Full Text Journal Articles about
Neural Tube Defects

Advertisement

Find full text journal articles






Spatiotemporal expression of leukemia inhibitory factor receptor protein during neural tube development in embryos with neural tube defects.

Dong An, Xiao-Wei Wei, He-Nan Zhang, Dan Liu, Wei Ma, Zheng-Wei Yuan,

Leukemia inhibitory factor receptor (LIFR), as a neuroregulatory cytokine receptor, generally shows a neuroprotective effect in central nervous system injuries. In this study, to understand the effect of LIFR on pathogenesis of neural tube defects, we explored spatiotemporal expression of LIFR at different stages of fetal development in normal and ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(4):705-711]

Cited: 0 times

View full text PDF listing >>



Mutations associated with human neural tube defects display disrupted planar cell polarity in Drosophila.

Ashley C Humphries, Sonali Narang, Marek Mlodzik,

Planar cell polarity (PCP) and neural tube defects (NTDs) are linked, with a subset of NTD patients found to harbour mutations in PCP genes, but there is limited data on whether these mutations disrupt PCP signaling in vivo. The core PCP gene Van Gogh (Vang), Vangl1/2 in mammals, is the ... Read more >>

Elife (eLife)
[2020, 9:]

Cited: 0 times

View full text PDF listing >>



Advertisement

Lower rates of neural tube defects in Israel following folic acid supplementation policy.

Annie Reiss, Matan J Cohen, Ehud Kaliner, Efrat Gabai Kapara, Amihood Singer, Itamar Grotto, Ronni Gamzu,

Neural tube defects (NTDs) are common and disabling congenital malformations that remain a public health challenge despite prevention efforts. In 2000, The Israeli Ministry of Health published recommendations on daily folic acid (FA) supplementation for women of reproductive age and established a national NTD registry. This study aims to evaluate ... Read more >>

Prev Med (Preventive medicine)
[2020, :106064]

Cited: 0 times

View full text PDF listing >>



Evolution of fetal acrania from 7 to 10 weeks gestation.

Lisa Hui, Simon Meagher,

Prenat. Diagn. (Prenatal diagnosis)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Dolutegravir and neural tube defects: a new insight.

Laurent Chouchana, Antoine Pariente, Emmanuelle Pannier, Vassilis Tsatsaris, Jean-Marc Treluyer,

Lancet Infect Dis (The Lancet. Infectious diseases)
[2020, 20(4):405-406]

Cited: 0 times

View full text PDF listing >>



Ultrasound Appearances of the Acrania-Anencephaly Sequence at 10 to 14 Weeks' Gestation.

Dagmar Wertaschnigg, Maya Reddy, Jayshree Ramkrishna, Fabricio da Silva Costa, Waldo Sepulveda, Daniel L Rolnik, Simon Meagher,

OBJECTIVES:The acrania-anencephaly sequence is a lethal condition with a high detection rate in experienced hands after 10 weeks' gestation. However, earlier in gestation, many cases remain undetected. Different phenotypic appearances have been described and might help increase the detection rate in less experienced hands and also earlier in gestation. The purpose ... Read more >>

J Ultrasound Med (Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Maternal use of folic acid and multivitamin supplements and infant risk of birth defects in Norway 1999-2013.

Trude Gildestad, Tone Bjørge, Øystein A Haaland, Kari Klungsøyr, Stein Emil Vollset, Nina Øyen,

The association between folic acid supplementation and birth defects other than neural tube defects remains unclear. We used a log-binomial regression model to investigate if periconceptional folic acid and/or multivitamin use was associated with birth defects in Norway with prospectively collected data from the Medical Birth Registry of Norway (MBRN) ... Read more >>

Br. J. Nutr. (The British journal of nutrition)
[2020, :1-38]

Cited: 0 times

View full text PDF listing >>



Fibronectin is a smart adhesive that both influences and responds to the mechanics of early spinal column development.

Emilie Guillon, Dipjyoti Das, Dörthe Jülich, Abdel-Rahman Hassan, Hannah Geller, Scott Holley,

An extracellular matrix of Fibronectin adheres the neural tube to the two flanking columns of paraxial mesoderm and is required for normal vertebrate development. Here, we find that the bilaterally symmetric interfaces between the zebrafish neural tube and paraxial mesoderm function as optimally engineered adhesive lap joints with rounded edges, ... Read more >>

Elife (eLife)
[2020, 9:]

Cited: 0 times

View full text PDF listing >>



Gestational exposure to valproic acid upregulates total Stat3 protein expression while downregulating phosphorylated Stat3 in CD-1 mouse embryos with neural tube defects.

Sidra Shafique, Louise M Winn,

Valproic acid (VPA), a widely prescribed antiepileptic drug and an effective treatment for psychiatric disorders, is teratogenic causing neural tube defects (NTDs) and other defects in the exposed embryo. Signal transducer and activator of transcription 3 (Stat3) is a transcription factor that is activated via tyrosine phosphorylation. Stat3, as well ... Read more >>

Birth Defects Res (Birth defects research)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Gene Expression Profile Associated With Neural Tube Defects Among Infants Attending Muhimbili National Hospital And Muhimbili Orthopaedic Institute In Tanzania

Mariam Sadallah, Evelyne Assenga, Charles Pallangyo, Karim Manji,

<title>Abstract</title> <p> Background Neural tube defects (NTDs) are severe congenital anomalies of the central nervous system. The specific cause is not known, though several factors including gene variants involving the folate metabolism have been implicated in the etiology. This study aimed at identifying the gene expression profile of ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Dolutegravir for pregnant women living with HIV.

Jonathan Zipursky, Mona Loutfy,

CMAJ (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne)
[2020, 192(9):E217-E218]

Cited: 0 times

View full text PDF listing >>



Gene Expression Profile Associated With Neural Tube Defects Among Infants Attending Muhimbili National Hospital And Muhimbili Orthopaedic Institute In Tanzania

Evelyne Assenga, Mariam Sadallah, Charles Pallangyo, Karim Manji,

<title>Abstract</title> <p> <bold>Background:</bold> Neural tube defects (NTDs) are severe congenital anomalies of the central nervous system. The specific cause is not known, though several factors including gene variants involving the folate metabolism have been implicated in the etiology. This study aimed at identifying the gene expression profile of ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Understanding Awareness and Consumption of Folic Acid among reproductive age women in Bahirdar Town, North west Ethiopia: a qualitative study.

Taye Zeru, betelihem Manaye,

<title>Abstract</title> <p> <bold>Background</bold>: Adequate maternal consumption of folic acid before pregnancy and during the early weeks of gestation can reduce the risk of having a child with a neural tube defect. Current guidance recommends that all women who could become pregnant should take a folic acid supplement before ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Is natural (6S)-5-methyltetrahydrofolic acid as effective as synthetic folic acid in increasing serum and red blood cell folate concentrations during pregnancy? A proof-of-concept pilot study

Crystal Karakochuk, Kelsey Cochrane, Chantal Mayer, Angela Devlin, Rajavel Elango, Jennifer Hutcheon,

<title>Abstract</title> <p> Background: North American health authorities recommend 0.4 mg/day folic acid before conception and throughout pregnancy to reduce the risk of neural tube defects. Folic acid is a synthetic form of folate that must be reduced by dihydrofolate reductase and then further metabolized. Recent evidence suggests that ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Neurosurgical training and global health education: systematic review of challenges and benefits of in-country programs in the care of neural tube defects.

Kellen Gandy, Heidi Castillo, Brandon G Rocque, Viachaslau Bradko, William Whitehead, Jonathan Castillo,

OBJECTIVE:The recognition that neurosurgeons harbor great potential to advocate for the care of individuals with neural tube defects (NTDs) globally has sounded as a clear call to action; however, neurosurgical care and training in low- and middle-income countries (LMICs) present unique challenges that must be considered. The objective of this ... Read more >>

Neurosurg Focus (Neurosurgical focus)
[2020, 48(3):E14]

Cited: 0 times

View full text PDF listing >>



Preconception folic acid supplementation use and the occurrence of neural tube defects in Japan.

Yuto Maeda, Eri Maeda, Naoko Arata,

Congenit Anom (Kyoto) (Congenital anomalies)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Association between maternal periconceptional alcohol consumption and neural tube defects: Findings from the National Birth Defects Prevention Study, 1997-2011.

Adia R Louden, Jonathan Suhl, Vijaya Kancherla, Kristin M Caspers Conway, Jennifer Makelarski, Meredith M Howley, Adrienne T Hoyt, Richard S Olney, Andrew F Olshan, Paul A Romitti, ,

BACKGROUND:Neural tube defects (NTD)s are common birth defects with a multifactorial etiology. Findings from human studies examining environmental (non-inherited) exposures tend to be inconclusive. In particular, although animal studies of alcohol exposure and NTDs support its teratogenic potential, human studies are equivocal. Using data from the National Birth Defects Prevention ... Read more >>

Birth Defects Res (Birth defects research)
[2020, 112(5):427-439]

Cited: 0 times

View full text PDF listing >>



Multiple Occipital Bone Lytic Lesions Containing Ectopic Cerebellar Parenchyma Mimicking Neoplasia.

Elizabeth Wild, Hai Sun, Maria-Magdalena Georgescu,

BACKGROUND:Nonlethal neural tube defects are developmental malformations with complex pathogenesis usually manifested at birth or in childhood. CASE DESCRIPTION:We report the case of a 61-year-old woman without significant previous clinical history presenting for neck pain and stiffness. An extensive workup detected multiple lytic lesions within the occipital bone and cervical ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 138:115-119]

Cited: 0 times

View full text PDF listing >>



One-carbon metabolism and folate transporter genes: Do they factor prominently in the genetic etiology of neural tube defects?

John W Steele, Sung-Eun Kim, Richard H Finnell,

Neural tube defects (NTDs) are a broad class of congenital birth defects that result from the failure of neural tube closure during neurulation. Folic acid supplementation has been shown to prevent the occurrence of NTDs by as much as 70% in some human populations, and folate deficiency in a pregnant ... Read more >>

Biochimie (Biochimie)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Association between body mass index and folate insufficiency indicative of neural tube defects risk among nonpregnant women of childbearing age in the United States, NHANES, 2007-2010.

Meryna Manandhar, Hind Beydoun, Vijaya Kancherla,

BACKGROUND:Maternal folate status and obesity are known risk factors for neural tube defects (NTD) in the offspring. We examined the association between body mass index (BMI) categories and blood folate concentrations, specifically, red blood cell (RBC) folate concentrations indicative of NTD risk among nonpregnant women of child-bearing age (20-44 years) in ... Read more >>

Birth Defects Res (Birth defects research)
[2020, 112(6):490-502]

Cited: 0 times

View full text PDF listing >>



Concentrations of rare earth elements in maternal serum during pregnancy and risk for fetal neural tube defects.

Jing Wei, Chengrong Wang, Shengju Yin, Xin Pi, Lei Jin, Zhiwen Li, Jufen Liu, Linlin Wang, Chenghong Yin, Aiguo Ren,

Rare earth elements (REEs) are ubiquitous in the environment. Animal experiments have shown that many REEs have adverse impacts on the health of fetuses. However, data from humans are scarce. In this study, we examined the associations between concentrations of 10 REEs in maternal serum and the risk for fetal ... Read more >>

Environ Int (Environment international)
[2020, 137:105542]

Cited: 0 times

View full text PDF listing >>



Craniorachischisis with Exencephaly.

Jessenia Guerrero, Debra S Heller, Ada Baisre de Leon,

Background: Neural tube defects can be as mild as spina bifida, to as severe as anencephaly, with only a fraction of these cases presenting as both craniorachischisis and exencephaly. Case report: The G3, P1011 mother was 25-years old, who at an estimated fetal gestational age of 17 weeks had a fetal ... Read more >>

Fetal Pediatr Pathol (Fetal and pediatric pathology)
[2020, :1-4]

Cited: 0 times

View full text PDF listing >>



Therapeutic Drug Monitoring of HIV Antiretroviral Drugs in Pregnancy: A Narrative Review.

Brendan OʼKelly, Ross Murtagh, John S Lambert,

To date, therapeutic drug monitoring (TDM) has played an important role in the management of pregnant HIV patients on highly active antiretroviral therapy. Historically, in pregnant women living with HIV, the third agent in triple therapy has been either non-nucleoside reverse transcriptase inhibitors or protease inhibitors (PIs). PIs have been ... Read more >>

Ther Drug Monit (Therapeutic drug monitoring)
[2020, 42(2):229-244]

Cited: 0 times

View full text PDF listing >>



Amniotic fluid concentrations of soluble endoglin and endothelial cell-specific molecule-1 in pregnancies complicated with neural tube defects.

Ali Ovayolu, Gamze Ovayolu, Tuncay Yuce, Murat Aykut Ozek, Ilkay Dogan, Nuray Bostancieri,

Objective To determine the concentrations of soluble endoglin (sCD105) and endothelial cell-specific molecule-1 (ESM-1) in the amniotic fluid (AF) of pregnant women, and to investigate the relationship between these concentrations and neural tube defects (NTDs). Methods AF concentrations of sCD105 and ESM-1 were measured in the study group, which included ... Read more >>

J Perinat Med (Journal of perinatal medicine)
[2020, 48(2):132-138]

Cited: 0 times

View full text PDF listing >>



Meningocele tourniquet syndrome.

Akhilesh Kumar, Nitin Pant, Anand Pandey, Ashish Wakhlu,

Tourniquet syndrome is a rare condition where a tourniquet applied to an appendage leads to an obstructed blood flow and subsequent ischemic injury. Meningomyelocele and meningocele are common birth defects, and involvement of meningocele in tourniquet syndrome is never mentioned in the literature. We managed a 10-day-old male child presenting ... Read more >>

Childs Nerv Syst (Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
2.2696 s