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Continuous renal replacement therapy in patients with HIV/AIDS.

Hebing Guo, Jingyuan Liu, Lin Pu, Jingjing Hao, Ningning Yin, Yufeng Liu, Haofeng Xiong, Ang Li,

BACKGROUND:Acute kidney injury (AKI) is a common complication among human immunodeficiency virus (HIV)-infected patients resulting in increased morbidity and mortality. Continuous renal replacement therapy (CRRT) is a useful method and instrument in critically ill patients with fluid overload and metabolic disarray, especially in those who are unable to tolerate the ... Read more >>

BMC Nephrol (BMC nephrology)
[2020, 21(1):95]

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Comparing passive dosing and solvent spiking methods to determine the acute toxic effect of pentachlorophenol on Daphnia magna.

Hyun-Ah Kwon, Yoonah Jeong, Hyun Pyo Jeon, Sanghun Kim,

Pentachlorophenol (PCP) is a widespread and persistent hydrophobic organic pollutant in the environment despite its restricted public use. Risk assessment of such hydrophobic organic compounds (HOCs) is challenging because sorption and volatilization issues during toxicity test often lead to inconsistent exposure concentration. Considering the hydrophobicity of the PCP, in this ... Read more >>

Ecotoxicology (Ecotoxicology (London, England))
[2020, :]

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Protective effect of catechin on pentachlorophenol-induced cytotoxicity and genotoxicity in isolated human blood cells.

Nikhil Maheshwari, Riaz Mahmood,

Pentachlorophenol (PCP) is an organochlorine compound that is used as pesticide, biocide, and wood preservative. PCP is highly toxic and carcinogenic. It has been detected in food and several consumable products. The toxicity of PCP is thought to be due to generation of oxidative stress in cells. We examined whether ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2020, :]

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MEMS biosensor for monitoring water toxicity based on quartz crystal microbalance.

Kun-Lin Lee, Simon Ng, Fang Li, Anis Nurashikin Nordin, Ioana Voiculescu,

This paper presents the use of a commercial quartz crystal microbalance (QCM) to investigate live-cell activity in water-based toxic solutions. The QCM used in this research has a resonant frequency of 10 MHz and consists of an AT-cut quartz crystal with gold electrodes on both sides. This QCM was transformed into ... Read more >>

Biointerphases (Biointerphases)
[2020, 15(2):021006]

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"Better be awake"-a role for awake extracorporeal membrane oxygenation in acute respiratory distress syndrome due to Pneumocystis pneumonia.

Klaus Stahl, Benjamin Seeliger, Marius M Hoeper, Sascha David,

Crit Care (Critical care (London, England))
[2019, 23(1):418]

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Management of HIV-infected patients in the intensive care unit.

François Barbier, Mervin Mer, Piotr Szychowiak, Robert F Miller, Éric Mariotte, Lionel Galicier, Lila Bouadma, Pierre Tattevin, Élie Azoulay,

The widespread use of combination antiretroviral therapies (cART) has converted the prognosis of HIV infection from a rapidly progressive and ultimately fatal disease to a chronic condition with limited impact on life expectancy. Yet, HIV-infected patients remain at high risk for critical illness due to the occurrence of severe opportunistic ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(2):329-342]

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Biochar enhances bioelectrochemical remediation of pentachlorophenol-contaminated soils via long-distance electron transfer.

Xixi Cai, Yong Yuan, Linpeng Yu, Beiping Zhang, Jibing Li, Ting Liu, Zhen Yu, Shungui Zhou,

The soil bioelectrochemical system (SBES) is a promising biotechnology for the remediation of contaminated soils. However, the effective distance of pollutant removal in the SBES was usually limited in a few centimeters near the electrode surface. In this study, we used biochar as the model conductor to construct a conductive ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 391:122213]

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Intoxication with 3-MeO-PCP alone: A case report and literature review.

Antoine Berar, Jean-Sébastien Allain, Sophie Allard, Charles Lefevre, Alain Baert, Isabelle Morel, Renaud Bouvet, Thomas Gicquel,

RATIONALE:3-Methoxyphencyclidine (3-MeO-PCP) is a new psychoactive substance derived from phencyclidine. Although it can lead to severe intoxications, the main manifestations and optimal management have not been well characterized. Here, we report 2 cases of 3-MeO-PCP intoxication in the same patient, and summarize the manifestations of this intoxication reported in literature. ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(52):e18295]

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An overview of Pneumocystis jirovecii pneumonia for the African generalist practitioner.

I Govender, O M Maphasha, S Rangiah, C Steyn,

Introduction:Pneumocystis jirovecii is the causative organism of Pneumocystis pneumonia (PCP) in humans, which is more common among immunocompromised patients. Classically patients present with fever, non-productive cough, and dyspnoea. In the HIV-infected individuals the symptoms may be subtle at first, but gradually progress over several weeks. In the HIV-uninfected patient, however, ... Read more >>

Afr Health Sci (African health sciences)
[2019, 19(4):3200-3207]

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Investigation of finishing of leather for inside parts of the shoes with a natural biocide.

Elżbieta Bielak, Ewa Marcinkowska, Justyna Syguła-Cholewińska,

The prevention of decrease of quality caused by microbial activity in footwear materials entails the use of biocides. However, these substances may pose a hazard to humans and to the natural environment. The paper presents the results of antimicrobial effect investigation for cowhide leather treated with oregano oil. In these ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):3467]

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Chloroanisoles and Chlorophenols Explain Mold Odor but Their Impact on the Swedish Population Is Attributed to Dampness and Mold.

Johnny C Lorentzen, Stephanie A Juran, Lena Ernstgård, Mats J Olsson, Gunnar Johanson,

We recently reported that mold odor may be explained by chloroanisoles (CAs) formed by microbial biotransformation of chlorophenols (CPs) in legacy wood preservatives. Here we examine psychophysical aspects of CAs and trace their historic origins in buildings. Our exposure of healthy volunteers shows that 2,4,6-triCA is often perceived as unpleasant, ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(3):]

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Continuous Renal Replacement Therapy in patients with HIV/AIDS

Ang Li, Hebing Guo, Jingyuan Liu, Lin Pu, Jingjing Hao, Ningning Yin, Yufeng Liu, Haofeng Xiong,

<title>Abstract</title> <p> Background: Acute kidney injury (AKI) is a common complication among human immunodeficiency virus (HIV)-infected patients resulting in increased morbidity and mortality. Continuous renal replacement therapy (CRRT) is a useful method and instrument in critically ill patients with fluid overload and metabolic disarray, especially in those who ... Read more >>

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Building a comprehensive cancer survivorship program.

Tessa Flores, Kathryn M Glaser, Douglas McDaniel, Denise Rokitka, Katharine A Amato, Mary E Reid,

There is a significant increase in the number of people surviving cancer as a result of improved detection and better treatments. In the United States (US) alone, these numbers are estimated to reach 20 million by 2026 [Miller et al (2016) CA Cancer J Clin 66(4) 271-289)]; [Bluethmann et al ... Read more >>

Ecancermedicalscience (Ecancermedicalscience)
[2019, 13:992]

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Maize straw biochar addition inhibited pentachlorophenol dechlorination by strengthening the predominant soil reduction processes in flooded soil.

Min Zhu, Xiaofei Lv, Ashley E Franks, Philip C Brookes, Jianming Xu, Yan He,

Biochar has received increasing attention for its multifunctional applications as a soil amendment. The dual effect of biochar on reductive organic pollutants and soil biogeochemical processes under anaerobic environments in parallel has yet to be fully explored. In this study, anaerobic batch experiments were conducted to examine the effect of ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 386:122002]

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Standardized warfarin monitoring decreases adverse drug reactions.

Lisa B E Shields, Paula Fowler, Diane M Siemens, Douglas J Lorenz, Kenneth C Wilson, Steven T Hester, Joshua T Honaker,

BACKGROUND:While warfarin is the most commonly prescribed medication to prevent thromboembolic disorders, the risk of adverse drug reactions (ADR) poses a serious concern. This prospective study evaluated how primary care providers (PCP) and cardiologists at our Institution managed patients treated with warfarin with the goal of decreasing the number of ... Read more >>

BMC Fam Pract (BMC family practice)
[2019, 20(1):151]

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Phencyclidine: A Rare Cause of Saccadic Intrusions.

M N Shameer Nijam, Narmathey Thambirajah, Dhanushka Vithanawasam, Kumarangie Vithanage, Damith S Liyanage, I Kishara Gooneratne, Sunethra Senanayake,

Saccadic intrusions such as opsoclonus and ocular flutter are often due to a paraneoplastic or a parainfectious condition. Toxins/drugs may rarely cause them. Herein, we report a rare case of ocular flutter/opsoclonus due to phencyclidine (PCP) toxicity. Our patient is a 21-year-old male who presented with a 3-day history of ... Read more >>

Ann Indian Acad Neurol (Annals of Indian Academy of Neurology)
[2019, 22(4):503-505]

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Opportunistic infections after conversion to belatacept in kidney transplantation.

Dominique Bertrand, Nathalie Chavarot, Philippe Gatault, Cyril Garrouste, Nicolas Bouvier, Anne Grall-Jezequel, Maïté Jaureguy, Sophie Caillard, Mathilde Lemoine, Charlotte Colosio, Léonard Golbin, Jean-Philippe Rerolle, Antoine Thierry, Johnny Sayegh, Isabelle Etienne, Ludivine Lebourg, Rebecca Sberro, Dominique Guerrot,

BACKGROUND:Belatacept (bela) rescue therapy seems to be a valuable option for calcineurin inhibitor chronic toxicity in kidney transplantation. Nevertheless, the risk of infection associated with bela is not well reported. METHODS:We report the rate of opportunistic infections (OPI) after a switch to bela in a multicentric cohort of 280 kidney ... Read more >>

Nephrol. Dial. Transplant. (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2020, 35(2):336-345]

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The Broad Clinical Spectrum of Disseminated Histoplasmosis in HIV-Infected Patients: A 30 Years' Experience in French Guiana.

Pierre Couppié, Katarina Herceg, Morgane Bourne-Watrin, Vincent Thomas, Denis Blanchet, Kinan Drak Alsibai, Dominique Louvel, Felix Djossou, Magalie Demar, Romain Blaizot, Antoine Adenis,

Histoplasmosis is a common but neglected AIDS-defining condition in endemic areas for Histoplasma capsulatum. At the advanced stage of HIV infection, the broad spectrum of clinical features may mimic other frequent opportunistic infections such as tuberculosis and makes it difficult for clinicians to diagnose histoplasmosis in a timely manner. Diagnosis ... Read more >>

J Fungi (Basel) (Journal of fungi (Basel, Switzerland))
[2019, 5(4):]

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Dynamic processes in conjunction with microbial response to disclose the biochar effect on pentachlorophenol degradation under both aerobic and anaerobic conditions.

Yan Xu, Jiaqi Liu, Wenshan Cai, Jiayin Feng, Zhijiang Lu, Haizhen Wang, Ashley E Franks, Caixian Tang, Yan He, Jianming Xu,

Organochlorines are critical soil contaminants and the use of biochar has recently shown potential to improve soil remediation. However, little is known about biochar-microbe interactions nor the impact on environmental processes such as the immobilization and biodegradation of organochlorine compounds. In this study, we performed microcosm experiments to elucidate how ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 384:121503]

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Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study).

Guido Schäfer, Christian Hoffmann, Keikawus Arasteh, Dirk Schürmann, Christoph Stephan, Björn Jensen, Matthias Stoll, Johannes R Bogner, Gerd Faetkenheuer, Jürgen Rockstroh, Hartwig Klinker, Georg Härter, Albrecht Stöhr, Olaf Degen, Eric Freiwald, Anja Hüfner, Sabine Jordan, Julian Schulze Zur Wiesch, Marylyn Addo, Ansgar W Lohse, Jan van Lunzen, Stefan Schmiedel, ,

BACKGROUND:To evaluate clinical outcomes after either immediate or deferred initiation of antiretroviral therapy in HIV-1-infected patients, presenting late with pneumocystis pneumonia (PCP) or toxoplasma encephalitis (TE). METHODS:Phase IV, multicenter, prospective, randomized open-label clinical trial. Patients were randomized into an immediate therapy arm (starting antiretroviral therapy (ART) within 7 days after initiation ... Read more >>

AIDS Res Ther (AIDS research and therapy)
[2019, 16(1):34]

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Use of glucocorticoids in the critical care setting: Science and clinical evidence.

Edward D Chan, Michael M Chan, Mallory M Chan, Paul E Marik,

Glucocorticoids (GC) in all its various forms and formulations are likely one of the most commonly used pharmacologic agents in medicine. Their use can be profoundly therapeutic but are also associated with a myriad of acute and chronic side effects. It is fairly well-accepted in the medical community that GC ... Read more >>

Pharmacol. Ther. (Pharmacology & therapeutics)
[2020, 206:107428]

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Pentachlorophenol removal from aqueous solutions using Montmorillonite modified by Silane & Imidazole: kinetic and isotherm study.

Zahra Seyedi, Ali Akbar Amooey, Abdoliman Amouei, Hamed Tashakkorian,

Background:Removal of pentachlorophenol (PCP) from wastewater containing chlorophenols, due to its toxicity, mutagenic and carcinogenic properties, has been attracted much interests of researchers. Methods:In this research, K10 montmorillonite was modified by silane and imidazole (Im) for increasing the removal percentage of PCP from aqueous solutions. It was characterized by FTIR, ... Read more >>

J Environ Health Sci Eng (Journal of environmental health science & engineering)
[2019, 17(2):989-999]

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Bacterial networks mediate pentachlorophenol dechlorination across land-use types with citrate addition.

Hui Li, Yuji Jiang, Shanli Wang, Lijun Chen, Xiaocui Wen, Minxue Huang, Xiaocui Cheng, Zhongliang Cheng, Liang Tao,

Soil microorganisms play a crucial role in the bioremediation of pentachlorophenol (PCP)-contaminated soils. However, whether and how soil bacterial networks with keystone taxa affect PCP dechlorination is not well understood. The present study investigated the effects of citrate on soil bacterial networks mediating PCP dechlorination by direct and indirect transformation ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 384:121295]

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Clinical Characteristics of Pneumocystis Pneumonia After Parental Renal Transplantation.

Tiantian Li, Junqin Shi, Fei Xu, Xiaoling Xu,

Purpose:To analyze the clinical characteristics of Pneumocystis pneumonia (PCP) in renal transplant recipients, identify early sensitivity indicators, and optimize clinical strategies. Patients and Methods:We retrospectively analyzed clinical data for 24 patients with confirmed PCP who underwent renal transplantation (RT) between 2010 and 2019, encompassing a mean follow-up of 29 (range, ... Read more >>

Infect Drug Resist (Infection and drug resistance)
[2020, 13:81-88]

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Toxicity assessment of parabens in Caenorhabditis elegans.

Yogendra Nagar, Ravindra Singh Thakur, Tuba Parveen, Devendra Kumar Patel, Kristipati Ravi Ram, Aruna Satish,

Parabens, the alkyl esters of p-hydroxybenzoic acid such as methylparaben (MeP), ethylparaben (EtP), propylparaben (PrP), butylparaben (BuP) are used as a preservative in food, personal care products (PCPs), and pharmaceuticals, due to their antimicrobial properties. Parabens are continuously released into the environment, during washout of PCPs, disposal of industrial waste ... Read more >>

Chemosphere (Chemosphere)
[2020, 246:125730]

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