Full Text Journal Articles about
Parkinson Plus Syndromes

Advertisement

Find full text journal articles






Fabry Disease With Concomitant Lewy Body Disease.

Kelly Del Tredici, Albert C Ludolph, Simone Feldengut, Christian Jacob, Heinz Reichmann, Jürgen R Bohl, Heiko Braak,

Although Gaucher disease can be accompanied by Lewy pathology (LP) and extrapyramidal symptoms, it is unknown if LP exists in Fabry disease (FD), another progressive multisystem lysosomal storage disorder. We aimed to elucidate the distribution patterns of FD-related inclusions and LP in the brain of a 58-year-old cognitively unimpaired male ... Read more >>

J. Neuropathol. Exp. Neurol. (Journal of neuropathology and experimental neurology)
[2020, 79(4):378-392]

Cited: 0 times

View full text PDF listing >>



The Broad Concept of “Spasticity-Plus Syndrome” in Multiple Sclerosis: A Possible New Concept in the Management of Multiple Sclerosis Symptoms.

Óscar Fernández, Lucienne Costa-Frossard, Marisa Martínez-Ginés, Paloma Montero, José Maria Prieto, Lluis Ramió,

Multiple sclerosis (MS) pathology progressively affects multiple central nervous system (CNS) areas. Due to this fact, MS produces a wide array of symptoms. Symptomatic therapy of one MS symptom can cause or worsen other unwanted symptoms (anticholinergics used for bladder dysfunction produce impairment of cognition, many MS drugs produce erectile ... Read more >>

Front Neurol (Frontiers in neurology)
[2020, 11:]

Cited: 0 times

View full text PDF listing >>



Advertisement

Randomized pilot trial for the efficacy of the MMF07 foot massager and heat therapy for restless legs syndrome.

Ariane Park, Katherine Ambrogi, Erinn M Hade,

Restless Legs Syndrome (RLS) is a sensorimotor condition with a wide range of severity. Symptoms negatively affect sleep and quality of life. Pharmacologic options are not universally effective and side effects are common. Objective data regarding non-pharmacologic treatment is limited. The study objective was to evaluate the efficacy of the ... Read more >>

PLoS ONE (PloS one)
[2020, 15(4):e0230951]

Cited: 0 times

View full text PDF listing >>



Discriminative Pattern of Reduced Cerebral Blood Flow in Parkinson's Disease and Parkinsonism-Plus Syndrome: an ASL-MRI study

Jun Shen, Lina Cheng, Xiaoyan Wu, Ruomi Guo, Yuzhou Wang, Wensheng Wang, Peng He, Hanbo Lin,

<title>Abstract</title> <p> <bold>Background:</bold> Accurate identification of Parkinson's disease (PD) and Parkinsonism-Plus syndrome (PPS), especially in the early stage of the disease, is very important. The purpose of this study was to investigate the discriminative spatial pattern of cerebral blood flow (CBF) between patients with PD and PPS.<bold>Methods: </bold>Arterial ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Serum adiponectin levels between patients with Parkinson's disease and those with PSP.

Hiroshi Kataoka, Kazuma Sugie,

INTRODUCTION:Adiponectin receptors are expressed in the hypothalamus, brainstem, and basal ganglia. Experimentally, adiponectin was immunopositive in the phosphorylated α-synuclein-positive Lewy bodies in the brain of individuals with Parkinson's disease (PD), and treatment with recombinant adiponectin suppressed the aggregation of α-synuclein. The close relationship between adiponectin and PD is suggested. METHODS:We ... Read more >>

Neurol. Sci. (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Levosulpiride-Induced Neurological Adverse Effects: A Prospective Study from a Tertiary Care Center.

Jacob Joe,

Background:Levosulpiride (LS) is a prokinetic drug increasingly used for the gastric motility disorders. Despite its common use for the gastric motility disorder, the tendency to cause parkinsonism and acute dystonias are under-recognized as the major adverse effects. This study was aimed to evaluate the adverse effects of this drug in ... Read more >>

Ann Indian Acad Neurol (Annals of Indian Academy of Neurology)
[2020, 23(2):174-176]

Cited: 0 times

View full text PDF listing >>



Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium.

Toji Miyagawa, Danielle Brushaber, Jeremy Syrjanen, Walter Kremers, Julie Fields, Leah K Forsberg, Hilary W Heuer, David Knopman, John Kornak, Adam Boxer, Howie Rosen, Bradley Boeve, ,

INTRODUCTION:Behavior/Comportment/Personality (BEHAV) and Language (LANG) domains were added to the Clinical Dementia Rating (CDR®) for improving evaluation of patients with frontotemporal lobar degeneration (FTLD) (CDR® plus NACC FTLD). METHODS:We analyzed the CDR® plus NACC FTLD among participants from the baseline visit of the Advancing Research and Treatment for Frontotemporal Lobar ... Read more >>

Alzheimers Dement (Alzheimer's & dementia : the journal of the Alzheimer's Association)
[2020, 16(1):79-90]

Cited: 0 times

View full text PDF listing >>



Association Between Hormone-Modulating Breast Cancer Therapies and Incidence of Neurodegenerative Outcomes for Women With Breast Cancer.

Gregory L Branigan, Maira Soto, Leigh Neumayer, Kathleen Rodgers, Roberta Diaz Brinton,

Importance:The association between exposure to hormone-modulating therapy (HMT) as breast cancer treatment and neurodegenerative disease (NDD) is unclear. Objective:To determine whether HMT exposure is associated with the risk of NDD in women with breast cancer. Design, Setting, and Participants:This retrospective cohort study used the Humana claims data set from January ... Read more >>

JAMA Netw Open (JAMA network open)
[2020, 3(3):e201541]

Cited: 0 times

View full text PDF listing >>



Pallidal Activity in Cervical Dystonia with and Without Head Tremor.

Alexey Sedov, Svetlana Usova, Ulia Semenova, Anna Gamaleya, Alexey Tomskiy, Sinem B Beylergil, H A Jinnah, Aasef G Shaikh,

The relationship between two common movement disorders, dystonia and tremor, is controversial. Both deficits have correlates in the network that includes connections between the cerebellum and the basal ganglia. In order to assess the physiological relationship between tremor and dystonia, we measured the activity of 727 pallidal single-neurons during deep ... Read more >>

Cerebellum (Cerebellum (London, England))
[2020, :]

Cited: 0 times

View full text PDF listing >>



Executive Function Is Related to the Urinary Urgency in Non-demented Patients With Parkinson's Disease.

Zuzanna Tkaczynska, Sara Becker, Walter Maetzler, Maarten Timmers, Luc Van Nueten, Patricia Sulzer, Giacomo Salvadore, Eva Schäffer, Kathrin Brockmann, Johannes Streffer, Daniela Berg, Inga Liepelt-Scarfone,

Introduction: Evidence suggests urinary urgency is associated with cognitive impairment in a subtype of Parkinson's disease (PD) patients. This study investigates if cognitive impairment independently predicts the presence of urinary dysfunction. Methods: We report data of 189 idiopathic PD patients, excluding those with concomitant diseases or medication interacting with bladder ... Read more >>

Front Aging Neurosci (Frontiers in Aging Neuroscience)
[2020, 12:55]

Cited: 0 times

View full text PDF listing >>



Essential tremor-plus: a controversial new concept.

Elan D Louis, Martin Bares, Julian Benito-Leon, Stanley Fahn, Steven J Frucht, Joseph Jankovic, William G Ondo, Pramod K Pal, Eng-King Tan,

In addition to redefining essential tremor (ET), the 2018 consensus statement of the Movement Disorder Society on tremor coined a new term: essential tremor-plus (ET-plus). This term is uncertainly defined as tremor with the characteristics of ET, with additional neurological signs of uncertain clinical significance. If ET-plus had been defined ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2020, 19(3):266-270]

Cited: 0 times

View full text PDF listing >>



Tracking disease progression in familial and sporadic frontotemporal lobar degeneration: Recent findings from ARTFL and LEFFTDS.

Howard J Rosen, Bradley F Boeve, Adam L Boxer,

INTRODUCTION:Familial frontotemporal lobar degeneration (f-FTLD) due to autosomal dominant mutations is an important entity for developing treatments for FTLD. The Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) and Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) longitudinal studies were designed to describe the natural history of f-FTLD. METHODS:We ... Read more >>

Alzheimers Dement (Alzheimer's & dementia : the journal of the Alzheimer's Association)
[2020, 16(1):71-78]

Cited: 0 times

View full text PDF listing >>



Secondary Parkinson disease caused by breast cancer during pregnancy: A case report.

Lei Li,

BACKGROUND:Paraneoplastic neurological syndrome manifesting as secondary Parkinson disease caused by breast cancer is extremely rare. CASE SUMMARY:We report a 39-year-old primipara of 31 gestational weeks, who presented with worsening tremors, facial stiffness and speech disfluencies, and decreased limb strength. Thorough physical examinations and auxiliary tests suggested secondary Parkinson's disease, but ... Read more >>

World J Clin Cases (World journal of clinical cases)
[2019, 7(23):4052-4056]

Cited: 0 times

View full text PDF listing >>



Clinical and Genetic Heterogeneity in a Cohort of Chinese Children With Dopa-Responsive Dystonia.

Yan Chen, Xinhua Bao, Yongxin Wen, Jiaping Wang, Qingping Zhang, Jiayou Yan,

Background: The aim of this study was to investigate the genetic and clinical features of dopa-responsive dystonia (DRD) in China. Method: Characteristics of gene mutations and clinical manifestations of 31 patients diagnosed with DRD were analyzed retrospectively. Result: From January 2000 to January 2019, 31 patients were diagnosed with DRD. ... Read more >>

Front Pediatr (Frontiers in Pediatrics)
[2020, 8:83]

Cited: 0 times

View full text PDF listing >>



Cognition in multiple system atrophy: a single-center cohort study.

Sabine Eschlböck, Margarete Delazer, Florian Krismer, Thomas Bodner, Alessandra Fanciulli, Beatrice Heim, Antonio Heras Garvin, Christine Kaindlstorfer, Elfriede Karner, Katherina Mair, Christoph Rabensteiner, Cecilia Raccagni, Klaus Seppi, Werner Poewe, Gregor K Wenning,

OBJECTIVE:Cognitive impairment in multiple system atrophy (MSA) is common, but remain poorly characterized. We evaluated cognitive and behavioral features in MSA patients and assessed between-group differences for MSA subtypes and the effect of orthostatic hypotension (OH) on cognition. METHODS:This retrospective study included 54 patients with clinical diagnosis of possible and ... Read more >>

Ann Clin Transl Neurol (Annals of clinical and translational neurology)
[2020, 7(2):219-228]

Cited: 0 times

View full text PDF listing >>



New phenotype of DCTN1-related spectrum: early-onset dHMN plus congenital foot deformity.

Wo-Tu Tian, Li-Hua Liu, Hai-Yan Zhou, Chao Zhang, Fei-Xia Zhan, Ze-Yu Zhu, Sheng-Di Chen, Xing-Hua Luan, Li Cao,

OBJECTIVE:To describe the clinical and genetic features of two patients with different phenotypes due to various Dynactin 1 (DCTN1) gene mutations and further explore the phenotype-genotype relationship. METHODS:Patient 1 is a 23-year-old man with congenital foot deformity and life-long distal muscle weakness and atrophy. Patient 2 is a 48-year-old woman ... Read more >>

Ann Clin Transl Neurol (Annals of clinical and translational neurology)
[2020, 7(2):200-209]

Cited: 0 times

View full text PDF listing >>



Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.

Phillip Smethurst, Emmanuel Risse, Giulia E Tyzack, Jamie S Mitchell, Doaa M Taha, Yun-Ru Chen, Jia Newcombe, John Collinge, Katie Sidle, Rickie Patani,

Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease caused by motor neuron loss, resulting in muscle wasting, paralysis and eventual death. A key pathological feature of ALS is cytoplasmically mislocalized and aggregated TDP-43 protein in >95% of cases, which is considered to have prion-like properties. Historical studies ... Read more >>

Brain (Brain : a journal of neurology)
[2020, 143(2):430-440]

Cited: 0 times

View full text PDF listing >>



Much More Than a Scaffold: Cytoskeletal Proteins in Neurological Disorders.

Diana C Muñoz-Lasso, Carlos Romá-Mateo, Federico V Pallardó, Pilar Gonzalez-Cabo,

Recent observations related to the structure of the cytoskeleton in neurons and novel cytoskeletal abnormalities involved in the pathophysiology of some neurological diseases are changing our view on the function of the cytoskeletal proteins in the nervous system. These efforts allow a better understanding of the molecular mechanisms underlying neurological ... Read more >>

Cells (Cells)
[2020, 9(2):]

Cited: 0 times

View full text PDF listing >>



Early Recognition and Diagnosis of Parkinson Disease and Ongoing Assessments.

Stuart H Isaacson,

Parkinson's disease (PD) is diagnosed when patients meet motor symptom criteria (bradykinesia plus tremor or rigidity). However, patients may demonstrate prodromal nonmotor symptoms 5-20 years prior to diagnosis. While motor symptoms are of concern, patients often consider nonmotor symptoms to be just as bothersome. In this brief CME activity, diagnostic ... Read more >>

J Clin Psychiatry (The Journal of clinical psychiatry)
[2019, 81(1):]

Cited: 0 times

View full text PDF listing >>



The down-regulation of PP2Ac demethylation attenuates learning and memory impairment in Manganism

Cailing Lu, Bin Wu, Haiqing Cai, Shen Tang, Yilu Xu, Qianqian Shi, Lancheng Wei, Ling Meng, Xinhang Wang, Deqiang Xiao, Yunfeng Zou, Xiaobo Yang, Xiyi Li,

<title>Abstract</title> <p> Background: Protein phosphatase 2A (PP2A) is considered a potential therapeutic target for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), and catalytic unit methylation of PP2A that relies on methionine and its intermediate S-adenosylmethionine (SAM) regulates most of protein phosphorylation. Manganese overload caused ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



The N-formyl peptide receptors: contemporary roles in neuronal function and dysfunction.

Peter J G Cussell, Margarita Gomez Escalada, Nathaniel G N Milton, Andrew W J Paterson,

N-formyl peptide receptors (FPRs) were first identified upon phagocytic leukocytes, but more than four decades of research has unearthed a plethora of non-myeloid roles for this receptor family. FPRs are expressed within neuronal tissues and markedly in the central nervous system, where FPR interactions with endogenous ligands have been implicated ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(7):1191-1198]

Cited: 0 times

View full text PDF listing >>



The Advantages of Levodopa-Carbidopa Intestinal Gel for Patients with Advanced Parkinson's Disease: A Systematic Review.

Xing-Ru Zhang, Zhi-Yu Jiang, Zeng-Rui Zhang, Hui-Jun Chen, Ke Wu, Jin-Cai He, Cheng-Long Xie,

Background:Levodopa-carbidopa intestinal gel (LCIG) is a new type of administration that results in steadier levodopa plasma concentrations in advanced Parkinson's disease (PD) patients and effectively reduces poor mobility and dyskinesia. Methods:Electronic databases were searched up to January 1, 2018. The inclusion criteria for this review were as follows: LCIG vs ... Read more >>

Drug Des Devel Ther (Drug Design, Development and Therapy)
[2020, 14:845-854]

Cited: 0 times

View full text PDF listing >>



Vocal cord electromyographic correlates of stridor in multiple system atrophy phenotypes.

Massimiliano Todisco, Enrico Alfonsi, Ioannis Ugo Isaias, Roberta Zangaglia, Brigida Minafra, Giuseppe Cosentino, Michele Terzaghi, Nicoló Gabriele Pozzi, Raffaele Manni, Claudio Pacchetti,

INTRODUCTION:Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by dysautonomia in combination with parkinsonian and cerebellar signs. Stridor may also occur and it is associated with life-threatening events and poor prognosis. The pathophysiology of stridor in MSA is still debated. OBJECTIVE:To define correlations between diurnal electromyographic (EMG) abnormalities of ... Read more >>

Parkinsonism Relat. Disord. (Parkinsonism & related disorders)
[2020, 70:31-35]

Cited: 0 times

View full text PDF listing >>



Correction: An investigation into the impact and implications of published papers from retracted research: systematic search of affected literature.

BMJ Open (BMJ open)
[2019, 9(12):e031909corr1]

Cited: 0 times

View full text PDF listing >>



Editorial: Pathophysiologic Insights From Biomarker Studies in Neurological Disorders.

Stefan Bittner, Marcello Moccia, Tobias Warnecke, Tobias Ruck,

Front Neurol (Frontiers in Neurology)
[2020, 11:151]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
3.0297 s