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The plant terpenoid carvone is a chemotaxis repellent for C. elegans.

Clayton Ellington, Andrew Hayden, Zack LaGrange, Marina Luccioni, Mohammed Osman, Lauren Ramlan, Miranda Vogt, Sujay Guha, Miriam Goodman, Lauren O'Connell,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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unc-42 regulates the expression of ASH terminal fate markers.

Jordan Wood, Denise Ferkey,

(microPublication biology)
[2019, 2019:]

Cited: 1 time

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Analogues of 2'-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase.

Sri Devi Sukumaran, Shah Bakhtiar Nasir, Jia Ti Tee, Michael J C Buckle, Rozana Othman, Noorsaadah Abd Rahman, Vannajan Sanghiran Lee, Syed Nasir Abbas Bukhari, Chin Fei Chee,

A series of C4-substituted tertiary nitrogen-bearing 2'-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor. Majority of the 2'-hydroxychalcone analogues displayed a better inhibition against acetylcholinesterase (AChE) than butyrylcholinesterase (BuChE). Among them, compound 4c was identified as the most potent AChE inhibitor (IC50: 3.3 µM) and showed ... Read more >>

J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2021, 36(1):130-137]

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Distal radial approach versus conventional radial approach: a comparative study of feasibility and safety.

Rania Hammami, Fatma Zouari, Mohamed Aymen Ben Abdessalem, Awatef Sassi, Tarek Ellouze, Amine Bahloul, Souad Mallek, Faten Triki, Abdallah Mahdhaoui, Gouider Jeridi, Leila Abid, Selma Charfeddine, Samir Kammoun, Jihen Jdidi,

The distal radial approach (DRA) is suggested to have benefits over the conventional radial approach (CRA) in terms of local complications and comfort of both patient and operator. Therefore, we aimed to compare the feasibility and safety of DRA and CRA in a real life population. We conducted a prospective, ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2021, 16(1):1830600]

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The role of microglia versus peripheral macrophages in maladaptive plasticity after nerve injury.

Thomas A Szabo-Pardi, Nilesh M Agalave, Michael D Burton,

Neural Regen Res (Neural regeneration research)
[2021, 16(6):1202-1203]

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Current application and future directions of photobiomodulation in central nervous diseases.

Muyue Yang, Zhen Yang, Pu Wang, Zhihui Sun,

Photobiomodulation using light in the red or near-infrared region is an innovative treatment strategy for a wide range of neurological and psychological conditions. Photobiomodulation can promote neurogenesis and elicit anti-apoptotic, anti-inflammatory and antioxidative responses. Its therapeutic effects have been demonstrated in studies on neurological diseases, peripheral nerve injuries, pain relief ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(6):1177-1185]

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Prospects for the application of transcranial magnetic stimulation in diabetic neuropathy.

Xi Xu, Dong-Sheng Xu,

Encouraging results have been reported for the use of transcranial magnetic stimulation-based nerve stimulation in studies of the mechanisms of neurological regulation, nerve injury repair, and nerve localization. However, to date, there are only a few reviews on the use of transcranial magnetic stimulation for diabetic neuropathy. Patients with diabetic ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(5):955-962]

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Secondary release of the peripheral nerve with autologous fat derivates benefits for functional and sensory recovery.

Natalia E Krzesniak, Anna Sarnowska, Anna Figiel-Dabrowska, Katarzyna Osiak, Krystyna Domanska-Janik, Bartłomiej H Noszczyk,

The reconstruction of nerve continuity after traumatic nerve injury is the gold standard in hand surgery. Immediate, tension-free, end-to-end nerve suture ensures the best prognosis. The recovery is mostly promising; however, in a few cases, insufficient outcomes in motor or sensory function are observed. Intra- and extra-fascicular scarring accompanies the ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(5):856-864]

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Nerve growth factor in muscle afferent neurons of peripheral artery disease and autonomic function.

Lu Qin, Jianhua Li,

In peripheral artery disease patients, the blood supply directed to the lower limbs is reduced. This results in severe limb ischemia and thereby enhances pain sensitivity in lower limbs. The painful perception is induced and exaggerate during walking, and is relieved by rest. This symptom is termed by intermittent claudication. ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(4):694-699]

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Guanosine-5'-triphosphate cyclohydrolase 1 regulated long noncoding RNAs are potential targets for microglial activation in neuropathic pain.

Yan-Hu Liang, Guo-Wu Chen, Xue-Song Li, Shu Jia, Chun-Yang Meng,

Several studies have confirmed that microglia are involved in neuropathic pain. Inhibition of guanosine-5'-triphosphate cyclohydrolase 1 (GTPCH1) can reduce the inflammation of microglia. However, the precise mechanism by which GTPCH1 regulates neuropathic pain remains unclear. In this study, BV2 microglia were transfected with adenovirus to knockdown GTPCH1 expression. High throughput ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(3):596-600]

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Progress in clinical trials of cell transplantation for the treatment of spinal cord injury: how many questions remain unanswered?

Xu-Chang Hu, Yu-Bao Lu, Yong-Na Yang, Xue-Wen Kang, Yong-Gang Wang, Bing Ma, Shuai Xing,

Spinal cord injury can lead to severe motor, sensory and autonomic nervous dysfunctions. However, there is currently no effective treatment for spinal cord injury. Neural stem cells and progenitor cells, bone marrow mesenchymal stem cells, olfactory ensheathing cells, umbilical cord blood stem cells, adipose stem cells, hematopoietic stem cells, oligodendrocyte ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(3):405-413]

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Comparison of analgesic efficacy of acetaminophen monotherapy versus acetaminophen combinations with either pethidine or parecoxib in patients undergoing laparoscopic cholecystectomy: a randomized prospective study.

Francesk Mulita, Georgios Karpetas, Elias Liolis, Michail Vailas, Levan Tchabashvili, Ioannis Maroulis,

Aim To investigate analgesic effect of three different regimens of combination of analgesics administered to patients undergoing laparoscopic cholecystectomy. Methods Patients undergoing laparoscopic cholecystectomy were randomly allocated to one of three groups on admission, depending of a prescribed post-operative analgesic regimen. Patients allocated to the group A received a combination ... Read more >>

Med Glas (Zenica) (Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina)
[2021, 18(1):]

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Intermittent traction therapy in the treatment of chronic low back pain.

Edina Tanović, Damir Čelik, Đemil Omerović, Vanda Zovko Omeragić, Amila Jaganjac, Hadžan Konjo, Emina Rovčanin, Hana Omerović,

Aim To investigate the effect of intermittent traction therapy (ITT) on pain in patients with chronic low back pain (CLBP). Methods A total of 81 patients with CLBP were included: experimental group received ITT (n=40) and control group received conservative physical treatment (n=41) 10 times for two weeks. A visual ... Read more >>

Med Glas (Zenica) (Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina)
[2021, 18(1):]

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Comparing hand strength and quality life of locking plate versus intramedullary k wire for transverse midshaft metacarpal fractures.

Andrea Pasquino, Alessandro Tomarchio, Enio De Cruto, Jacopo Conteduca, Damiano Longo, Valentina Russi, Giuseppe Pica, Luigi Meccariello, Giuseppe Rollo,

Aim In the scientific literature there are no papers that clarify which method of surgical fixation in transverse metacarpal fractures has the best functional outcomes. The aim of this study was to compare the hand strength obtained using two different methods in the treatment of these fractures. Methods A total ... Read more >>

Med Glas (Zenica) (Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina)
[2021, 18(1):]

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Rare and uncommon diseases of the hip: arthroscopic treatment.

Christian Carulli, Alberto Schiavo, Alberto Rigon, Wondi De Marchi, Matteo Innocenti, Luigi Meccariello, Massimo Innocenti,

Aim Uncommon and rare hip diseases are sources of pain and functional limitation particularly in young patients. Some of these conditions may be nowadays treated by arthroscopy due to the expertise and technical tips that high-volume hip arthroscopies have achieved during the last decades ensuring a wider range of indications ... Read more >>

Med Glas (Zenica) (Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina)
[2021, 18(1):]

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Physical Therapy Management of Neurogenic Thoracic Outlet Syndrome.

Eileen Collins, Michael Orpin,

Neurogenic thoracic outlet syndrome is a complex and challenging condition to manage. There is a lack of high-quality evidence to guide clinical decision making and therefore a need to individualize treatment. Examination includes identifying postural, anatomic, and biomechanical factors that contribute to compromise of the neurovascular structures. Patients can experience ... Read more >>

Thorac Surg Clin (Thoracic surgery clinics)
[2021, 31(1):61-69]

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Headache in the Emergency Department: Avoiding Misdiagnosis of Dangerous Secondary Causes, An Update.

Ryan Raam, Ramin R Tabatabai,

In the initial assessment of the headache patient, the emergency physician must consider several dangerous secondary causes of headache. A thorough history and physical examination, along with consideration of a comprehensive differential diagnosis may alert the emergency physician to the diagnosis of a secondary headache particularly when the history is ... Read more >>

Emerg Med Clin North Am (Emergency medicine clinics of North America)
[2021, 39(1):67-85]

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Primary Management of Nail Bed and Fingertip Injuries in the Emergency Department.

Jessica B Hawken, Aviram M Giladi,

Appropriate management of the acute fingertip and nail bed injury is critical for optimizing patient outcomes. Mismanaged injuries can lead to chronic pain and deformity. Subungual hematomas may be treated with simple trephination for pain relief. Nail bed lacerations may be repaired using dissolvable suture or octyl-2-cyanoacrylate, and in most ... Read more >>

Hand Clin (Hand clinics)
[2021, 37(1):1-10]

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Brain plasticity after peripheral nerve injury treatment with massage therapy based on resting-state functional magnetic resonance imaging.

Xiang-Xin Xing, Mou-Xiong Zheng, Xu-Yun Hua, Shu-Jie Ma, Zhen-Zhen Ma, Jian-Guang Xu,

Massage therapy is an alternative treatment for chronic pain that is potentially related to brain plasticity. However, the underlying mechanism remains unclear. We established a peripheral nerve injury model in rats by unilateral sciatic nerve transection and direct anastomosis. The experimental rats were treated over the gastrocnemius muscle of the ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(2):388-393]

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Diverticulosis, Diverticulitis, and Diverticular Bleeding.

David Wan, Tibor Krisko,

Diverticulosis is an anatomic change in the colon that is characterized by outpouching of the mucosa and submucosa through the muscularis. Its prevalence increases with age so most of the elderly patients have this condition. Although diverticulosis is common, diverticular disease, in which there are clinical sequelae, is rare. This ... Read more >>

Clin Geriatr Med (Clinics in geriatric medicine)
[2021, 37(1):141-154]

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The Value of Photo Biological Regulation Based on Nano Semiconductor Laser Technology in the Treatment of Hypertension Fundus Disease.

Xingui Hu, Linan Zhou, Huifeng Wang, Yuanpeng Gao, Yan Gao, Christopher M Bowie, Sowmya Srinivasan,

With the development of nanometer semiconductor laser technology, due to the wide range of photobiological regulation and non-invasive advantages, it is widely used in clinical research, including reducing pain, accelerating wound healing, nerve injury repair and regeneration. Increase tissue blood flow, improve anxiety and depression, and treat Parkinson's and retinal ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2021, 21(2):1323-1330]

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Magnetic Resonance Spectroscopy Assessment of Brain Metabolite Concentrations in Individuals With Chronic Whiplash-associated Disorder: A Cross-sectional Study.

Scott F Farrell, Gary J Cowin, Ashley Pedler, Gail Durbridge, Rutger M J de Zoete, Michele Sterling,

<b>Objectives:</b>Pathophysiologic mechanisms underpinning ongoing pain in whiplash-associated disorder (WAD) are not well understood, however, alterations in brain morphology and function have been observed in this population and in other chronic pain conditions. This study investigated metabolite profiles of brain regions in people with chronic WAD compared with controls.<br><br><b>Materials and methods:</b>Thirty-eight ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(1):28-37]

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Research on the Treatment of Diabetic Foot with Ulcer Based on Nano-Silver Antibacterial Dressing.

Lumeng Yang, Fang Liu, Yijun Chen, Zhangyi Liu, Guowu Zhang, Mohamadreza Najiminaini, Tadashi Matsunaga,

The incidence of diabetes has been increasing year by year. Long-term growth in blood sugar causes complications such as diabetic foot ulcer and infections, which will increase the difficulty of ulcer treatment. The diabetes brings great pain and heavy economic burden to patients and their families. In view of the ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2021, 21(2):1220-1229]

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Toward Understanding Movement-evoked Pain (MEP) and its Measurement: A Scoping Review.

Dottington Fullwood, Sydney Means, Ericka N Merriwether, Ruth L Chimenti, Simar Ahluwalia, Staja Q Booker,

<b>Objective:</b>Individuals with chronic pain conditions often report movement as exacerbating pain. An increasing number of researchers and clinicians have recognized the importance of measuring and distinguishing between movement-evoked pain (MEP) and pain at rest as an outcome. This scoping review maps the literature and describes MEP measurement techniques.<br><br><b>Materials and methods:</b>The ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(1):61-78]

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Pharmacological Manipulation of Translation as a Therapeutic Target for Chronic Pain.

Muhammad Saad Yousuf, Stephanie I Shiers, James J Sahn, Theodore J Price,

Dysfunction in regulation of mRNA translation is an increasingly recognized characteristic of many diseases and disorders, including cancer, diabetes, autoimmunity, neurodegeneration, and chronic pain. Approximately 50 million adults in the United States experience chronic pain. This economic burden is greater than annual costs associated with heart disease, cancer, and diabetes ... Read more >>

Pharmacol Rev (Pharmacological reviews)
[2021, 73(1):59-88]

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