Full Text Journal Articles about
Primary Malignant Skull Tumors

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Imaging of skull vault tumors in adults.

Albert Pons Escoda, Pablo Naval Baudin, Paloma Mora, Mònica Cos, Javier Hernandez Gañan, José A Narváez, Carles Aguilera, Carles Majós,

The skull vault, formed by the flat bones of the skull, has a limited spectrum of disease that lies between the fields of neuro- and musculoskeletal radiology. Its unique abnormalities, as well as other ubiquitous ones, present particular features in this location. Moreover, some benign entities in this region may ... Read more >>

Insights Imaging (Insights into imaging)
[2020, 11(1):23]

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T2-FLAIR mismatch sign in dysembryoplasticneuroepithelial tumor.

Shumpei Onishi, Vishwa Jeet Amatya, Manish Kolakshyapati, Motoki Takano, Ushio Yonezawa, Akira Taguchi, Yoko Kaichi, Yukio Takeshima, Kazuo Awai, Kazuhiko Sugiyama, Kaoru Kurisu, Fumiyuki Yamasaki,

PURPOSE:T2-FLAIR mismatch sign was reported as specific imaging marker in non-enhancing diffuse astrocytoma, IDH-mutant & 1p/19q non-codeleted. However, most of the previous studies for T2-FLAIR mismatch sign were confirmed only among lower grade glioma. The aim of this study is to assess the T2-FLAIR mismatch sign in dysembryoplastic neuroepithelial tumor ... Read more >>

Eur J Radiol (European journal of radiology)
[2020, 126:108924]

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Parapharyngeal schwannoma-a challenging case report.

Ângela Ferreira, Sílvia Dionísio, Eduardo Ventura, Rute Saleiro, Carlos Monteiro,

Parapharyngeal space primary neoplasias are infrequent findings in clinics, and schwannoma derived from a peripheral nerve is even rarer in this anatomic area [1]. The presented case is a patient who was referred to our department with a 3 months progressive soft palate enlargement without related symptoms. The challenge, in ... Read more >>

J Surg Case Rep (Journal of Surgical Case Reports)
[2020, 2020(3):rjaa048]

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Perivascular epithelioid cell tumor (PEComa) of the pterygopalatine fossa.

Michael I Dougherty, Spencer C Payne, Akriti Gupta, Jose L Mattos,

Perivascular epithelioid cell tumors (PEComas) are a rare group of mesenchymal tumors associated with tuberous sclerosis. These tumors are typically treated with resection and rarely recur or exhibit malignant behavior. A 78-year-old woman presented with an incidentally discovered pterygopalatine fossa/retroantral mass. Excisional biopsy was performed and revealed pathology consistent with ... Read more >>

Clin Case Rep (Clinical Case Reports)
[2020, 8(3):553-558]

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Brain Abscess as a Rare Complication of Primary Extranodal Nasal-type Natural Killer/T-cell Lymphoma.

Nobuo Ohta, Takayoshi Waki, Tsukasa Ito, Yusuke Suzuki, Seiji Kakehata, Masaru Aoyagi,

We present the case of a 58-year-old Japanese woman with a natural killer T (NK/T)-cell lymphoma complicated by brain abscess. NK/T-cell lymphomas represent a rare type of lymphoma derived from either activated NK cells or, rarely, cytotoxic T cells. They are aggressive Epstein-Barr virus (EBV)-associated lymphomas that involve mainly the ... Read more >>

Yonago Acta Med (Yonago acta medica)
[2020, 63(1):88-91]

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Chordoma with lung metastases at initial presentation of a pediatric patient.

Samiat Agunbiade, Ayman Nada, Sudhir Bhimaniya, Matthew T Whitehead, Eman S Mahdi,

Chordomas are rare, slow growing malignant tumors derived from notochord remnants that can arise anywhere along the neuronal axis. Chordomas are particularly rare in patients under 20 years of age and tend to be intracranial in location, as opposed to sacrococcygeal in adults. Metastasis at initial presentation is uncommon in ... Read more >>

Radiol Case Rep (Radiology Case Reports)
[2020, 15(4):382-386]

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[Primary skull base chondrosarcoma: a clinicopathological analysis].

Y Zhang, X N Chen, C H Ren, C Z Jiang, Y P Chen, N Lin, M Wang, S S Cai, G P Li, S Zhang, X F Wang,

Objective: To investigate the clinicopathological features, immunophenotype, molecular characteristics and differential diagnosis of primary skull base chondrosarcoma. Methods: Nine cases of primary skull base chondrosarcoma were collected at the First Affiliated Hospital of Fujian Medical University, from January 2006 to June 2019, reviewed for the clinical and radiologic data and ... Read more >>

Zhonghua Bing Li Xue Za Zhi (Zhonghua bing li xue za zhi = Chinese journal of pathology)
[2020, 49(3):239-243]

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Expanded transnasal approaches to the skull base in the Middle East: Where do we stand?

Saad Alsaleh, Abdulrahman Albakr, Saud Alromaih, Abdullah Alatar, Ahmad Salman Alroqi, Abdulrazag Ajlan,

ABSTRACTBACKGROUND: Endoscopic transnasal surgery has gained rapid global acceptance over the last two decades. The growing literature and understanding of anterior skull base endoscopic anatomy, in addition to new dedicated endoscopic instruments and tools, have helped to expand the use of the transnasal route in skull base surgery.OBJECTIVE: Report our ... Read more >>

Ann Saudi Med (Annals of Saudi medicine)
[2020, 40(2):94-104]

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Malignant perivascular epithelioid cell tumor mimicking jugular foramen schwannoma: A case report and literature review.

Noritaka Komune, Shogo Masuda, Ryuji Yasumatsu, Takahiro Hongo, Rina Jiromaru, Satoshi Matsuo, Osamu Akiyama, Nana Tsuchihashi, Nozomu Matsumoto, Hidetaka Yamamoto, Takashi Nakagawa,

Background:Perivascular epithelioid cell tumors (PEComas) of the skull base are extremely rare. Here we report the first description of a malignant PEComa mimicking jugular foramen schwannoma and presenting as Collet-Sicard syndrome, and we review the previous literature on PEComas of the head, neck and skull base. Case description:A 29-year-old woman ... Read more >>

Heliyon (Heliyon)
[2020, 6(1):e03200]

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Primary Ewing's sarcoma of the petroclival bone: A case report and literature review.

Derrek Schartz, Prashanthi Divakar, Laura Tafe, Joseph Paydarfar,

Background:Primary Ewing's sarcoma (ES) is typically seen within the long bones, vertebrae, or pelvis. Uncommonly, it can be found within the cranium among the rarest locations for primary ES are the skull base, in particular, the petroclival bone. Case Description:The patient is a 68-year-old female with past medical history of ... Read more >>

Surg Neurol Int (Surgical neurology international)
[2020, 11:6]

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Multiple Myeloma in a Young Female Presenting with Neurological Symptoms.

Matthew Lee, Xinmin Zhang, Vinh Nguyen, Monique Hartley-Brown,

Background:Multiple myeloma is overall the 14th most common malignancy but is rarely seen in those younger than 35 years. Those in the younger age group have been shown to have a more aggressive course but reportedly have had similar responses to treatment compared to older cohorts. Extramedullary plasmacytomas are discrete ... Read more >>

Case Rep Hematol (Case reports in hematology)
[2020, 2020:1375174]

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Osseous Manifestations of Primary Hyperparathyroidism: Imaging Findings.

Jackson Bennett, James W Suliburk, Fanny E Morón,

Primary hyperparathyroidism is a systemic endocrine disease that has significant effects on bone remodeling through the action of parathyroid hormone on the musculoskeletal system. These findings are important as they can aid in distinguishing primary hyperparathyroidism from other forms of metabolic bone diseases and inform physicians regarding disease severity and ... Read more >>

Int J Endocrinol (International journal of endocrinology)
[2020, 2020:3146535]

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Molecular characteristics of meningiomas.

Young Suk Lee, Youn Soo Lee,

Meningioma is the most common primary intracranial tumor in adults. The grading of meningioma is based on World Health Organization criteria, which rely on histopathological features alone. This grading system is unable to conclusively predict the clinical behavior of these tumors (i.e., recurrence or prognosis in benign or atypical grades). ... Read more >>

J Pathol Transl Med (Journal of pathology and translational medicine)
[2020, 54(1):45-63]

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Multiple Primary Malignant Neoplasms: An Unusual Case of Metachronous Breast Ductal and Squamous Cell Carcinomas.

Mohd Elmugtaba Ibrahim, Mohammed Saleh, Ahmed Ali, Navid Alavi,

Multiple primary malignant neoplasms (MPMN) are generally defined as the co-occurrence of multiple primary malignant neoplasms of distinct histology in the same individual. Second and higher-order primary malignancies now comprise about 18% of all incidence of cancer in the USA. The incidence ratio of developing multiple primary cancers (MPCs) in female cancer survivors is 1.17 to ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6954]

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Temporal bone resection for lateral skull-base malignancies.

Gautam U Mehta, Thomas J Muelleman, Derald E Brackmann, Paul W Gidley,

INTRODUCTION:Malignancies involving the temporal bone are increasingly common and require specialized multi-disciplinary care. Given this complex location, involvement of the lateral skull base and local neurovascular structures is common. In this review we discuss general principles for temporal bone resection, as well as alternative and complementary surgical approaches that should ... Read more >>

J. Neurooncol. (Journal of neuro-oncology)
[2020, :]

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Multifocal osteolytic lesions of jaw as a road map to diagnosis of brown tumor of hyperparathyroidism: A rare case report with review of literature.

Suchitra Gosavi, Harpreet Kaur, Pramod Gandhi,

Brown tumor is unifocal or multifocal bone disease which represents terminal stage of hyperparathyroidism (HPT)-dependent bone pathology. It is recognized as a component of metabolic bone disease called osteitis fibrosa cystica generalisata or Von Recklinghausen disease of bone. HPT was first described by Von Recklinghausen in 1891. Brown tumor diagnosis ... Read more >>

J Oral Maxillofac Pathol (Journal of oral and maxillofacial pathology : JOMFP)
[2020, 24(Suppl 1):S59-S66]

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Bone Metastases of Gastrointestinal Stromal Tumor: A Review of Published Literature.

Jian Yang, Jijie Yan, Meihui Zeng, Wei Wan, Tielong Liu, Jian-Ru Xiao,

Background:With the occurrence and improvement of immunohistochemistry and other pathological diagnostic techniques, gastrointestinal stromal tumor (GIST) has been gradually recognized. With the prolonged survival of patients with GISTs, reports about the bone metastasis of GIST increased. However, the knowledge of GISTs is rather limited due to its very low incidence. ... Read more >>

Cancer Manag Res (Cancer Management and Research)
[2020, 12:1411-1417]

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Birt-Hogg-Dubé syndrome with simultaneous hyperplastic polyposis of the gastrointestinal tract: case report and review of the literature.

Flávia Balsamo, Pedro Augusto Soffner Cardoso, Sergio Aparecido do Amaral Junior, Therésè Rachell Theodoro, Flavia de Sousa Gehrke, Maria Aparecida da Silva Pinhal, Bianca Bianco, Jaques Waisberg,

BACKGROUND:Birt-Hogg-Dubé syndrome (BHDS) is a rare autosomal dominant genodermatosis characterized by benign growth of the hair follicles, the presence of pulmonary cysts, spontaneous pneumothorax, and bilateral renal tumors that are usually hybrid oncocytic or multifocal chromophobe renal cell carcinoma. The diagnosis is confirmed by the presence of a pathogenic variant ... Read more >>

BMC Med. Genet. (BMC Medical Genetics)
[2020, 21(1):52]

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Best Practice in Surgical Treatment of Malignant Head and Neck Tumors.

Christian Simon, Piero Nicolai, Alberto Paderno, Andreas Dietz,

Purpose of review: Defining the best practice of surgical care for patients affected by malignant head and neck tumors is of great importance. In this review we aim to describe the evolution of "best practice" guidelines in the context of quality-of-care measures and discuss current evidence on "best practice" for ... Read more >>

Front Oncol (Frontiers in Oncology)
[2020, 10:140]

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Emerging Therapeutic Targets in Chordomas: A Review of the Literature in the Genomic Era.

Corey M Gill, Mary Fowkes, Raj K Shrivastava,

Chordomas are rare primary malignant tumors of the bones that occur along the skull base, spine, and sacrum. Long-term survival and neurological outcome continue to be challenging with continued low percentages of long-term survival. Recent studies have used genome, exome, transcriptome, and proteome sequencing to assess the mutational profile of ... Read more >>

Neurosurgery (Neurosurgery)
[2020, 86(2):E118-E123]

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Segmentation and Classification in Digital Pathology for Glioma Research: Challenges and Deep Learning Approaches.

Tahsin Kurc, Spyridon Bakas, Xuhua Ren, Aditya Bagari, Alexandre Momeni, Yue Huang, Lichi Zhang, Ashish Kumar, Marc Thibault, Qi Qi, Qian Wang, Avinash Kori, Olivier Gevaert, Yunlong Zhang, Dinggang Shen, Mahendra Khened, Xinghao Ding, Ganapathy Krishnamurthi, Jayashree Kalpathy-Cramer, James Davis, Tianhao Zhao, Rajarsi Gupta, Joel Saltz, Keyvan Farahani,

Biomedical imaging Is an important source of information in cancer research. Characterizations of cancer morphology at onset, progression, and in response to treatment provide complementary information to that gleaned from genomics and clinical data. Accurate extraction and classification of both visual and latent image features Is an increasingly complex challenge ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2020, 14:27]

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Surgical Management of Primary Skull Base Osteosarcomas: Impact of Margin Status and Patterns of Relapse.

Shaan M Raza, Ahmed Habib, Wei-Lien Wang, Paul W Gildey, Anthony P Conley, Marc-Elie Nader, Ehab Y Hanna, Shirley Y Su, Franco DeMonte,

BACKGROUND:Skull base osteosarcomas are aggressive neoplasms characterized by bony invasion and extracompartmental/extra-osseous soft tissue extension that pose obstacles to achieving complete resection. Management is further complicated by the paucity of data regarding the efficacy of surgery within the treatment paradigm. OBJECTIVE:To identify the impact of margin status on local progression ... Read more >>

Neurosurgery (Neurosurgery)
[2020, 86(1):E23-E32]

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Lymphoma Involving the Heart: A Case Report.

Randa Tabbah, Elissar Nohra, Rachoin Rachoin, Kabalan Saroufim, Bassam Harb,

Background: We describe a rare case of cardiac malignancy that counts for <1% of the primary cardiac tumors with a poor prognosis.Case summary: It's a rare case of a primary cardiac lymphoma in a 59-year-old patient who presented for recurrent pleuropericarditis with low-grade fever and night sweats. Investigations revealed an ... Read more >>

Front Cardiovasc Med (Frontiers in cardiovascular medicine)
[2020, 7:]

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Olfactory neuroblastoma pulmonary metastasis presenting as a solitary pulmonary mass in an adult: A case report with pathologic correlation.

Thangavijayan Bosemani, Dimitri G Trembath,

Pulmonary metastasis of an esthesioneuroblastoma is uncommon. In this report, we present a case of an esthesioneuroblastoma pulmonary metastasis in an adult. A 39-year-old man treated with surgical resection of olfactory neuroblastoma was found to have a solitary pulmonary mass on a surveillance computed tomography scan performed 5 years after ... Read more >>

Radiol Case Rep (Radiology case reports)
[2020, 15(4):330-333]

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[Treatment of primary craniofacial (sinonasal) malignant tumors affecting the anterior and middle skull base].

D S Spirin, I V Chernov, V A Cherekaev, P L Kalinin, V V Nazarov, I A Muzyshev, O V Absalyamova, G L Kobyakov, E R Vetlova,

Sinonasal malignant tumors are characterized by high histological variability and complexity of the differential diagnosis. Currently, there are classifications of these tumors, which are based on their localization and involvement of various anatomical structures. However, generally accepted algorithms for treatment of this pathology have not yet been developed. This review ... Read more >>

Zh Vopr Neirokhir Im N N Burdenko (Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko)
[2020, 84(1):101-108]

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