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Pediatric Hypertension

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Adult outcomes of childhood bronchiectasis.

Dawn Sibanda, Rosalyn Singleton, John Clark, Christine Desnoyers, Ellen Hodges, Gretchen Day, Gregory Redding,

Recent literature has highlighted the importance of transition from paediatric to adult care for children with chronic conditions. Non-cystic fibrosis bronchiectasis is an important cause of respiratory morbidity in low-income countries and in indigenous children from affluent countries; however, there is little information about adult outcomes of childhood bronchiectasis. We ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2020, 79(1):1731059]

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Sleep Disturbance in Pediatric Intracranial Hypertension.

Alexandra B Kornbluh, Katherine Thompson, Gada Mcmahen, David L Rogers, Catherine O Jordan, Shawn C Aylward, Lenora M Lehwald,

STUDY OBJECTIVES:There is a well-established association between headache disorders and sleep disturbances in children, but it is unknown if sleep disturbance plays a role in pediatric intracranial hypertension. The objective of this study was to examine sleep issues related to pediatric intracranial hypertension. METHODS:Patients with intracranial hypertension who were followed ... Read more >>

J Clin Sleep Med (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine)
[2020, :]

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Sleep Disturbance in Pediatric Intracranial Hypertension.

Alexandra B Kornbluh, Katherine Thompson, Gada Mcmahen, David L Rogers, Catherine O Jordan, Shawn C Aylward, Lenora M Lehwald,

STUDY OBJECTIVES:There is a well-established association between headache disorders and sleep disturbances in children, but it is unknown if sleep disturbance plays a role in pediatric intracranial hypertension. The objective of this study was to examine sleep issues related to pediatric intracranial hypertension. METHODS:Patients with intracranial hypertension who were followed ... Read more >>

J Clin Sleep Med (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine)
[2020, :]

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Drug Treatment of Pulmonary Hypertension in Children.

Catherine M Avitabile, Erika E Vorhies, David Dunbar Ivy,

Pulmonary arterial hypertension (PAH) is a rare disease in infants and children that is associated with significant morbidity and mortality. The disease is characterized by progressive pulmonary vascular functional and structural changes resulting in increased pulmonary vascular resistance and eventual right heart failure and death. In many pediatric patients, PAH ... Read more >>

Paediatr Drugs (Paediatric drugs)
[2020, 22(2):123-147]

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Use of treprostinil in pediatric pulmonary hypertension: case reports and review of the literature.

Arthur Gavotto, Fanny Thomas, Oscar Werner, Johan Moreau, Pascal Amedro,

BACKGROUND:Add-on therapy with prostacyclin in pediatric refractory pulmonary hypertension poses a challenge, especially when considering continuous intravenous administration in younger children. A search for alternate routes of drug delivery has led to the clinical investigation of stable and long-acting prostacyclin analogues, such as subcutaneous treprostinil. We reported two pediatric cases ... Read more >>

J. Cardiovasc. Pharmacol. (Journal of cardiovascular pharmacology)
[2020, :]

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Spleen stiffness measurement as a non-invasive test to evaluate and monitor portal hypertension in children with extrahepatic portal vein obstruction.

R Z Yuldashev, M M Aliev, Sh I Shokhaydarov, D B Tursunova,

PURPOSE:The aim of the study was to test the feasibility of spleen stiffness measurement (SSM) by two-dimensional shear wave elastography (2D-SWE) and compare data on its diagnostic use with upper gastrointestinal endoscopy in children with extrahepatic portal hypertension (EHPH) before and after surgery. METHODS:A total of 44 children were included ... Read more >>

Pediatr. Surg. Int. (Pediatric surgery international)
[2020, :]

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Reply to "Ultrasound evaluation of optic nerve sheath diameter to assess treatment efficacy in pediatric idiopathic intracranial hypertension".

Leman Tekin Orgun, Hatice Tuba Atalay, Ebru Arhan, Kursad Aydın, Ayşe Serdaroğlu,

Childs Nerv Syst (Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery)
[2020, :]

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Born with a solitary kidney: at risk of hypertension.

Claudio La Scola, Giuseppina Marra, Anita Ammenti, Andrea Pasini, Francesca Taroni, Cristina Bertulli, William Morello, Martina Ceccoli, Francesca Mencarelli, Stefano Guarino, Giuseppe Puccio, Giovanni Montini,

BACKGROUND:Subjects with a congenital solitary kidney (CSK) are believed to be at risk of hypertension due to their low number of nephrons. However, as CSK is a congenital abnormality of the kidney or urinary tract (CAKUT), subtle dysplastic changes contributing to hypertension cannot be excluded. METHODS:We retrospectively compared office blood ... Read more >>

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2020, :]

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Pediatric Liddle Syndrome Caused by a Novel SCNN1G Variant in a Chinese Family and Characterized by Early-onset Hypertension.

Peng Fan, Xiao-Cheng Pan, Di Zhang, Kun-Qi Yang, Ying Zhang, Tao Tian, Fang Luo, Wen-Jun Ma, Ya-Xin Liu, Lin-Ping Wang, Hui-Min Zhang, Lei Song, Jun Cai, Xian-Liang Zhou,

BACKGROUND:Liddle syndrome (LS), an autosomal dominant disorder, is a common monogenic hypertension in pediatrics. In this study, we reported a novel SCNN1G variant in a Chinese family with pediatric LS, and conduct a systematic review of ENaC-gene-positive LS cases to conclude the clinical genetic features of LS in childhood. METHODS:Next-generation ... Read more >>

Am. J. Hypertens. (American journal of hypertension)
[2020, :]

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Implantable LENUS pro pump for treprostinil infusion in three pediatric patients.

Maria Álvarez-Fuente, Elvira Garrido-Lestache, Natalia Rivero, Tomasa Centella, Maria J Lamas, Cesar Pérez-Caballero, Jose L Vázquez, Maria J Del Cerro,

BACKGROUND:Prostanoid treatment in patients with severe pulmonary arterial hypertension (PAH) has been proven safe and effective. Subcutaneous administration of treprostinil has side effects, which limits their use and acceptance. An implantable pump for continuous intravenous treprostinil infusion has been recently approved. We describe our experience with the implantable pump in ... Read more >>

Pediatr. Pulmonol. (Pediatric pulmonology)
[2020, :]

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Decompressive craniectomy in pediatric non-traumatic intracranial hypertension: a single center experience.

Vijai Williams, Arun Bansal, Muralidharan Jayashree, Javed Ismail, Ashish Aggarwal, S K Gupta, Sunit Singhi, Pratibha Singhi, Arun Kumar Baranwal, Karthi Nallasamy,

Purpose: To study the clinical profile and predictors of outcome in children undergoing decompressive craniectomy (DC) for non-traumatic intracranial hypertension (ICH).Materials and methods: Mixed observational study of children, aged 1 month-12 years, who underwent DC for non-traumatic ICH in a tertiary care pediatric intensive care unit from 2012 to 2017. ... Read more >>

Br J Neurosurg (British journal of neurosurgery)
[2020, :1-6]

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Abdominal compartment syndrome and decompressive laparotomy in children: a 9-year single-center experience.

Anthony di Natale, Ueli Moehrlen, Hannah Rachel Neeser, Noëmi Zweifel, Martin Meuli, Andrea Alexis Mauracher, Barbara Brotschi, Sasha Job Tharakan,

PURPOSE:Abdominal compartment syndrome (ACS) in children results in 100% mortality if left untreated. Decompressive laparotomy (DL) is the only effective treatment if conservative medical therapies have failed. This study aims to determine the incidence of ACS among pediatric patients who underwent an emergency laparotomy (EL), to describe the effect of ... Read more >>

Pediatr. Surg. Int. (Pediatric Surgery International)
[2020, 36(4):513-521]

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Prognostic Value of Ambulatory Blood Pressure Load in Pediatric CKD.

Jason Lee, Charles E McCulloch, Joseph T Flynn, Joshua Samuels, Bradley A Warady, Susan L Furth, Divya Seth, Barbara A Grimes, Mark M Mitsnefes, Elaine Ku,

BACKGROUND AND OBJECTIVES:Elevated BP load is part of the criteria for ambulatory hypertension in pediatric but not adult guidelines. Our objectives were to determine the prevalence of isolated BP load elevation and associated risk with adverse outcomes in children with CKD, and to ascertain whether BP load offers risk discrimination ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2020, :]

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How to Apply European and American Guidelines on High Blood Pressure in Children and Adolescents. A Position Paper Endorsed by the Italian Society of Hypertension and the Italian Society of Pediatrics.

Simonetta Genovesi, Gianfranco Parati, Marco Giussani, Gianni Bona, Cristiano Fava, Claudio Maffeis, Claudio Ferri, Ugo Giordano,

Children are defined as hypertensive when their blood pressure values equal or exceed the 95th percentile of the blood pressure value distribution in a pediatric population, according to gender, age and height. The population on which reference tables are based is of fundamental importance to establish the threshold values for ... Read more >>

High Blood Press Cardiovasc Prev (High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension)
[2020, :]

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Somatic regional oxygen saturation as an early marker of intra-abdominal hypertension in critically ill children:a pilot study.

Özden Özgür Horoz, Nagehan Aslan, Dinçer Yildizdaş, Yasemin Çoban, Yaşar Sertdemir, Awni Al-Subu,

BACKGROUND AND AIM:Intra-abdominal hypertension is a common clinical condition with high mortality and morbidity in pediatric intensive care units. The aim of this study was to test the feasibility of regional tissue oxygenation (rSO2) measurement using near-infrared spectroscopy and to assess the correlation between rSO2 and perfusion markers of intra-abdominal ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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A Systematic Review to Assess the Effectiveness of Technology-Based Interventions to Address Obesity in Children

Jayne Woodside, Megan McMullan, Rachel Millar,

<title>Abstract</title> <p> Background Childhood obesity is associated with a multitude of co-morbidities, including hypertension, hyperlipidaemia, cardiovascular disease and type 2 diabetes. Childhood obesity can also affect a young person’s social, emotional and mental health if they encounter negative prejudice and social marginalisation. Given the prevalence of overweight and ... Read more >>

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Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure.

John T Berger, Aline B Maddux, Ron W Reeder, Russell Banks, Peter M Mourani, Robert A Berg, Joseph A Carcillo, Todd Carpenter, Mark W Hall, Kathleen L Meert, Patrick S McQuillen, Murray M Pollack, Anil Sapru, Andrew R Yates, Daniel A Notterman, Richard Holubkov, J Michael Dean, David L Wessel, ,

OBJECTIVES:To characterize contemporary use of inhaled nitric oxide in pediatric acute respiratory failure and to assess relationships between clinical variables and outcomes. We sought to study the relationship of inhaled nitric oxide response to patient characteristics including right ventricular dysfunction and clinician responsiveness to improved oxygenation. We hypothesize that prompt ... Read more >>

Pediatr Crit Care Med (Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies)
[2020, :]

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Acute kidney injury in critically ill children and 5-year hypertension.

Erin Hessey, Sylvie Perreault, Louise Roy, Marc Dorais, Susan Samuel, Véronique Phan, Jean-Philippe Lafrance, Michael Zappitelli,

BACKGROUND:To develop a pediatric-specific hypertension algorithm using administrative data and use it to evaluate the association between acute kidney injury (AKI) in the intensive care unit (ICU) and hypertension diagnosis 5 years post-discharge. METHODS:Two-center retrospective cohort study of children (≤ 18 years old) admitted to the pediatric ICU in Montreal, Canada, between 2003 ... Read more >>

Pediatr. Nephrol. (Pediatric nephrology (Berlin, Germany))
[2020, :]

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Pediatric heart-lung transplantation: A contemporary analysis of outcomes.

Kyle W Riggs, Jacquelyn L Chapman, Marc Schecter, Christopher Towe, Farhan Zafar, David L S Morales,

BACKGROUND:Pediatric heart-lung transplantation (HLT) is rare, and no report has analyzed patient outcomes since time of listing. We analyzed pediatric HLTs to understand risk factors for waitlist and post-HLT mortality. METHODS:All pediatric (<18 year old) HLT candidates were identified within the UNOS database (n = 573) and grouped by age, era, and by ... Read more >>

Pediatr Transplant (Pediatric transplantation)
[2020, :e13682]

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Metabolic syndrome, clustering of cardiovascular risk factors and high carotid intima-media thickness in children and adolescents.

Min Zhao, Carmelo A Caserta, Carla C M Medeiros, Abel López-Bermejo, Anastasios Kollias, Qian Zhang, Lucia Pacifico, Thomas Reinehr, Mieczysław Litwin, Judit Bassols, Elisabetta L Romeo, Thacira D A Ramos, George S Stergiou, Lili Yang, Silvia Xargay-Torrent, Angela Amante, Tatianne M Estrela, Evangelos Grammatikos, Yuanyuan Zhang, Anna Prats-Puig, Danielle Franklin de Carvalho, Liu Yang, Gemma Carreras-Badosa, Mônica de Oliveira Simões, Yaping Hou, Esther Lizarraga-Mollinedo, Wang Shui, Teng Guo, Mingming Wang, Yanqing Zhang, Pascal Bovet, Bo Xi, ,

OBJECTIVE:The clinical utility of screening for pediatric metabolic syndrome (MetS) in children and adolescents is still controversial. We examined the performance of pediatric MetS vs. clustering of cardiovascular risk factors (which are the components of MetS) for predicting high carotid intima-media thickness (cIMT) in children and adolescents. METHODS:Participants included 2427 ... Read more >>

J. Hypertens. (Journal of hypertension)
[2020, 38(4):618-624]

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Report on the Epidemiological Features of Coronavirus Disease 2019 (COVID-19) Outbreak in the Republic of Korea from January 19 to March 2, 2020.

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Since the first case of coronavirus disease19 (COVID-19) was reported in Wuhan, China, as of March 2, 2020, the total number of confirmed cases of COVID-19 was 89,069 cases in 67 countries and regions. As of 0 am, March 2, 2020, the Republic of Korea had the second-largest number of ... Read more >>

J. Korean Med. Sci. (Journal of Korean medical science)
[2020, 35(10):e112]

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Serial Measurements of N-Terminal Pro-B-Type Natriuretic Peptide Serum Level for Monitoring Pulmonary Arterial Hypertension in Children.

Fatema Said, Meindina G Haarman, Marcus T R Roofthooft, Hans L Hillege, Mark-Jan Ploegstra, Rolf M F Berger,

OBJECTIVE:To assess the association between serially measured N-terminal pro-B-type natriuretic peptide (NT-proBNP) serum levels and disease severity in children with pulmonary arterial hypertension (PAH), and to assess its predictive value for death or (heart-)lung transplantation. STUDY DESIGN:This was a longitudinal cohort study of the Dutch National Network for Pediatric Pulmonary ... Read more >>

J. Pediatr. (The Journal of pediatrics)
[2020, :]

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Prevalence of Renal Dysfunction Among Pediatric Liver Transplant Recipients.

Mitra Basiratnia, Seyed Mohsen Dehghani, Fatemeh Razmjoee, Dorna Derakhshan,

INTRODUCTION:Renal dysfunction is among the common and considerable complications after liver transplantation and is principally attributable to immunosuppressive medications .The purpose of this study was to define the prevalence of hypertension and renal dysfunction among pediatric liver transplant recipients. METHODS:46 pediatric liver transplant recipients were assessed for hypertension utilizing ambulatory ... Read more >>

Iran J Kidney Dis (Iranian journal of kidney diseases)
[2020, 14(2):119-125]

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Current Issues in Bariatric Surgery for Adolescents with Severe Obesity: Durability, Complications, and Timing of Intervention.

Soo Min Ahn,

Conventional nonsurgical management of severe obesity in the pediatric population and adolescents has focused on a multidisciplinary approach involving diet, exercise, behavioral modification, and to some extent, pharmaceuticals. Although nonsurgical strategies provide a certain degree of effective weight reduction, most of the severely obese adolescents suffer from a high relapse ... Read more >>

J Obes Metab Syndr (Journal of obesity & metabolic syndrome)
[2020, :]

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Successful liver transplantation in short telomere syndromes without bone marrow failure due to DKC1 mutation.

Rodrigo Del Brío Castillo, Jacob Bleesing, Thomas McCormick, James E Squires, George V Mazariegos, Judy Squires, Patrick J McKiernan,

Short telomere syndromes are a heterogenous spectrum of disorders leading to premature cellular aging. These may involve bone marrow failure, adult-onset idiopathic pulmonary fibrosis, and liver disease, and classical entities such as dyskeratosis congenita. We report a patient who presented with common variable immunodeficiency at 3 years of age and autoimmune ... Read more >>

Pediatr Transplant (Pediatric transplantation)
[2020, :e13695]

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