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Pediatric Respiratory Acidosis

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Predictors of outcome in childhood Plasmodium falciparum malaria.

Harsita Patel, Claire Dunican, Aubrey J Cunnington,

Plasmodium falciparum malaria is classified as either uncomplicated or severe, determining clinical management and providing a framework for understanding pathogenesis. Severe malaria in children is defined by the presence of one or more features associated with adverse outcome, but there is wide variation in the predictive value of these features. ... Read more >>

Virulence (Virulence)
[2020, 11(1):199-221]

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Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts’ consensus statement.

Kunling Shen, Yonghong Yang, Tianyou Wang, Dongchi Zhao, Yi Jiang, Runming Jin, Yuejie Zheng, Baoping Xu, Zhengde Xie, Likai Lin, Yunxiao Shang, Xiaoxia Lu, Sainan Shu, Yan Bai, Jikui Deng, Min Lu, Leping Ye, Xuefeng Wang, Yongyan Wang, Liwei Gao,

Since the outbreak of 2019 novel coronavirus infection (2019-nCoV) in Wuhan City, China, by January 30, 2020, a total of 9692 confirmed cases and 15,238 suspected cases have been reported around 31 provinces or cities in China. Among the confirmed cases, 1527 were severe cases, 171 had recovered and been ... Read more >>

World J Pediatr (World Journal of Pediatrics)
[0, :1-9]

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Early Recognition and Treatment of Malignant Hyperthermia in Pediatric Patient during Bronchoscopy.

Warangkana Lapisatepun, Supawan Arkarattanakul,

Malignant hyperthermia is a rare pharmacogenetic disorder triggered by depolarizing muscle relaxant and potent volatile anesthetic agents. An MH crisis is an emergency and life-threatening event requiring early recognition and prompt management. Dantrolene is the specific antagonist of MH. The authors report the case of a 9-year-old boy who underwent ... Read more >>

Case Rep Anesthesiol (Case reports in anesthesiology)
[2020, 2020:6562896]

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Critical Care Education Day: A Novel, Multidisciplinary, and Interactive Critical Care Education Session for Emergency Medicine Residents.

Natalie N Htet, Alexandra June Gordon, Tsuyoshi Mitarai,

Critical care medicine (CCM) is central to emergency medicine (EM) resident education. We feel that the traditional lecture format is not the ideal way to teach EM critical care, which requires integration and prioritization of diagnostic workup and team-based resuscitation under time pressure. We describe a novel critical care education day where ... Read more >>

Cureus (Cureus)
[2020, 12(1):e6785]

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MALIGNANT HYPERTHERMIA IN A CHILD AFTER MAGNETIC RESONANCE IMAGING: A CASE REPORT.

Carlos Gustavo de Almeida, José Colleti Junior,

OBJECTIVE:To report on a case of malignant hyperthermia in a child after a magnetic resonance imaging of the skull was performed using sevoflurane anesthesia. CASE DESCRIPTION:A 3-year-old boy admitted to the pediatric intensive care unit after presenting clinical and laboratory findings consistent with unspecified viral meningoencephalitis. While the patient was ... Read more >>

Rev Paul Pediatr (Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo)
[2020, 38:e2018267]

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MANAGEMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME IN A CHILD WITH ADENOVIRUS PNEUMONIA: CASE REPORT AND LITERATURE REVIEW.

Felipe Rezende Caino de Oliveira, Krisna de Medeiros Macias, Patricia Andrea Rolli, José Colleti Junior, Werther Brunow de Carvalho,

OBJECTIVE:To report the case of a child who developed acute respiratory distress syndrome (ARDS) from a pulmonary infection by adenovirus. CASE DESCRIPTION:A female patient aged 2 years and 6 months, weighting 10,295 grams developed fever, productive cough and vomiting, later on progressing to ARDS despite initial therapy in accordance with ... Read more >>

Rev Paul Pediatr (Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo)
[2020, 38:e2018280]

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Effective and safe diet therapies for Lennox-Gastaut syndrome with mitochondrial dysfunction.

Ji-Hoon Na, Heung-Dong Kim, Young-Mock Lee,

Background:Lennox-Gastaut syndrome (LGS) is a typical intractable form of epilepsy that most often occurs between the second and sixth year of life. This study aimed to evaluate the clinical efficacy and safety of ketogenic diet therapies (DTs) for LGS with mitochondrial dysfunction. Methods:This was a retrospective study involving 20 LGS ... Read more >>

Ther Adv Neurol Disord (Therapeutic advances in neurological disorders)
[2020, 13:1756286419897813]

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Use of Sodium Bicarbonate During Pediatric Cardiac Admissions with Cardiac Arrest: Who Gets It and What Does It Do?

Rohit S Loomba, Mubbasheer Ahmed, Mubeena Abdulkarim, Enrique G Villarreal, Saul Flores,

The objectives of this study were to characterize the use of sodium bicarbonate in pediatric cardiac admissions that experience cardiac arrest, to determine sodium bicarbonate use over the years, and to determine the impact of sodium bicarbonate on length of admissions, billed charges, and inpatient mortality. A cross-sectional study was ... Read more >>

Children (Basel) (Children (Basel, Switzerland))
[2019, 6(12):]

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Late onset oxygen requirement following neonatal therapeutic hypothermia.

Mohamed El-Dib, Chelsea Munster, Eniko Szakmar, Terrie Inder, Alistair J Gunn,

AIM:To investigate the characteristics of infants with neonatal encephalopathy (NE) receiving therapeutic hypothermia (TH) who developed late onset oxygen requirement during or after rewarming. METHODS:Infants were stratified by receiving (a) new onset isolated oxygen requirements during or after rewarming; (b) no respiratory support during hospital stay; and (c) invasive and/or ... Read more >>

Acta Paediatr. (Acta paediatrica (Oslo, Norway : 1992))
[2020, :]

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Occurrence of rhabdomyolysis, serotonin syndrome, and acute respiratory distress syndrome in a child secondary to ecstasy intoxication.

Osman Yeşilbaş, Selçuk Uzuner, Çiğdem Korkmaz, Lala Nurmammadova, Ayşegül Doğan Demir,

Turk Pediatri Ars (Turk pediatri arsivi)
[2019, 54(4):281-283]

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G-mutation-in-a-Chinese-family".">Letter to the Editor: Comments on "Obesity associated with a novel mitochondrial tRNACys m.5802A>G mutation in a Chinese family".

Josef Finsterer,

In a recent article Wang et al. reported about a 9-year-old Chinese male with obesity, insulin resistance, acanthosis nigricans, hyperuricemia, and non-alcoholic fatty liver disease (NALFD) being attributed to the variant m.5802A>G in tRNA(Cys) (Bioscience Reports (2020) 40(1), BSR20192153). Pathogenicity of the variant was substantiated by documentation of perturbed stability ... G-mutation-in-a-Chinese-family".">Read more >>

Biosci. Rep. (Bioscience reports)
[2020, 40(2):]

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Pediatric extracorporeal membrane oxygenation: Our experience with single-vessel cannulation.

Muhterem Duyu, Asena Pınar Sefer,

Background:In this study, we present our experience with bicaval, dual-lumen, venovenous extracorporeal membrane oxygenation in pediatric patients with severe respiratory failure. Methods:Between September 2015 and May 2019, a total of nine pediatric patients (7 males, 2 females; median age 3.1 years; range, 0.3 to 7.4 years) hospitalized in the pediatric ... Read more >>

Turk Gogus Kalp Damar Cerrahisi Derg (Turk gogus kalp damar cerrahisi dergisi)
[2020, 28(1):92-100]

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Safety and Effectiveness of the Prolonged Treatment of Children with a Ketogenic Diet.

Jana Ruiz Herrero, Elvira Cañedo Villarroya, Juan José García Peñas, Beatriz García Alcolea, Begoña Gómez Fernández, Laura Andrea Puerta Macfarland, Consuelo Pedrón Giner,

BACKGROUND:The ketogenic diet (KD) is an effective treatment against drug-resistant epilepsy in children. The KD is a diet rich in fats that produces anticonvulsant and neuroprotective effects that reduces seizures and improves the cognitive state. Nevertheless, it can produce side effects that sometimes can be serious. Further, the effect on ... Read more >>

Nutrients (Nutrients)
[2020, 12(2):]

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Fluid Therapy For Pediatric Patients With Diabetic Ketoacidosis: Current Perspectives.

Muralidharan Jayashree, Vijai Williams, Rajalakshmi Iyer,

Diabetic ketoacidosis (DKA) is a preventable life-threatening complication of type 1 diabetes. Fluids form a crucial component of DKA therapy, goals being the restoration of intravascular, interstitial and intracellular compartments. Hydration reduces hyperglycemia by decreased counter-regulatory hormones, enhanced renal glucose clearance and augmented insulin sensitivity. However, for the last several ... Read more >>

Diabetes Metab Syndr Obes (Diabetes, metabolic syndrome and obesity : targets and therapy)
[2019, 12:2355-2361]

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Successful Management of Airway and Esophageal Foreign Body Obstruction in a Child.

Naoki Yogo, Chiaki Toida, Takashi Muguruma, Masayasu Gakumazawa, Mafumi Shinohara, Ichiro Takeuchi,

Foreign body asphyxia is a serious clinical problem with high morbidity and mortality rates. It is relatively common among children, especially those younger than 3 years, because they have a high risk of aspirating foreign bodies owing to their tendency to place objects in their mouth and lack of a ... Read more >>

Case Rep Emerg Med (Case reports in emergency medicine)
[2019, 2019:6858171]

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Continuous venovenous hemodiafiltration in the treatment of newborns with an inborn metabolic disease: a single center experience

Hasan Akduman, Emel Okulu, Fatma Tuba Eminoğlu, Tanıl Kendirli, Gaffari Tunç, Ebru Azapağası, Oktay Perk, Ömer Erdeve, Begüm Atasay, Saadet Arsan,

Background/aim:Most inborn metabolic diseases are diagnosed during the neonatal period. The accumulation of toxic metabolites may cause acute metabolic crisis with long-term neurological dysfunction and death. Renal replacement therapy (RRT) modalities allow the efficient removal of toxic metabolites. In this study, we reviewed our experience with continuous venovenous hemodiafiltration (CVVHDF) ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, 50(1):12-17]

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Risk factors for BiPAP failure as an initial management approach in moderate to late preterm infants with respiratory distress.

Heekwon Son, Eui Kyung Choi, Kyu Hee Park, Jeong Hee Shin, Byung Min Choi,

Clin Exp Pediatr (Clinical and experimental pediatrics)
[2020, 63(2):63-65]

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Status Epilepticus as a Consequence of Hemophagocytic Lymphohistiocytosis in a Previously Healthy Infant.

Saeed M Nassar, Muath A AlBattah, Ahmad A Bukhari, Aryaf Alslimah, Assalh A Nahass,

Hemophagocytic lymphohistiocytosis (HLH) is a rare and fatal entity with an incidence rate of 1.2 cases per million people per year. HLH is explained as a highly destructive inflammatory consequence of rampant hypercytokinemia due to excessive lymphocyte-mediated activation of macrophages and histiocytes. Primary HLH is a product of genetic dysfunction ... Read more >>

Cureus (Cureus)
[2020, 12(1):e6824]

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Effectiveness of nCPAP for moderate preterm infants compared to BiPAP: A Randomized, Controlled Non-Inferiority Trial.

Mi-Ji Lee, Eui Kyung Choi, Kyu Hee Park, Jeonghee Shin, Byung Min Choi,

BACKGROUND:Bilevel positive airway pressure (BiPAP) has recently been used in preterm infants with respiratory distress as an alternative to nasal continuous positive airway pressure (nCPAP) because, theoretically, BiPAP is thought to be more effective than nCPAP. However, the results of some studies comparing nCPAP with BiPAP as the initial respiratory ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2020, 62(1):59-64]

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Genotype-phenotype correlation and description of two novel mutations in Iranian patients with glycogen storage disease 1b (GSD1b).

Maryam Eghbali, Maryam Abiri, Saeed Talebi, Zahra Noroozi, Marjan Shakiba, Parastoo Rostami, Hosein Alimadadi, Mehri Najafi, Fatemeh Yazarlou, Ali Rabbani, Mohammad Hossein Modarressi,

BACKGROUND:Glycogen storage disease (GSD) is a rare inborn error of the synthesis or degradation of glycogen metabolism. GSD1, the most common type of GSD, is categorized into GSD1a and GSD1b which caused by the deficiency of glucose-6-phosphatase (G6PC) and glucose-6-phosphate transporter (SLC37A4), respectively. The high rates of consanguineous marriages in ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2020, 15(1):35]

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Selective ß2-Adrenoceptor Agonists and Relevant Hyperlactatemia: Systematic Review and Meta-Analysis.

Alina G Liedtke, Sebastiano A G Lava, Gregorio P Milani, Carlo Agostoni, Viola Gilardi, Mario G Bianchetti, Giorgio Treglia, Pietro B Faré,

Selective ß2-agonists have been imputed as potential cause of l-hyperlactatemia since the 1970s. To document the prevalence of hyperlactatemia associated with selective ß2-agonists and to investigate the predisposing factors, we searched for published articles until April 2019 pertaining to the interplay of administration of selective ß2-agonists and circulating l-lactic acid ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 9(1):]

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Connecting two worlds: positive correlation between physicochemical approach with blood gases and pH in pediatric ICU setting.

Chanapai Chaiyakulsil, Papope Mueanpaopong, Rojjanee Lertbunrian, Somchai Chutipongtanate,

OBJECTIVE:Physicochemical approach such as strong ion difference provides a novel concept in understanding and managing acid-base disturbance in patients. However, its application in pediatrics is limited. This study aimed to evaluate a correlation between the physicochemical approach and blood gas pH for acid-base determination in critically ill pediatric patients. RESULTS:A ... Read more >>

BMC Res Notes (BMC research notes)
[2019, 12(1):742]

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Intraoperative Urine Output Is Associated with Postoperative Outcome in Pediatric Population Undergone Major Abdominal Operations.

Chao Zheng, Chunbao Guo,

Aim:Few data support the advantage of confirming a low urine output target during Roux-en-Y hepaticojejunostomy, which was widely used as an indication for fluid administration. We aimed at evaluating postoperative outcomes in terms of urine output in pediatric patients undergoing elective Roux-en-Y hepaticojejunostomy. Methods:We retrospectively reviewed 689 patients who had ... Read more >>

Ther Clin Risk Manag (Therapeutics and clinical risk management)
[2019, 15:1453-1460]

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Two cases of ketosis-prone diabetes mellitus in Korean adolescents.

Won Bin Hwang, Ji Hyun Kim, Sung Min Cho,

In recent years, reports of diabetes mellitus (DM) cases that do not fit the traditional classification system have increased in prevalence. While insulin deficiency appears as type 1 DM (T1DM), the new type also has the clinical features of type 2 DM (T2DM); as such, this new type of DM ... Read more >>

Ann Pediatr Endocrinol Metab (Annals of pediatric endocrinology & metabolism)
[2019, 24(4):257-261]

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ECMO for Neonatal Sepsis in 2019.

Warwick Wolf Butt, Roberto Chiletti,

Sepsis and septic shock in newborns causes mortality and morbidity depending on the organism and primary site. ECMO provides cardiorespiratory support to allow adequate organ perfusion during the time for antibiotics and source control surgery (if needed) to occur. ECMO mode and cannulation site vary depending on support required and ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:50]

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