Full Text Journal Articles about
Posttransplant Lymphoproliferative Disease

Advertisement

Find full text journal articles






Epstein-Barr virus posttransplant lymphoproliferative disorder: update on management and outcomes.

Julian Lindsay, Jad Othman, Madeleine R Heldman, Monica A Slavin,

<h4>Purpose of review</h4>Management of Epstein-Barr virus posttransplant lymphoproliferative disorder (EBV PTLD) is complex, involving risk stratification, prevention and/or preemptive measures involving monitoring EBV DNAemia and balancing treatment options, using a combination of reduction of immune suppression, anti-B cell therapy, and cytotoxic T lymphocytes (CTLs).<h4>Recent findings</h4>The highest risk factor for the ... Read more >>

Curr Opin Infect Dis (Current opinion in infectious diseases)
[2021, 34(6):635-645]

Cited: 0 times

View full text PDF listing >>



Stage IV Classical Hodgkin Lymphoma-type Posttransplant Lymphoproliferative Disorder in a Pediatric Liver Transplant Patient: A Case Report and Review of the Literature.

Sujin Choi, Kyung Taek Hong, Jung Yoon Choi, Hong Yul Ahn, Jae Sung Ko, Kyung-Suk Suh, Sung-Hye Park, Jung-Eun Cheon, Hee Young Shin, Hyoung Jin Kang,

Posttransplant lymphoproliferative disorder (PTLD) is a heterogeneous group of diseases with abnormal proliferation of lymphoid tissue and classical Hodgkin lymphoma (CHL) type PTLD is a very rare subtype. We describe a successfully diagnosed and treated CHL-PTLD stage IV pediatric patient, 8 years after liver transplantation. The patient was treated with ... Read more >>

J Pediatr Hematol Oncol (Journal of pediatric hematology/oncology)
[2021, 43(7):e1015-e1019]

Cited: 0 times

View full text PDF listing >>



Advertisement

Risk constellations, viral infections, and prophylaxis in uterine transplantation.

Courtney E Harris, Nicolas C Issa,

<h4>Purpose of review</h4>Uterine transplantation (UTx) is a burgeoning new category of solid organ transplantation (SOT) that is practiced at several centers worldwide (first transplantation in 2013). Although there are still relatively low numbers of transplants (<75 published in literature), they are increasing in frequency and thus we attempt to discuss ... Read more >>

Curr Opin Organ Transplant (Current opinion in organ transplantation)
[2021, 26(6):646-653]

Cited: 0 times

View full text PDF listing >>



Unusual presentation of extranodal diffuse large B-cell lymphoma in a solid-organ recipient during long-term immunosuppressive treatment.

C Camerini, E Sant'Antonio, A Ginori, M Pellegri, C De Gaudio, E Banti, V Ciliberti, M Parrini, L Bozzoli, F Simonetti, E Capochiani,

<h4>Introduction</h4>Posttransplant lymphoproliferative disorders (PTLDs) refer to a group of diseases, including diffuse large B-cell lymphoma (DLBCL), that develop after solid organ transplantation or hematopoietic stem cell transplantation. Extranodal involvement in PTLDs is common. Reports about exclusive bone marrow involvement are rare.<h4>Case description</h4>A 70-year-old woman, who had undergone kidney transplantation in ... Read more >>

Tumori (Tumori)
[2021, :3008916211040862]

Cited: 0 times

View full text PDF listing >>



Late-Onset Posttransplant Lymphoproliferative Disorder Results in Jejunal Stricture Managed with Endoscopic Dilation.

Steven Park, John Miller, Janice Cheong, Asad Ullah, Lawrence Saubermann, Arthur Decross,

<h4>Background</h4>Late-onset posttransplant lymphoproliferative disorder (PTLD) after orthotopic heart transplantation is rare. <i>Case Presentation</i>. We present a rare diagnosis of small bowel stricture caused by healed lymphomatous ulcers in a patient with orthotopic heart transplantation and PTLD diagnosed 25 years after initial transplantation. We also demonstrate successful endoscopic balloon dilations that ... Read more >>

Case Rep Gastrointest Med (Case reports in gastrointestinal medicine)
[2021, 2021:5583665]

Cited: 0 times

View full text PDF listing >>



Kidney Transplantation and Monoclonal Gammopathy of Undetermined Significance.

Nabeel Aslam, Christopher L Trautman, Taimur Sher,

Plasma cell disorders are one of the most common hematologic malignancies. Monoclonal gammopathy of undetermined significance (MGUS) is defined by a serum monoclonal protein <3 g/dL, bone marrow plasma cell infiltration <10%, and most importantly absence of end-organ damage. The prevalence of MGUS in general population is estimated to be 1%-4% ... Read more >>

Transplant Direct (Transplantation direct)
[2021, 7(8):e723]

Cited: 0 times

View full text PDF listing >>



Long-term Follow-up of a Randomized Trial of Tacrolimus or Cyclosporine A Microemulsion in Children Post Liver Transplantation.

Carla Lloyd, Adam Arshad, Paloma Jara, Martin Burdelski, Bruno Gridelli, J Manzanares, Michele Colledan, Emmanuel Jacquemin, Raymond Reding, Ulrich Baumann, Deirdre Kelly,

The aim of this study was to determine the long-term efficacy and safety of tacrolimus (Tac) and cyclosporine immunosuppression in pediatric liver transplantation (LTx).<h4>Methods</h4>One hundred fifty-six patients who had taken part in a multicenter, randomized, open, parallel study of Tac and corticosteroids versus cyclosporine A microemulsion (CyA-ME), corticosteroids, and azathioprine. ... Read more >>

Transplant Direct (Transplantation direct)
[2021, 7(10):e765]

Cited: 0 times

View full text PDF listing >>



Distinct immunopathological mechanisms of EBV-positive and EBV-negative posttransplant lymphoproliferative disorders.

Cecilia Nakid-Cordero, Sylvain Choquet, Nicolas Gauthier, Noureddine Balegroune, Nadine Tarantino, Véronique Morel, Nadia Arzouk, Sonia Burrel, Géraldine Rousseau, Frédéric Charlotte, Martin Larsen, Vincent Vieillard, Brigitte Autran, Véronique Leblond, Amélie Guihot, ,

EBV-positive and EBV-negative posttransplant lymphoproliferative disorders (PTLDs) arise in different immunovirological contexts and might have distinct pathophysiologies. To examine this hypothesis, we conducted a multicentric prospective study with 56 EBV-positive and 39 EBV-negative PTLD patients of the K-VIROGREF cohort, recruited at PTLD diagnosis and before treatment (2013-2019), and compared them to PTLD-free ... Read more >>

Am J Transplant (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
[2021, 21(8):2846-2863]

Cited: 2 times

View full text PDF listing >>



Live Vaccines in Pediatric Liver Transplant Recipients: “To Give or Not to Give”

Sarah Kemme, Taisa J. Kohut, Julia M. Boster, Tamir Diamond, Elizabeth B. Rand, Amy G. Feldman,

Content available: Author Audio Recording ... Read more >>

Clin Liver Dis (Hoboken) (Clinical liver disease)
[2021, 18(4):204-210]

Cited: 0 times

View full text PDF listing >>



Heterogeneous Manifestations of Posttransplant Lymphoma in Renal Transplant Recipients: A Case Series.

Rujuta Patil, Rohini Prashar, Anita Patel,

Posttransplant lymphoproliferative disorder (PTLD) occurs in 1% to 3% of adult renal transplant recipients (RTRs). PTLD has a heterogeneous presentation and is often associated with Epstein-Barr virus (EBV) and immunosuppression. We present a descriptive case series of 16 RTRs who demonstrate a variety of PTLD manifestations. Fifty-six percent received rabbit ... Read more >>

Transplant Proc (Transplantation proceedings)
[2021, 53(5):1519-1527]

Cited: 0 times

View full text PDF listing >>



Treosulfan-Based Conditioning Regimen Prior to Allogeneic Stem Cell Transplantation: Long-Term Results From a Phase 2 Clinical Trial.

Lorenzo Lazzari, Annalisa Ruggeri, Maria Teresa Lupo Stanghellini, Sara Mastaglio, Carlo Messina, Fabio Giglio, Alessandro Lorusso, Tommaso Perini, Simona Piemontese, Magda Marcatti, Francesca Lorentino, Elisabetta Xue, Daniela Clerici, Consuelo Corti, Massimo Bernardi, Andrea Assanelli, Raffaella Greco, Fabio Ciceri, Jacopo Peccatori,

<h4>Introduction</h4>Reducing toxicities while preserving efficacy in allogeneic stem cell transplant (allo-HCT) remains a particularly challenging problem. Different strategies to enhance the antitumor activity without increasing early and late adverse toxicities of the conditioning regimens have been investigated.<h4>Methods</h4>The aim of "AlloTreo" prospective phase 2 clinical trial was to evaluate the efficacy ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:731478]

Cited: 0 times

View full text PDF listing >>



Risk Factors for the Incidence of Post-Transplantation Lymphoproliferative Disorder and Mortality due to Post-Transplantation Lymphoproliferative Disorder after Hematopoietic Cell Transplantation.

Megan Kinzel, Michelle Dowhan, Amit Kalra, Tyler S Williamson, Rosy Dabas, Kareem Jamani, Ahsan Chaudhry, Mona Shafey, Victor Jimenez-Zepeda, Peter Duggan, Andrew Daly, Poonam Dharmani-Khan, Faisal Khan, Jan Storek,

Post-transplantation lymphoproliferative disorder (PTLD) is a potentially serious complication that occurs following hematopoietic cell transplantation (HCT), in which B cells transformed by Epstein-Barr virus (EBV) proliferate uncontrollably. It is unknown whether risk factors for the incidence of PTLD are identical to those for mortality due to PTLD, a clinically more ... Read more >>

Transplant Cell Ther (Transplantation and cellular therapy)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Primary Central Nervous System Posttransplant Lymphoproliferative Disorder After Kidney Transplant.

Trevor Stone, Ramin Eskandari, Tiffany Baker, Michael Antonucci, Milad Yazdani,

Primary central nervous system posttransplant lymphoproliferative disorder is a rare complication of solid organ transplantation, with increasing incidence in children given a steady rise in pediatric solid organ transplants. Given similar imaging appearance to many opportunistic infections, a high degree of awareness is required for prompt and early diagnosis. We ... Read more >>

J Pediatr Hematol Oncol (Journal of pediatric hematology/oncology)
[2021, 43(4):144-146]

Cited: 0 times

View full text PDF listing >>



Characteristics of T- and NK-cell Lymphomas After Renal Transplantation: A French National Multicentric Cohort Study.

Thomas Barba, Emmanuel Bachy, Alizée Maarek, Gaëlle Fossard, Laurent Genestier, Dany Anglicheau, Valérie Moal, Jacques Dantal, Philippe Rieu, Jonathan Chemouny, Manon Charrier, Antoine Durrbach, François Provot, Didier Ducloux, Pierre-François Westeel, Anne-Elisabeth Heng, Jean-Philippe Rerolle, Benoit Barrou, Philippe Grimbert, Valérie Chatelet, Christiane Mousson, Bénédicte Janbon, Vincent Pernin, Luc Frimat, Nacera Ouali, Denis Glotz, Antoine Thierry, Christophe Mariat, Mathias Büchler, Philippe Gaulard, Véronique Leblond, Emmanuel Morelon, Valérie Dubois, Gilles Salles, Sophie Caillard, Olivier Thaunat,

<h4>Background</h4>Posttransplant lymphoproliferative disorders (PTLDs) encompass a spectrum of heterogeneous entities. Because the vast majority of cases PTLD arise from B cells, available data on PTLD of T or NK phenotype (T/NK-cell PTLD) are scarce, which limits the quality of the management of these patients.<h4>Methods</h4>All adult cases of PTLD diagnosed in ... Read more >>

Transplantation (Transplantation)
[2021, 105(8):1858-1868]

Cited: 0 times

View full text PDF listing >>



Autoimmunity in Wiskott-Aldrich Syndrome: Updated Perspectives.

Murugan Sudhakar, Rashmi Rikhi, Sathish Kumar Loganathan, Deepti Suri, Surjit Singh,

Wiskott-Aldrich syndrome (WAS) is an uncommon X-linked combined-immunodeficiency disorder characterized by a triad of thrombocytopenia, eczema, and immunodeficiency. Patients with WAS are also predisposed to autoimmunity and malignancy. Autoimmune manifestations have been reported in 26%-72% of patients with WAS. Autoimmunity is an independent predictor of poor prognosis and predisposes to ... Read more >>

Appl Clin Genet (The application of clinical genetics)
[2021, 14:363-388]

Cited: 0 times

View full text PDF listing >>



Posttransplant Lymphoproliferative Disorder After Solid Organ Transplant: A Heterogeneous, Aggressive Disorder.

Laura McDonald, Roseann O' Doherty, Eileen Ryan, Helen Enright, Eoghan Dunlea, Sarah Kelliher, Anne Fortune, Michael Fay, S W Maung, Ronan Desmond, Catherine Wall, Senthil Kumar, Derville O' Shea, Kamal Fadalla, D G Connaghan, Liam Smyth,

Posttransplant lymphoproliferative disorder (PTLD) is a rare complication of solid organ transplant. We identified 40 patients diagnosed with PTLD between 2009 and 2020 and analyzed their presentation, treatment strategies, and outcomes. Median age at diagnosis was 52.5 years (range 21.3 to 79). Median duration of immunosuppression was 95 months (range ... Read more >>

Clin Lymphoma Myeloma Leuk (Clinical lymphoma, myeloma & leukemia)
[2021, 21(10):694-700]

Cited: 0 times

View full text PDF listing >>



Acute Kidney Injury Following Chimeric Antigen Receptor T-Cell Therapy for B-Cell Lymphoma in a Kidney Transplant Recipient.

Edoardo Melilli, Alberto Mussetti, Gabriela Sanz Linares, Marco Ruella, Charette La Salette, Alexandre Savchenko, Maria Del Rosario Taco, Nuria Montero, Josep Grinyo, Alex Fava, Montse Gomà, Maria Meneghini, Anna Manonelles, Josepmaria Cruzado, Ana Sureda, Oriol Bestard,

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy is a newer and effective therapeutic option approved for patients with relapsed/refractory acute lymphoblastic leukemia and diffuse large B-cell lymphoma. Acute kidney injury is a complication of CAR T-cell therapy that can result in kidney failure. In most cases, it is thought to ... Read more >>

Kidney Med (Kidney medicine)
[2021, 3(4):665-668]

Cited: 0 times

View full text PDF listing >>



Multifactorial Hyponatremia in a Lung Transplant Recipient: A Case Report of Pseudohyponatremia, SIADH and Secondary Adrenal Insufficiency

Rani Shayto,

Abstract Background: Lung transplant recipients are prone to developing multifactorial hyponatremia from immunosuppressive therapies and posttransplant lymphoproliferative disorders. Clinical Case: A 77-year-old male with a history of lung transplantation in 2017 presented for a 3-month history of confusion, decline in executive function and chronic abdominal pain. Vital signs were BP ... Read more >>

J Endocr Soc (Journal of the Endocrine Society)
[2021, 5(Suppl 1):A143-A144]

Cited: 0 times

View full text PDF listing >>



A 9-year-old male with Barth syndrome and cardiac transplant presenting with hyperviscosity syndrome caused by EBV-negative plasmacytoid posttransplant lymphoproliferative disorder.

Yixian Li, Rachel Offenbacher, Nicolas H Corral, Neha Bansal, Juan Ding, Lisa Gennarini, Leanne Ostrodka, Adit Tal,

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68(12):e29264]

Cited: 0 times

View full text PDF listing >>



Safety and Efficacy of Anti-CD19-Chimeric Antigen Receptor T Cell Combined With Programmed Cell Death 1 Inhibitor Therapy in a Patient With Refractory Post-Transplant Lymphoproliferative Disease: Case Report and Literature Review.

Gang Feng, Qing Li, Haibo Zhu, Yanyu Jiang, Jijun Yuan, Yingxin Fu, Qi Deng,

Post-transplant lymphoproliferative disease (PTLD) often exhibits poor prognosis and high mortality, and there are no uniform guidelines for the treatment of this disease. Anti-CD19 chimeric antigen receptor (CAR) T cells show significant efficacy in treatment of relapse/refractory diffuse large B-cell lymphoma (DLBCL). Treatment using anti-CD19-CAR T-cell therapy in PTLD has ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:726134]

Cited: 0 times

View full text PDF listing >>



An Unusual Cause of Acute Pancreatitis in a Liver Transplant Recipient.

Imran Nizamuddin, Themistoklis Kourkoumpetis, Cecil G Wood, Josh Levitsky,

Posttransplant lymphoproliferative disorder (PTLD) in liver transplant recipients is relatively uncommon, with an estimated incidence of 1%-3%. Retrospective reviews of liver transplant recipients have mainly reported posttransplant lymphoproliferative disorder affecting the liver, gastrointestinal tract, or lymph nodes. In this case report, we describe a 45-y-old female with a history of ... Read more >>

Transplant Direct (Transplantation direct)
[2021, 7(5):e694]

Cited: 0 times

View full text PDF listing >>



Treatment of posttransplant lymphoproliferative disorder with poor prognostic features in children and young adults: Short-course EPOCH regimens are safe and effective.

Jeremy D Rubinstein, Rachana Shah, Erin H Breese, Karen C Burns, Jennifer L Mangino, Robin E Norris, Lynn Lee, Benjamin Mizukawa, Maureen M O'Brien, Christine L Phillips, John P Perentesis, Lauren Pommert, Michael J Absalon,

No guidelines exist for which intensive chemotherapy regimen is best in pediatric or young adult patients with high-risk posttransplant lymphoproliferative disorder (PTLD). We retrospectively reviewed patients with PTLD who received interval-compressed short-course etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin (SC-EPOCH) regimens at our institution. Eight patients were included with median age of ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68(8):e29126]

Cited: 0 times

View full text PDF listing >>



Posttransplant Lymphoproliferative Disorder Following Kidney Transplantation: A Review.

Ben Sprangers, Leonardo V Riella, Daan Dierickx,

Posttransplant lymphoproliferative disorder (PTLD) is one of the most feared complications following kidney transplantation. Over a 10-year period, the risk of PTLD in kidney transplant recipients (KTRs) is 12-fold higher than in a matched nontransplanted population. Given the number of kidney transplants performed, KTRs who experience PTLD outnumber other organ ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2021, 78(2):272-281]

Cited: 1 time

View full text PDF listing >>



Zanubrutinib Treatment of Central Nervous System Posttransplant Lymphoproliferative Disorder After Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report.

Ting-Ting Yang, Wei-Hao Chen, Yan-Min Zhao, Hua-Rui Fu, He Huang, Ji-Min Shi,

Posttransplant lymphoproliferative disorder (PTLD) is a rare complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT) with poor prognosis. We report a patient with PTLD involved central nervous system (CNS) who treated with zanubrutinib, a second-generation Bruton tyrosine kinase (BTK) inhibitor. Our report supports the efficacy of bruton tyrosine kinase inhibitor zanubrutinib ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:672052]

Cited: 0 times

View full text PDF listing >>



The diagnostic challenge of adenocarcinoma in pulmonary nodular lymphoid hyperplasia.

Anita Savić Vuković, Melita Kukuljan, Morana Dinter, Ksenija Jurinović, Nives Jonjić,

Pulmonary nodular lymphoid hyperplasia is a rare, nonneoplastic lymphoproliferative disorder mostly manifesting as one or more nodules or localized lung infiltrates. The lesion comprises reactive germinal centers with well-preserved mantle zones and sheets of interfollicular mature plasma cells, lymphocytes, histiocytes, and neutrophils. The radiological finding is not specific, and the ... Read more >>

SAGE Open Med Case Rep (SAGE open medical case reports)
[2021, 9:2050313X211039371]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.1422 s