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Neuromuscular Scoliosis

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Seromas Following Pediatric Spinal Deformity Surgery: Is Operative Management Necessary?

James Yu, Anne M Dumaine, Connie Poe-Kochert, George H Thompson, R Justin Mistovich,

BACKGROUND:Seromas are known complications after pediatric spinal deformity surgery. Although many surgeons perform an early debridement to prevent deep surgical site infections (SSIs), a less invasive approach to seroma management has not been studied. We hypothesized that a conservative approach to seroma management would be safe and yield equivalent outcomes. ... Read more >>

J Pediatr Orthop (Journal of pediatric orthopedics)
[2020, 40(4):e277-e282]

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Cerebral palsy with dislocated hip and scoliosis: what to deal with first?

Ilkka J Helenius, Elke Viehweger, Rene M Castelein,

Purpose:Hip dislocation and scoliosis are common in children with cerebral palsy (CP). Hip dislocation develops in 15% and 20% of children with CP, mainly between three and six years of age and especially in the spastic and dyskinetic subtypes. The risk of scoliosis increases with age and increasing disability as ... Read more >>

J Child Orthop (Journal of children's orthopaedics)
[2020, 14(1):24-29]

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Correlation between surgical site infection and classification of early onset scoliosis (C-EOS) in patients managed by rib-based distraction instrumentation.

Patrick J Cahill, Mahmoud A Mahmoud, Elle M MacAlpine, Aaron M Tatad, Robert M Campbell, John M Flynn,

OBJECTIVES:The aim of this study is to determine risk factors for infection among EOS patients treated by rib-based distraction instrumentation, and to further assess the incidence of infection among C-EOS categories and sub-types. Despite the heterogonous nature of early onset scoliosis, the classification of early onset scoliosis (C-EOS) has proven ... Read more >>

Spine Deform (Spine deformity)
[2020, :]

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Anterior Lengthening in Scoliosis Occurs Only in the Disc and is Similar in Different Types of Scoliosis.

Steven de Reuver, Rob C Brink, Jelle F Homans, Ludvig Vavruch, Hans Tropp, Moyo C Kruyt, Marijn van Stralen, René M Castelein,

BACKGROUND CONTEXT:Relative anterior spinal overgrowth (RASO) was proposed as a generalized growth disturbance and a potential initiator of adolescent idiopathic scoliosis (AIS). However, anterior lengthening has also been observed in neuromuscular (NM) scoliosis and was shown to be restricted to the apical areas and located in the intervertebral discs, not ... Read more >>

Spine J (The spine journal : official journal of the North American Spine Society)
[2020, :]

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Should instrumented spinal fusion in nonambulatory children with neuromuscular scoliosis be extended to L5 or the pelvis?

Niklas Tøndevold, Markus Lastikka, Thomas Andersen, Martin Gehrchen, Ilkka Helenius,

AIMS:It is uncertain whether instrumented spinal fixation in nonambulatory children with neuromuscular scoliosis should finish at L5 or be extended to the pelvis. Pelvic fixation has been shown to be associated with up to 30% complication rates, but is regarded by some as the standard for correction of deformity in ... Read more >>

Bone Joint J (The bone & joint journal)
[2020, 102-B(2):261-267]

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Spinal cord injury in infancy: activity-based therapy impact on health, function, and quality of life in chronic injury.

Laura C Argetsinger, Goutam Singh, Scott G Bickel, Margaret L Calvery, Andrea L Behrman,

INTRODUCTION:Spinal cord injury (SCI) in infancy magnifies the complexity of a devastating diagnosis. Children injured so young have high incidences of scoliosis, hip dysplasia, and respiratory complications leading to poor health and outcomes. We report the medical history, progression of rehabilitation, usual care and activity-based therapy, and outcomes for a ... Read more >>

Spinal Cord Ser Cases (Spinal cord series and cases)
[2020, 6(1):13]

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Impact of scoliosis surgery on pulmonary function in patients with muscular dystrophies and spinal muscular atrophy.

Harold J Farber, William A Phillips, Kenneth L Kocab, Darrell S Hanson, John A Heydemann, Benny T Dahl, Elizabeth T Spoede, Larry S Jefferson,

BACKGROUND:Scoliosis is a common complication of severe neuromuscular diseases. The aim of this study is to determine the impact of posterior spinal fusion on pulmonary function parameters in patients with severe neuromuscular disease at our medical center. METHODS:Retrospective chart review of all patients with severe neuromuscular disease who had posterior ... Read more >>

Pediatr. Pulmonol. (Pediatric pulmonology)
[2020, 55(4):1037-1042]

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PIEZO2: A Novel Molecule Involved in the Development of AIS.

Zhichong Wu, Yuwen Wang, Chao Xia, Zhenhua Feng, Yong Qiu, Jack Chun-Yiu Cheng, Leilei Xu, Zezhang Zhu,

STUDY DESIGN:A case-control study. OBJECTIVE:This study aimed to investigate the potential role of PIEZO2 gene in the development of AIS. SUMMARY OF BACKGROUND DATA:Mutations of PIEZO2 gene have been reported to be associated with progressive scoliosis and impaired proprioception. Previous studies showed that patients with AIS may have impaired proprioception. ... Read more >>

Spine (Spine)
[2020, 45(3):E120-E125]

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Proximal junction kyphosis after posterior spinal fusion for early-onset scoliosis.

Lucas Piantoni, Rodrigo G Remondino, Carlos A Tello, Ida A Francheri Wilson, Eduardo Galaretto, Mariano A Noel,

STUDY DESIGN:Retrospective study. OBJECTIVE:The aim of this study was to assess the presence of proximal junctional kyphosis (PJK) in our population of children with early-onset scoliosis (EOS) and to identify the predisposing factors for the development of PJK in the postoperative period after posterior spinal fusion (PSF). Few studies have ... Read more >>

Spine Deform (Spine deformity)
[2020, 8(2):311-316]

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Using lean principles to introduce intraoperative navigation for scoliosis surgery.

Derek T Cawley, Vijay Rajamani, Michael Cawley, Susanne Selvadurai, Alexander Gibson, Sean Molloy,

AIMS:Intraoperative 3D navigation (ION) allows high accuracy to be achieved in spinal surgery, but poor workflow has prevented its widespread uptake. The technical demands on ION when used in patients with adolescent idiopathic scoliosis (AIS) are higher than for other more established indications. Lean principles have been applied to industry ... Read more >>

Bone Joint J (The bone & joint journal)
[2020, 102-B(1):5-10]

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Health and Economic Outcomes of Posterior Spinal Fusion for Children With Neuromuscular Scoliosis.

Jody L Lin, Daniel S Tawfik, Ribhav Gupta, Meghan Imrie, Eran Bendavid, Douglas K Owens,

OBJECTIVES:Neuromuscular scoliosis (NMS) can result in severe disability. Nonoperative management minimally slows scoliosis progression, but operative management with posterior spinal fusion (PSF) carries high risks of morbidity and mortality. In this study, we compare health and economic outcomes of PSF to nonoperative management for children with NMS to identify opportunities ... Read more >>

Hosp Pediatr (Hospital pediatrics)
[2020, 10(3):257-265]

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Incidence of complications in the management of non-ambulatory neuromuscular early-onset scoliosis with a rib-based growing system: high- versus low-tone patients.

Norman Ramirez, Gerardo Olivella, Omar Rodriguez, Pablo Marrero, John Smith, Sumeet Garg, Michael Vitale, Tricia St Hilaire, Randal Betz,

PURPOSE:The purpose of this study is to evaluate whether patients with high-tone neuromuscular early-onset scoliosis have different surgical outcome and complication rate, when compared to patients with low-tone neuromuscular early-onset scoliosis treated with a rib-to-pelvis rib-based dual growing system. METHODS:This is a retrospective cohort study of 67 neuromuscular early-onset scoliosis ... Read more >>

Eur J Orthop Surg Traumatol (European journal of orthopaedic surgery & traumatology : orthopedie traumatologie)
[2019, :]

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Rare Cases of PLOD1-Related Kyphoscoliotic Ehlers-Danlos Syndrome in a Korean Family Identified by Next Generation Sequencing.

Young Lim Shin, You Na Park, Mi Ae Jang,

Kyphoscoliotic Ehlers-Danlos syndrome (kEDS) is an autosomal recessive connective tissue disorder characterized by muscular hypotonia, hyperextensible skin, skin fragility, joint hypermobility, and progressive kyphoscoliosis. The disorder results from a deficiency of the enzyme collagen lysyl hydroxylase 1 due to mutations in the gene PLOD1. We describe the rare cases of ... Read more >>

J. Korean Med. Sci. (Journal of Korean medical science)
[2020, 35(10):e96]

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The Correlation of Spinopelvic Parameters With Biomechanical Parameters Measured by Gait and Balance Analyses in Patients With Adult Degenerative Scoliosis.

Ram Haddas, Xiaobang Hu, Isador H Lieberman,

STUDY DESIGN:A prospective cohort study. OBJECTIVE:The objective of this study was to establish the correlation between radiographic spinopelvic parameters with objective biomechanical measures of function in patients with adult degenerative scoliosis (ADS). SUMMARY OF BACKGROUND DATA:Gait and balance analyses can provide an objective measure of function. Patients with ADS demonstrate ... Read more >>

Clin Spine Surg (Clinical spine surgery)
[2020, 33(1):E33-E39]

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Variability in length of stay following neuromuscular spinal fusion.

Nicholas D Fletcher, Laura L Bellaire, Eric S Dilbone, Laura A Ward, Robert W Bruce,

BACKGROUND:Patients with neuromuscular scoliosis (NMS) who undergo posterior spinal fusion (PSF) often have long, protracted hospital stays because of numerous comorbidities. Coordinated perioperative pathways can reduce length of hospitalization (LOH) without increasing complications; however, a subset of patients may not be suited to rapid mobilization and early discharge. METHODS:197 patients ... Read more >>

Spine Deform (Spine deformity)
[2020, :]

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Bigger is better: larger thoracic height is associated with increased health related quality of life at skeletal maturity.

Benjamin D Roye, Matthew E Simhon, Hiroko Matsumoto, Sumeet Garg, Gregory Redding, Amer Samdani, John T Smith, Paul Sponseller, Michael G Vitale, , ,

STUDY DESIGN:Cross sectional OBJECTIVES: The purpose of this study is to evaluate the association between thoracic height and health-related quality of life (HRQoL) at skeletal maturity in patients with EOS. Current literature suggests a minimum thoracic height of 18 cm to 22 cm to avoid poor pulmonary function and related health outcomes. ... Read more >>

Spine Deform (Spine deformity)
[2020, :]

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Unplanned return to OR (UPROR) for children with early onset scoliosis (EOS): a comprehensive evaluation of all diagnoses and instrumentation strategies.

Jason B Anari, John M Flynn, Patrick J Cahill, Michael G Vitale, John T Smith, Jaime A Gomez, Sumeet Garg, Keith D Baldwin, ,

STUDY DESIGN:Retrospective analysis of a prospectively collected multicenter database. OBJECTIVES:Our goal was to study unplanned return to the OR (UPROR, a postoperative complication that could not be treated without an additional anesthetic) as a function of C-EOS diagnosis and implant type. Growing concerns over the impact of multiple anesthetic events ... Read more >>

Spine Deform (Spine deformity)
[2020, 8(2):295-302]

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Reproducibility of the classification of early onset scoliosis (C-EOS).

Casper Dragsted, Søren Ohrt-Nissen, Dennis Winge Hallager, Niklas Tøndevold, Thomas Andersen, Benny Dahl, Martin Gehrchen,

STUDY DESIGN:Reproducibility study. OBJECTIVES:Assess the agreement and reliability of the classification of early onset scoliosis (C-EOS). C-EOS is a promising tool for patients with early onset scoliosis (EOS). However, the reliability has only been examined without measuring radiographs and not including the annual progression rate (APR) modifier. METHODS:We included a ... Read more >>

Spine Deform (Spine deformity)
[2020, 8(2):285-293]

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Deep Infections After Pediatric Spinal Arthrodesis: Differences Exist with Idiopathic, Neuromuscular, or Genetic and Syndromic Cause of Deformity.

Brian T Sullivan, Oussama Abousamra, Varun Puvanesarajah, Amit Jain, Matthew J Hadad, Aaron M Milstone, Paul D Sponseller,

BACKGROUND:Little is known about the rates, timing, and causative microorganisms of deep surgical site infections after spinal arthrodesis in patients with genetic and syndromic scoliosis compared with patients with adolescent idiopathic scoliosis and kyphosis or patients with neuromuscular scoliosis. METHODS:We reviewed data from 1,353 patients who were <21 years of ... Read more >>

J Bone Joint Surg Am (The Journal of bone and joint surgery. American volume)
[2019, 101(24):2219-2225]

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Magnetic Controlled Growth Rods in the Treatment of Scoliosis: Safety, Efficacy and Patient Selection.

Athanasios I Tsirikos, Simon B Roberts,

AbstractEarly-onset scoliosis is defined as a spinal curvature greater than 10° in children prior to 10 years of age. Untreated EOS may lead to progressively severe spinal deformity, impaired pulmonary development, restrictive lung disease, and both increased morbidity and mortality. Limitations of established conservative treatments include inability to correct severe ... Read more >>

Med Devices (Auckl) (Medical Devices (Auckland, N.Z.))
[2020, 13:75-85]

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Sublaminar polyester bands for the correction of idiopathic and neuromuscular scoliosis.

Federico Canavese, Antoine Samba,

Recent literature suggests that sublaminar bands (SB) can provide good coronal plane correction, comparable to pedicle screw constructs, as well as good correction in the sagittal plane, even in patients with preoperative hypokyphosis; comparable results have been reported in patients with adolescent idiopathic scoliosis (AIS) and in patients with neuromuscular ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2020, 8(2):32]

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Intraoperative neuromonitoring in spine deformity surgery: modalities, advantages, limitations, medicolegal issues - surgeons' views.

Mirza Biscevic, Aida Sehic, Ferid Krupic,

In spine deformity surgery, iatrogenic neurologic injuries might occur due to the mechanical force applied to the spinal cord from implants, instruments, and bony structures, or due to ischemic changes from vessel ligation during exposure and cord distraction/compression during corrective manoeuvres.Prompt reaction within the reversible phase (reducing of compressive/distractive forces) ... Read more >>

EFORT Open Rev (EFORT open reviews)
[2020, 5(1):9-16]

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Pedicle screw instrumentation with or without pelvic fixation in neuromuscular scoliosis: Outcome and complications in a series of 37 patients with a minimum 2-year follow-up.

Norbert Stiel, Jasmin Özden, Karsten Ridderbusch, Menard Moritz, Philip Kunkel, Amit Gulati, Christian Hagemann, Kiril Mladenov, Ralf Stuecker, Alexander S Spiro,

OBJECTIVE:Neuromuscular scoliosis (NMS) is often associated with rapid progressive spinal deformities. Indications, when to extend the instrumentation to the pelvis for pelvic obliquity are not generally accepted at this time. This study reports on the indications, surgical technique and results using pedicle screw instrumentation exclusively with or without pelvic fixation ... Read more >>

Surgeon (The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland)
[2020, :]

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Spine deformities in patients with cerebral palsy; the role of the pelvis.

Carol Hasler, Reinald Brunner, Alon Grundshtein, Dror Ovadia,

Introduction:Progressive neuromuscular spinal deformities with pelvic obliquity and loss of sitting balance are typical features of severely affected patients with cerebral palsy. The pelvis represents the key bone between the spine and the lower extremity when it comes to deciding whether and when to operate and if spine or hip ... Read more >>

J Child Orthop (Journal of children's orthopaedics)
[2020, 14(1):9-16]

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Technical aspects of surgical correction of spinal deformities in cerebral palsy.

Jorge Mineiro, Muharrem Yazici,

Purpose:Cerebral palsy (CP) is a disorder arising from a non-progressive lesion in the developing immature brain with an encephalopathy, that results in various levels of motor and sensory dysfunction. Motor disability of these children can be assessed by the Gross Motor Function Classification System in five levels, and depending on ... Read more >>

J Child Orthop (Journal of children's orthopaedics)
[2020, 14(1):30-40]

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