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Pediatric Second Degree Atrioventricular Block

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Complete Fetal Atrioventricular Block Associated with Maternal Autoinflammatory Diseases: Case Report and Literature Review.

Ali Ulas Tugcu, Deniz Anuk Ince, Sertac Esin, Ozden Turan, Ilkay Erdogan, Ayse Ecevit,

Acta Cardiol Sin (Acta Cardiologica Sinica)
[2020, 36(1):72-75]

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Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience.

Roberto Mijangos-Vázquez, Amal El-Sisi, Juan P Sandoval Jones, José A García-Montes, Rogelio Hernández-Reyes, Rodina Sobhy, Antoine Abdelmassih, Mohammed M Soliman, Safaa Ali, Tatiana Molina-Sánchez, Carlos Zabal,

Objectives:To demonstrate safety and efficacy of using different generations of softer Amplatzer™ devices for ventricular septal defect (VSD) closure to avoid serious complications at follow-up. Background:Transcatheter closure of perimembranous ventricular septal defects (PmVSD) is a well-established procedure; however, it is associated with unacceptable incidence of complete heart block. Great advantages ... Read more >>

J Interv Cardiol (Journal of Interventional Cardiology)
[2020, 2020:8948249]

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Isolated anti-Ro/La antibody-negative fetal complete atrioventricular block: a case report.

Huan-Huan Huo, Ya-Juan Wei, Yan-Hua Qi, Bao-Min Liu,

Chin. Med. J. (Chinese medical journal)
[2020, 133(1):97-98]

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Simultaneous dual AV node antegrade conduction (2 for 1) and lower common pathway (2-1) block illustrate AVNRT physiology.

Balaram Krishna Hanumanthu, Andrew Krummerman, Michael Grushko,

We report a rare case of spontaneous initiation of Atrioventricular nodal reentry tachycardia (AVNRT) via 2 for 1 phenomenon, into a 2:1 AV block due to lower common pathway block and finally transition to 1:1 tachycardia. The premature atrial p wave traverses down both the fast and slow pathway simultaneously ... Read more >>

Indian Pacing Electrophysiol J (Indian pacing and electrophysiology journal)
[2020, 20(2):70-72]

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Late Presentation of a Congenitally Corrected Transposition of Great Arteries and Hemodynamically Balanced Ventricles Associated with a Large Ventricular Septal Defect and Severe Pulmonary Stenosis: A Case Report and a Multi-Imaging Approach.

Khaled Elenizi, Rasha Alharthi, Anthony Matta, Abdulrahman Aljuayli, Michel Galinier,

BACKGROUND Congenitally corrected transposition of great arteries (ccTGA) represents a distinct rare group of congenital heart diseases. Survival of unoperated ccTGA in the presence of large ventricular septal defect (VSD) is exceptional. Furthermore, late presentation of such patients in the absence of severe pulmonary hypertension or severe systemic right ventricle ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e920822]

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Transcatheter Device Closure of Perimembranous Ventricular Septal Defect in Pediatric Patients: Long-Term Outcomes.

Jayal Hasmukhbhai Shah, Sanket Pravinchandra Saraiya, Tushar Sudhakarrao Nikam, Mukesh Jitendra Jha,

Aims:The aim of this study is to evaluate the safety and efficacy of transcatheter device closure of perimembranous ventricular septal defects in pediatric patients at long-term follow-up. Materials and Methods:We prospectively studied 376 patients with perimembranous VSDs between September 2008 and December 2015 who underwent percutaneous closure at our center. ... Read more >>

Heart Views (Heart views : the official journal of the Gulf Heart Association)
[2020, 21(1):17-21]

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Review Of The Safety, Efficacy And Tolerability Of Fingolimod In The Treatment Of Pediatric Patients With Relapsing-Remitting Forms Of Multiple Sclerosis (RRMS).

Jenny Feng, Mary Rensel,

Pediatric-onset multiple sclerosis (POMS) is an immune-mediated, demyelinating, neurodegenerative disease that accounts for 3-5% of all multiple sclerosis (MS) cases. Although evidence suggests that it has similar risk factors and disease pathophysiology as adult-onset MS (AOMS), there are distinctive features in disease characteristics and patient demographics of POMS that require ... Read more >>

Pediatric Health Med Ther (Pediatric health, medicine and therapeutics)
[2019, 10:141-146]

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Pediatrics and GUCHs.

J Arrhythm (Journal of Arrhythmia)
[2019, 35(Suppl 1):693-711]

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Value of Troponin Testing for Detection of Heart Disease in Previously Healthy Children.

Audrey Dionne, John N Kheir, Lynn A Sleeper, Jesse J Esch, Roger E Breitbart,

Background Troponin levels are frequently obtained in pediatric patients, but the benefit remains unclear. Methods and Results This retrospective study included 1993 patients aged 0 to 21 years without history of cardiac disease in whom troponin levels were obtained during clinical evaluation of cardiac and noncardiac presentations. Troponin was elevated (≥0.1 ng/mL) ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2020, 9(4):e012897]

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Arrhythmia and/or Cardiomyopathy Related to Maternal Autoantibodies: Descriptive Analysis of a Series of 16 Cases From a Single Center.

Benzhen Wang, Sujuan Hu, Degong Shi, Zhen Bing, Zipu Li,

Objective: To describe the clinical characteristics of maternal autoantibody-mediated arrhythmia and/or cardiomyopathy, and to explore the therapeutic role of glucocorticoids in these diseases. Methods: This was a retrospective observational study of 2 fetuses and 14 children who presented with autoantibody-mediated arrhythmia and/or cardiomyopathy in our hospital from September 2010 to ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:465]

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Results of a phase 1 multicentre investigation of dexmedetomidine bolus and infusion in corrective infant cardiac surgery.

Athena F Zuppa, Susan C Nicolson, Nicole S Wilder, Juan C Ibla, Erin A Gottlieb, Kristin M Burns, Mario Stylianou, Felicia Trachtenberg, Hua Ni, Tera H Skeen, Dean B Andropoulos, ,

BACKGROUND:Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for steady-state DEX plasma levels; and ... Read more >>

Br J Anaesth (British journal of anaesthesia)
[2019, 123(6):839-852]

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DSP p.(Thr2104Glnfs*12) variant presents variably with early onset severe arrhythmias and left ventricular cardiomyopathy.

Krista Heliö, Tiia Kangas-Kontio, Sini Weckström, Sari U M Vanninen, Katriina Aalto-Setälä, Tero-Pekka Alastalo, Samuel Myllykangas, Tiina M Heliö, Juha W Koskenvuo,

BACKGROUND:Dilated cardiomyopathy (DCM) is a condition characterized by dilatation and systolic dysfunction of the left ventricle in the absence of severe coronary artery disease or abnormal loading conditions. Mutations in the titin (TTN) and lamin A/C (LMNA) genes are the two most significant contributors in familial DCM. Previously mutations in ... Read more >>

BMC Med. Genet. (BMC medical genetics)
[2020, 21(1):19]

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Health-related quality of life in children and adolescents undergoing intraoperative device closure of isolated perimembranous ventricular septal defects in southeastern China.

Jiang-Shan Huang, Shu-Ting Huang, Kai-Peng Sun, Zhi-Nuan Hong, Liang-Wan Chen, Yur-Ren Kuo, Qiang Chen,

OBJECTIVES:To investigate the health-related quality of life (HRQOL) in children and adolescents who underwent intraoperative device closure of perimembranous ventricular septal defects (pmVSDs). METHODS:From October 2017 to January 2018, a total of 126 children and adolescents with isolated pmVSDs who underwent intraoperative device closure were enrolled in this study. We ... Read more >>

J Cardiothorac Surg (Journal of cardiothoracic surgery)
[2019, 14(1):218]

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Zero Fluoroscopy During Ablation of Right-Sided Supraventricular Tachycardia Substrates in a Pediatric Population - Initial Experience in Taiwan.

Wei-Chieh Tseng, Mei-Hwan Wu, Chun-Wei Lu, Kun-Lang Wu, Jou-Kou Wang, Ming-Tai Lin, Chun-An Chen, Shuenn-Nan Chiu,

Background:Zero fluoroscopy during ablation of arrhythmias has been introduced to reduce radiation exposure. However, the safety, feasibility and efficacy of the technique in pediatric populations have yet to be delineated. Objectives:To investigate the safety, feasibility and effectiveness of zero fluoroscopic-guided transcatheter ablation of right-sided supraventricular tachycardia substrates in a pediatric ... Read more >>

Acta Cardiol Sin (Acta Cardiologica Sinica)
[2019, 35(5):476-483]

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Junctional ectopic tachycardia in infants and children.

Ranjit I Kylat, Ricardo A Samson,

Tachyarrhythmias originating in the atrioventricular (AV) node and AV junction including the bundle of His complex (BH) are called junctional tachycardia (JT) or junctional ectopic tachycardia (JET). Congenital JET (CJET) is a rare arrhythmia that occurs in patients without a preceding cardiac surgery and can be refractory to medical therapy ... Read more >>

J Arrhythm (Journal of arrhythmia)
[2020, 36(1):59-66]

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Baroreflex Sensitivity Predicts Response to Metoprolol in Children With Vasovagal Syncope: A Pilot Study.

Chunyan Tao, Xueying Li, Chaoshu Tang, Hongfang Jin, Junbao Du,

Objective: To explore the role of baroreflex sensitivity (BRS) in the head-up tilt test (HUTT) in predicting the therapeutic response of vasovagal syncope (VVS) patients to metoprolol. Materials and Methods: Vasovagal syncope patients treated with metoprolol were enrolled in this study and were classified as responders or non-responders according to ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2019, 13:1329]

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Severe Cardiorespiratory and Neurologic Symptoms in a Neonate due to Mepivacaine Intoxication.

Maurike de Groot-van der Mooren, Sabine Quint, Ingmar Knobbe, Doug Cronie, Mirjam van Weissenbruch,

Local anesthesia with mepivacaine is used for vaginal deliveries and for minor surgeries of the vagina and perineum as repair of an episiotomy or perineal laceration. Neonatal intoxication caused by local anesthesia with mepivacaine for maternal episiotomy has been rarely reported. We present a case of a term female infant ... Read more >>

Case Rep Pediatr (Case reports in pediatrics)
[2019, 2019:4013564]

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Cannabis-Induced Third-Degree AV Block.

Jan M Van Keer,

Background:Cannabis (marijuana) is the most widely consumed illicit drug in Europe. However, many are unaware of its potential cardiovascular side effects. Case Report:A 19-year-old man presented to the emergency department with palpitations and presyncope after smoking cannabis. A third-degree atrioventricular block (complete heart block) was diagnosed. We believe cannabis exposure ... Read more >>

Case Rep Emerg Med (Case Reports in Emergency Medicine)
[2019, 2019:5037356]

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Rare Conduction Abnormality in a Four-year-old Child with Carbamazepine Acute Poisoning.

Cristina Iolanda Vivisenco, Coriolan Emil Ulmeanu,

Background:Cardiac conduction abnormalities are reported after ingestion of a toxic dose of carbamazepine. Case presentation:We describe the case of a four-year-old child with carbamazepine acute poisoning who developed reversible synoatrial block along with neurological toxic signs, despite a serum level of carbamazepine close to the upper limit of the therapeutic ... Read more >>

Maedica (Buchar) (Maedica)
[2019, 14(2):165-168]

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Management of asymptomatic ventricular preexcitation.

Shaun Mohan, Seshadri Balaji,

An incidental discovery of Wolff Parkinson White (WPW) pattern on the electrocardiogram (ECG) is not an infrequent finding facing the physician. Most patients discovered incidentally are asymptomatic and it is hard to justify further management of such patients given the time-honored adage to "first do no harm." However, this finding ... Read more >>

Indian Pacing Electrophysiol J (Indian pacing and electrophysiology journal)
[2019, 19(6):232-239]

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Successful cardiopulmonary resuscitation following minimally invasive pectus excavatum repair: A case report.

Kyle J Glithero, John J Tackett, Kenneth DeMason, Cathy A Burnweit,

INTRODUCTION:Pectus excavatum is the most common congenital chest wall deformity. The minimally invasive repair of pectus excavatum (MIRPE) is the most commonly practiced method of surgical treatment and there is concern that the pectus bar will prevent effective CPR. There are no recorded cases of successful cardiopulmonary resuscitation with pectus ... Read more >>

Int J Surg Case Rep (International journal of surgery case reports)
[2019, 65:255-258]

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Resolution of cardiomyopathy with catheter ablation of right anterolateral accessory pathway.

Oholi Tovia-Brodie, Archana Ramireddy, Amit Badiye, Raul D Mitrani,

HeartRhythm Case Rep (HeartRhythm case reports)
[2019, 5(10):516-519]

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Long-term follow-up and outcomes of discrete subaortic stenosis resection in children.

Lulu Abushaban, Babu Uthaman, John Puthur Selvan, Mustafa Al Qbandi, Prem N Sharma, Thinakar Vel Mariappa,

Background:Studies of long-term outcomes of discrete subaortic stenosis (DSS) are rare. Therefore, we reviewed the long-term outcomes of subaortic membrane resection in children with isolated DSS over 16 years from a single institution. Materials and Methods:We retrospectively reviewed the records of patients (n = 27) who underwent resection of DSS ... Read more >>

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2019, 12(3):212-219]

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Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level.

Katherine G Palmer, Jacob A Lebin, Michael T Cronin, Suzan S Mazor, Rebekah A Burns,

INTRODUCTION:A species of hawthorn, Crataegus mexicana (tejocote), has been marketed as a weight-loss supplement that is readily available for purchase online. While several hawthorn species have shown clinical benefit in the treatment of heart failure owing to their positive inotropic effects, little is known about hawthorn, and tejocote in particular, ... Read more >>

J Med Toxicol (Journal of medical toxicology : official journal of the American College of Medical Toxicology)
[2019, 15(4):295-298]

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Effects of perioperative transcutaneous electrical acupoint stimulation on monocytic HLA-DR expression in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass: study protocol for a double-blind randomized controlled trial.

Wen-Ting Chen, Jin-Feng Wei, Lan Wang, Deng-Wen Zhang, Wei Tang, Jian Wang, Yue Yong, Jing Wang, Ya-Lan Zhou, Lan Yuan, Guo-Qiang Fu, Sheng Wang, Jian-Gang Song,

BACKGROUND:Cardiac surgery involving cardiopulmonary bypass (CPB) is known to be associated with a transient postoperative immunosuppression. When severe and persistent, this immune dysfunction predisposes patients to infectious complications, which contributes to a prolonged stay in the intensive care unit (ICU), and even mortality. Effective prevention and treatment methods are still ... Read more >>

Trials (Trials)
[2019, 20(1):789]

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