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Evaluation of the effects of preconditioned human stem cells plus a scaffold and photobiomodulation administration on stereological parameters and gene expression levels in a critical size bone defect in rats.

Armin Khosravipour, Abdollah Amini, Reza Masteri Farahani, Atarodalsadat Mostafavinia, Mehrdad Asgari, Fatemehalsadat Rezaei, Heidi Abrahamse, Sufan Chien, Mohammad Bayat,

We assessed the impact of photobiomodulation (PBM) plus adipose-derived stem cells (ASCs) during the anabolic and catabolic stages of bone healing in a rat model of a critical size femoral defect (CSFD) that was filled with a decellularized bone matrix (DBM). Stereological analysis and gene expression levels of bone morphogenetic ... Read more >>

Lasers Med Sci (Lasers in medical science)
[2022, :]

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Photobiomodulation of gingival lesions resulting from autoimmune diseases: systematic review and meta-analysis.

Milena Moraes de Carvalho, Marco Antonio Rimachi Hidalgo, Raquel Mantuaneli Scarel-Caminaga, Noé Vital Ribeiro Junior, Felipe Fornias Sperandio, Suzane Cristina Pigossi, Marina Lara de Carli,

<h4>Objectives</h4>To evaluate the effects of photobiomodulation (PBM) in gingival lesions resulting from autoimmune diseases; to compare PBM and topical corticosteroid (CS) treatment; and to assess PBM outcome over time of follow-up.<h4>Materials and methods</h4>A comprehensive electronic search was performed in four electronic databases. Treatment effects were measured through visual analog scale ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2022, :]

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Microbiome Changes in Humans with Parkinson’s Disease after Photobiomodulation Therapy: A Retrospective Study

Brian Bicknell, Ann Liebert, Craig S. McLachlan, Hosen Kiat,

There is a paucity of information on the effect of photobiomodulation therapy on gut microbiome composition. Parkinson’s disease is a progressive neurological disorder with few management options, although the gut microbiome has been suggested as a potential avenue of treatment. We retrospectively analysed the microbiome from human stool samples from ... Read more >>

J Pers Med (Journal of personalized medicine)
[2022, 12(1):]

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Effects of Photobiomodulation and Split-Thickness Skin Grafting in the Prognosis of Wound Healing in Children with Deep Burn Ulcers.

Nooshafarin Kazemikhoo, Tayyeb Ghadimi, Reza Vaghardoost, Mahnoush Momeni, Mohammad Ali Nilforoushzadeh, Fereshteh Ansari, Mostafa Dahmardehei,

<b><i>Background:</i></b> Split-thickness skin grafting (STSG) is a standard therapeutic technique in patients with extensive and deep ulcers. Hospitalization and surgery can result in complications, especially in children. Photobiomodulation (PBM) has been applied in a variety of conditions such as healing of surgical, venous, pressure, and diabetic wounds, but no clinical ... Read more >>

Photobiomodul Photomed Laser Surg (Photobiomodulation, photomedicine, and laser surgery)
[2022, :]

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A review of European guidelines for patient blood management with a particular emphasis on antifibrinolytic drug administration for cardiac surgery.

Andrew Klein, Seema Agarwal, Bernard Cholley, Jens Fassl, Michael Griffin, Timo Kaakinen, Patrick Paulus, Steffen Rex, Martin Siegemund, Annewil van Saet,

The concept of patient blood management (PBM) was introduced by the World Health Organization in 2011 and is defined as a "patient-focused, evidence-based and systematic approach for optimizing the management of patients and transfusion of blood products to ensure high quality and effective patient care". Patient blood management is a ... Read more >>

J Clin Anesth (Journal of clinical anesthesia)
[2022, 78:110654]

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An Anatomical Study of the Palmaris Brevis, Transverse Carpal Ligament, and the Recurrent Motor Branch of the Median Nerve.

Yong Seok Nam, EunAh Hong, BumSik Kim, JungSoo Yoon, SooA Lim, YeaSik Han, SuRak Eo,

<b>Background:</b> The anatomical structures in relation to the carpal tunnel release are the palmaris brevis muscle (PBM), transverse carpal ligament (TCL), and the recurrent motor branch of the median nerve (RMBMN). Our aim is to describe the gross morphology in the Korean population of the PBM, TCL, and RMBMN specifically ... Read more >>

J Hand Surg Asian Pac Vol (The journal of hand surgery Asian-Pacific volume)
[2022, :2250008]

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Benefits of a Skull-Interfaced Flexible and Implantable Multilight Emitting Diode Array for Photobiomodulation in Ischemic Stroke.

Hyunha Kim, Min Jae Kim, Young Woo Kwon, Sangheon Jeon, Seo-Yeon Lee, Chang-Seok Kim, Byung Tae Choi, Yong-Il Shin, Suck Won Hong, Hwa Kyoung Shin,

Photobiomodulation (PBM) has received attention due to its potential for improving tissue function and enhancing regeneration in stroke. A lightweight, compact, and simple system of miniaturized electronic devices consisting of packaged light-emitting diodes (LEDs) that incorporates a flexible substrate for in vivo brain PBM in a mouse model is developed. ... Read more >>

Adv Sci (Weinh) (Advanced science (Weinheim, Baden-Wurttemberg, Germany))
[2022, :e2104629]

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Focused educational intervention improves intern knowledge of perioperative patient blood management principles.

Kerstin Wyssusek, Kate Taylor, Sandra Concha-Blamey,

A perioperative patient blood management (PBM) educational intervention was implemented for first year postgraduate doctors (interns) at the Royal Brisbane and Women's Hospital (RBWH) following identification of a perioperative PBM training requirement. This quality improvement activity evaluated the effectiveness of this educational intervention in improving intern knowledge of perioperative PBM ... Read more >>

BMJ Open Qual (BMJ open quality)
[2021, 10(4):]

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Evaluation of Gender Differences in Response to Photobiomodulation Therapy, Including Laser Acupuncture: A Narrative Review and Implication to Precision Medicine.

Ann Liebert, Neda Seyedsadjadi, Vincent Pang, Gerhard Litscher, Hosen Kiat,

<b><i>Background:</i></b> The influence of gender is significant in the manifestation and response to many diseases and in the treatment strategy. Photobiomodulation (PBM) therapy, including laser acupuncture, is an evidence-based treatment and disease prevention modality that has shown promising efficacy for a myriad of chronic and acute diseases. Anecdotal experience and ... Read more >>

Photobiomodul Photomed Laser Surg (Photobiomodulation, photomedicine, and laser surgery)
[2021, :]

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Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells.

Yuehou Zhang, Jianlong Su, Kui Ma, Haihong Li, Xiaobing Fu, Cuiping Zhang,

The application of photobiomodulation (PBM) in regenerative medicine has expanded to the treatment of alopecia caused by various reasons. However, the mechanisms responsible for its effects are poorly understood. Here, we aimed to investigate the effects of PBM on hair regeneration in injured skin and to explore the underlying mechanisms. ... Read more >>

Wound Repair Regen (Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society)
[2021, :]

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Narrative Review of Russian, Ukrainian and English-Language Publications Investigating the Effects of Photobiomodulation on Red Blood Cell Physiology.

Ann Liebert, Vincent Pang, Delina Caagby, Lucy Arshinikova, Hosen Kiat,

<b><i>Objective:</i></b> The beneficial effects of photobiomodulation (PBM) on cellular function are well characterized, principally deriving from the absorption of red to near-infrared radiation by chromophores such as cytochrome-c-oxidase. However, the effects and underlying mechanisms of PBM on non-mitochondria containing cells, such as red blood cells (RBCs), are relatively unknown. In ... Read more >>

Photobiomodul Photomed Laser Surg (Photobiomodulation, photomedicine, and laser surgery)
[2021, :]

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Nutritional Quality of Plant-Based Meat Products Available in the UK: A Cross-Sectional Survey.

Roberta Alessandrini, Mhairi K Brown, Sonia Pombo-Rodrigues, Sheena Bhageerutty, Feng J He, Graham A MacGregor,

Plant-based meat (PBM) has been gaining popularity due to increasing concerns over health, animal welfare, and environmental issues linked to animal foods. This study aimed to compare the nutrient profile of PBM with equivalent meat products. We conducted a cross-sectional survey of 207 PBM and 226 meat products available from ... Read more >>

Nutrients (Nutrients)
[2021, 13(12):]

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Improved healing and macrophage polarization in oral ulcers treated with photobiomodulation (PBM).

Hyun Seok Ryu, Nam Kyu Lim, Andrew Reyes Padalhin, Celine Abueva, So Young Park, Phil-Sang Chung, Seung Hoon Woo,

The effect of photobiomodulation (PBM) treatment on wound healing and macrophage polarization was investigated in vivo. Animal models of oral ulcers were simulated through chemically induced oral ulcers in rats. PBM treatment using an infrared pulsed laser was used to treat oral ulcers in the animal models. Twelve Sprague-Dawley rats ... Read more >>

Lasers Surg Med (Lasers in surgery and medicine)
[2021, :]

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Multiseptate gallbladder coexisting with pancreaticobiliary maljunction treated by laparoscopic cholecystectomy: report of a pediatric case.

Noboru Oyachi, Fuminori Numano, Keiichi Koizumi, Atsushi Takano, Hiroshi Shibusawa,

<h4>Background</h4>A multiseptate gallbladder is a very rare congenital malformation in which the lumen is divided into variously sized multiseptal compartments. The pathogenesis and natural history of this disease remain uncertain. We herein describe a pediatric case of a multiseptate gallbladder with pancreaticobiliary maljunction (PBM), which was treated by laparoscopic cholecystectomy.<h4>Case ... Read more >>

Surg Case Rep (Surgical case reports)
[2022, 8(1):16]

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Proliferation and differentiation of primary bovine myoblasts using Chlorella vulgaris extract for sustainable production of cultured meat.

Yuta Okamoto, Yuji Haraguchi, Azumi Yoshida, Hironobu Takahashi, Kumiko Yamanaka, Naoya Sawamura, Toru Asahi, Tatsuya Shimizu,

Recently, cultured meat obtained from livestock-derived cells is being considered as a sustainable food source that reduces the use of natural resources. This study aimed to show that nutrients extracted from Chlorella vulgaris were beneficial in the culture of primary bovine myoblasts (PBMs), a major cell source for cultured meat ... Read more >>

Biotechnol Prog (Biotechnology progress)
[2022, :e3239]

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Interactions of SARS-CoV-2 protein E with cell junctions and polarity PDZ-containing proteins

Yanlei Zhu, Flavio Alvarez, Nicolas Wolff, Ariel Mechaly, Sébastien Brûlé, Benoit Neitthoffer, Sandrine Etienne-Manneville, Ahmed Haouz, Batiste Boëda, Célia Caillet-Saguy,

The C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein E contains a PBM (PDZ binding motif) targeting PDZ (PSD-95/Dlg/ZO-1) domains identical to the PBM of SARS-CoV. The latter is involved in the pathogenicity of the virus. Recently, we identified ten human PDZ-containing proteins showing significant interactions with ... Read more >>

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Modifying the Microbiome as a Potential Mechanism of Photobiomodulation: A Case Report.

Brian Bicknell, E-Liisa Laakso, Ann Liebert, Hosen Kiat,

<b><i>Objective:</i></b> The objective of this case study was to elucidate the effect of photobiomodulation (PBM) on the microbiome. <b><i>Background:</i></b> The gut microbiome has been identified as a key component of health, with gut dysbiosis, characterized by decreased microbial diversity and an altered microbial composition, being recognized as instrumental in many ... Read more >>

Photobiomodul Photomed Laser Surg (Photobiomodulation, photomedicine, and laser surgery)
[2021, :]

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Photobiomodulation effect in tumoral necrosis factor-alpha(TNF-α) on the viability of random skin flap in rats.

Georgia Rodrigues Esteves, Ivaldo Esteves Junior, Igor Fagioli Bordello Masson, Aline Fernanda Perez Machado, Maria Carolina Derencio Oliveira, Cristiano Schiavinato Baldan, Thiago Saikali Farcic, Richard Eloin Liebano, Hélio Plapler,

The aim of this study was to investigate the effect of red laser (660 nm) photobiomodulation (PBM) with different energies on tumor necrosis factor-alpha(TNF-α) expression for random skin flap viability in rats. Twenty-four Wistar rats were divided into three groups: sham group (SG), PBM laser group with an energy dose ... Read more >>

Lasers Med Sci (Lasers in medical science)
[2022, :]

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Autophagy and Apoptosis Induced in U87 MG Glioblastoma Cells by Hypericin-Mediated Photodynamic Therapy Can Be Photobiomodulated with 808 nm Light.

Viktoria Pevna, Georges Wagnières, Veronika Huntosova,

Glioblastoma is one of the most aggressive types of tumors. Although few treatment options are currently available, new modalities are needed to improve prognosis. In this context, photodynamic therapy (PDT) is a promising adjuvant treatment modality. In the present work, hypericin-mediated PDT (hypericin-PDT, 2 J/cm<sup>2</sup>) of U87 MG cells is ... Read more >>

Biomedicines (Biomedicines)
[2021, 9(11):]

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Photobiomodulation and Sports: Results of a Narrative Review.

Laura Marinela Ailioaie, Gerhard Litscher,

Benefits of photobiomodulation (PBM) have been known for several decades. More recently, PBM applied in sports offers a special chance to support the modeling of the performance and recovery. Increasingly complex physical activities and fierce competition in the world of sports generate a state of psycho-emotional and physical stress that ... Read more >>

Life (Basel) (Life (Basel, Switzerland))
[2021, 11(12):]

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Bacillus cereus as a Major Cause of Discarded Pasteurized Human Banked Milk: A Single Human Milk Bank Experience.

Miroslava Jandová, Pavel Měřička, Michaela Fišerová, Aleš Landfeld, Pavla Paterová, Lenka Hobzová, Eva Jarkovská, Marian Kacerovský, Milan Houška,

A systematic study, performed from 2017-2020 looked at the rate of positive post-pasteurization <i>B. cereus</i> findings, the quantity of <i>B. cereus</i> in pasteurized banked human milk (PBM), and the rate of <i>B. cereus</i> toxicogenic isolates from PBM. During the study period, 6815.71 L (30,943 tested bottles) of PBM were tested, ... Read more >>

Foods (Foods (Basel, Switzerland))
[2021, 10(12):]

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Remote Photobiomodulation Treatment for the Clinical Signs of Parkinson's Disease: A Case Series Conducted During COVID-19.

Ann Liebert, Brian Bicknell, E-Liisa Laakso, Parastoo Jalilitabaei, Sharon Tilley, Hosen Kiat, John Mitrofanis,

Objective: To assess whether remote application of photobiomodulation (PBM) is effective in reducing clinical signs of Parkinson's disease (PD). Background: PD is a progressive neurodegenerative disease for which there is no cure and few treatment options. There is a strong link between the microbiome-gut-brain axis and PD. PBM in animal ... Read more >>

Photobiomodul Photomed Laser Surg (Photobiomodulation, photomedicine, and laser surgery)
[2021, :]

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808-nm Photobiomodulation Affects the Viability of a Head and Neck Squamous Carcinoma Cellular Model, Acting on Energy Metabolism and Oxidative Stress Production.

Silvia Ravera, Nadia Bertola, Claudio Pasquale, Silvia Bruno, Stefano Benedicenti, Sara Ferrando, Angelina Zekiy, Praveen Arany, Andrea Amaroli,

Photobiomodulation (PBM) is a form of low-dose light therapy that acts through energy delivery from non-ionizing sources. During the recent two decades, there has been tremendous progress with PBM acceptance in medicine. However, PBM effects on potential stimulation of existing malignant or pre-malignant cells remain unknown. Thus, the primary endpoint ... Read more >>

Biomedicines (Biomedicines)
[2021, 9(11):]

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A population-based method to determine the time-integrated activity in molecular radiotherapy.

Deni Hardiansyah, Ade Riana, Peter Kletting, Nouran R R Zaid, Matthias Eiber, Supriyanto A Pawiro, Ambros J Beer, Gerhard Glatting,

BACKGROUND:The calculation of time-integrated activities (TIAs) for tumours and organs is required for dosimetry in molecular radiotherapy. The accuracy of the calculated TIAs is highly dependent on the chosen fit function. Selection of an adequate function is therefore of high importance. However, model (i.e. function) selection works more accurately when ... Read more >>

EJNMMI Phys (EJNMMI physics)
[2021, 8(1):82]

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Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.

Xuankang Wang, Xin Li, Xiaoshuang Zuo, Zhuowen Liang, Tan Ding, Kun Li, Yangguang Ma, Penghui Li, Zhijie Zhu, Cheng Ju, Zhihao Zhang, Zhiwen Song, Huilin Quan, Jiawei Zhang, Xueyu Hu, Zhe Wang,

<h4>Background</h4>Neurotoxic microglia and astrocytes begin to activate and participate in pathological processes after spinal cord injury (SCI), subsequently causing severe secondary damage and affecting tissue repair. We have previously reported that photobiomodulation (PBM) can promote functional recovery by reducing neuroinflammation after SCI, but little is known about the underlying mechanism. ... Read more >>

J Neuroinflammation (Journal of neuroinflammation)
[2021, 18(1):256]

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