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Pediatric Patent Foramen Ovale Atrial Septal Defects

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MHCA with SACP versus DHCA in Pediatric Aortic Arch Surgery: A Comparative Study.

Ling Xie, Yan Xu, Guijin Huang, Mao Ye, Xiao Hu, Shiyu Shu, Harness Lynn,

The safety and efficacy of selective antegrade cerebral perfusion (SACP) in children undergoing aortic arch surgery are unclear. In this retrospective analysis, we compared moderate hypothermic circulatory arrest (MHCA; n = 61) plus SACP vs deep hypothermic circulatory arrest (DHCA; n = 53) in children undergoing aortic arch surgery during a period from January ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):4439]

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Clinical exome sequencing revealed that FLNC variants contribute to the early diagnosis of cardiomyopathies in infant patients.

Feifan Xiao, Qiufen Wei, Bingbing Wu, Xu Liu, Aiyao Mading, Lin Yang, Yan Li, Fang Liu, Xinnian Pan, Huijun Wang,

Background:FLNC encodes actin-binding protein and is mainly concentrated in skeletal and cardiac muscle. Mutations in FLNC were found in cardiomyopathies. To date, studies on FLNC-cardiomyopathies have mainly been reported in adults. There are limited studies that have investigated FLNC variants in pediatric patients with cardiomyopathies. Methods:We summarized the patients who ... Read more >>

Transl Pediatr (Translational pediatrics)
[2020, 9(1):21-33]

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Cardiovascular Imaging for Guiding Interventional Therapy in Structural Heart Diseases.

Nora Rat, Iolanda Muntean, Diana Opincariu, Liliana Gozar, Rodica Togănel, Monica Chițu,

Development of interventional methods has revolutionized the treatment of structural cardiac diseases. Given the complexity of structural interventions and the anatomical variability of various structural defects, novel imaging techniques have been implemented in the current clinical practice for guiding the interventional procedure and for selection of the device to be ... Read more >>

Curr Med Imaging Rev (Current medical imaging reviews)
[2020, 16(2):111-122]

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[Physiological and paraphysiological echocardiographic findings in neonatal and pediatric age].

Maria Giovanna Russo, Annapaola Cirillo, Gabriele Rinelli, Ugo Vairo, Silvia Favilli, Antonella Moreo, Stefano Domenicucci, Michele Massimo Gulizia, Domenico Gabrielli,

Echocardiographic quantification is crucial for the diagnosis and management of patients with acquired and congenital heart disease (CHD). In neonatal and pediatric age, the echocardiogram begins with subxiphoid, or subcostal, imaging instead of left parasternal views. This allows for the determination of visceral situs (site or location) at the beginning ... Read more >>

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2019, 20(11):627-631]

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Torque device suture technique to achieve hemostasis in large-bore venous access.

Brian Karahalios, Stephanie F Rojas, Rahul Singh, Miguel C Cavazos, Ponraj Chinnadurai, C Huie Lin,

OBJECTIVES:To describe and compare a novel technique using a torque device to manage figure-of-eight suture tension for venous access hemostasis in patients who have undergone atrial septal defect (ASD) or patent foramen ovale (PFO) closure. BACKGROUND:Large bore venous access has become increasingly important in transcatheter procedures, but management of hemostasis ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2020, 95(4):722-725]

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Characteristics of Patent Ductus Arteriosus in Congenital Rubella Syndrome.

Michiko Toizumi, Cam Giang T Do, Hideki Motomura, Tin N Do, Hirofumi Fukunaga, Makiko Iijima, Nhan Nt Le, Hung Thanh Nguyen, Hiroyuki Moriuchi, Lay-Myint Yoshida,

This study investigated the characteristics of congenital rubella syndrome (CRS)-associated cardiac complications, particularly patent ductus arteriosus (PDA). We reviewed the medical records of patients with CRS who were admitted to the Children's Hospital 1 in Vietnam between December 2010 and December 2012, and patients with CRS who underwent PDA transcatheter ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):17105]

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The impact of trisomy 21 on epidemiology, management, and outcomes of congenital duodenal obstruction: a population-based study.

George S Bethell, Anna-May Long, Marian Knight, Nigel J Hall, ,

PURPOSE:Congenital duodenal obstruction (CDO) is associated with trisomy 21 (T21), or Down's syndrome, in around a third of infants. The aim of this study was to explore the impact of T21 on the epidemiology, management, and outcomes of infants with CDO. METHODS:Data were prospectively collected from specialist neonatal surgical centres ... Read more >>

Pediatr. Surg. Int. (Pediatric surgery international)
[2020, 36(4):477-483]

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Interventional catheterization in pediatric catheterization laboratories for congenital and structural heart defects during 2009-2018 in Poland. Report of the National Consultant of Pediatric Cardiology.

Jacek Białkowski, Małgorzata Szkutnik, Agnieszka Powałka,

Postepy Kardiol Interwencyjnej (Postepy w kardiologii interwencyjnej = Advances in interventional cardiology)
[2019, 15(3):374-376]

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Pathogenic copy number variants are detected in a subset of patients with gastrointestinal malformations.

Johanna Winberg, Peter Gustavsson, Ellika Sahlin, Magnus Larsson, Henrik Ehrén, Magdalena Fossum, Tomas Wester, Ann Nordgren, Agneta Nordenskjöld,

BACKGROUND:Gastrointestinal atresias and urological defects are main causes of pediatric surgery in infants. As copy number variants (CNVs) have been shown to be involved in the development of congenital malformations, the aim of our study was to investigate the presence of CNVs in patients with gastrointestinal and urological malformations as ... Read more >>

Mol Genet Genomic Med (Molecular genetics & genomic medicine)
[2020, 8(2):e1084]

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Two case reports of fetal alcohol syndrome: broadening into the spectrum of cardiac disease to personalize and to improve clinical assessment.

R Onesimo, C De Rose, A B Delogu, A Battista, C Leoni, S Veltri, G De Rosa, G Zampino,

BACKGROUND:Fetal alcohol spectrum disorder (FASD) refers to a broad spectrum of disabilities, in infants and children, resulting from moderate to excessive prenatal alcohol exposure. Significant associations with alcohol exposure were already reported with congenital structural heart defects: i.e. ventricular septal defects, atrial septal defects, conotruncal defects. CASES PRESENTATION:We describe two ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2019, 45(1):167]

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Impact of Persistent Left Superior Vena Cava Detection in a Normal Neonatal Population through Echocardiography.

Yen-Jun Chao, Ming-Ren Chen, Wei-Li Hung, Shu-Jen Yeh, Shan-Miao Lin,

Background:Persistent left superior vena cava (PLSVC) is a vascular anomaly that is usually asymptomatic and detected incidentally. The incidence of PLSVC has seldom been evaluated in normal populations. In this study, we determined the incidence of PLSVC in a normal neonatal population using transthoracic echocardiography. We also evaluated the associations ... Read more >>

Acta Cardiol Sin (Acta Cardiologica Sinica)
[2019, 35(6):600-604]

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Diagnostic accuracy of multi-slice computed tomography in children with Abernethy malformation.

Chen Guo, Yu-Min Zhong, Qian Wang, Li-Wei Hu, Xiao-Hong Gu, Hong Shao, Wei Wu, Jian-Feng Cao, Hai-Sheng Qiu,

BACKGROUND:Abernethy malformation is a rare congenital abnormality. Imaging examination is an important method for the diagnosis. The purpose of this study was to demonstrate manifestations of multi-slice computed tomography (MSCT) in Abernethy malformation and its diagnostic accuracy. METHODS:Fourteen children with Abernethy malformation were admitted to our center in China between ... Read more >>

BMC Med Imaging (BMC medical imaging)
[2019, 19(1):97]

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Respiratory syncytial virus acute respiratory infection-associated hospitalizations in preterm Mexican infants: A cohort study.

Daniela Benítez-Guerra, Cecilia Piña-Flores, Miguel Zamora-López, Francisco Escalante-Padrón, Victoria Lima-Rogel, Ana María González-Ortiz, Marcela Guevara-Tovar, Sofía Bernal-Silva, Beatriz Benito-Cruz, Fernanda Castillo-Martínez, Luz E Martínez-Rodríguez, Vianney Ramírez-Ojeda, Nallely Tello-Martínez, Rodrigo Lomelí-Valdez, Jack Salto-Quintana, Sandra Cadena-Mota, Daniel E Noyola,

BACKGROUND:Respiratory syncytial virus (RSV) is the leading cause of severe acute respiratory infections (ARI) in preterm infants. The incidence of RSV-associated hospitalizations has not been defined in Mexico. OBJECTIVES:To determine the incidence of ARI- and RSV-associated hospitalizations in preterm infants during the first year of life. METHODS:Prospective cohort study of ... Read more >>

Influenza Other Respir Viruses (Influenza and other respiratory viruses)
[2020, 14(2):182-188]

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Complete transposition of great arteries associated with total anomalous pulmonary venous connection: An unusual cause for early left ventricular myocardial mass regression.

Neeraj Aggarwal, Reena K Joshi, Nabil Paktin, Mridul Agarwal, Raja Joshi,

A 24-day-old apparently asymptomatic neonate was found to have complete transposition of great arteries with small patent ductus arteriosus and restrictive patent foramen ovale. The neonate was found to have relatively high saturations (saturations = 88%) despite inadequate mixing communications. Echo findings were suggestive of significant dilatation of right atrium ... Read more >>

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2019, 12(3):302-304]

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An atrial septal aneurysm with an organized thrombus in an asymptomatic patient: A case report.

Xinxin Wang, Chunguo Wang, Dehua Ma, Jiang Jin, Bo Zhang, Chengchu Zhu, Baofu Chen,

INTRODUCTION:An atrial septal aneurysm (ASA) is a rare congenital cardiac deformity characterized by interatrial septum protruding into atria forming a saccular structure. PATIENT CONCERNS:In our case, a 42-year-old female patient presented to our hospital complained of palpitation. DIAGNOSIS:Transthoracic echocardiography detected a 3.4 × 3.4 cm circular mass attached to the interatrial ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(48):e18074]

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The Early "Unnatural" History Following Surgical Repair of Ventricular Septal Defects.

Sathish M Chikkabyrappa, Justin T Tretter, Arpan R Doshi, Sujatha Buddhe, Puneet Bhatla, Achi Ludomirsky,

Introduction:Surgical outcomes for simple ventricular septal defects (VSD) have been excellent in the past three decades. For this project, the timing of resolution of left-sided dilation and mitral regurgitation (MR) following VSD repair was assessed. Methods:Echocardiographic data surrounding surgery of 42 consecutive children who underwent surgical patch repair of a ... Read more >>

Kans J Med (Kansas journal of medicine)
[2019, 12(4):121-124]

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Risk factors of meconium-related ileus in very low birth weight infants: patients-control study.

Jeik Byun, Ji-Won Han, Joong Kee Youn, Hee-Beom Yang, Seung Han Shin, Ee-Kyung Kim, Hyun-Young Kim, Sung-Eun Jung,

Very low birth weight (VLBW) neonates experience various problems, including meconium-related ileus (MRI). This study investigated the risk factors of MRI and surgical MRI in VLBW infants. VLBW neonates admitted to the Neonatal Intensive Care Unit of Seoul National University Children's Hospital from October 2002 to September 2016 were included ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):4674]

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Preoperative adrenal insufficiency in a neonate with congenital heart disease surgery.

Shankar Vithalrao Kadam, Kamlesh B Tailor, Vinay Hk Joshi, Suresh G Rao,

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2019, 12(3):351-353]

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Anomalous aortic origin of the pulmonary arteries: Case series and literature review.

Salvatore Agati, Carlos Guerra Sousa, Felice Davide Calvaruso, Rosanna Zanai, Ivana Campanella, Daniela Poli, Alfredo Di Pino, Luca Borro, Fiore Salvatore Iorio, Massimiliano Raponi, Robert H Anderson, Simone Reali, Andrea De Zorzi, Aurelio Secinaro,

Anomalous origin of the pulmonary arteries from the ascending aorta is a rare, but severe clinical entity necessitating a scrupulous evaluation. Either the right or the left pulmonary arteries can arise directly from the ascending aorta while the other pulmonary artery retains its origin from the right ventricular outflow tract. ... Read more >>

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2019, 12(3):248-253]

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Recurrent arterial ischemic strokes in a patient with patent foramen ovale and ductus arteriosus: Presentation of our management and review of the literature.

Dimitrios Panagopoulos, Sofia Loukopoulou, Evangelos Karanasios, Nikolaos Eleftherakis,

Ischemic stroke in children is a relatively rare entity, relative to the adult population. The most common potential risk factors include cardiac embolism, prothrombotic states and vasculopathies. The diagnosis is concerning for the need to identify the underlying cause. Treatment of the proximate source of ischemia can often protect against ... Read more >>

Glob Cardiol Sci Pract (Global cardiology science & practice)
[2019, 2019(2):e201913]

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Hemodynamic and clinical effects of selexipag in children with pulmonary hypertension.

Abraham Rothman, Gabriel Cruz, William N Evans, Humberto Restrepo,

Selexipag is an oral prostacyclin receptor agonist; it was recently approved for use in adults with pulmonary arterial hypertension. The safety and efficacy of selexipag has not yet been determined in the pediatric population. We describe short-term hemodynamic and clinical data with selexipag therapy in four pediatric patients with pulmonary ... Read more >>

Pulm Circ (Pulmonary circulation)
[2020, 10(1):2045894019876545]

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Electrocardiography findings and clinical presentation in Ebstein's anomaly.

Mayank Dalakoti, Devinder Singh, Wee Tiong Yeo, Lik Wui Edgar Tay, Kian Keong Poh,

Ebstein's anomaly is a congenital malformation characterised by tricuspid valve pathology with right heart enlargement. Cases of Ebstein's anomaly can vary widely in severity, anatomy and presentation. In this article, we presented three cases of Ebstein's anomaly and discussed the presentation as well as electrocardiographic (ECG) changes. Patients may first ... Read more >>

Singapore Med J (Singapore medical journal)
[2019, 60(11):560-564]

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Diagnosis and surgical repair of congenital double aortic arch in infants.

Yiting Yang, Xin Jin, Zhengxia Pan, Yonggang Li, Chun Wu,

OBJECTIVES:Double aortic arch (DAA) is a rare congenital vascular malformation. This study aims to summarize the experience of diagnosis and surgical treatment for congenital double aortic arch. METHODS:The clinical data of 24 cases with double aortic arch (DAA) from January 2008 to January 2018 in our hospital was reviewed retrospectively. ... Read more >>

J Cardiothorac Surg (Journal of cardiothoracic surgery)
[2019, 14(1):160]

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Feasibility and performance of catheter ablation with zero-fluoroscopy approach for regular supraventricular tachycardia in patients with structural and/or congenital heart disease.

Aleksandra Morka, Janusz Śledź, Karol Deutsch, Bartosz Ludwik, Magdalena Zagrodzka, Lesław Szydłowski, Sebastian Stec,

Patients with structural heart disease (SHD) are more difficult to ablate than those with a structurally healthy heart. The reason may be technical problems. We compared periprocedural data in unselected patients (including SHD group) recruited for zero-fluoroscopy catheter ablation (ZF-CA) of supraventricular arrhythmias (SVTs).Consecutive adult patients with atrioventricular nodal reentry ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(41):e17333]

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Initial experiences with a novel biodegradable device for percutaneous closure of atrial septal defects: From preclinical study to first-in-human experience.

Yi-Fan Li, Yu-Mei Xie, Jun Chen, Bo-Ning Li, Zhao-Feng Xie, Shu-Shui Wang, Zhi-Wei Zhang,

OBJECTIVE:To evaluate the feasibility, safety, and effectiveness of a novel, absorbable atrial septal defect (ASD) closure device made of poly-l-lactic acid (PLLA) in a swine model of ASD and for the first time in humans. METHODS:A preclinical safety study was conducted using a swine model of ASD. In a clinical ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2020, 95(2):282-293]

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