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Pediatric Mitral Valve Insufficiency

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Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Different Generations of Amplatzer Devices: Multicenter Experience.

Roberto Mijangos-Vázquez, Amal El-Sisi, Juan P Sandoval Jones, José A García-Montes, Rogelio Hernández-Reyes, Rodina Sobhy, Antoine Abdelmassih, Mohammed M Soliman, Safaa Ali, Tatiana Molina-Sánchez, Carlos Zabal,

Objectives:To demonstrate safety and efficacy of using different generations of softer Amplatzer™ devices for ventricular septal defect (VSD) closure to avoid serious complications at follow-up. Background:Transcatheter closure of perimembranous ventricular septal defects (PmVSD) is a well-established procedure; however, it is associated with unacceptable incidence of complete heart block. Great advantages ... Read more >>

J Interv Cardiol (Journal of Interventional Cardiology)
[2020, 2020:8948249]

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Implantation of the Berlin Heart EXCOR ventricular assist device.

Erhan Urganci, Thomas Aschacher, Franziska Wittmann, Stephan Hornykewycz, Claudia Herbst, Sigrid Sandner, Günther Laufer, Daniel Zimpfer,

The Berlin Heart EXCOR® is a mechanical, pulsatile ventricular assist device. The paracorporeal assist device is pneumatically driven and can be used for long-term bridging therapy of one or both ventricles (LVAD, BIVAD, RVAD). It is specifically designed for pediatric patients and can be used in neonates as well as ... Read more >>

Multimed Man Cardiothorac Surg (Multimedia manual of cardiothoracic surgery : MMCTS)
[2020, 2020:]

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Cardiac Valvular Lesions due to Kawasaki Disease: A Japanese Nationwide Survey.

Etsuko Tsuda, Mayumi Yashiro, Yosikazu Nakamura,

OBJECTIVES:To clarify the characteristics of valvular lesions after Kawasaki disease with a Japanese nationwide survey. STUDY DESIGN:Among 137 026 patients in the nationwide Japanese surveys between 2007 and 2016, 290 (0.2%) with valvular sequelae were investigated by questionnaires. RESULTS:Among the 290 patients with valvular sequelae, mitral regurgitation (MR), tricuspid regurgitation, aortic ... Read more >>

J. Pediatr. (The Journal of pediatrics)
[2020, 218:78-84.e2]

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Mitral Valve Surgery in Neonates, Infants, and Children: Surgical Approach, Outcomes, and Predictors.

Erin Isaacson, Camille Lucjak, William K Johnson, Ziyan Yin, Tao Wang, Lisa Rein, Ronald K Woods, James S Tweddell, Viktor Hraska, Michael E Mitchell,

The surgical treatment of mitral disease in pediatrics is challenging. Managing diversity in patient anatomy, growth, and the need for long-term anticoagulation requires trade-offs between imperfect solutions. We sought to assess our approach to pediatric mitral valve surgery and identify predictors associated with mortality and recurrent mitral disease. The medical ... Read more >>

Semin. Thorac. Cardiovasc. Surg. (Seminars in thoracic and cardiovascular surgery)
[2020, :]

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Anomalous origin of the left coronary artery from the pulmonary artery: A surgical certainty.

Ayesha Butt, Muhammad Muneer Amanullah, Mehnaz Atiq Amanullah, Asif Hasan, Waris Ahmad,

This study aims to assess the clinical presentation and the outcomes of a surgical correction of an anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA). A retrospective review was carried out on the charts of six patients admitted for ALCAPA surgery at Aga Khan University Hospital, ... Read more >>

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2020, 70(3):561-564]

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Clinical exome sequencing revealed that FLNC variants contribute to the early diagnosis of cardiomyopathies in infant patients.

Feifan Xiao, Qiufen Wei, Bingbing Wu, Xu Liu, Aiyao Mading, Lin Yang, Yan Li, Fang Liu, Xinnian Pan, Huijun Wang,

Background:FLNC encodes actin-binding protein and is mainly concentrated in skeletal and cardiac muscle. Mutations in FLNC were found in cardiomyopathies. To date, studies on FLNC-cardiomyopathies have mainly been reported in adults. There are limited studies that have investigated FLNC variants in pediatric patients with cardiomyopathies. Methods:We summarized the patients who ... Read more >>

Transl Pediatr (Translational pediatrics)
[2020, 9(1):21-33]

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Ventricular Tachycardia in an Infant Without Congenital Anomaly: A Case Report.

Nouhad El Joueid, Marianne Touma Boulos, Simon Abou Jaoude, Linda Daou,

Ventricular tachycardia (VT) is a serious form of arrhythmia that can be life-threatening; that's why diagnosis and treatment are very important in order to avoid serious complications. We are reporting this case of VT which is a rare entity, especially, in healthy infants. This infant, without cardiac pathology known from ... Read more >>

Cardiol Res (Cardiology research)
[2020, 11(1):61-65]

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Infectious pseudo-aneurysm of the left ventricle: a case report and a review of the literature.

Amadu E. Juliana, Kevin H. van ’t Kruys, Pieter G. Voigt, Nico A. Blom,

BackgroundIn the workup of a pediatric patient with pericarditis we found evidence of a pseudo-aneurysm of the left ventricle, which is a rare complication of purulent pericarditis.Case presentationWe present a case of a six-year-old girl who was diagnosed with pericarditis and a fistula between the pericardial and the intra-luminal space ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20:]

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Echocardiographic examination of mitral valve abnormalities in the paediatric population: current practices.

Massimiliano Cantinotti, Raffaele Giordano, Martin Koestenberger, Inga Voges, Giuseppe Santoro, Eliana Franchi, Nadia Assanta, Israel Valverde, John Simpson, Shelby Kutty,

We reviewed the recent literature for echocardiographic assessment of mitral valve abnormalities in children. A literature search was performed within the National Library of Medicine using the keywords "mitral regurgitation and/or stenosis, children." The search was refined by adding the keywords "echocardiographic definition, classification, and evaluation." Thirty-one studies were finally ... Read more >>

Cardiol Young (Cardiology in the young)
[2020, 30(1):1-11]

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A Case Report of a Japanese Boy with Morquio A Syndrome: Effects of Enzyme Replacement Therapy Initiated at the Age of 24 Months.

Akari Nakamura-Utsunomiya, Toshio Nakamae, Reiko Kagawa, Shuhei Karakawa, Sonoko Sakata, Fumiaki Sakura, Chihiro Tani, Yoshiko Matsubara, Takashi Ishino, Go Tajima, Satoshi Okada,

BACKGROUND:Morquio A syndrome, mucopolysaccharidosis type IVA (MPS IVA), is a lysosomal storage disorder caused by the deficient activity of N-acetylgalactosamine-6-sulfatase (GalNac6S), due to alterations in the GALNS gene. This disorder results in marked abnormalities in bones and connective tissues, and affects multiple organs. Here, we describe the clinical course of ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(3):]

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Cardiac Evaluation using Two-Dimensional Speckle-Tracking Echocardiography and Conventional Echocardiography in Taiwanese Patients with Mucopolysaccharidoses.

Hsiang-Yu Lin, Chih-Kuang Chuang, Chung-Lin Lee, Ming-Ren Chen, Kuo-Tzu Sung, Shan-Miao Lin, Charles Jia-Yin Hou, Dau-Ming Niu, Tung-Ming Chang, Chung-Lieh Hung, Shuan-Pei Lin,

BACKGROUND:Mucopolysaccharidoses (MPSs) are a group of rare inherited metabolic disorders that can damage various organs, including the heart. Cardiac abnormalities have been observed in patients with all MPS types, with the most documented abnormalities being cardiac valvular regurgitation and stenosis, valvular thickening, and hypertrophic cardiomyopathy. METHODS:Cardiac features of 53 Taiwanese ... Read more >>

Diagnostics (Basel) (Diagnostics (Basel, Switzerland))
[2020, 10(2):]

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Tricuspid valve infective endocarditis associated with aseptic meningitis: a rare presentation in a child.

Gülsüm Alkan, Melike Emiroğlu, Ahmet Sert, Ayşe Kartal, Mehmet Öc,

Infective endocarditis (IE) is a rare but a potentially life-threatening infectious disease. Atypical presentations cause delays in the diagnosis. Neurological involvement such as meningitis or meningismus, are especially common in mitral valve endocarditis, but unusual in tricuspid valve endocarditis. Although few cases of right-sided IE have been reported with neurological ... Read more >>

Arch Argent Pediatr (Archivos argentinos de pediatria)
[2020, 118(1):e22-e25]

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Late Presentation of a Congenitally Corrected Transposition of Great Arteries and Hemodynamically Balanced Ventricles Associated with a Large Ventricular Septal Defect and Severe Pulmonary Stenosis: A Case Report and a Multi-Imaging Approach.

Khaled Elenizi, Rasha Alharthi, Anthony Matta, Abdulrahman Aljuayli, Michel Galinier,

BACKGROUND Congenitally corrected transposition of great arteries (ccTGA) represents a distinct rare group of congenital heart diseases. Survival of unoperated ccTGA in the presence of large ventricular septal defect (VSD) is exceptional. Furthermore, late presentation of such patients in the absence of severe pulmonary hypertension or severe systemic right ventricle ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e920822]

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Periodontitis and cardiovascular diseases: Consensus report.

Mariano Sanz, Alvaro Marco Del Castillo, Søren Jepsen, Jose R Gonzalez-Juanatey, Francesco D'Aiuto, Philippe Bouchard, Iain Chapple, Thomas Dietrich, Israel Gotsman, Filippo Graziani, David Herrera, Bruno Loos, Phoebus Madianos, Jean-Baptiste Michel, Pablo Perel, Burkert Pieske, Lior Shapira, Michael Shechter, Maurizio Tonetti, Charalambos Vlachopoulos, Gernot Wimmer,

BACKGROUND:In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non-communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of ... Read more >>

J. Clin. Periodontol. (Journal of clinical periodontology)
[2020, 47(3):268-288]

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Changes in valvular regurgitation in mid-term follow-up of children with first attack acute rheumatic fever: first evaluation after the updated Jones criteria.

Muhlike Güler, Fuat Laloğlu, Naci Ceviz,

AIM:In present study, we aimed to evaluate the changes in valvular regurgitations in mid-term follow-up of children with first attack acute rheumatic fever diagnosed after updated Jones criteria. MATERIALS AND METHODS:The medical records of the children diagnosed with acute rheumatic fever between June 2015 and November 2018 were evaluated retrospectively. ... Read more >>

Cardiol Young (Cardiology in the young)
[2020, 30(3):369-371]

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Streptococcus pyogenes Endocarditis Associated With Varicella-Case Report and Review of the Literature.

Patrizia Savoia, Ulrich Heininger, Michael Buettcher,

Infection with varicella zoster virus (VZV) is usually a benign and self-limiting disease. Serious complications by bacterial pathogens do occur, such as necrotising fasciitis (NF). One of the most important is Streptococcus pyogenes (or Group A Streptococcus, GAS), which colonizes epithelial surfaces, primarily of the throat and skin. In rare ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:500]

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Lyme Endocarditis as an Emerging Infectious Disease: A Review of the Literature.

Aleksandra Nikolić, Darko Boljević, Milovan Bojić, Stefan Veljković, Dragana Vuković, Bianca Paglietti, Jelena Micić, Salvatore Rubino,

Lyme endocarditis is extremely rare manifestation of Lyme disease. The clinical manifestations of Lyme endocarditis are non-specific and can be very challenging diagnosis to make when it is the only manifestation of the disease. Until now, only a few cases where reported. Physicians should keep in mind the possibility of ... Read more >>

Front Microbiol (Frontiers in Microbiology)
[2020, 11:278]

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Clinical characteristics of pediatric patients with first-attack acute rheumatic fever following the updated guideline.

Mühlike Güler, Fuat Laloğlu, Haşim Olgun, Naci Ceviz,

Aim:To evaluate the clinical features of children diagnosed as having acute rheumatic fever between June 2015 and November 2018, and the changes observed in patient groups in comparison with data obtained in previous years. The diagnosis of acute rheumatic fever was made using the updated Jones criteria. Material and Methods:The ... Read more >>

Turk Pediatri Ars (Turk pediatri arsivi)
[2019, 54(4):220-224]

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Abnormally increased carotid intima media-thickness and elasticity in patients with Morquio A disease.

Raymond Y Wang, Kyle D Rudser, Donald R Dengel, Nicholas Evanoff, Julia Steinberger, Nina Movsesyan, Robert Garrett, Katherine Christensen, Deborah Boylan, Stephen R Braddock, Marwan Shinawi, Qi Gan, Adriana M Montaño,

BACKGROUND:Cardiovascular disease frequently causes morbidity and mortality in mucopolysaccharidoses (MPS); however, cardiovascular anatomy and dysfunction in MPS IVA (Morquio A disease) is not well described. Consequently, the study aimed to compare carotid artery structure and elasticity of MPS IVA patients with other MPS patients and healthy control subjects, and quantitate ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2020, 15(1):73]

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Use of Sodium Bicarbonate During Pediatric Cardiac Admissions with Cardiac Arrest: Who Gets It and What Does It Do?

Rohit S Loomba, Mubbasheer Ahmed, Mubeena Abdulkarim, Enrique G Villarreal, Saul Flores,

The objectives of this study were to characterize the use of sodium bicarbonate in pediatric cardiac admissions that experience cardiac arrest, to determine sodium bicarbonate use over the years, and to determine the impact of sodium bicarbonate on length of admissions, billed charges, and inpatient mortality. A cross-sectional study was ... Read more >>

Children (Basel) (Children (Basel, Switzerland))
[2019, 6(12):]

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Prenatal Diagnosis of Aorto-Left Ventricular Tunnel With Dysplastic Bicuspid Aortic Valve: From Fetal Cardiac Failure to Favorable Outcome.

Ba Luu Truong, Anne Moreau De Bellaing, Emmanuelle Vialle, Ayman Haydar, Pascal Vouhe, Pierre Simon Jouk, Gerard Blaysat,

Aorto-left ventricular tunnel (ALVT) is a rare congenital heart defect. Surgery has to be performed early to avoid life-threatening complications. Prenatal diagnosis of this defect is challenging. We report a case of ALVT diagnosed in a fetus showing premature severe cardiac failure at 24 GA. The new born was operated ... Read more >>

Front Pediatr (Frontiers in Pediatrics)
[2020, 8:69]

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Takayasu arteritis in a rural hospital in Indonesia.

Michael Lusida, Mohammad Zakky Kurniawan, Johanes Nugroho,

Takayasu arteritis (TA) is a rare chronic granulomatous inflammation of the aorta or its branches and is prevalent all around the world. It causes stenosis of large arteries and ischaemic damage to target organs. There is usually a delay in recognising TA because of the rarity and unfamiliarity with the ... Read more >>

BMJ Case Rep (BMJ case reports)
[2020, 13(1):]

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Posterior mitral leaflet extension using autologous pericardium to repair a hammock mitral valve associated with severe mitral valve regurgitation in a 4-month-old boy.

Toshi Maeda, Keiichi Fujiwara, Kosuke Yoshizawa, Haruko Ishihara, Hisanori Sakazaki,

We successfully repaired a hammock mitral valve associated with severe mitral valve regurgitation in a 4-month-old boy using posterior leaflet extension along with glutaraldehyde-treated autologous pericardium and the splitting of bilateral papillary muscles. Surgical reinterventions were performed for the bilateral papillary muscles at 14 and 24 months postoperatively. The extended autologous ... Read more >>

Gen Thorac Cardiovasc Surg (General thoracic and cardiovascular surgery)
[2019, :]

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Rare accessory pathway between a giant left atrial appendage and the left ventricle.

Misugi Emi, Hisaaki Aoki, Yoshihide Nakamura, Yasuhiro Hirano, Kunihiko Takahashi, Futoshi Kayatani,

HeartRhythm Case Rep (HeartRhythm case reports)
[2020, 6(3):131-134]

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Myhre Syndrome Associated With Dunbar Syndrome and Urinary Tract Abnormalities: A Case Report.

Zofia Varenyiova, Gabriela Hrckova, Denisa Ilencikova, Ludmila Podracka,

Myhre syndrome is a rare condition caused by a mutation in the SMAD4 gene, which leads to a defective TGF-β/BMP signaling, resulting in the proliferation of abnormal fibrous tissues. Clinically, patients with Myhre syndrome manifest with defects of connective tissue (skin, muscles, joints), and cardiovascular and neurological impairment. In our ... Read more >>

Front Pediatr (Frontiers in Pediatrics)
[2020, 8:72]

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