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Novel deletion alleles of a C. elegans gene Y48E1C.1, named as tm5468, tm5625 and tm5626.

Sayaka Hori, Yuji Suehiro, Sawako Yoshina, Shohei Mitani,

MicroPubl Biol (microPublication. Biology)
[2017, 2017:]

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Cesarean delivery and associated socioeconomic factors and neonatal survival outcome in Kenya and Tanzania: analysis of national survey data.

Malachi Ochieng Arunda, Anette Agardh, Benedict Oppong Asamoah,

Background: The increasing trends in cesarean delivery are globally acknowledged. However, in many low-resource countries, socioeconomic disparities have created a pattern of underuse and overuse among lower and higher socioeconomic groups. The impact of rising cesarean delivery rates on neonatal survival is also unclear.Objective: To examine cesarean delivery and its ... Read more >>

Glob Health Action (Global health action)
[2020, 13(1):1748403]

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Implementation of the INTERGROWTH-21st gestational dating and fetal and newborn growth standards in Nairobi, Kenya: women's experiences with ultrasound and newborn assessment.

Rachel M Jones, Linda Vesel, Grace Kimenju, Teresa Ogolla, Meghan Munson, Sarah Little, Sathyanath Rajasekharan, Mary Nell Wegner, Ana Langer, Nicholas Pearson,

BACKGROUND:In order to make further gains in preventing newborn deaths, effective interventions are needed. Ultrasounds and newborn anthropometry are proven interventions to identify preterm birth complications, the leading cause of newborn deaths. The INTERGROWTH-21st global gestational dating and fetal and newborn growth standards prescribe optimal growth in any population. Jacaranda ... Read more >>

Glob Health Action (Global health action)
[2020, 13(1):1770967]

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Colostrum fails to prevent bovine/camelid neonatal neutrophil damage from AFB1.

Sajad Najafi, Gholamreza Mohammadi, Mehrdad Mohri, Saman Hosseinkhani, Jalil Mehrzad,

Exposure to environmental toxicants that affect the immune system and overall health of many mammals is mostly unavoidable. One of the more common substances is the mycotoxins, especially carcinogenic aflatoxin (AF)B1 which also causes immune suppression/dysregulation in exposed hosts. The present study analyzed the effects of naturally occurring levels of ... Read more >>

J Immunotoxicol (Journal of immunotoxicology)
[2020, 17(1):43-50]

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Adding video-debriefing to Helping-Babies-Breathe training enhanced retention of neonatal resuscitation knowledge and skills among health workers in Uganda: a cluster randomized trial.

Beatrice Odongkara, Thorkild Tylleskär, Nicola Pejovic, Vincentina Achora, David Mukunya, Grace Ndeezi, James K Tumwine, Victoria Nankabirwa,

BACKGROUND:Skilled birth attendants must be competent to provide prompt resuscitation to save newborn lives at birth. Both knowledge and skills (competence) decline with time after training but the optimal duration for refresher training among frontline-skilled birth attendants in low-resource settings is unknown. OBJECTIVES:We assessed the effect of an innovative Helping-Babies-Breathe ... Read more >>

Glob Health Action (Global health action)
[2020, 13(1):1743496]

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Maternal-neonatal listeriosis.

Caroline Charlier, Olivier Disson, Marc Lecuit,

Listeriosis is a rare and severe foodborne infection caused by Listeria monocytogenes. It manifests as septicemia, neurolisteriosis, and maternal-fetal infection. In pregnancy, it may cause maternal fever, premature delivery, fetal loss, neonatal systemic and central nervous system infections. Maternal listeriosis is mostly reported during the 2nd and 3rd trimester of ... Read more >>

Virulence (Virulence)
[2020, 11(1):391-397]

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Women's development group leaders' promotion of maternal, neonatal and child health care in Ethiopia: a cross-sectional study.

Fisseha Ashebir, Araya Abrha Medhanyie, Afework Mulugeta, Lars Åke Persson, Della Berhanu,

BACKGROUND:Women's development group leaders are volunteer community health workers in Ethiopia who, among other duties, promote health and prevention of diseases. They link and extend essential health services from health posts to households. OBJECTIVE:To assess the characteristics, knowledge, and practice of women's development group leaders in the field of maternal, ... Read more >>

Glob Health Action (Global health action)
[2020, 13(1):1748845]

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A de novo CACNA1D missense mutation in a patient with congenital hyperinsulinism, primary hyperaldosteronism and hypotonia.

María Carmen De Mingo Alemany, Luis Mifsud Grau, Francisca Moreno Macián, Belén Ferrer Lorente, Sara León Cariñena,

Congenital hyperinsulinemic hypoglycemia is the most frequent cause of persistent and recurrent hypoglycemia in the first years of life and in many patients rare genetic variants can be identified. Recently a case of congenital hyperinsulinemic hypoglycemia and a severe neurodevelopmental syndrome due to a mutation in the voltage-gated Cav1.3 Ca2+ ... Read more >>

Channels (Austin) (Channels (Austin, Tex.))
[2020, 14(1):175-180]

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Exploring the perceptions, practices and challenges to maternal and newborn health care among the underprivileged teagarden community in Bangladesh: a qualitative study.

Animesh Biswas, Sathyanarayan Doraiswamy, Abu Sayeed Md Abdullah, Nabila Hossain Purno, Fazlur Rahman, M A Halim,

Poor health care-seeking behaviour, access to services and availability of service delivery have implications for the health of the community. This study explored the perceptions, practices and challenges related to maternal and neonatal care in the teagarden community in Bangladesh. The study also identified service gaps and problems prevalent in ... Read more >>

Sex Reprod Health Matters (Sexual and reproductive health matters)
[2020, 28(1):1758443]

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Apigenin-7-O-β-d-(6″-p-coumaroyl)-glucopyranoside reduces myocardial ischaemia/reperfusion injury in an experimental model via regulating the inflammation response.

Wei Quan, Shanbo Ma, Yanrong Zhu, Qing Shao, Jixing Hou, Xiaoqiang Li,

Context: Traditionally, Clematis tangutica Korsh. (Ranunculaceae) is used as a Tibetan herb for treating indigestion and blood stasis in China. Recently, a flavonoid glycoside, apigenin-7-O-β-d-(6″-p-coumaroyl)-glucopyranoside (APG), was isolated from the whole plant of C. tangutica.Objective: To investigate the cardioprotective effects of APG against myocardial ischaemia/reperfusion injury (MI/RI) and the possible ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2020, 58(1):80-88]

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Circular RNA cZNF292 silence alleviates OGD/R-induced injury through up-regulation of miR-22 in rat neural stem cells (NSCs).

Yaqin Cao, Hui Liu, Jun Zhang, Yubin Dong,

Background: Hypoxic-ischaemic encephalopathy (HIE) is a prevailing severe brain damage disease in newborns, and caused by perinatal asphyxia cerebral ischaemia and reperfusion. Here, we investigated the role of cZNF292 in oxygen-glucose deprivation/reperfusion (OGD/R)-induced neural stem cells (NSCs) injury, and explored the underlying molecular mechanism.Methods: Before NSCs were subjected to OGD/R ... Read more >>

Artif Cells Nanomed Biotechnol (Artificial cells, nanomedicine, and biotechnology)
[2020, 48(1):594-601]

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Epidemiology of neonatal sepsis caused by multidrug resistant pathogens in a neonatal intensive care unit level 3.

Devleta Hadžić, Fahrija Skokić, Selmira Brkić, Amina Saračević, Delila Softić, Dženana Softić,

Aim Steady progress in intensive treatment worldwide has increased the survival of immature neonates, but with multiple invasive procedures, which have increased the risk of infection, thus the bacterial resistance to antibiotics. The aim of this study was to analyse the epidemiology of multidrug resistance pathogens as causative agents of ... Read more >>

Med Glas (Zenica) (Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina)
[2020, 17(2):]

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The pathophysiological changes associated with neonatal death of cloned pigs.

Zheng Ao, Ting Gu, Huaxing Zhao, Junsong Shi, Enqin Zheng, Gengyuan Cai, Zhenfang Wu, Zicong Li,

Cloned pigs generated by the somatic cell transfer nuclear (SCNT) technique are highly valuable for agriculture, biomedicine, and life sciences. However, the neonatal mortality rate of cloned pigs is very high. The reasons causing the massive loss of cloned pigs during their neonatal ages are unclear. In the present study, ... Read more >>

Reproduction (Reproduction (Cambridge, England))
[2020, 160(2):193-203]

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Maternal Poppy Seed Tea Ingestion and Ensuing Neonatal Abstinence Syndrome.

Melissa Rae Garcia, Madeleine J Swortwood, Christine Nicole Aune, Kaashif Aqeeb Ahmad,

The incidence of neonatal abstinence syndrome has been rising in the USA. Nonpharmacological treatments resulting in similar withdrawal states in the newborn have also been described. We report an infant with neonatal abstinence syndrome born to a mother with daily poppy seed tea ingestion for the self-treatment of nausea. A ... Read more >>

Neonatology (Neonatology)
[2020, :1-3]

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Neonatal Mortality Burden and Trends in UNHCR Refugee Camps, 2006-2017: A Retrospective Analysis

Hannah Tappis, Marwa Ramadan, Josep Vargas, Vincent Kahi, Heiko Hering, Catrin Schulte-Hillen, Paul Spiegel,

Abstract Objective: To examine neonatal mortality burden and trends in refugee camps between 2006 and 2017. Methods : Refugee population and mortality data were exported from the United Nations High Commissioner (UNHCR) Health Information System (HIS) database. Tableau was used to export the data. Stata was used for data cleaning ... Read more >>

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Time to positive blood culture in early onset neonatal sepsis: A retrospective clinical study and review of the literature.

Lucinda Marks, Koert de Waal, John K Ferguson,

AIM:Neonatal early onset sepsis (EOS) is a low-incidence, high-risk disease which has prompted significant overtreatment with antibiotics for the standard duration of 48 h. The aims of this study were to determine whether blood cultures collected from term and late preterm neonates for EOS would return a positive result for pathogenic ... Read more >>

J Paediatr Child Health (Journal of paediatrics and child health)
[2020, :]

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MiR-96-5p alleviates inflammatory responses by targeting NAMPT and regulating the NF-κB pathway in neonatal sepsis.

Xueli Chen, Ying Chen, Li Dai, Na Wang,

Neonatal septicemia is a serious infectious disease in the neonatal period. MicroRNAs (miRNAs) have been reported to participate in the inflammatory responses in neonatal sepsis. The aim of the present study was to explore the effects and molecular mechanism of miR-96-5p on regulating the inflammatory responses in neonatal sepsis. MiR-96-5p ... Read more >>

Biosci. Rep. (Bioscience reports)
[2020, 40(7):]

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Human milk oligosaccharides and their association with late-onset neonatal sepsis in Peruvian very-low-birth-weight infants.

Victor D Torres Roldan, Meritxell Urtecho S, Julia Gupta, Chloe Yonemitsu, Cesar P Cárcamo, Lars Bode, Theresa J Ochoa,

BACKGROUND:Oligosaccharides are the third most abundant component in human milk. They are a potential protective agent against neonatal sepsis. OBJECTIVES:We aimed to explore the association between human milk oligosaccharides (HMOs) and late-onset sepsis in very-low-birth-weight infants, and to describe the composition and characteristics of HMOs in Peruvian mothers of these ... Read more >>

Am. J. Clin. Nutr. (The American journal of clinical nutrition)
[2020, 112(1):106-112]

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Estimated fetal weight and severe neonatal outcomes in preterm prelabor rupture of membranes.

Jose R Duncan, Katherine M Dorsett, Michael M Aziz, Zoran Bursac, Mario A Cleves, Ajay J Talati, Mauro H Schenone, Nornan L Meyer, Giancarlo Mari,

Objectives Our aim was to study the association of clinical variables obtainable before delivery for severe neonatal outcomes (SNO) and develop a clinical tool to calculate the prediction probability of SNO in preterm prelabor rupture of membranes (PPROM). Methods This was a prospective study from October 2015 to May 2018. ... Read more >>

J Perinat Med (Journal of perinatal medicine)
[2020, :]

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Breastfeeding and Formula Selection in Neonatal Abstinence Syndrome.

Amy L Lembeck, Deborah Tuttle, Robert Locke, Laura Lawler, Pamela Jimenez, Amy Mackley, David A Paul,

OBJECTIVE: This study aimed to determine if formula selection, low lactose versus standard term formula, has an effect on outcomes with a comparison to breastfed infants. STUDY DESIGN: Retrospective cohort study of neonates ≥35 weeks gestation born with Neonatal Abstinence Syndrome (NAS) was conducted from July 2014 to November 2016. Primary outcomes ... Read more >>

Am J Perinatol (American journal of perinatology)
[2020, :]

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A combined effect of anti-HPA-1a and anti-HLA Class I in pregnancy?

Jesper Dahl, Bjørn Skogen, Mette Kjaer, Anne Husebekk, Jens Kjeldsen-Kragh, Heidi Tiller,

BACKGROUND:Maternal anti-human leukocyte antigen (HLA) Class I is commonly detected alongside anti-human platelet antigen (HPA)-1a in fetal and neonatal alloimmune thrombocytopenia (FNAIT). Little is known regarding whether the presence of anti-HLA Class I may exert an additive effect on the risk and severity of FNAIT. METHODS AND MATERIALS:We reanalyzed samples ... Read more >>

Transfusion (Transfusion)
[2020, :]

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Predictors of neonatal sepsis in public referral hospitals, Northwest Ethiopia: A case control study.

Tadesse Yirga Akalu, Bereket Gebremichael, Kalkidan Wondwossen Desta, Yared Asmare Aynalem, Wondimeneh Shibabaw Shiferaw, Yoseph Merkeb Alamneh,

BACKGROUND:Despite remarkable progress in the reduction of death in under-five children, neonatal mortality has shown little or no concomitant reduction globally. It is also one of the most common causes of neonatal death in Ethiopia. Little is known on predictors of neonatal sepsis. Risk based screening and commencement of treatment ... Read more >>

PLoS ONE (PLoS ONE)
[2020, 15(6):e0234472]

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Early neonatal sepsis and meningitis caused by Elizabethkingia meningoseptica in Saudi Arabia.

Ashwaq I Barnawi, Faisal N Kordy, Ohoud K Almuwallad, Khloud A Kassarah,

Elizabethkingia meningoseptica (E. meningoseptica ) are Gram-negative bacteria commonly associated with nosocomial infections in neonates. This is a case study of E. meningoseptica, presented as meningitis and sepsis in a term baby. The female infant was born by vaginal delivery at 37 weeks gestational age. The case was peculiar because ... Read more >>

Saudi Med J (Saudi medical journal)
[2020, 41(7):753-756]

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Apgar Score and Risk of Neonatal Death among Preterm Infants.

Sven Cnattingius, Stefan Johansson, Neda Razaz,

BACKGROUND:Gestational age is the major determinant of neonatal death (death within the first 28 days of life) in preterm infants. The joint effect of gestational age and Apgar score on the risk of neonatal death is unknown. METHODS:Using data from the Swedish Medical Birth Register, we identified 113,300 preterm infants ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2020, 383(1):49-57]

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Head circumference in infants with non-opiate-induced neonatal abstinence syndrome.

Daisaku Morimoto, Yosuke Washio, Kazuki Hatayama, Tomoka Okamura, Hirokazu Watanabe, Junko Yoshimoto, Hirokazu Tsukahara,

CNS Spectr (CNS spectrums)
[2020, :1-17]

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