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Postherpetic Neuralgia

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Efficacy and safety of the extracorporeal shock wave therapy in patients with postherpetic neuralgia: study protocol of a randomized controlled trial

Ling Ye, Lu Chen, Ruihao Zhou, Fuguo Sun, Yan Weng, Pingliang Yang,

<title>Abstract</title> <p> Background: Postherpetic neuralgia (PHN) is one of the most common chronic neuropathic pain, which seriously affected the quality of the life due to the severity of pain and the poor response to the current treatment. The main management strategies of PHN include medication therapy and invasive ... Read more >>

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Comparison of therapeutic effects of continuous epidural nerve block combined with drugs on postherpetic neuralgia.

Xi'an Dong, Yuantao Liu, Qianqian Yang, Zhaobin Liu, Zipu Zhang,

Purpose: To compare the therapeutic effects of continuous epidural block combined with drugs and oral drugs alone on postherpetic neuralgia (PHN).Methods: Ninety-six PHN patients meeting the standard were selected and divided into group A and group B. Patients in group A had epidural block combined with oral administration of gabapentin ... Read more >>

Int. J. Neurosci. (The International journal of neuroscience)
[2020, :1-5]

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Therapeutic Effects of Continuous Epidural Infusion of Local Anesthetics with Dexamethasone for Postherpetic Neuralgia

Eun Mi Choi, Mi Hwa Chung, Joo-Hyun Jun, Eun Hee Chun, In-Jung Jun, Jong Hee Park, Eun-Ha Choi, Jung Eun Kim,

The most common complication of herpes zoster is postherpetic neuralgia (PHN), which is accompanied by severe pain that lowers patients&rsquo; quality of life. Although epidural injection of local anesthetics and steroids is effective in controlling neuropathic pain resulting from herpes zoster, few studies report the efficacy and safety of epidural ... Read more >>

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Early Treatment with Temporary Spinal Cord Stimulation Effectively Prevents Development of Postherpetic Neuralgia.

Jiabin Huang, Shaomin Yang, Juan Yang, Wuping Sun, Changyu Jiang, Jiehua Zhou, Disen Li, Donglin Xiong, Dan Bates, Lizu Xiao,

BACKGROUND:Some 7.7% of the Chinese population suffer from herpes zoster each year, with 29.8% proceeding on to develop postherpetic neuralgia (PHN). This amounts to over 32 million people per year. PHN is preceded by 2 phases of pain: acute herpetic neuralgia (AHN), and subacute herpetic neuralgia (SHN). Considering the large ... Read more >>

Pain Physician (Pain physician)
[2020, 23(2):E219-E230]

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Efficacy of extracorporeal shockwave therapy in the treatment of postherpetic neuralgia: A pilot study.

Sung Hyun Lee, Kyoung-Ho Ryu, Pyoung On Kim, Hyo-Won Lee, Eun-Ah Cho, Jin-Hee Ahn, Inyoung Youn, Kyung Seung Yang,

Established conventional treatments for postherpetic neuralgia (PHN) and postherpetic itch (PHI) are difficult and often disappointing. In this study, the authors investigated the effect and mechanisms of extracorporeal shockwave therapy (ESWT) on pain and itch associated with PHN and PHI.Thirteen patients, 50 to 80 years of age, with symptoms associated ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(12):e19516]

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Herpes zoster vaccination in Australia: what's available and who benefits?

Sanjay Jayasinghe, Sarah Sheridan, Kristine Macartney,

Acute herpes zoster and associated postherpetic neuralgia is caused by reactivation of latent varicella zoster virus It can be debilitating for older adults and interfere with activities of daily living: A live attenuated single-dose vaccine that protects against both acute herpes zoster and postherpetic neuralgia is available for free to ... Read more >>

Aust Prescr (Australian prescriber)
[2020, 43(1):2-6]

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A combined DTI and resting state functional MRI study in patients with postherpetic neuralgia.

Hui Dai, Chengcheng Jiang, Guanzuan Wu, Renjun Huang, Xiaohong Jin, Zhongshuai Zhang, Lina Wang, Yonggang Li,

PURPOSE:To explore the brain microstructural and functional changes in patients with postherpetic neuralgia (PHN). MATERIALS AND METHODS:12 PHN patients and 12 healthy volunteers were enrolled. Diffusion tensor imaging (DTI) and resting-state functional MRI (rfMRI) sequences were scanned by a 3T MR scanner. Fractional anisotropy (FA) and mean diffusivity (MD) t-maps ... Read more >>

Jpn J Radiol (Japanese journal of radiology)
[2020, :]

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Lumbar Erector Spine Plane Block for Pain Management in Postherpetic Neuralgia in a Patient with Chronic Lymphocytic Leukemia.

Abhishek Kumar, Tuhin Mistry, Nishkarsh Gupta, Vinod Kumar, Sushma Bhatnagar,

Postherpetic neuralgia (PHN) refers to the chronic neuropathic pain that persists beyond the initial varicella-zoster rash. Patients with chronic lymphocytic leukemia (CLL) are susceptible to infections because of decreased immunity. Various treatment strategies including pharmacological, nonpharmacological, and interventional techniques have been described in the literature. We report the successful management ... Read more >>

Indian J Palliat Care (Indian journal of palliative care)
[2020, 26(1):134-136]

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Effectiveness of electroacupuncture at Jiaji acupoints (EX-B2), plus moxibustion and intermediate on postherpetic neuralgia: a randomized controlled trial.

Lei Wang, Ling Qiu, Xu Zheng, Jianbing Ouyang, Min Zhang, Liu He, Shuai Zeng, Bo Liu, Jinlin Peng,

OBJECTIVE:To investigate the effectiveness of electroacupuncture at Jiaji acupoints (EX-B 2) plus moxibustion and intermediate frequency on postherpetic neuralgia (PHN). METHODS:A total of 140 outpatients who satisfied the inclusion criteria and volunteered for this treatment were randomly divided into treatment (n = 70) and control (n = 70) groups. Both ... Read more >>

J Tradit Chin Med (Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan)
[2020, 40(1):121-127]

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Pregabalin for postherpetic itch: a case report.

Nobuhiro Shimada, Yasunori Niwa, Kunihisa Hotta, Takashi Igarashi, Mamoru Takeuchi,

BACKGROUND:Postherpetic itch has not commonly received attention as a complication of herpes zoster because pain predominates over itch in most patients with herpes zoster. Most cases of postherpetic itch are mild; however, cases of severe postherpetic itch reducing quality of life are rare. CASE PRESENTATION:A 52-year-old woman complained of severe ... Read more >>

JA Clin Rep (JA clinical reports)
[2020, 6(1):24]

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Impaired hemodynamic activity in the right dorsolateral prefrontal cortex is associated with impairment of placebo analgesia and clinical symptoms in postherpetic neuralgia.

Daisuke Hibi, Kouichi Takamoto, Yudai Iwama, Shohei Ebina, Hiroshi Nishimaru, Jumpei Matsumoto, Yusaku Takamura, Mitsuaki Yamazaki, Hisao Nishijo,

The dorsolateral prefrontal cortex (dlPFC) is functionally linked to the descending pain modulation system and has been implicated in top down pain inhibition, including placebo analgesia. Therefore, functions of the dlPFC may be impaired in patients with chronic pain. Postherpetic neuralgia (PHN) is one of several syndromes with chronic neuropathic ... Read more >>

IBRO Rep (IBRO reports)
[2020, 8:56-64]

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An Unusual Presentation of Herpes Zoster.

Robert C Tung, Adnan Shaaban, Mira Kim, Peter Cristiano,

Kans J Med (Kansas journal of medicine)
[2020, 13:19-20]

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Mirogabalin besylate in the treatment of neuropathic pain.

J Burgess, S Javed, B Frank, R A Malik, U Alam,

Neuropathic pain (NeP) is a global cause of suffering and debilitation leading to significant morbidity and reduced quality of life. New treatments are needed to address the growing prevalence of NeP and its impact on sleep, mood and functionality. Mirogabalin besylate (mirogabalin, Tarlige) is a gabapentinoid therapy developed by Daiichi ... Read more >>

Drugs Today (Drugs of today (Barcelona, Spain : 1998))
[2020, 56(2):135-149]

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Efficacy of continuous epidural infusion with epidural electric stimulation compared to that of conventional continuous epidural infusion for acute herpes zoster management: A retrospective study

Sang Sik Choi, Chung Hun Lee, Mi Kyoung Lee, Yeon Joo Lee, Jong Sun Park,

<title>Abstract</title> <p> <bold>Background: </bold>Continuous epidural infusions are commonly used in clinical settings to reduce the likelihood of transition to postherpetic neuralgia via pain control.<bold> </bold>The purpose of this study was to compare the efficacy of conventional continuous epidural infusion to that of continuous epidural infusion in which the ... Read more >>

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Delayed Initiation of Supplemental Pain Management is Associated with Postherpetic Neuralgia: A Retrospective Study.

Xiufang Xing, Kai Sun, Min Yan,

BACKGROUND:Acute pain is a risk factor for developing postherpetic neuralgia (PHN), the most common complication of herpes zoster (HZ). Supplemental analgesics are frequently used in the treatment of acute herpetic pain. However, there are insufficient data regarding when to begin supplemental analgesics, and it is unknown whether the delayed use ... Read more >>

Pain Physician (Pain physician)
[2020, 23(1):65-72]

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S2k guidelines for the diagnosis and treatment of herpes zoster and postherpetic neuralgia.

Gerd E Gross, Lisa Eisert, Hans Wilhelm Doerr, Helmut Fickenscher, Markus Knuf, Philip Maier, Matthias Maschke, Rainer Müller, Uwe Pleyer, Michael Schäfer, Cord Sunderkötter, Ricardo N Werner, Peter Wutzler, Alexander Nast,

The present guidelines are aimed at residents and board-certified specialists in the fields of dermatology, ophthalmology, ENT, pediatrics, neurology, virology, infectious diseases, anesthesiology, general medicine and any other medical specialties involved in the management of patients with herpes zoster. They are also intended as a guide for policymakers and health ... Read more >>

J Dtsch Dermatol Ges (Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG)
[2020, 18(1):55-78]

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Test-Retest and Inter-Examiner Reliability of a Novel Bedside Quantitative Sensory Testing Battery in Postherpetic Neuralgia Patients.

Ajay D Wasan, Benedict J Alter, Robert R Edwards, Charles E Argoff, Nalini Sehgal, David Walk, Toby Moeller-Bertram, Mark S Wallace, Misha Backonja,

In health and disease, the somatosensory system has been interrogated with standardized research techniques, collectively referred to as quantitative sensory testing (QST). In neuropathic pain, QST has been used to characterize multiple sensory derangements. However, the use of QST outside the lab has been limited by several factors, including a ... Read more >>

J Pain (The journal of pain : official journal of the American Pain Society)
[2019, :]

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[Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape].

Max J Hassenstein, Ghazal Aarabi, Peter Ahnert, Heiko Becher, Claus-Werner Franzke, Julia Fricke, Gérard Krause, Stephan Glöckner, Cornelia Gottschick, André Karch, Yvonne Kemmling, Tobias Kerrinnes, Berit Lange, Rafael Mikolajczyk, Alexandra Nieters, Jördis J Ott, Wolfgang Ahrens, Klaus Berger, Claudia Meinke-Franze, Sylvia Gastell, Kathrin Günther, Karin Halina Greiser, Bernd Holleczek, Johannes Horn, Lina Jaeschke, Annika Jagodzinski, Lina Jansen, Carmen Jochem, Karl-Heinz Jöckel, Rudolf Kaaks, Lilian Krist, Oliver Kuß, Susan Langer, Nicole Legath, Michael Leitzmann, Wolfgang Lieb, Markus Loeffler, Nina Mangold, Karin B Michels, Christa Meisinger, Nadia Obi, Tobias Pischon, Tamara Schikowski, Sabine Schipf, Matthias B Schulze, Andreas Stang, Sabina Waniek, Kerstin Wirkner, Stefan N Willich, Stefanie Castell,

BACKGROUND:Infectious diseases continue to play an important role for disease perception, health-economic considerations and public health in Germany. In recent years, infectious diseases have been linked to the development of non-communicable diseases. Analyses of the German National Cohort (GNC) may provide deeper insights into this issue and pave the way ... Read more >>

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz (Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
[2020, 63(4):404-414]

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Modulation of Voltage-Gated Sodium Channel Activity in Human Dorsal Root Ganglion Neurons by Herpesvirus Quiescent Infection.

Qiaojuan Zhang, Miguel Martin-Caraballo, S Victor Hsia,

The molecular mechanisms of pain associated with alphaherpesvirus latency are not clear. We hypothesize that the voltage-gated sodium channels (VGSC) on the dorsal root ganglion (DRG) neurons controlling electrical impulses may have abnormal activity during latent viral infection and reactivation. We used herpes simplex virus 1 (HSV-1) to infect the ... Read more >>

J. Virol. (Journal of Virology)
[2020, 94(3):]

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Efficacy of continuous epidural infusion with epidural electric stimulation compared to that of conventional continuous epidural infusion for acute herpes zoster management: a retrospective study.

Chung Hun Lee, Sang Sik Choi, Mi Kyoung Lee, Yeon Joo Lee, Jong Sun Park,

BACKGROUND:Continuous epidural infusions are commonly used in clinical settings to reduce the likelihood of transition to postherpetic neuralgia via pain control. The purpose of this study was to compare the efficacy of conventional continuous epidural infusion to that of continuous epidural infusion in which the catheter is guided by electric ... Read more >>

BMC Anesthesiol (BMC anesthesiology)
[2020, 20(1):26]

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Subcutaneous botulinum toxin-A injection for treating postherpetic neuralgia.

Yanqing Hu, Liping Zou, Xinyu Qi, Yan Lu, Xianyi Zhou, Zuhao Mao, Xuyang Chen, Kangxing Liu, Yemei Yang, Zhong Wu, Yongxuan Hu, Shanling Ma,

Postherpetic neuralgia (PHN) is a debilitating disease characterized by continuous, intense pain following an outbreak of herpes zoster. The pain associated with PHN can severely affect a patient's quality of life, quality of sleep, and ability to participate in activities of daily living. The aim of this study was to ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2020, 33(1):e13181]

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Aggregate health and economic burden of herpes zoster in the United States: illustrative example of a pain condition.

Michael Harvey, Lisa A Prosser, Angela M Rose, Ismael R Ortega-Sanchez, Rafael Harpaz,

Our objective was to develop comprehensive national estimates of the total burden of herpes zoster (HZ) among U.S. adults, including direct (ie, medical costs) and indirect (ie, productivity losses) costs, as well as its psychosocial impact (ie, quality of life losses). Using a patient-level microsimulation model, we projected health and ... Read more >>

Pain (Pain)
[2020, 161(2):361-368]

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Risk of herpes zoster in the Japanese population with immunocompromising and chronic disease conditions: Results from a claims database cohort study, from 2005 to 2014.

Shinichi Imafuku, Giulia Dormal, Yasushi Goto, Céline Jégou, Dominique Rosillon, Taizo Matsuki,

Older adults, women and patients with immunocompromised (IC) or chronic medical conditions have a higher incidence of herpes zoster (HZ) and are at higher risk of developing HZ-associated complications such as postherpetic neuralgia. The incidence rates of HZ in various IC and chronic conditions have been previously reported in a ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, 47(3):236-244]

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Association between neuropathic pain characteristics and DNA methylation of transient receptor potential ankyrin 1 in human peripheral blood.

Shiho Takenaka, Norihiko Sukenaga, Masaki Ohmuraya, Yuka Matsuki, Lynn Maeda, Yumiko Takao, Munetaka Hirose,

Elucidation of epigenetic mechanisms correlating with neuropathic pain in humans is crucial for the prevention and treatment of this treatment-resistant pain state. In the present study, associations between neuropathic pain characteristics and DNA methylation of the transient receptor potential ankyrin 1 (TRPA1) gene were evaluated in chronic pain patients and ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(8):e19325]

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Case Report Of Cryoneurolysis For The Treatment Of Refractory Intercostobrachial Neuralgia With Postherpetic Neuralgia.

Garret Weber, Kenneth Saad, Motaz Awad, Tiffany H Wong,

Postherpetic neuralgia is a common and potentially debilitating neuropathic pain condition. Current pharmacologic therapy can be inadequate and intolerable for patients. We present a case of a gentleman with refractory postherpetic neuralgia in the intercostobrachial nerve distribution that was successfully treated with cryoneurolysis/cryoanalgesia therapy. ... Read more >>

Local Reg Anesth (Local and regional anesthesia)
[2019, 12:103-107]

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