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A null allele in the wdfy-3 selective autophagy gene of C. elegans .

Tyler Buddell, Christopher Quinn,

The <i>C. elegans</i> WDFY-3 protein is important for cargo selection during selective autophagy and for regulating axon termination. The C-terminal region of WDFY-3 contains BEACH, WD repeats, and FYVE-like domains, all of which are required for selective autophagy. WDFY-3 also contains a large N-terminal region that is relatively uncharacterized. Currently, ... Read more >>

MicroPubl Biol (microPublication biology)
[2022, 2022:]

Cited: 0 times

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The disconnect2 mutation disrupts the tjp1b gene that is required for electrical synapse formation.

Jennifer Carlisle Michel, Abagael M Lasseigne, Audrey J Marsh, Adam C Miller,

To investigate electrical synapse formation <i>in vivo</i> we used forward genetics to disrupt genes affecting Mauthner cell electrical synapses in larval zebrafish. We identify the <i>disconnect2</i> ( <i>dis2</i> ) mutation for its failure to localize neural gap junction channels at electrical synapses. We mapped this mutation to chromosome 25 and ... Read more >>

MicroPubl Biol (microPublication biology)
[2022, 2022:]

Cited: 0 times

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