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Pediatric Rheumatic Heart Disease

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Simultaneous Occurrence of Sydenham Chorea with Erythema Marginatum: A Case of Rheumatic Fever.

Temesgen Tsega Desta, Mulugeta Naizgi,

Background:Rheumatic fever continues to be a major public health problem in the developing world, being responsible for many morbidities and mortalities. Were it not for its serious effects on the cardiovascular system, and to some extent on the central nervous system, the disease might not have significant consequences. The central nervous system involvement is ... Read more >>

Pediatric Health Med Ther (Pediatric health, medicine and therapeutics)
[2020, 11:55-58]

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Alterations in the Nervous System and Gut Microbiota after β-Hemolytic Streptococcus Group A Infection-Characteristics and Diagnostic Criteria of PANDAS Recognition.

Jacek Baj, Elżbieta Sitarz, Alicja Forma, Katarzyna Wróblewska, Hanna Karakuła-Juchnowicz,

The objective of this paper is to review and summarize conclusions from the available literature regarding Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS). The authors have independently reviewed articles from 1977 onwards, primarily focusing on the etiopathology, symptoms, differentiation between similar psychiatric conditions, immunological reactions, alterations in the ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(4):]

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Assessment of traditional and non-traditional risk factors for premature atherosclerosis in children with juvenile dermatomyositis and pediatric controls.

Dawn M Wahezi, Emily J Liebling, Jaeun Choi, Marija Dionizovik-Dimanovski, Qi Gao, Jillian Parekh,

BACKGROUND:Children with juvenile dermatomyositis (JDM), the most common inflammatory myopathy of childhood, may be at increased risk of premature atherosclerosis given a host of traditional and non-traditional risk factors. The primary aim of this study was to determine the underlying frequency of premature atherosclerosis in children with JDM compared to ... Read more >>

Pediatr Rheumatol Online J (Pediatric Rheumatology Online Journal)
[2020, 18(1):25]

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Comprehensive Assessment of Orofacial Health and Disease Related Parameters in Adolescents with Juvenile Idiopathic Arthritis-A Cross-Sectional Study.

Cordula Leonie Merle, Robin Hoffmann, Jan Schmickler, Michael Rühlmann, Nadia Challakh, Rainer Haak, Gerhard Schmalz, Dirk Ziebolz,

BACKGROUND:The aim of this cross-sectional study was to investigate oral health and functional status of adolescents with juvenile idiopathic arthritis (JIA) and its possible link to disease specific parameters. METHODS:Patients with JIA were recruited (November 2012-October 2014) and disease specific information was extracted from patients' records. Oral examination included: dental ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(2):]

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Pediatric-onset systemic lupus erythematosus with coronary artery dilation: A case report.

Hui Zhang, Lijuan Zhang, Nan Guo,

INTRODUCTION:Though pediatric-onset systemic lupus erythematosus (SLE) is at high risk of coronary artery involvement, coronary artery dilation appears to be a rare characteristic of pediatric-onset SLE. In this article, we described 1 pediatric-onset SLE patient with coronary artery dilation at the diagnosis of SLE, in order to better diagnose and ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(5):e18946]

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Clinical characteristics of pediatric patients with first-attack acute rheumatic fever following the updated guideline.

Mühlike Güler, Fuat Laloğlu, Haşim Olgun, Naci Ceviz,

Aim:To evaluate the clinical features of children diagnosed as having acute rheumatic fever between June 2015 and November 2018, and the changes observed in patient groups in comparison with data obtained in previous years. The diagnosis of acute rheumatic fever was made using the updated Jones criteria. Material and Methods:The ... Read more >>

Turk Pediatri Ars (Turk pediatri arsivi)
[2019, 54(4):220-224]

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Childhood-onset Takayasu Arteritis.

Florence A. Aeschlimann, Marinka Twilt, Rae S. M. Yeung,

Childhood-onset Takayasu Arteritis (cTAK) is a rare, large-vessel type of vasculitis seen in children, mainly affecting the aorta and its major branches. Clinical manifestations are often severe and arise as a result of systemic and local inflammation, along with end-organ ischemia. Disease flares are common and the disease burden is ... Read more >>

(European Journal of Rheumatology)
[2020, 7(Suppl 1):S58-S66]

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Changes in valvular regurgitation in mid-term follow-up of children with first attack acute rheumatic fever: first evaluation after the updated Jones criteria.

Muhlike Güler, Fuat Laloğlu, Naci Ceviz,

AIM:In present study, we aimed to evaluate the changes in valvular regurgitations in mid-term follow-up of children with first attack acute rheumatic fever diagnosed after updated Jones criteria. MATERIALS AND METHODS:The medical records of the children diagnosed with acute rheumatic fever between June 2015 and November 2018 were evaluated retrospectively. ... Read more >>

Cardiol Young (Cardiology in the young)
[2020, 30(3):369-371]

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Movement disorders in patients with alternating hemiplegia: "Soft" and "stiff" at the same time.

Eleni Panagiotakaki, Diane Doummar, Erika Nogue, Nicolas Nagot, Gaetan Lesca, Florence Riant, Sophie Nicole, Charlene Delaygue, Marie Anne Barthez, Marie Cécile Nassogne, Anne Dusser, Louis Vallée, Thierry Billette, Marie Bourgeois, Christine Ioos, Cyril Gitiaux, Cécile Laroche, Mathieu Milh, Vincent Des Portes, Alexis Arzimanoglou, Agathe Roubertie, ,

OBJECTIVE:To assess nonparoxysmal movement disorders in ATP1A3 mutation-positive patients with alternating hemiplegia of childhood (AHC). METHODS:Twenty-eight patients underwent neurologic examination with particular focus on movement phenomenology by a specialist in movement disorders. Video recordings were reviewed by another movement disorders specialist and data were correlated with patients' characteristics. RESULTS:Ten patients ... Read more >>

Neurology (Neurology)
[2020, :]

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Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study.

Joel M Guthridge, Rufei Lu, Ly Thi-Hai Tran, Cristina Arriens, Teresa Aberle, Stan Kamp, Melissa E Munroe, Nicolas Dominguez, Timothy Gross, Wade DeJager, Susan R Macwana, Rebecka L Bourn, Stephen Apel, Aikaterini Thanou, Hua Chen, Eliza F Chakravarty, Joan T Merrill, Judith A James,

Background:The clinical and pathologic diversity of systemic lupus erythematosus (SLE) hinders diagnosis, management, and treatment development. This study addresses heterogeneity in SLE through comprehensive molecular phenotyping and machine learning clustering. Methods:Adult SLE patients (n = 198) provided plasma, serum, and RNA. Disease activity was scored by modified SELENA-SLEDAI. Twenty-nine co-expression module scores ... Read more >>

EClinicalMedicine (EClinicalMedicine)
[2020, 20:100291]

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Aorto-Mitral Patch Enlargement for Elective Substantial Double Valve Upsizing.

Daniel Fudulu, Mustafa Zakkar, Serban Stoica,

Reconstruction of the intervalvular fibrosa is normally associated with endocarditis and the surgical principles are well established. Here, we describe how these principles are further extended and applied for the elective enlargement of the aorto-mitral continuity. Our aim was to achieve double valve upsizing in noninfective conditions. The first patient ... Read more >>

World J Pediatr Congenit Heart Surg (World journal for pediatric & congenital heart surgery)
[2020, 11(1):101-104]

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Echocardiographic screening for rheumatic heart disease in Turkish school children.

Semra Atalay, Ercan Tutar, Tayfun Uçar, Seda Topçu, Serdal K Köse, Melih T Doğan,

Cardiol Young (Cardiology in the young)
[2020, 30(1):151]

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Mystery still unresolved: Untouched "Blue heart" presenting at 40yrs of age.

Sanjeev H Naganur, Ashish Tiwari, C R Pruthvi,

The modern-day surgical techniques and strategies have changed the outlook of patients with dextro-transposition of great arteries (d-TGA). The survival of an unrepaired d-TGA into late adulthood is difficult to explain. Even when large intracardiac shunts are present, it still remains a lethal cyanotic congenital heart disease if it is ... Read more >>

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2020, 13(1):72-74]

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Increased Cancer Incidence Following up to 15 Years after Cardiac Catheterization in Infants under One Year between 1980 and 1998-A Single Center Observational Study.

Heiko Stern, Michael Seidenbusch, Alexander Hapfelmeier, Christian Meierhofer, Susanne Naumann, Irene Schmid, Claudia Spix, Peter Ewert,

OBJECTIVE:To evaluate the incidence of cancer within the first 15 years of life in children who underwent cardiac catheterization under the age of one year. METHODS:In this retrospective, single center study, 2770 infants (7.8% with trisomy 21) were studied. All infants underwent cardiac catheterization under one year of age between ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(2):]

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Voices behind the Statistics: A Systematic Literature Review of the Lived Experience of Rheumatic Heart Disease.

Emma Haynes, Alice Mitchell, Stephanie Enkel, Rosemary Wyber, Dawn Bessarab,

In Australia, Aboriginal children almost entirely bear the burden of acute rheumatic fever (ARF) which often leads to rheumatic heart disease (RHD), a significant marker of inequity in Indigenous and non-Indigenous health experiences. Efforts to eradicate RHD have been unsuccessful partly due to lack of attention to voices, opinions and ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(4):]

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A Bayesian Spatiotemporal Analysis of Pediatric Group A Streptococcal Infections.

Angela Wang, Andrew M Fine, Erin Buchanan, Mark Janko, Lise E Nigrovic, Paul M Lantos,

Background:Pharyngitis due to group A Streptococcus (GAS) is a common pediatric infection. Physicians might diagnose GAS pharyngitis more accurately when given biosurveillance information about GAS activity. The availability of geographic GAS testing data may be able to assist with real-time clinical decision-making for children with throat infections. Methods:GAS rapid antigen ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(12):ofz524]

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Focus on Cardiologic Findings in 30 Children With PANS/PANDAS: An Italian Single-Center Observational Study.

Manuel Murciano, Davide Maria Biancone, Giulia Capata, Isabella Tristano, Vanessa Martucci, Cristiana Alessia Guido, Silvia Anaclerio, Lorenzo Loffredo, Anna Maria Zicari, Marzia Duse, Alberto Spalice,

Objective: Cardiac involvement in PANS has not been clarified relying on the scientific literature available until today. It is known that streptococcal infections play a role in the etiology of a great number of diseases including Sydenham chorea and rheumatic fever, among others. Based on the suspected pathogenesis of PANDAS ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:395]

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Pediatric antiphospholipid syndrome.

Jacqueline A Madison, Yu Zuo, Jason S Knight,

Despite its potential to cause significant morbidity in children, pediatric antiphospholipid syndrome (APS) is an understudied condition. In this review, we will cover what is known about pediatric APS epidemiology and how the clinician might approach the diagnosis of pediatric APS. We will highlight similarities and differences with the adult ... Read more >>

Eur J Rheumatol (European journal of rheumatology)
[2019, :1-10]

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Oral lesions in patients with primary Sjögren's syndrome. A case-control cross-sectional study.

J Serrano, R-M López-Pintor, M Fernández-Castro, L Ramírez, M Sanz, E Casañas, J-A García, S Recuero, C Bohorquez, G Hernández,

BACKGROUND:To evaluate the presence of oral lesions in a group of patients with primary Sjögren's syndrome (pSS) and compare these results with a matched control group (CG). MATERIAL AND METHODS:An observational cross-sectional study was conducted. 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) diagnosed according to the American ... Read more >>

Med Oral Patol Oral Cir Bucal (Medicina oral, patologia oral y cirugia bucal)
[2020, 25(1):e137-e143]

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Trends in Ultrasound Use in Low and Middle Income Countries: A Systematic Review.

Kelsey A Stewart, Sergio M Navarro, Sriharsha Kambala, Gail Tan, Revanth Poondla, Sara Lederman, Kelli Barbour, Chris Lavy,

Background:Evidence on recent trends regarding the impact and cost-benefits of ultrasound in resource-constrained settings is limited. This study presents a systematic review to determine recent trends in the utility and applicability of ultrasound use in low and middle income countries (LMIC). The review includes characterizing and evaluating trends in (1) ... Read more >>

Int J MCH AIDS (International journal of MCH and AIDS)
[2020, 9(1):103-120]

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Recurrent Pericarditis in Children and Adolescents.

Enrico Tombetti, Teresa Giani, Antonio Brucato, Rolando Cimaz,

Recurrent pericarditis (RP) is a clinical syndrome characterized by recurrent attacks of acute pericardial inflammation. Prognosis quoad vitam is good, although morbidity might be significant, especially in children and adolescents. Multiple potential etiologies result in RP, in the vast majority of cases through autoimmune or autoinflammatory mechanisms. Idiopathic RP is ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:419]

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Pediatric systemic lupus erythematosus patients in South Africa have high prevalence and severity of cardiac and vascular manifestations.

Michael J Harrison, Liesl J Zühlke, Laura B Lewandowski, Christiaan Scott,

BACKGROUND:Pediatric onset of systemic lupus erythematosus (SLE) is associated with major organ involvement, and African patients tend to develop more aggressive disease than patients of European descent. Although cardiovascular involvement is common in pediatric SLE, there are few published reports on the subject. This study describes the frequency and characteristics ... Read more >>

Pediatr Rheumatol Online J (Pediatric rheumatology online journal)
[2019, 17(1):76]

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Kawasaki Disease: Global Burden and Genetic Background.

Karim Elakabawi, Jing Lin, Fuyong Jiao, Ning Guo, Zuyi Yuan,

Kawasaki disease (KD) is a childhood vasculitides associated with serious coronary artery lesions. It is the most common cause of pediatric acquired heart disease in developed countries, and is increasingly reported from many rapidly industrializing developing countries. The incidence varies widely among different nations and is highest in North-East Asian ... Read more >>

Cardiol Res (Cardiology research)
[2020, 11(1):9-14]

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Echoes of Telecardiology Guideline.

Silvio Henrique Barberato, Marcelo Antônio Cartaxo Queiroga Lopes,

Arq. Bras. Cardiol. (Arquivos brasileiros de cardiologia)
[2020, 114(1):130-132]

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Treatment outcome and its predictors among patients of acute heart failure at a tertiary care hospital in Ethiopia: a prospective observational study.

Mulubirhan Tirfe, Teshome Nedi, Desalew Mekonnen, Alemseged Beyene Berha,

BACKGROUND:Acute heart failure is a rapid onset of new or worsening of signs and symptoms of heart failure that requires hospitalization or a visit to the emergency department. The aim of this study was to evaluate treatment outcome and determine factors that predict a poor treatment outcome in acute heart ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20(1):16]

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