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Full Text Journal Articles about
Nonidiopathic Pulmonary Hypertension


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Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.

Felix Chua, Sujal R Desai, Andrew G Nicholson, Anand Devaraj, Elisabetta Renzoni, Alexandra Rice, Athol U Wells,

Pleuroparenchymal fibroelastosis (PPFE) is an unusual pulmonary disease with unique clinical, radiological, and pathological characteristics. Designated a rare idiopathic interstitial pneumonia in 2013, its name refers to a combination of fibrosis involving the visceral pleura and fibroelastotic changes predominating in the subpleural lung parenchyma. Although a number of disease associations ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2019, 16(11):1351-1359]

Cited: 0 times

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Association between a Single Nucleotide Polymorphism in the 3'-UTR of ARHGEF18 and the Risk of Nonidiopathic Pulmonary Arterial Hypertension in Chinese Population.

Ding Li, Yan Sun, Xiaochao Kong, Changxing Luan, Youjia Yu, Feng Chen, Peng Chen,

ARHGEF18 has been identified as upregulated in the lung tissues of rat models of pulmonary artery hypertension introduced by hypoxia or monocrotaline (MCT). We used online SNP function prediction tools to screen the candidate SNPs that might be associated with the regulation of the ARHGEF18 expression. The result suggested that ... Read more >>

Dis. Markers (Disease markers)
[2018, 2018:2461845]

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Twelve-Year Survival in a Patient With Systemic Sclerosis-Associated Pulmonary Arterial Hypertension on Nifedipine Monotherapy.

Scott A Helgeson, Cher Y Enderby, John E Moss, Jennifer M Gass, Tonya K Zeiger, Charles D Burger,

Pulmonary arterial hypertension is a progressive vascular disease with a high mortality rate without proper therapy. Identification of the appropriate treatment for each patient is critical in regard to adverse effects, health care costs, ease of treatment, and the potential for prognostication. Treatment strategies typically begin with acute vasoreactivity testing, ... Read more >>

Mayo Clin Proc Innov Qual Outcomes (Mayo Clinic proceedings. Innovations, quality & outcomes)
[2019, 3(3):376-379]

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A Case of Warm Autoimmune Hemolytic Anemia and a Pulmonary Embolus in a Patient Treated with Triple Therapy.

Gurchetan Randhawa, Chia-Yu Chiu, Thanunthorn Suban Na Ayutthaya,

Autoimmune hemolytic anemia (AIHA) can be caused by a variety of etiologies. AIHA is associated with the development of coagulopathy, leading to potentially fatal pulmonary emboli. Here, we present a case of a 66-year-old female with a past medical history of non-Hodgkin's lymphoma and gastritis treated with triple therapy that ... Read more >>

Case Rep Hematol (Case reports in hematology)
[2019, 2019:2564682]

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Intratympanic dexamethasone for managing pregnant women with sudden hearing loss.

Yaoyao Fu, Jianghua Jing, Tongli Ren, Hui Zhao,

OBJECTIVE:This study aimed to investigate the effect and safety of intratympanic dexamethasone in pregnant women with idiopathic sudden sensorineural hearing loss (ISSNHL). METHODS:We performed a prospective study on pregnant women who suffered from ISSNHL and were treated in our clinic during 2016. The patients received intratympanic treatment three to four ... Read more >>

J. Int. Med. Res. (The Journal of international medical research)
[2019, 47(1):377-382]

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Predictors of Postoperative Ventilation in Scoliosis Surgery: A Retrospective Analysis.

Eldo Issac, Gokuldas Menon, Bindu K Vasu, Mathew George, Anu Vasudevan,

Patients undergoing corrective surgery for scoliosis may require postoperative ventilation for various reasons.The aim was to study the correlation of preoperative (pulmonary function test [PFT], etiology, and Cobb's angle) and intraoperative factors (type of surgery, number of spinal segments involved, blood transfusion, and temperature at the end of surgery) on ... Read more >>

Anesth Essays Res (Anesthesia, essays and researches)
[2018, 12(2):407-411]

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Erythropoietin upregulation in pulmonary arterial hypertension.

Vanesa A Karamanian, Michael Harhay, Gregory R Grant, Harold I Palevsky, William E Grizzle, Roham T Zamanian, Kaori Ihida-Stansbury, Darren B Taichman, Steven M Kawut, Peter L Jones,

The pathophysiologic alterations of patients with pulmonary arterial hypertension (PAH) are diverse. We aimed to determine novel pathogenic pathways from circulating proteins in patients with PAH. Multianalyte profiling (MAP) was used to measure 90 specifically selected antigens in the plasma of 113 PAH patients and 51 control patients. Erythropoietin (EPO) ... Read more >>

Pulm Circ (Pulmonary circulation)
[2014, 4(2):269-279]

Cited: 10 times

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Factors associated with the 6-minute walk distance in patients with systemic sclerosis.

Sébastien Sanges, Jonathan Giovannelli, Vincent Sobanski, Sandrine Morell-Dubois, Hélène Maillard, Marc Lambert, Céline Podevin, Nicolas Lamblin, Pascal De Groote, Jean-François Bervar, Thierry Perez, Régis Matran, Martine Rémy-Jardin, Pierre-Yves Hatron, Éric Hachulla, David Launay,

There is an ongoing debate regarding the relevance of the 6-minute walking distance (6MWD) in systemic sclerosis (SSc) assessment, widely used as a usual test in these patients as well as an outcome measure in clinical trials. In this work, we aimed to assess the associations between the 6MWD and ... Read more >>

Arthritis Res. Ther. (Arthritis Research & Therapy)
[2017, 19(1):279]

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Idiopathic noncirrhotic portal hypertension: What is it?

Guadalupe Garcia-Tsao,

Clin Liver Dis (Hoboken) (Clinical liver disease)
[2015, 5(5):120-122]

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Hormone Therapy Use and Risk of Chronic Disease in the Nurses' Health Study: A Comparative Analysis With the Women's Health Initiative.

Shilpa N Bhupathiraju, Francine Grodstein, Bernard A Rosner, Meir J Stampfer, Frank B Hu, Walter C Willett, JoAnn E Manson,

Observational studies and randomized controlled trials of menopausal hormone therapy (HT) and chronic disease risk appear to have divergent results for cardiovascular disease. However, differences may be related to a modifying effect of age, time since menopause, and HT formulation. In the Nurses' Health Study (NHS) (enrolling during 1980-1994 and ... Read more >>

Am. J. Epidemiol. (American journal of epidemiology)
[2017, 186(6):696-708]

Cited: 5 times

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Timed response to inhaled nitric oxide in pulmonary hypertension.

James M Hunt, Michael G Risbano, John C Messenger, John Carroll, David Badesch, Brian D Lowes, Ivan P Casserly, Joseph Kay, Todd M Bull,

Pulm Circ (Pulmonary circulation)
[2014, 4(1):103-109]

Cited: 1 time

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Exploring Clinical and Epidemiological Characteristics of Interstitial Lung Diseases: Rationale, Aims, and Design of a Nationwide Prospective Registry--The EXCITING-ILD Registry.

Michael Kreuter, Felix J F Herth, Margarethe Wacker, Reiner Leidl, Andreas Hellmann, Michael Pfeifer, Jürgen Behr, Sabine Witt, Dagmar Kauschka, Marcus Mall, Andreas Günther, Philipp Markart,

Despite a number of prospective registries conducted in past years, the current epidemiology of interstitial lung diseases (ILD) is still not well defined, particularly regarding the prevalence and incidence, their management, healthcare utilisation needs, and healthcare-associated costs. To address these issues in Germany, a new prospective ILD registry, "Exploring Clinical ... Read more >>

Biomed Res Int (BioMed research international)
[2015, 2015:123876]

Cited: 4 times

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Prospective study of BMI and the risk of pulmonary embolism in women.

Christopher Kabrhel, Raphaëlle Varraso, Samuel Z Goldhaber, Eric B Rimm, Carlos A Camargo,

Pulmonary embolism (PE) is common and associated with significant morbidity and mortality. An association between obesity and PE has been suggested, but the nature of the association has not been well defined. We performed a prospective cohort study of 87,226 women in the Nurses' Health Study (1984-2002) to define the ... Read more >>

Obesity (Silver Spring) (Obesity (Silver Spring, Md.))
[2009, 17(11):2040-2046]

Cited: 42 times

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Response to inhaled nitric oxide predicts survival in patients with pulmonary hypertension.

Richard A Krasuski, Ganesh P Devendra, Stephen A Hart, Andrew Wang, J Kevin Harrison, Thomas M Bashore,

OBJECTIVE: To examine the ability of vasodilator response to predict survival in a diverse cohort of patients with pulmonary hypertension (PH). PATIENTS & METHODS: A total of 214 consecutive treatment-naive patients referred for invasive PH evaluation were enrolled between November 1998 and December 2008. Vasoreactivity was assessed during inhalation of ... Read more >>

J. Card. Fail. (Journal of cardiac failure)
[2011, 17(4):265-271]

Cited: 4 times

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Transition from prostacyclin analogue infusion to oral therapy in patients with pulmonary arterial hypertension: a 5-year follow-up.

Esteban Escolar, Andrés M Pineda, Barbara Correal, Tahir Ahmed,

Transition from prostacyclin analogue infusion to oral therapy in patients with pulmonary arterial hypertension (PAH) is possible with acceptable short- and midterm results. However, there is a paucity of data on long-term outcomes after successful transition. Using a predefined protocol, transition to oral therapy was attempted in 22 patients with ... Read more >>

Pulm Circ (Pulmonary circulation)
[2013, 3(4):880-888]

Cited: 3 times

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Increased Umbilical Cord PAI-1 Levels in Placental Insufficiency Are Associated with Fetal Hypoxia and Angiogenesis.

Maxim D Seferovic, Madhulika B Gupta,

In intrauterine growth restriction (IUGR), a subset of pregnancies undergoes placental vascular dysregulation resulting in restricted blood flow and fetal hypoxemia. Altered transcription of hypoxic regulated plasminogen activator inhibitor 1 (PAI-1) has been associated with pregnancy complications and angiogenic regulation. Here we assessed circulating PAI-1 as an indicator of placental ... Read more >>

Dis. Markers (Disease markers)
[2016, 2016:7124186]

Cited: 12 times

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Sex and haemodynamics in pulmonary arterial hypertension.

Corey E Ventetuolo, Amy Praestgaard, Harold I Palevsky, James R Klinger, Scott D Halpern, Steven M Kawut,

Female sex is a risk factor for pulmonary arterial hypertension (PAH), yet females have better survival than males. We sought to determine if sex was associated with baseline haemodynamics in subjects with PAH, and whether age modified these relationships. We conducted a pooled analysis from 11 randomised trials submitted to ... Read more >>

Eur. Respir. J. (The European respiratory journal)
[2014, 43(2):523-530]

Cited: 24 times

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Preoperative plasma club (clara) cell secretory protein levels are associated with primary graft dysfunction after lung transplantation.

R J Shah, N Wickersham, D J Lederer, S M Palmer, E Cantu, J M Diamond, S M Kawut, V N Lama, S Bhorade, M Crespo, E Demissie, J Sonett, K Wille, J Orens, A Weinacker, P Shah, S Arcasoy, D S Wilkes, J D Christie, L B Ware, ,

Inherent recipient factors, including pretransplant diagnosis, obesity and elevated pulmonary pressures, are established primary graft dysfunction (PGD) risks. We evaluated the relationship between preoperative lung injury biomarkers and PGD to gain further mechanistic insight in recipients. We performed a prospective cohort study of recipients in the Lung Transplant Outcomes Group ... Read more >>

Am. J. Transplant. (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
[2014, 14(2):446-452]

Cited: 5 times

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Frequency of edema in patients with pulmonary arterial hypertension receiving ambrisentan.

Shelley Shapiro, David M Pollock, Hunter Gillies, Noreen Henig, Martine Allard, Christiana Blair, Crystal Anglen, Donald E Kohan,

Edema is a common side effect of endothelin receptor antagonists. Ambrisentan is an endothelin type A-selective endothelin receptor antagonist approved for the treatment of pulmonary arterial hypertension. We examined the clinical outcomes of patients who developed edema with and without ambrisentan treatment in 2 phase III, randomized placebo-controlled trials, ambrisentan ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2012, 110(9):1373-1377]

Cited: 19 times

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International Classification of Diseases coding changes lead to profound declines in reported idiopathic pulmonary arterial hypertension mortality and hospitalizations: implications for database studies.

Jeffrey Link, Craig Glazer, Fernando Torres, Kelly Chin,

Database studies have reported several associations between the diagnosis of idiopathic pulmonary arterial hypertension (IPAH) and mortality attributable to IPAH, including older age, black race, and diabetes.We investigated reported deaths and hospital discharges coded as IPAH and compared these with other forms of pulmonary hypertension. Three databases were used: the ... Read more >>

Chest (Chest)
[2011, 139(3):497-504]

Cited: 18 times

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Heart rate responses during the 6-minute walk test in pulmonary arterial hypertension.

S Provencher, D Chemla, P Hervé, O Sitbon, M Humbert, G Simonneau,

Patients with pulmonary arterial hypertension (PAH) exhibit a limited increase in stroke volume on exercise, and the heart rate (HR) increases may reflect the main mechanism that allows cardiac output to increase. The current prospective study documented the contribution of HR to the 6-min walking distance (6MWD) in idiopathic (IPAH) ... Read more >>

Eur. Respir. J. (The European respiratory journal)
[2006, 27(1):114-120]

Cited: 46 times

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Prospective study of diet and venous thromboembolism in US women and men.

Raphaëlle Varraso, Christopher Kabrhel, Samuel Z Goldhaber, Eric B Rimm, Carlos A Camargo,

The authors investigated diet as a risk factor for the development of venous thromboembolism (VTE) among 129,430 US women and men in the Nurses' Health Study and Health Professionals Follow-up Study. There were 2,892 cases of VTE from 1984 through 2008. Information on participants' dietary intakes was collected every 2-4 ... Read more >>

Am. J. Epidemiol. (American journal of epidemiology)
[2012, 175(2):114-126]

Cited: 27 times

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Severe pulmonary hypertension in idiopathic nonspecific interstitial pneumonia.

Robert W Hallowell, Robert M Reed, Mostafa Fraig, Maureen R Horton, Reda E Girgis,

Pulmonary hypertension (PH) is a common complication of interstitial lung disease (ILD), particularly in idiopathic pulmonary fibrosis (IPF) and ILD associated with connective tissue disease, where the underlying pathology is often a nonspecific interstitial pneumonia (NSIP) pattern. The degree of PH in ILD is typically mild to moderate and radiographic ... Read more >>

Pulm Circ (Pulmonary circulation)
[2012, 2(1):101-106]

Cited: 6 times

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Prospective, observational study of voriconazole therapeutic drug monitoring among lung transplant recipients receiving prophylaxis: factors impacting levels of and associations between serum troughs, efficacy, and toxicity.

Dimitra Mitsani, M Hong Nguyen, Ryan K Shields, Yoshiya Toyoda, Eun J Kwak, Fernanda P Silveira, Joseph M Pilewski, Maria M Crespo, Christian Bermudez, Jay K Bhama, Cornelius J Clancy,

Voriconazole prophylaxis is common following lung transplantation, but the value of therapeutic drug monitoring is unknown. A prospective, observational study of lung transplant recipients (n = 93) receiving voriconazole prophylaxis was performed. Serum voriconazole troughs (n = 331) were measured by high-pressure liquid chromatography. The median initial and subsequent troughs ... Read more >>

Antimicrob. Agents Chemother. (Antimicrobial agents and chemotherapy)
[2012, 56(5):2371-2377]

Cited: 51 times

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A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.

Pierre-Emmanuel Morange, Irene Bezemer, Noémie Saut, Lance Bare, Gwenaelle Burgos, Jessy Brocheton, Hervé Durand, Christine Biron-Andreani, Jean-Francois Schved, Gilles Pernod, Pilar Galan, Ludovic Drouet, Diana Zelenika, Marine Germain, Viviane Nicaud, Simon Heath, Ewa Ninio, Aurélien Delluc, Thomas Münzel, Tanja Zeller, Stefan-Martin Brand-Herrmann, Marie-Christine Alessi, Laurence Tiret, Mark Lathrop, François Cambien, Stefan Blankenberg, Joseph Emmerich, David-Alexandre Trégouët, Frits R Rosendaal,

To identify genetic susceptibility factors conferring increased risk of venous thrombosis (VT), we conducted a multistage study, following results of a previously published GWAS that failed to detect loci for developing VT. Using a collection of 5862 cases with VT and 7112 healthy controls, we identified the HIVEP1 locus on ... Read more >>

Am. J. Hum. Genet. (American journal of human genetics)
[2010, 86(4):592-595]

Cited: 38 times

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