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Full Text Journal Articles about
Peak Flow Rate Measurement

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Serial evaluation of cardiac biomarker NT-proBNP with speckle tracking echocardiography in a 6-year-old Golden Retriever dog with subaortic stenosis and dilated cardiomyopathy.

Woong-Bin Ro, Min-Hee Kang, Hee-Myung Park,

Vet Q (The veterinary quarterly)
[2020, 40(1):77-82]

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Further validation of strecker-type α-aminonitriles as a new class of potent human carbonic anhydrase II inhibitors: hit expansion within the public domain using differential scanning fluorimetry leads to chemotype refinement.

Mikhail Krasavin, Stanislav Kalinin, Sergey Zozulya, Anastasia Griniukova, Petro Borysko, Andrea Angeli, Claudiu T Supuran,

Testing of an expanded, 800-compound set of analogues of the earlier described Strecker-type α-aminonitriles (selected from publicly available Enamine Ltd. Screening Collection) in thermal shift assay against bovine carbonic anhydrase (bCA) led to further validation of this new class of inhibitors and identification a new, refined chemotype represented by inhibitors ... Read more >>

J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2020, 35(1):165-171]

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Minocycline-loaded PLGA electrospun membrane prevents alveolar bone loss in experimental peridontitis.

Yihui Ma, Jinlin Song, Huthayfa N S Almassri, Dan Zhang, Ting Zhang, Yuting Cheng, Xiaohong Wu,

Minocycline (MINO) is a tetracycline antibiotic effective against most of the bacteria microorganisms related to periodontal disease. Additionally, MINO promotes bone in vitro and in vivo. The objective of the present study was to establish the protocol for the preparation of MINO-loaded poly (lactic-co-glycolic acid) (MINO-PLGA) electrospun membranes and to evaluate their ... Read more >>

Drug Deliv (Drug delivery)
[2020, 27(1):151-160]

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Determinants of Lung Function at Age 8.5 Years in a Birth Cohort of Thai Children.

Wanaporn Anuntaseree, Kanokpan Ruangnapa, Pasuree Sangsupawanich, Ladda Mo-Suwan, Kantara Saelim, Nannapat Pruphetkaew,

BACKGROUND AND AIMS:Early life factors have reported the associations with impaired lung function in later life. In the present study, the birth cohort was followed up longitudinally to investigate the determinants of lung function in Thai children. METHODS:Cohort subjects were recruited from children born in Songkhla Province in southern Thailand. ... Read more >>

J. Trop. Pediatr. (Journal of tropical pediatrics)
[2020, 66(2):144-151]

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Standardized image interpretation and post-processing in cardiovascular magnetic resonance - 2020 update : Society for Cardiovascular Magnetic Resonance (SCMR): Board of Trustees Task Force on Standardized Post-Processing.

Jeanette Schulz-Menger, David A Bluemke, Jens Bremerich, Scott D Flamm, Mark A Fogel, Matthias G Friedrich, Raymond J Kim, Florian von Knobelsdorff-Brenkenhoff, Christopher M Kramer, Dudley J Pennell, Sven Plein, Eike Nagel,

With mounting data on its accuracy and prognostic value, cardiovascular magnetic resonance (CMR) is becoming an increasingly important diagnostic tool with growing utility in clinical routine. Given its versatility and wide range of quantitative parameters, however, agreement on specific standards for the interpretation and post-processing of CMR studies is required ... Read more >>

J Cardiovasc Magn Reson (Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance)
[2020, 22(1):19]

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Peripheral Determinants of Oxygen Utilization in Heart Failure With Preserved Ejection Fraction: Central Role of Adiposity.

Payman Zamani, Elizabeth A Proto, Jeremy A Mazurek, Stuart B Prenner, Kenneth B Margulies, Raymond R Townsend, Daniel P Kelly, Zoltan Arany, David C Poole, Peter D Wagner, Julio A Chirinos,

The aim of this study was to determine the arteriovenous oxygen content difference (ΔAVo2) in adult subjects with and without heart failure with preserved ejection fraction (HFpEF) during systemic and forearm exercise. Subjects with HFpEF had reduced ΔAVo2. Forearm diffusional conductance for oxygen, a lumped conductance parameter that incorporates all ... Read more >>

JACC Basic Transl Sci (JACC: Basic to Translational Science)
[2020, 5(3):211-225]

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Subclinical impairment of dynamic left ventricular systolic and diastolic function in patients with obstructive sleep apnea and preserved left ventricular ejection fraction.

Antonello D’Andrea, Angelo Canora, Simona Sperlongano, Domenico Galati, Serena Zanotta, Giorgio Emanuele Polistina, Carmine Nicoletta, Giacomo Ghinassi, Maurizio Galderisi, Alessandro Sanduzzi Zamparelli, Patrizio Lancellotti, Marialuisa Bocchino,

BackgroundHypoxia affects myocardial oxygen supply resulting in subclinical cardiac dysfunction in obstructive sleep apnea (OSA) patients, with cardiovascular complications being associated with increased oxidative burst (OB). The aims of our study were to assess left ventricular (LV) dynamic myocardial deformation and diastolic reserve at rest and upon exercise, along with ... Read more >>

BMC Pulm Med (BMC Pulmonary Medicine)
[2020, 20:]

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Prevalence and predictors of suboptimal peak inspiratory flow rate in COPD patients.

Hadeer S Harb, Nabila Ibrahim Laz, Hoda Rabea, Mohamed E A Abdelrahim,

The aim of this study was to determine prevalence and possible clinical predictors of suboptimal peak inspiratory flow rate (PIFR) with different dry powder inhalers. PIFR was measured across all resistance ranges of In-Check Dial® in 180 chronic obstructive pulmonary disease (COPD) subjects before hospital discharge. COPD subjects were defined ... Read more >>

Eur J Pharm Sci (European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences)
[2020, 147:105298]

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Estimating intracranial pressure using pulsatile cerebral blood flow measured with diffuse correlation spectroscopy.

Alexander Ruesch, Jason Yang, Samantha Schmitt, Deepshikha Acharya, Matthew A Smith, Jana M Kainerstorfer,

Measuring intracranial pressure (ICP) is necessary for the treatment of severe head injury but measurement systems are highly invasive and introduce risk of infection and complications. We developed a non-invasive alternative for quantifying ICP using measurements of cerebral blood flow (CBF) by diffuse correlation spectroscopy. The recorded cardiac pulsation waveform ... Read more >>

Biomed Opt Express (Biomedical optics express)
[2020, 11(3):1462-1476]

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Echocardiographic evidence of left ventricular untwisting-filling interplay.

Amir Hodzic, Damien Garcia, Eric Saloux, Paula A B Ribeiro, Amélie Ethier, James D Thomas, Paul Milliez, Hervé Normand, Francois Tournoux,

BACKGROUND:Left ventricular untwisting generates an early diastolic intraventricular pressure gradient (DIVPG) than can be quantified by echocardiography. We sought to confirm the quantitative relationship between peak untwisting rate and peak DIVPG in a large adult population. METHODS:From our echocardiographic database, we retrieved all the echocardiograms with a normal left ventricular ... Read more >>

Cardiovasc Ultrasound (Cardiovascular ultrasound)
[2020, 18(1):8]

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Effects of 3 Weeks Yogic Breathing Practice on Ventilation and Running Economy.

Christie L Seltmann, Lauren G Killen, James M Green, Eric K O'Neal, Jon C Swain, Chris M Frisbie,

Yogic breathing techniques (Pranayama) positively impact respiratory function (RF) in non-endurance trained individuals. The purpose of this study investigated effects of routine Pranayama practice on RF, running economy (RE) and perceptual responses. A between subject's case-control study design was incorporated. Eleven runners practiced three styles of Pranayama (30 min/day 6 ... Read more >>

Int J Exerc Sci (International journal of exercise science)
[2020, 13(2):62-74]

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Relationship between pulmonary function, throw distance, and psychological competitive ability of elite highly trained Japanese boccia players via correlation analysis.

Tomomi Ichiba, Kuniharu Okuda, Tetsuo Miyagawa, Masataka Kataoka, Kousuke Yahagi,

Background:Boccia players have severe quadriplegia; nonetheless, detailed aspects of the physical function of individual players have not been evaluated. Aims:This study aimed to detetmine the relationship between pulmonary function, pitching distance, and psychological competitive ability of Japanese boccia players. Methods:Participants were athletes from the Japan Boccia Association (10 males, 3 ... Read more >>

Heliyon (Heliyon)
[2020, 6(3):e03581]

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Microcirculatory dysfunction and dead-space ventilation in early ARDS: a hypothesis-generating observational study.

Gustavo A Ospina-Tascón, Diego F Bautista, Humberto J Madriñán, Juan D Valencia, William F Bermúdez, Edgardo Quiñones, Luis Eduardo Calderón-Tapia, Glenn Hernandez, Alejandro Bruhn, Daniel De Backer,

BACKGROUND:Ventilation/perfusion inequalities impair gas exchange in acute respiratory distress syndrome (ARDS). Although increased dead-space ventilation (VD/VT) has been described in ARDS, its mechanism is not clearly understood. We sought to evaluate the relationships between dynamic variations in VD/VT and extra-pulmonary microcirculatory blood flow detected at sublingual mucosa hypothesizing that an ... Read more >>

Ann Intensive Care (Annals of Intensive Care)
[2020, 10(1):35]

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Habitual cigarette smoking attenuates shear-mediated dilation in the brachial artery but not in the carotid artery in young adults.

Kazuya Suzuki, Takuro Washio, Shingo Tsukamoto, Kazunori Kato, Erika Iwamoto, Shigehiko Ogoh,

In the present study, we hypothesized that habitual cigarette smoking attenuates endothelial function in the cerebral circulation as well as that of the peripheral circulation in young adults. To test this hypothesis, we measured cerebrovascular and peripheral flow-mediated dilation (FMD) in young smokers and nonsmokers in the present study. Ten ... Read more >>

Physiol Rep (Physiological reports)
[2020, 8(3):e14369]

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Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response.

Shamim A K Chowdhury, Chad M Warren, Jillian N Simon, David M Ryba, Ashley Batra, Peter Varga, Evangelia G Kranias, Jil C Tardiff, R John Solaro, Beata M Wolska,

Hypertrophic cardiomyopathy (HCM) is a genetic disorder caused by mutations in different genes mainly encoding myofilament proteins and therefore called a "disease of the sarcomere." Despite the discovery of sarcomere protein mutations linked to HCM almost 30 years ago, the cellular mechanisms responsible for the development of this disease are ... Read more >>

Front Physiol (Frontiers in Physiology)
[2020, 11:107]

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Cardiovascular magnetic resonance 4D flow analysis has a higher diagnostic yield than Doppler echocardiography for detecting increased pulmonary artery pressure.

Joao G Ramos, Alexander Fyrdahl, Björn Wieslander, Gert Reiter, Ursula Reiter, Ning Jin, Eva Maret, Maria Eriksson, Kenneth Caidahl, Peder Sörensson, Andreas Sigfridsson, Martin Ugander,

BACKGROUND:Pulmonary hypertension is definitively diagnosed by the measurement of mean pulmonary artery (PA) pressure (mPAP) using right heart catheterization. Cardiovascular magnetic resonance (CMR) four-dimensional (4D) flow analysis can estimate mPAP from blood flow vortex duration in the PA, with excellent results. Moreover, the peak systolic tricuspid regurgitation (TR) pressure gradient ... Read more >>

BMC Med Imaging (BMC medical imaging)
[2020, 20(1):28]

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Acute alterations in glucose homeostasis impact coronary microvascular function in patients presenting with ST-segment elevation myocardial infarction.

M A van Lavieren, M Bax, V E Stegehuis, T P van de Hoef, G W M Wijntjens, R J de Winter, K T Koch, J P S Henriques, M Meuwissen, K D Sjauw, J J Piek,

BACKGROUND:Microvascular dysfunction in the setting of ST-segment myocardial infarction (STEMI) is thought to be related to stress-related metabolic changes, including acute glucose intolerance. The aim of this study was to assess the relationship between admission glucose levels and microvascular function in non-diabetic STEMI patients. METHODS:92 consecutive patients with a first anterior-wall ... Read more >>

Neth Heart J (Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation)
[2020, 28(3):161-170]

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Quantitative and Dynamic MRI Measures of Peripheral Vascular Function.

Erin K Englund, Michael C Langham,

The endothelium regulates and mediates vascular homeostasis, allowing for dynamic changes of blood flow in response to mechanical and chemical stimuli. Endothelial dysfunction underlies many diseases and is purported to be the earliest pathologic change in the progression of atherosclerotic disease. Peripheral vascular function can be interrogated by measuring the ... Read more >>

Front Physiol (Frontiers in Physiology)
[2020, 11:120]

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Associations Between Bioaerosol Exposures and Lung Function Changes Among Dairy Workers in Colorado.

Sheena E Martenies, Joshua Schaeffer, Grant Erlandson, Mary Bradford, Jill A Poole, Ander Wilson, Zachary Weller, Stephen Reynolds, Sheryl Magzamen,

OBJECTIVE:Limited studies have examined effects of bioaerosols on the respiratory health of dairy workers; previous findings have been inconsistent across populations. METHODS:Using a repeated measures design, exposures to dust, bioaerosols, and ozone were assessed and pre- and post-shift spirometry was performed for dairy workers (n = 36). Workers completed 1 to 8 ... Read more >>

J. Occup. Environ. Med. (Journal of occupational and environmental medicine)
[2020, :]

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The Utility of Cardiac Reserve for the Early Detection of Cancer Treatment-Related Cardiac Dysfunction: A Comprehensive Overview.

Stephen Foulkes, Guido Claessen, Erin J Howden, Robin M Daly, Steve F Fraser, Andre La Gerche,

With progressive advancements in cancer detection and treatment, cancer-specific survival has improved dramatically over the past decades. Consequently, long-term health outcomes are increasingly defined by comorbidities such as cardiovascular disease. Importantly, a number of well-established and emerging cancer treatments have been associated with varying degrees of cardiovascular injury that may ... Read more >>

Front Cardiovasc Med (Frontiers in Cardiovascular Medicine)
[2020, 7:32]

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Non-invasive MRI quantification of cerebrospinal fluid dynamics in amyotrophic lateral sclerosis patients.

Lucas R Sass, Mohammadreza Khani, Jacob Romm, Marianne Schmid Daners, Kyle McCain, Tavara Freeman, Gregory T Carter, Douglas L Weeks, Brian Petersen, Jason Aldred, Dena Wingett, Bryn A Martin,

BACKGROUND:Developing novel therapeutic agents to treat amyotrophic lateral sclerosis (ALS) has been difficult due to multifactorial pathophysiologic processes at work. Intrathecal drug administration shows promise due to close proximity of cerebrospinal fluid (CSF) to affected tissues. Development of effective intrathecal pharmaceuticals will rely on accurate models of how drugs are ... Read more >>

Fluids Barriers CNS (Fluids and barriers of the CNS)
[2020, 17(1):4]

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Multimodal Monitoring of Cardiovascular Responses to Postural Changes.

Arjen Mol, Andrea B Maier, Richard J A van Wezel, Carel G M Meskers,

Background:In the poorly understood relationship between orthostatic hypotension and falls, next to blood pressure (BP), baroreflex sensitivity (BRS) and cerebral autoregulation (CAR) may be key measures. The posture- and movement dependency of orthostatic hypotension requires continuous and unobtrusive monitoring. This may be possible using simultaneous photoplethysmography (PPG), electrocardiography (ECG), and ... Read more >>

Front Physiol (Frontiers in Physiology)
[2020, 11:168]

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Automated Quantitative Extraction and Analysis of 4D flow Patterns in the Ascending Aorta: An intraindividual comparison at 1.5 T and 3 T.

Sebastian Ebel, Josefin Dufke, Benjamin Köhler, Bernhard Preim, Benjamin Behrendt, Boris Riekena, Bernd Jung, Christian Stehning, Siegfried Kropf, Matthias Grothoff, Matthias Gutberlet,

4D flow MRI enables quantitative assessment of helical flow. Current methods are susceptible to noise. To evaluate helical flow patterns in healthy volunteers and patients with bicuspid aortic valves (BAV) at 1.5 T and 3 T using pressure-based helix-extraction in 4D flow MRI. Two intraindividual 4D flow MRI examinations were performed at ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):2949]

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The Predictive Value of Endothelial Inflammatory Markers in the Onset of Schizophrenia.

Gabriela Radu, Constantin Luca, Lucian Petrescu, Diana Aurora Bordejevic, Mirela Cleopatra Tomescu, Minodora Andor, Ioana Cîtu, Adelina Mavrea, Valentina Buda, Cătălin Tomescu, Florin Borcan, Liana Dehelean,

Purpose:This study aimed to assess the serum levels of intracellular adhesion molecule (sICAM-1), and vascular cell adhesion molecule (sVCAM-1), in the first psychotic episode schizophrenia (SZ) patients, before and after six months of antipsychotic treatment. Patients and Methods:The study included 50 patients with a first hospitalization for SZ and 50 ... Read more >>

Neuropsychiatr Dis Treat (Neuropsychiatric Disease and Treatment)
[2020, 16:545-555]

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Establishment of Reference Norms for Lung Function Parameters of Healthy Sri Lankan Tamils.

Mathanki Sooriyakanthan, Savithri Wimalasekera, Sivapalan Kanagasabai,

Spirometry and Peak Expiratory Flow Rate (PEFR) are important measurements in diagnosing and monitoring of COPD and asthma. Ethnic specific reference equations are necessary in interpretation of these parameters. However, equations for Sri Lankan Tamil adults are not available. This study aims to establish reference equations for lung function parameters ... Read more >>

Pulm Med (Pulmonary medicine)
[2019, 2019:2169627]

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