied biomarkers in relation to pregnancy and birth, maternal and social behavior, and mental health. Epigenetics is a biological mechanism that mediates the link between environmental influences and behavioral patterns. In a candidate gene approach, we describe here a DNA methylation assay of ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2022, 2384:81-103]

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Testing for Thyroid Peroxidase and Antineuronal Antibodies in Depression and Schizophrenia.

Johann Steiner, Winfried Stoecker, Bianca Teegen, Henrik Dobrowolny, Gabriela Meyer-Lotz, Katrin Borucki, Paul C Guest, Hans-Gert Bernstein,

Dietary interventions and physical exercise may improve some symptoms in mental illnesses such as major depression and schizophrenia. Hashimoto's thyroiditis is a known risk factor for these conditions and is marked by the presence of circulating antibodies to thyroid peroxidase (TPO) and thyroglobulin (TG). This chapter presents a protocol to ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2022, 2343:203-213]

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Forensic psychiatry services in Nunavut.

Casey Upfold, Gary Chaimowitz,

There is a paucity of research on forensic psychiatry patients from Nunavut, including no published data concerning the prevalence and characterisation of patients in this territory. The lack of basic information hinders the evaluation of services and establishing best practices. The current paper aims to characterise forensic psychiatry patients from ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1954362]

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Production of Therapeutic Single-Chain Variable Fragments (ScFv) in Pichia pastoris.

Laia Montoliu-Gaya, Sandra Villegas,

The interest in the use of monoclonal antibodies as therapeutic molecules has raised in the recent years. Due to their high affinity and specificity towards other biological molecules, antibodies are being widely used to treat a broad range of human diseases such as cancer, rheumatism, and cardiovascular diseases. Currently, the ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2022, 2313:151-167]

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Comparing the effect of xenon and sevoflurane anesthesia on postoperative neural injury biomarkers: a randomized controlled trial.

Steven McGuigan, Lisbeth Evered, David A Scott, Brendan Silbert, Henrik Zetterberg, Kaj Blennow,

General anesthesia and surgery are associated with an increase in neural injury biomarkers. Elevations of these neural injury biomarkers in the perioperative period are associated with postoperative delirium. Xenon has been shown to be protective against a range of neurological insults in animal models. It remains to be seen if ... Read more >>

Med Gas Res (Medical gas research)
[2022, 12(1):10-17]

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Curricular response to COVID-19: real-time interactive telehealth experience (RITE) program.

Joseph E Safdieh, Jennifer I Lee, Lona Prasad, Mary Mulcare, Brian Eiss, Yoon Kang,

<b>Introduction</b>. The COVID-19 pandemic placed an unprecedented strain on academic healthcare systems necessitating a pause in medical student teaching in clinical care settings, including at Weill Cornell Medicine (WCM). WCM had a preexisting telemedicine curriculum, but limited opportunities for students to apply knowledge and skills related to direct virtual patient ... Read more >>

Med Educ Online (Medical education online)
[2021, 26(1):1918609]

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Barriers and facilitators on the pathway to mental health care among 12-25 year olds.

Sophie Leijdesdorff, Rianne Klaassen, Di-Jon Wairata, Stefanie Rosema, Therese van Amelsvoort, Arne Popma,

<h4>Purpose</h4>The mismatch between the number of young people that require mental health care and who actually receive it, questions access to care. This study aims to gain in-depth understanding of barriers and facilitators in the pathway to mental health care among 12 to 25 year olds as experienced by visitors ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1963110]

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School professionals committed to student well-being.

Anna Onnela, Tuula Hurtig, Hanna Ebeling,

The northern provinces of Finland are mostly not densely populated, with long distances to healthcare services. This creates a challenge for how to reach all children and adolescents with mental health services. In order to assess the effectiveness of school-based mental health promotion interventions, it is essential to understand the ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1873589]

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The 2021-2024 Work Plan of WPA Collaborating Centres.

Andrea Fiorillo, Kamaldeep S Bhui, Dan J Stein, Tarek Okasha, David Ndetei, Linda C W Lam, Pratima Murthy, Muhammad Waqar Azeem, Afzal Javed,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2021, 20(3):457]

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Phases of psychological response in COVID-19: A preliminary heuristic.

George S Everly, Albert W Wu, James B Potash,

<h4>Objective</h4>To explore the putative phases of the psychological response to disaster: preimpact, impact, heroic, honeymoon, disillusionment, and recovery, and make recommendations for corresponding interventions.<h4>Conclusions</h4>Disasters such as the COVID-19 pandemic are often characterized by chaos and uncertainty. As a result, public health disaster planning and response represent formidable challenges. Although disasters ... Read more >>

Am J Disaster Med (American journal of disaster medicine)
[2021, 16(1):5-12]

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Post-residency medical education fellowships: a scoping review.

Mariel L Cataldi, Margot Kelly-Hedrick, Julie Nanavati, Margaret S Chisolm, Walsh Anne L,

The authors conducted a scoping review to investigate the structure, content, and potential impact of post-residency medical education fellowships. The authors searched eight databases to identify English-language articles describing longitudinal, post-residency medical fellowships that both focused on medical education and described the structure and content of the curriculum. The authors ... Read more >>

Med Educ Online (Medical education online)
[2021, 26(1):1920084]

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Correction to: Your Fear is My Fear: The Relationship Between Parental and Offspring Anxieties.

Dirk Adolph, Jürgen Margraf, Silvia Schneider,

Child Psychiatry Hum Dev (Child psychiatry and human development)
[2021, 52(5):782]

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The Lifestyle Psychiatry project of the WPA Section on Medicine, Psychiatry and Primary Care.

David Baron, Douglas Noordsy,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2021, 20(3):454-455]

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Eight-hour medication-assisted treatment waiver training for opioid use disorder: integration into medical school curriculum.

Irvin C Lien, Randell Seaton, Aaron Szpytman, Jody Chou, Victoria Webber, Eva Waineo, DianeL Levine,

<b>Background</b>: The opioid epidemic is a growing problem in the USA. Use of medication-assisted treatment (MAT) has been effective in treating patients with opioid use disorders (OUD) and maintaining sobriety; however, there is a significant shortage of physicians formally trained in MAT. <b>Objective</b>: Wayne State University School of Medicine integrated ... Read more >>

Med Educ Online (Medical education online)
[2021, 26(1):1847755]

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Correction to: Current clinical practice of electroconvulsive therapy and repetitive transcranial magnetic stimulation in psychiatry, a German sample.

Charles Timäus, Jonathan Vogelgsang, Bernhard Kis, Katrin Radenbach, Claus Wolff-Menzler, Kiriaki Mavridou, Stephan Gyßer, Philipp Hessmann, Jens Wiltfang,

Eur Arch Psychiatry Clin Neurosci (European archives of psychiatry and clinical neuroscience)
[2021, 271(7):1407]

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Psychiatric care in oncology and palliative medicine: new challenges and future perspectives.

Luigi Grassi, Michelle Riba,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2021, 20(3):452-453]

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New resources for understanding patients' values in the context of shared clinical decision-making.

Kenneth W M Fulford, Ashok Handa,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2021, 20(3):446-447]

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Advancing psychotherapy in psychiatry: the contribution of the WPA Section on Psychotherapy.

César A Alfonso, Allan Tasman, Alma L Jimenez, Constantine D Della,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2021, 20(3):453-454]

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Experiences of becoming widowed in old age - a cross-countries study with qualitative interviews from Denmark and quantitative measures of association in a Swedish sample.

Christina Blanner, Anja Elliott, Peter Hjorth, Jens Søndergaard, Cecilia Mattisson, Kjeld Andersen,

<b>Purpose</b>: Becoming widowed is a stressful health-threatening event causing major life changes. We explored how widowed people experience becoming widowed and examined if these experiences are quantitatively associated with widowhood. <b>Methods</b>: A multi-methods study using an exploratory sequential mixed-methods approach including a qualitative descriptive study with widowed people from Denmark ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1871181]

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Implementation of the WPA Action Plan 2020-2023.

Afzal Javed,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2021, 20(3):451-452]

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Three dialectics of disorder: refocusing phenomenology for 21st century psychiatry.

Guilherme Messas, Bill K W M Fulford,

Lancet Psychiatry (The lancet. Psychiatry)
[2021, 8(10):855-857]

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Failure of Losartan in a Clinical Trial for Posttraumatic Stress Disorder: Lack of Efficacy or Spotlight on the Power of Placebo?

Mary M Torregrossa,

Biol Psychiatry (Biological psychiatry)
[2021, 90(7):432-433]

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Improvement in daily functioning after aerobic exercise training in schizophrenia is sustained after exercise cessation.

Peter Falkai, Isabel Maurus, Andrea Schmitt, Berend Malchow, Thomas Schneider-Axmann, Lukas Röll, Sergi Papiol, Thomas Wobrock, Alkomiet Hasan, Daniel Keeser,

Eur Arch Psychiatry Clin Neurosci (European archives of psychiatry and clinical neuroscience)
[2021, 271(7):1201-1203]

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Conceptualizing participation in the community mental health context: Beginning with the Clubhouse model.

Kimiko Tanaka, Eric Stein, Thomas J Craig, Liv Grethe Kinn, Julie Williams,

<h4>Purpose</h4>Although participation is key to community mental health, the concept remains elusive. The study explored a conceptualization of participation in the community-based mental health agencies context from a first-person perspective, using the Clubhouse model as an example.<h4>Methods</h4>Qualitative data, collected from 21 Clubhouse service users through three focus groups (1 UK ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1950890]

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