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Neuro ophthalmic Manifestations of Vascular Eye Diseases

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Diagnostic challenges in a case of an isolated third nerve palsy.

Priya Sivakumar, Savithri Palanive, Debasis Gochait, Olivia Hess,

Purpose:Neuro-ophthalmic manifestations may be the first and sole presenting feature of a nasopharyngeal carcinoma. Peri-neural spread is an emerging phenomenon that explains the distant spread of tumour cells well beyond the local extent of invasion. This under recognized route of tumour spread often results in delayed diagnosis and reduced life ... Read more >>

Am J Ophthalmol Case Rep (American journal of ophthalmology case reports)
[2020, 18:100585]

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Bilateral corneal perforation and iris prolapse as a complication non-peripheral ulcerative keratitis in a patient with fulminant granulomatosis with polyangiitis: a case report.

Andrés Vargas-Villanueva, Natalia Carvajal-Saiz, Juliana Muñoz-Ortiz, Alejandra de-la-Torre,

J Ophthalmic Inflamm Infect (Journal of ophthalmic inflammation and infection)
[2020, 10(1):2]

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Orbital Apex Syndrome: A Review.

Akshay Badakere, Preeti Patil-Chhablani,

Orbital apex syndrome is characterized by vision loss from optic neuropathy and ophthalmoplegia due to the involvement of ocular motor nerves in the anatomical region of the orbital apex. Patients could present with signs and symptoms deriving from the involvement of structures within the orbital apex, the superior orbital fissure ... Read more >>

Eye Brain (Eye and brain)
[2019, 11:63-72]

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Spaceflight associated neuro-ocular syndrome (SANS) and the neuro-ophthalmologic effects of microgravity: a review and an update.

Andrew G Lee, Thomas H Mader, C Robert Gibson, William Tarver, Pejman Rabiei, Roy F Riascos, Laura A Galdamez, Tyson Brunstetter,

Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity associated findings collectively define the "Spaceflight Associated Neuro-ocular Syndrome" (SANS). We compare and contrast prior published work on SANS by the National Aeronautics and Space Administration's (NASA) Space Medicine Operations Division with ... Read more >>

NPJ Microgravity (NPJ Microgravity)
[2020, 6:7]

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Underlying Ehlers-Danlos syndrome discovered during neuro-ophthalmic evaluation of concussion patients: a case series.

Abhishek Gami, Eric L Singman,

BACKGROUND:The Ehlers-Danlos syndromes are a heterogenous group of diseases that cause connective tissue defects. At present, there are no published reports focusing upon the neuro-ophthalmic symptoms that might occur in EDS patients after mild traumatic brain injury. The demographics and clinical course of seven patients with subclinical EDS and mild ... Read more >>

BMC Ophthalmol (BMC ophthalmology)
[2019, 19(1):159]

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Bilateral nongranulomatous uveitis with transposition of the great arteries: A rare case report.

Dipankar Das, Saurabh Deshmukh, Harsha Bhattacharjee, Krati Gupta, Pranjal Mishra,

In this case report, we describe for the first time an association between transposition of the great arteries (TGAs), a congenital heart disease, and uveitis. We hope that this atypical finding in a patient with TGA will add to the clinical spectrum of ophthalmic conditions that can be seen with ... Read more >>

Oman J Ophthalmol (Oman journal of ophthalmology)
[2019, 12(3):191-193]

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An Unusual Combination of Neurological Manifestations and Sudden Vision Loss in a Child with Familial Hyperphosphatemic Tumoral Calcinosis.

Lokesh Lingappa, Shoji Ichikawa, Amie K Gray, Dena Acton, Michael J Evans, Rajsekara Chakravarthi Madarasu, Ramesh Kekunnaya, Sirisharani Siddaiahagari,

Hyperphosphatemia in the absence of renal failure is an unusual occurrence, particularly in children, but is a common primary feature of familial hyperphosphatemic tumor calcinosis. We report a child with hyperphosphatemia who presented with multiple episodes of neurologic dysfunction involving lower motor neuron facial nerve palsy along with sequential visual ... Read more >>

Ann Indian Acad Neurol (Annals of Indian Academy of Neurology)
[2019, 22(3):327-331]

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Neuro-Ophthalmic Literature Review.

David Bellows, Noel Chan, John Chen, Hui-Chen Cheng, Rauan Kaiyrzhanov, Peter MacIntosh, Michael Vaphiades,

Neuroophthalmology (Neuro-Ophthalmology)
[2019, 43(2):126-130]

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Commentary: Tuberculosis in neuro ophthalmology - How different it is?

Sivaraman Bala Murugan, Priya Sundaralakshmi,

Indian J Ophthalmol (Indian journal of ophthalmology)
[2019, 67(7):1212-1214]

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Neuro-ophthalmological manifestations of tuberous sclerosis: current perspectives.

Michael J Wan, Ka Lo Chan, Benjamin G Jastrzembski, Asim Ali,

Tuberous sclerosis complex (TSC) is a complex, multi-system disorder with a well-described underlying genetic etiology. While retinal findings are common in TSC and important in establishing the diagnosis, TSC also has many potential neuro-ophthalmology manifestations. The neuro-ophthalmology manifestations of TSC can have a significant impact on visual function and are ... Read more >>

Eye Brain (Eye and brain)
[2019, 11:13-23]

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Bilateral Optic Disc Edema in a Patient with Lead Poisoning.

Kaveh Abri Aghdam, Amin Zand, Mostafa Soltan Sanjari,

Purpose:Heavy metals, such as lead can cause optic neuropathy. Optic disc neuropathy due to lead intoxication has previously been reported. We report a rare case of lead toxicity-induced optic neuropathy presenting with bilateral hemorrhagic optic disc swelling. Case Report:The patient was a 42-year-old man with a history of chronic oral ... Read more >>

J Ophthalmic Vis Res (Journal of ophthalmic & vision research)
[2019, 14(4):513-517]

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Light-induced Amaurosis: A Rare Manifestation of Internal Carotid Artery Stenosis.

Ru Jin Eugene Ting, Michelle Hui, Catherine Thoo, Minas T Coroneo, Ian C Francis,

Light-induced amaurosis (LIA) is a rare presentation of internal carotid artery (ICA) stenosis. This report documents a 74-year-old Caucasian male who presented with profound right monocular vision loss, occurring on every occasion upon entering brightly lit environments. This was managed successfully with a right carotid endarterectomy. This case is presented to ... Read more >>

Cureus (Cureus)
[2019, 11(10):e5817]

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Seesaw nystagmus with internuclear ophthalmoplegia from bilateral dorsomedial pons and left thalamus infarction: a case report.

Qian Zhang, Jian Li,

BACKGROUND:We describe for the first time the clinical features and mechanisms of a bilateral dorsomedial pons and left thalamus infarction with seesaw nystagmus and internuclear ophthalmoplegia. CASE PRESENTATION:A 62-year-old Chinese man was hospitalized for sudden-onset dizziness, diplopia, and gait disturbance. A neurological examination revealed seesaw nystagmus and internuclear ophthalmoplegia. Magnetic ... Read more >>

J Med Case Rep (Journal of medical case reports)
[2019, 13(1):352]

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Linear Scleroderma of the Head - Updates in management of Parry Romberg Syndrome and En coup de sabre: A rapid scoping review across subspecialties.

Daniel H. Glaser, Christina Schutt, Kaila Schollaert-Fitch, Kathryn Torok,

To provide an update on the current management, including evaluation and treatment, and the available diagnostic tools for linear scleroderma of the head, i.e., Parry-Romberg Syndrome and en coup de sabre (PRS/ECDS). A rapid scoping review of the literature was conducted to include manuscripts published in English between 2010 and ... Read more >>

(European Journal of Rheumatology)
[2020, 7(Suppl 1):S48-S57]

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Neuro-ophthalmic complications of IgG4-related disease.

Bart K Chwalisz, John H Stone,

PURPOSE OF REVIEW:IgG4-related disease (IgG4-RD) is increasingly recognized as a fibroinflammatory disease with a plethora of organ-specific manifestations but a particular predilection for head and neck tissues, including the nervous system. This review discusses general features and organ-specific presentations of IgG4-RD as well as treatment considerations, particularly emphasizing features of ... Read more >>

Curr Opin Ophthalmol (Current opinion in ophthalmology)
[2018, 29(6):485-494]

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Papilledema from gain-of-function mutations in the STAT3 gene.

Young-Woo Suh, Jonathan C Horton,

BACKGROUND:Signal Transducer and Activator of Transcription 3 (STAT3) gain-of-function germline mutations are associated with diverse clinical manifestations, including autoimmune cytopenia, lymphadenopathy, immunodeficiency, endocrinopathy, and enteropathy. We describe a new feature: raised intracranial pressure with papilledema. MATERIALS AND METHODS:Report of two cases. RESULTS:The first patient had a de novo heterozygous c.2144C>T ... Read more >>

Ophthalmic Genet. (Ophthalmic genetics)
[2019, 40(2):165-169]

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Case Series of Cancer-associated Retinopathy (CAR).

Srikanth Naramala, Jowairiyya Ahmad, Sreedhar Adapa, Frank Gavini, Venu Madhav Konala,

Cancer-associated retinopathy (CAR) is a rare paraneoplastic disorder of the retina leading to blindness, associated with multiple cancers. It can lead to rapid progressive visual deterioration with retinal pathology ranging from retinitis pigmentosa to retinal degeneration. It is caused by antibodies directed against retinal antigens. This uncommon syndrome is a ... Read more >>

Cureus (Cureus)
[2019, 11(6):e4872]

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Factors Affecting Repeatability of Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography in Healthy Subjects.

Taek Hoon Lee, Hyung Bin Lim, Ki Yup Nam, Kyeungmin Kim, Jung Yeul Kim,

Various factors can affect repeatability of optical coherence tomography angiography (OCTA) measurements, and they have not been studied sufficiently. We aimed to investigate the factors associated with the repeatability of automated superficial retinal vessel density (VD) and foveal avascular zone (FAZ) metrics acquired from OCTA. A total of 141 normal ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):16291]

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Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog.

Shin Ae Park, Dodd Sledge, Colleen Monahan, Joshua T Bartoe, András M Komáromy,

BACKGROUND:Open angle glaucoma is the only type of primary glaucoma reported in Beagles. This case report describes a primary angle-closure glaucoma in a Beagle and its diagnostic and prognostic relevance. CASE PRESENTATION:A 12-year-old, neutered male Beagle presented to the Michigan State University (MSU) Comparative Ophthalmology Service for evaluation of suspected ... Read more >>

BMC Vet. Res. (BMC veterinary research)
[2019, 15(1):75]

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Ocular Manifestations of Granulomatosis with Polyangiitis: A Review of the Literature.

Evdokia Sfiniadaki, Ioanna Tsiara, Panagiotis Theodossiadis, Irini Chatziralli,

Granulomatosis with polyangiitis (GPA) is a rare systemic autoimmune disease of unknown etiology that is characterized by granulomatous inflammation, tissue necrosis, and vasculitis in small- and medium-sized vessels. Ocular and orbital manifestations are common in almost half of patients with GPA, affecting every structure of the eye, from the eyelid ... Read more >>

Ophthalmol Ther (Ophthalmology and therapy)
[2019, 8(2):227-234]

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Homocysteinemia as a cause for amaurosis fugax in a patient without an apparent embolic source.

Sibel Inan, Guliz Yavas, Umit Ubeyt Inan,

Purpose: To report a case with monocular transient vision loss (TVL) associated with Hyperhomocysteinemia. Methods: We present a case with persistent TVL attacks and high level of homocysteine. Results: A 32-year-old male had a history of episodes of recurrent monocular TVL. Extensive ophthalmic, systemic and laboratory studies were unremarkable with ... Read more >>

Rom J Ophthalmol (Romanian journal of ophthalmology)
[2019, 63(2):188-192]

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Vasculitis with superior ophthalmic vein thrombosis compatible with neuro-neutrophilic disease.

Mari Sakamoto, Takuji Kurimoto, Sotaro Mori, Kaori Ueda, Yukako Keshi, Yuko Yamada, Atsushi Azumi, Taro Shimono, Makoto Nakamura,

Purpose:To present a unique case of neuro-neutrophilic disease with inflammation and thrombosis of the superior ophthalmic vein (SOV). Observations:A 43-year-old Japanese man with past histories of oculomotor paralysis, auditory disorder, ischemic enteritis, and recurrent oral ulceration was referred to our hospital because of blurred vision in his right eye. Ophthalmic ... Read more >>

Am J Ophthalmol Case Rep (American Journal of Ophthalmology Case Reports)
[2018, 12:39-44]

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Retinal vascular abnormalities in Sturge-Weber syndrome.

Dhanashree Ratra, Hitesh Yadav, Daleena Dalan, Preet Kanwar Singh Sodhi, Vineet Ratra,

Sturge-Weber syndrome (SWS) includes facial, leptomeningeal and choroidal hemangioma. The retinal vasculature is essentially normal. Rare cases of retinal vascular tortuosity and arterio-venous malformations have been reported. We report two cases with rare concomitant retinal vascular abnormalities along with SWS. Both the patients had nevus flammeus, hemifacial hypertrophy, and choroidal ... Read more >>

Indian J Ophthalmol (Indian journal of ophthalmology)
[2019, 67(7):1223-1226]

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Inpatient and Emergency Room Ophthalmology Consultations at a Tertiary Care Center.

Daniel J Oh, Levi N Kanu, Judy L Chen, Ahmad A Aref, William F Mieler, Peter W MacIntosh,

Background:An ophthalmology consultation service is of significant benefit to patients in the hospital and is an instructive component of a residency education program. Ophthalmology consultations in a hospital present unique challenges to those seen in an outpatient clinic, for which the consulting ophthalmologist should be prepared. The purpose of this ... Read more >>

J Ophthalmol (Journal of ophthalmology)
[2019, 2019:7807391]

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Sex Hormones and Optic Nerve Disorders: A Review.

Raffaele Nuzzi, Simona Scalabrin, Alice Becco, Giancarlo Panzica,

Aim: This review article presents a comprehensive overview of the literature on sex hormones (estrogens, androgens, progesterone) and optic nerve disorders, with a discussion of the implications for therapy and prevention. Methods: Epidemiological, pre-clinical and clinical studies were reviewed. Results: Analysis of the biological basis for a relationship between eye ... Read more >>

Front Neurosci (Frontiers in Neuroscience)
[2019, 13:57]

Cited: 1 time

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