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Pediatric Sinus of Valsalva Aneurysm

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Streptococcus pyogenes Endocarditis Associated With Varicella-Case Report and Review of the Literature.

Patrizia Savoia, Ulrich Heininger, Michael Buettcher,

Infection with varicella zoster virus (VZV) is usually a benign and self-limiting disease. Serious complications by bacterial pathogens do occur, such as necrotising fasciitis (NF). One of the most important is Streptococcus pyogenes (or Group A Streptococcus, GAS), which colonizes epithelial surfaces, primarily of the throat and skin. In rare ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:500]

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Ruptured Sinus of Valsalva Aneurysm Mimicking Infective Endocarditis in DiGeorge Syndrome.

Salima A Bhimani, Geetha Challapudi, Hani K Najm, Rukmini Komarlu,

Sinus of Valsalva aneurysm (SOVA) is rare and can occur in diseases with progressive aortic dilation. We report an adolescent male with DiGeorge syndrome who presented with fever and wide pulse pressure mimicking endocarditis. A timely diagnosis of ruptured SOVA using echocardiography enabled optimal treatment. Our case highlights the need ... Read more >>

J Cardiovasc Echogr (Journal of cardiovascular echography)
[2019, 29(4):177-179]

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Differences in Aortopathy in Patients with a Bicuspid Aortic Valve with or without Aortic Coarctation.

Anthonie Duijnhouwer, Allard van den Hoven, Remy Merkx, Michiel Schokking, Roland van Kimmenade, Marlies Kempers, Arie van Dijk, Menko-Jan de Boer, Jolien Roos-Hesselink,

OBJECTIVE:The combination of aortic coarctation (CoA) and bicuspid aortic valve (BAV) is assumed to be associated with a higher risk of ascending aortic dilatation and type A dissection, and current European Society of Cardiology (ESC) guidelines advise therefore to operate at a lower threshold in the presence of CoA. The ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(2):]

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Case-matched Comparison of Cardiovascular Outcome in Loeys-Dietz Syndrome versus Marfan Syndrome.

Kristina Mühlstädt, Julie De Backer, Yskert von Kodolitsch, Kerstin Kutsche, Laura Muiño Mosquera, Jens Brickwedel, Evaldas Girdauskas, Thomas S Mir, Adrian Mahlmann, Nikolaos Tsilimparis, Axel Staebler, Lauritz Schoof, Heide Seidel, Jürgen Berger, Alexander M Bernhardt, Stefan Blankenberg, Tilo Kölbel, Christian Detter, Katalin Szöcs, Harald Kaemmerer,

Background: Pathogenic variants in TGFBR1, TGFBR2 and SMAD3 genes cause Loeys-Dietz syndrome, and pathogenic variants in FBN1 cause Marfan syndrome. Despite their similar phenotypes, both syndromes may have different cardiovascular outcomes. Methods: Three expert centers performed a case-matched comparison of cardiovascular outcomes. The Loeys-Dietz group comprised 43 men and 40 ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 8(12):]

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-10-French)-Venous-Hemostasis.">Efficacy and Safety of Subcutaneous Fellow's Stitch Using "Fisherman's Knot" Technique to Achieve Large Caliber (> 10 French) Venous Hemostasis.

Prakash Kumar, Puneet Aggarwaal, Santosh Kumar Sinha, Umeshwar Pandey, Mahmodula Razi, Awdesh Kumar Sharma, Ramesh Thakur, Chandra Mohan Varma, Vinay Krishna,

Background:Among patients undergoing intervention involving venous access, various techniques have been implemented to achieve hemostasis in order to reduce local access site complications, to decrease length of stay and to facilitate early ambulation. We aimed to assess the efficacy and safety of fellow's stitch using "fisherman's knot" (figure of Z ... -10-French)-Venous-Hemostasis.">Read more >>

Cardiol Res (Cardiology research)
[2019, 10(5):303-308]

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Pattern of un-operated Grown Up Congenital Heart (GUCH) patients presenting to a Tertiary Care Cardiac Institute of Punjab.

Abdul Razzaq Mughal, Rubina Tousif, Asif Rashid Alamgir, Anjum Jalal,

Objectives:To identify the pattern of un-operated grown up congenital heart defects at our tertiary care cardiac institute. Methods:This is a prospective observational study. All un-operated GUCH patients who presented to Faisalabad Institute of Cardiology (FIC) from May 2017 to 30th July 2017 were enrolled. Diagnosis was established on Transthoracic Echocardiography ... Read more >>

Pak J Med Sci (Pakistan journal of medical sciences)
[2019, 35(4):1066-1071]

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Evaluation of Flow Pattern in the Ascending Aorta in Patients with Repaired Tetralogy of Fallot Using Four-Dimensional Flow Magnetic Resonance Imaging.

Suji Lee, Young Jin Kim, Jo Won Jung, Jae Young Choi, Han Ki Park, Yu Rim Shin, Byung Wook Choi,

OBJECTIVE:To evaluate flow pattern characteristics in the ascending aorta (AA) with four-dimensional (4D)-flow MRI and to determine predictors of aortic dilatation late after tetralogy of Fallot (TOF) repair. MATERIALS AND METHODS:This study included 44 patients with repaired TOF (25 males and 19 females; mean age, 28.9 ± 8.4 years) and ... Read more >>

Korean J Radiol (Korean journal of radiology)
[2019, 20(9):1334-1341]

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Surgical Rescue After Failed Percutaneous Closure of an Aorto-Atrial Tunnel.

Federica Caldaroni, Mauro Lo Rito, Antonio Saracino, Alessandro Varrica, Luca Giugno, Alessandro Giamberti, Alessandro Frigiola,

Congenital sinus of Valsalva aneurysm is a rare disorder, mostly involving the right and noncoronary sinuses, in which intracardiac rupture is more likely foreseen into the right chambers. Because of the unfavorable prognosis, which includes heart failure and sudden death, detection itself is an indication for treatment, which may be ... Read more >>

World J Pediatr Congenit Heart Surg (World journal for pediatric & congenital heart surgery)
[2019, :2150135118802802]

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2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias: Executive summary.

Edmond M Cronin, Frank M Bogun, Philippe Maury, Petr Peichl, Minglong Chen, Narayanan Namboodiri, Luis Aguinaga, Luiz Roberto Leite, Sana M Al-Khatib, Elad Anter, Antonio Berruezo, David J Callans, Mina K Chung, Phillip Cuculich, Andre d'Avila, Barbara J Deal, Paolo Della Bella, Thomas Deneke, Timm-Michael Dickfeld, Claudio Hadid, Haris M Haqqani, G Neal Kay, Rakesh Latchamsetty, Francis Marchlinski, John M Miller, Akihiko Nogami, Akash R Patel, Rajeev Kumar Pathak, Luis C Saenz Morales, Pasquale Santangeli, John L Sapp, Andrea Sarkozy, Kyoko Soejima, William G Stevenson, Usha B Tedrow, Wendy S Tzou, Niraj Varma, Katja Zeppenfeld,

Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to sustained ventricular tachycardia and fibrillation. Rapid developments have taken place over the past decade in our understanding of these arrhythmias and in our ability to diagnose and ... Read more >>

J Arrhythm (Journal of arrhythmia)
[2020, 36(1):1-58]

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Rupture of a Type B Aortic Dissection in a Postpartum Patient with Marfan Syndrome.

Elizabeth Patberg, Jennifer Duffy, Afshan B Hameed,

Background  Pregnant women with Marfan syndrome (MFS) are known to be at increased risk of aortic dissection; however, cases of aortic rupture are extremely rare. There is lack of consensus on the exact site and size of aortic diameter measurement that increases this risk, and whether this applies to both ... Read more >>

AJP Rep (AJP reports)
[2019, 9(3):e256-e261]

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Congenital Aortic Valve Stenosis.

Gautam K Singh,

Aortic valve stenosis in children is a congenital heart defect that causes fixed form of hemodynamically significant left ventricular outflow tract obstruction with progressive course. Neonates and young infants who have aortic valve stenosis, usually develop congestive heart failure. Children and adolescents who have aortic valve stenosis, are mostly asymptomatic, ... Read more >>

Children (Basel) (Children)
[2019, 6(5):]

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Surgical treatment of mild to moderately dilated ascending aorta in bicuspid aortic valve aortopathy: the art of safety and simplicity.

Peng Zhu, Pengyu Zhou, Xiao Ling, Bright Eric Ohene, Xiao Ming Bian, Xiaoxiao Jiang,

BACKGROUND:Evaluate the safety and efficacy of our modified technique of the extravascular procedure for treating mild to moderately dilated ascending aorta in patients with bicuspid aortic valve (BAV) aortopathy. METHODS:From January 2015 to December 2018,119 consecutive patients with BAV and ascending aorta dilatation (dimension 40 mm~ 45 mm) were diagnosed in our institution. ... Read more >>

J Cardiothorac Surg (Journal of cardiothoracic surgery)
[2020, 15(1):24]

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Chronic Active Epstein-Barr Virus Infection With Systemic Vasculitis and Pulmonary Arterial Hypertension in a Child.

Hongjun Ba, Lingling Xu, Huimin Peng, Yuese Lin, Xuandi Li, Huishen Wang, Youzhen Qin,

Introduction: A chronic active Epstein-Barr virus (EBV) infection (CAEBV), which is characterized by persistent "infectious mononucleosis-like" symptoms, can lead to cardiovascular complications, including coronary artery aneurysms. No published studies have reported an occurrence of chronic EB virus infection in conjunction with systemic vasculitis and pulmonary hypertension. Case Presentation: Herein, we ... Read more >>

Front Pediatr (Frontiers in Pediatrics)
[2019, 7:219]

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A practical guide to graphic communication for quality assurance, education, and patient care in echocardiography.

Gerald I Cohen,

Graphic communication (GC) is useful for continuous quality improvement (CQI), education, and patient care when in-person discussion is not possible because of geographic and schedule constraints. In echocardiography, these constraints can be mitigated by (a) capturing screenshots and device photos or videos and sharing them by email or text message, ... Read more >>

Echocardiography (Echocardiography (Mount Kisco, N.Y.))
[2019, 36(9):1747-1754]

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Non-invasive assessment of aortic stiffness and blood pressure in young Turner syndrome patients.

Danya A Fox, Kristopher T Kang, James E Potts, Timothy J Bradley, Laura L Stewart, Janis M Dionne, George G S Sandor,

Background Females with Turner syndrome (TS) carry an elevated risk of aortic dissection. The objective of the study was to assess the biophysical properties of the aorta and ambulatory blood pressure (BP) in females with TS and compare these findings to those in healthy female age-matched controls. Methods This was ... Read more >>

J. Pediatr. Endocrinol. Metab. (Journal of pediatric endocrinology & metabolism : JPEM)
[2019, 32(5):489-498]

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Closure of insufficient, native right ventricular outflow tract with AMPLATZER™ muscular ventricular septal defect occluder in a patient with tetralogy of Fallot post-Melody® valve.

Neha Bansal, Sanjeev Aggarwal, Daniel R Turner,

AMPLATZER™ muscular ventricular septal defect occluder is used commonly for off-label purposes. We describe an unusual case of a patient with tetralogy of Fallot who underwent repair with a right ventricle to pulmonary artery homograft due to abnormal coronary artery pattern. During the initial surgery, the native right ventricular outflow ... Read more >>

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2019, 12(2):159-162]

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Successful balloon valvuloplasty of a subpulmonic membrane associated with cor triatriatum dexter: a case report.

Meryem Haboub, Abdenasser Drighil,

BACKGROUND:Subpulmonic membrane as a cause of right ventricular outflow tract obstruction in patients with concordant ventriculoarterial connection and intact ventricular septum is considered to be rare. Association with cor triatriatum dexter and success of subpulmonic balloon valvuloplasty have never been reported, at least to the best of our knowledge. CASE ... Read more >>

J Med Case Rep (Journal of medical case reports)
[2019, 13(1):291]

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Primary axillary venous aneurysm in a young patient presenting with cardiac arrest.

Willythssa S Pierre-Louis, Raisa Tikhtman, Alyssa Bonta, George Meier,

Primary venous aneurysms are rare and usually asymptomatic. Venous aneurysms are manifested more frequently in the lower extremities than in the upper extremities. Primary venous aneurysms of the upper extremities are more often reported as aesthetically displeasing bulges or incidental findings. Here, we report the rare case of an axillary ... Read more >>

J Vasc Surg Cases Innov Tech (Journal of vascular surgery cases and innovative techniques)
[2019, 5(3):375-378]

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Arterial Hypertension and Unusual Ascending Aortic Dilatation in a Neonate With Acute Kidney Injury: Mechanistic Computer Modeling.

Luis Altamirano-Diaz, Andrea D Kassay, Baran Serajelahi, Christopher W McIntyre, Guido Filler, Sanjay R Kharche,

Background:Neonatal asphyxia caused kidney injury and severe hypertension in a newborn. An unusually dilatated ascending aorta developed. Dialysis and pharmacological treatment led to partial recovery of the ascending aortic diameters. It was hypothesized that the aortic dilatation may be associated with aortic stiffening, peripheral resistance, and cardiovascular changes. Mathematical modeling ... Read more >>

Front Physiol (Frontiers in Physiology)
[2019, 10:1391]

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The transition of pediatric Marfan patients to adult care: a challenge and its risks.

Veronika C Stark, Katrin Doering, Yskert von Kodolitsch, Rainer Kozlik-Feldmann, Götz C Mueller, Jakob Olfe, Meike Rybczynski, Helke Schueler, Thomas S Mir,

Background:Care for patients with Marfan syndrome (MFS) has improved substantially in recent decades. Increasing clinical knowledge and genetic analysis allow early diagnosis of the disease in childhood. Because of the earlier initiation to preventive and medical treatment, patients' life expectancy has risen. To ensure optimal care, pediatric patients require a ... Read more >>

Cardiovasc Diagn Ther (Cardiovascular diagnosis and therapy)
[2018, 8(6):698-704]

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Hybrid closure of common carotid artery perforation caused by misplaced central venous catheter.

Konrad Paczkowski, Maciej Chojnicki, Tomasz Sroka, Katarzyna Paczkowska, Katarzyna Gierat-Haponiuk, Ireneusz Haponiuk,

Postepy Kardiol Interwencyjnej (Postepy w kardiologii interwencyjnej = Advances in interventional cardiology)
[2018, 14(4):440-441]

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Sleep apnea and the impact on cardiovascular risk in patients with Marfan syndrome.

Laura Muiño-Mosquera, Fré Bauters, Karlien Dhondt, Hans De Wilde, Luc Jordaens, Katya De Groote, Daniel De Wolf, Katrien Hertegonne, Julie De Backer,

BACKGROUND:Marfan syndrome (MFS) is an inherited connective tissue disorder characterized by ectopia lentis, aortic root dilation and dissection and specific skeletal features. Obstructive sleep apnea (OSA) in MFS has been described earlier but the prevalence and its relation with the cardiovascular risk is still controversial. This study aimed to further ... Read more >>

Mol Genet Genomic Med (Molecular Genetics & Genomic Medicine)
[2019, 7(8):e805]

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Progression of aortic root dilatation and aortic valve regurgitation after the arterial switch operation.

Roel L F van der Palen, Teun van der Bom, Annika Dekker, Roula Tsonaka, Nan van Geloven, Irene M Kuipers, Thelma C Konings, Lukas A J Rammeloo, Arend D J Ten Harkel, Monique R M Jongbloed, Dave R Koolbergen, Barbara J M Mulder, Mark G Hazekamp, Nico A Blom,

OBJECTIVE:To study neo-aortic growth and the evolution of neo-aortic valve regurgitation (AR) in patients with transposition of the great arteries (TGA) after arterial switch operation (ASO) from newborn to adulthood and to identify patients at risk. METHODS:Neo-aortic dimensions (annulus/root/sinotubular junction) and neo-aortic valve regurgitation were assessed serially in 345 patients ... Read more >>

Heart (Heart (British Cardiac Society))
[2019, 105(22):1732-1740]

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Management of Childhood Headache in the Emergency Department. Review of the Literature.

Umberto Raucci, Nicoletta Della Vecchia, Chiara Ossella, Maria Chiara Paolino, Maria Pia Villa, Antonino Reale, Pasquale Parisi,

Headache is the third cause of visits to pediatric emergency departments (ED). According to a systematic review, headaches in children evaluated in the ED are primarily due to benign conditions that tend to be self-limiting or resolve with appropriate pharmacological treatment. The more frequent causes of non-traumatic headache in the ... Read more >>

Front Neurol (Frontiers in neurology)
[2019, 10:886]

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In vivo characterization of doxycycline-mediated protection of aortic function and structure in a mouse model of Marfan syndrome-associated aortic aneurysm.

Jason Z Cui, Ling Lee, Xiaoye Sheng, Fanny Chu, Christine P Gibson, Taline Aydinian, David C Walker, George G S Sandor, Pascal Bernatchez, Glen F Tibbits, Cornelis van Breemen, Mitra Esfandiarei,

Aortic aneurysm is the most life-threatening complication in Marfan syndrome (MFS) patients. Doxycycline, a nonselective matrix metalloproteinases inhibitor, was reported to improve the contractile function and elastic fiber structure and organization in a Marfan mouse aorta using ex vivo small chamber myography. In this study, we assessed the hypothesis that ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):2071]

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