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Normal Sleep Sleep Physiology and Sleep Deprivation

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Insights from human sleep research on neural mechanisms of Alzheimer's disease.

Susanna Cordone, Luigi De Gennaro,

Neural Regen Res (Neural regeneration research)
[2020, 15(7):1251-1252]

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Sleep Deprivation: Cytokine and Neuroendocrine Effects on Perception of Effort.

Tom Cullen, Gavin Thomas, Alex J Wadley,

INTRODUCTION:An increased perception of effort and subjective fatigue are thought to be central to decreased exercise performance observed after disrupted sleep. However, there is limited understanding of mechanisms that underpin these phenomena. We investigated the role of interleukin-6 (IL-6), the soluble IL-6 receptor, and neuroendocrine factors (cortisol, adrenaline, noradrenaline, and ... Read more >>

Med Sci Sports Exerc (Medicine and science in sports and exercise)
[2020, 52(4):909-918]

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Sleep and Reproductive Health.

Olubodun Michael Lateef, Michael Olawale Akintubosun,

The reproductive function of humans is regulated by several sex hormones which are secreted in synergy with the circadian timing of the body. Sleep patterns produce generic signatures that physiologically drive the synthesis, secretion, and metabolism of hormones necessary for reproduction. Sleep deprivation among men and women is increasingly reported ... Read more >>

J Circadian Rhythms (Journal of Circadian Rhythms)
[2020, 18:]

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Antidepressant effect of Gentiana olivieri Griseb. in male rats exposed to chronic mild stress.

Ahmet Berk, İsmet Yılmaz, Nurettin Abacıoğlu, Mustafa Bahadır Kaymaz, Merve Gökşin Karaaslan, Ebru Kuyumcu Savan,

Background: The flowering parts of Gentiana olivieri, known as 'Afat' in the southeastern Anatolia region of Turkey, are used as a tonic, an appetizer, and for the treatment of several mental disorders, including depression. The purpose of this study is to investigate the antidepressant effect of G. olivieri ethanol extract ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2020, 15(1):1725991]

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Effect of Angle of View and Partial Sleep Deprivation on Distance Perception.

Hamza Baati, Hamdi Chtourou, Wassim Moalla, Mohamed Jarraya, Pantelis T Nikolaidis, Thomas Rosemann, Beat Knechtle,

The present study aimed to investigate the effects of intensive effort on egocentric distance perception according to different angles of view after sleep deprivation at the beginning (SDB) or at the end (SDE) of the night and after a normal sleep night (NNS). Ten male students soccer players (age 22.8 ... Read more >>

Front Psychol (Frontiers in Psychology)
[2020, 11:201]

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The Links Between the Gut Microbiome, Aging, Modern Lifestyle and Alzheimer's Disease.

Sholpan Askarova, Bauyrzhan Umbayev, Abdul-Razak Masoud, Aiym Kaiyrlykyzy, Yuliya Safarova, Andrey Tsoy, Farkhad Olzhayev, Almagul Kushugulova,

Gut microbiome is a community of microorganisms in the gastrointestinal tract. These bacteria have a tremendous impact on the human physiology in healthy individuals and during an illness. Intestinal microbiome can influence one's health either directly by secreting biologically active substances such as vitamins, essential amino acids, lipids et cetera ... Read more >>

Front Cell Infect Microbiol (Frontiers in cellular and infection microbiology)
[2020, 10:]

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Drosophila insulin-like peptide 2 mediates dietary regulation of sleep intensity.

Elizabeth B Brown, Kreesha D Shah, Richard Faville, Benjamin Kottler, Alex C Keene,

Sleep is a nearly universal behavior that is regulated by diverse environmental stimuli and physiological states. A defining feature of sleep is a homeostatic rebound following deprivation, where animals compensate for lost sleep by increasing sleep duration and/or sleep depth. The fruit fly, Drosophila melanogaster, exhibits robust recovery sleep following ... Read more >>

PLoS Genet. (PLoS genetics)
[2020, 16(3):e1008270]

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Editorial: Metabolic Health in Normal and Abnormal Sleep.

David Kim, Camilla Miranda Hoyos, Babak Mokhlesi, Sushmita Pamidi, Jonathan C Jun,

Front Endocrinol (Lausanne) (Frontiers in Endocrinology)
[2020, 11:131]

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Age effect on gray matter volume changes after sleep restriction.

Zhiliang Long, Fei Cheng, Xu Lei,

Sleep deprivation disrupted functional and structural brain areas which are associated with cognition and emotion in healthy participants. However, the effect of age on the structural changes after sleep restriction remains unclear. In the current study, gray matter volume was calculated in 43 young adults and 37 old adults before ... Read more >>

PLoS ONE (PloS one)
[2020, 15(2):e0228473]

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Sleepiness and injury risk in emergency medical service workers in Taiwan.

Ming-Hung Lin, Yin-Chun Huang, Wei-Kung Chen, Jong-Yi Wang,

BACKGROUND:Insufficient sleep is a common health and safety risk factor in high-impact workplaces where workers are required to take rotating shifts. However, studies on sleepiness-related risks and incidents, particularly among emergency medical services (EMS) workers are limited. OBJECTIVE:This study sought to investigate the prevalence of sleepiness and related workplace incidents ... Read more >>

PLoS ONE (PloS one)
[2020, 15(2):e0229202]

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Is Sleep Disruption a Cause or Consequence of Alzheimer's Disease? Reviewing Its Possible Role as a Biomarker.

Maria-Angeles Lloret, Ana Cervera-Ferri, Mariana Nepomuceno, Paloma Monllor, Daniel Esteve, Ana Lloret,

In recent years, the idea that sleep is critical for cognitive processing has gained strength. Alzheimer's disease (AD) is the most common form of dementia worldwide and presents a high prevalence of sleep disturbances. However, it is difficult to establish causal relations, since a vicious circle emerges between different aspects ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(3):]

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Steps Towards Developing Effective Treatments for Neuropsychiatric Disturbances in Alzheimer's Disease: Insights From Preclinical Models, Clinical Data, and Future Directions.

Amalie Clement, Ove Wiborg, Ayodeji A Asuni,

Alzheimer's disease (AD) is the most common form of dementia worldwide. It is mostly known for its devastating effect on memory and learning but behavioral alterations commonly known as neuropsychiatric disturbances (NPDs) are also characteristics of the disease. These include apathy, depression-like behavior, and sleep disturbances, and they all contribute ... Read more >>

Front Aging Neurosci (Frontiers in Aging Neuroscience)
[2020, 12:56]

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The Impact of Shift-Work and Night Shift-Work on Thyroid: A Systematic Review.

Veruscka Leso, Ilaria Vetrani, Alessandra Sicignano, Rosaria Romano, Ivo Iavicoli,

Thyroid hormones are regulated by the pituitary thyroid stimulating hormone (TSH), whose secretion presents a circadian rhythmicity. Indeed, it is conceivable that shift- and night shift-work, affecting sleep-wake rhythms, may impact thyroid functionality. Therefore, the aim of the present review was to provide an overview on the association between shift- ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(5):]

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The future of sleep health: a data-driven revolution in sleep science and medicine.

Ignacio Perez-Pozuelo, Bing Zhai, Joao Palotti, Raghvendra Mall, Michaël Aupetit, Juan M Garcia-Gomez, Shahrad Taheri, Yu Guan, Luis Fernandez-Luque,

In recent years, there has been a significant expansion in the development and use of multi-modal sensors and technologies to monitor physical activity, sleep and circadian rhythms. These developments make accurate sleep monitoring at scale a possibility for the first time. Vast amounts of multi-sensor data are being generated with ... Read more >>

NPJ Digit Med (NPJ digital medicine)
[2020, 3:42]

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Effect of Heart Rate Variability Biofeedback Sessions With Resonant Frequency Breathing on Sleep: A Pilot Study Among Family Caregivers of Patients With Cancer.

Hideaki Hasuo, Kenji Kanbara, Mikihiko Fukunaga,

Heart rate variability biofeedback (HRV-BF) is used as a skill in psychosomatic medicine, but is not yet established in the field of sleep. The present study aimed to evaluate the effect of HRV-BF with resonant frequency breathing (RFB) on sleep performed once every 2 weeks and the usefulness of practice ... Read more >>

Front Med (Lausanne) (Frontiers in Medicine)
[2020, 7:61]

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Changing the Tone of Clinical Study Design in the Cannabis Industry.

Joseph M Antony, Alison C McDonald, Farshid Noorbhaksh, Najla Guthrie, Mal Evans,

Cannabis (also known as marijuana) is the most frequently used psychoactive substance globally. Cannabis exerts therapeutic functions for many indications and has vast potential as a health and wellness product. Advances in our understanding of the composition and pharmacological properties of cannabis have revealed interactions between cannabis, an individuals' circadian ... Read more >>

Transl Neurosci (Translational neuroscience)
[2020, 11:4-9]

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Sleep duration is associated with vitamin D deficiency in older women living in Macao, China: A pilot cross-sectional study.

Xiaoying Liu, Liang Ke, Jacky Ho, Myriam Abboud, Elias Mpofu, Tara C Brennan-Speranza, Rebecca S Mason, Kaye E Brock,

Chinese women are known to have both a high prevalence of metabolic syndrome (MetS) and vitamin D deficiency (serum 25-hydroxyvitamin D (25OHD) <50 nmol/l). Associations between sleep duration and circulating 25OHD have recently been reported but, to our knowledge, these associations have not been studied in older Chinese populations. We ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0229642]

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The prevalence of insomnia and restless legs syndrome among Japanese outpatients with rheumatic disease: A cross-sectional study.

Kayoko Urashima, Kunihiro Ichinose, Hideaki Kondo, Takahiro Maeda, Atsushi Kawakami, Hiroki Ozawa,

The prevalence of symptomatic insomnia and the prevalence of restless legs syndrome (RLS) are known to be higher among patients with rheumatic diseases compared to the general population. The prevalences of insomnia and RLS reported in a questionnaire by Japanese patients with rheumatic diseases at an outpatient clinic were analyzed ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0230273]

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Improved Physical Performance and Decreased Muscular and Oxidative Damage With Postlunch Napping After Partial Sleep Deprivation in Athletes.

Mohamed Romdhani, Nizar Souissi, Yassine Chaabouni, Kacem Mahdouani, Tarak Driss, Karim Chamari, Omar Hammouda,

PURPOSE:To investigate the effects of napping after partial sleep deprivation (PSD) on reaction time, mood, and biochemical response to repeated-sprint exercise in athletes. METHODS:Nine male judokas performed 4 test sessions in a counterbalanced and randomized order. Participants accomplished 1 control session after a normal sleep night (NSN) and 3 after ... Read more >>

Int J Sports Physiol Perform (International journal of sports physiology and performance)
[2020, :1-10]

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SWS Brain-Wave Music May Improve the Quality of Sleep: An EEG Study.

Dongrui Gao, Siyu Long, Hua Yang, Yibo Cheng, Sijia Guo, Yue Yu, Tiejun Liu, Li Dong, Jing Lu, Dezhong Yao,

Aim:This study investigated the neural mechanisms of brain-wave music on sleep quality. Background:Sleep disorders are a common health problem in our society and may result in fatigue, depression, and problems in daytime functioning. Previous studies have shown that brain-wave music generated from electroencephalography (EEG) signals could emotionally affect our nervous ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2020, 14:67]

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Role of biological rhythm dysfunction in the development and management of bipolar disorders: a review.

Yiming Chen, Wu Hong, Yiru Fang,

Disturbance of biological rhythms contributes to the onset of bipolar disorders and is an important clinical feature of the condition. To further explore the role of biological rhythms in bipolar disorders, 95 English articles published between 1968 and 2019 were retrieved from the PubMed database and analysed. We herein review ... Read more >>

Gen Psychiatr (General psychiatry)
[2020, 33(1):e100127]

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Attenuation of sleep deprivation dependent deterioration in male fertility parameters by vitamin C.

Nermin I Rizk, Mohamed S Rizk, Asmaa S Mohamed, Yahya M Naguib,

PURPOSE:Male fertility is multifaceted and its integrity is as well multifactorial. Normal spermatogenesis is dependent on competent testicular function; namely normal anatomy, histology, physiology and hormonal regulation. Lifestyle stressors, including sleep interruption and even deprivation, have been shown to seriously impact male fertility. We studied here both the effects and ... Read more >>

Reprod. Biol. Endocrinol. (Reproductive biology and endocrinology : RB&E)
[2020, 18(1):2]

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Neuroinflammation in Bipolar Depression.

Francesco Benedetti, Veronica Aggio, Maria Luisa Pratesi, Giacomo Greco, Roberto Furlan,

Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders. Pathological mechanisms are still vastly unclear, and current treatments with conventional medications are often unsatisfactory in maintaining symptoms control and an adequate quality of life. Consequently, current research is focusing on shedding new light on disease pathogenesis, ... Read more >>

Front Psychiatry (Frontiers in Psychiatry)
[2020, 11:71]

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An Overview on the Associations between Health Behaviors and Brain Health in Children and Adolescents with Special Reference to Diet Quality.

Sehrish Naveed, Timo Lakka, Eero A Haapala,

Unhealthy diet has been associated with overweight, obesity, increased cardiometabolic risk, and recently, to impaired cognition and academic performance. The aim of this review is to provide an overview of the associations between health behaviors and cognition and academic achievement in children and adolescents under 18 years of age with ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(3):]

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Excessive Daytime Sleepiness Measurements in Children With Attention Deficit Hyperactivity Disorder.

Stéphanie Bioulac, Jacques Taillard, Pierre Philip, Patricia Sagaspe,

Attention deficit hyperactivity disorder (ADHD) is the most commonly diagnosed neurodevelopmental disorder in childhood. It is a heterogeneous disorder in terms of clinical presentation that is probably due to the frequent occurrence of comorbidity. Children with ADHD more frequently report sleep disorders (notably delayed sleep phase syndrome) and excessive daytime ... Read more >>

Front Psychiatry (Frontiers in psychiatry)
[2020, 11:3]

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