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Combination of chemotherapy and immune checkpoint therapy by the immunoconjugates-based nanocomplexes synergistically improves therapeutic efficacy in SCLC.

Zhang Tao, Xingwang Kuai, Guangwei Wang, Sanfeng Liu, Kai Liu, Heng Zhang, Shujing Xia, Hua Zhu,

Although the etoposide and carboplatin (EP) combination strategy has been the first-line chemotherapy, patients with extensive-stage disease small-cell lung cancer (SCLC) still have poor survival outcomes. Our retrospective analysis revealed that 46 patients with SCLC only achieved medium overall survival (OS) of 11.6 months after treated by EP. Recently, it was ... Read more >>

Drug Deliv (Drug delivery)
[2022, 29(1):1571-1581]

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Optimal definitions for computing HKA angle in caos: an in-vitro comparison study.

Guillaume Dardenne, Bhushan Borotikar, Hoel Letissier, Ahmed Zemirline, Eric Stindel,

The goal of this study was to assess and compare the precision and accuracy of nine and seven methods usually used in Computer Assisted Orthopedic Surgery (CAOS) to estimate respectively the Knee Center (KC) and the Frontal Plane (FP) for the determination of the HKA angle (HKAA). An in-vitro experiment ... Read more >>

Comput Assist Surg (Abingdon) (Computer assisted surgery (Abingdon, England))
[2022, 27(1):27-34]

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