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Neonatal Jaundice

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Predictors of outcome in childhood Plasmodium falciparum malaria.

Harsita Patel, Claire Dunican, Aubrey J Cunnington,

Plasmodium falciparum malaria is classified as either uncomplicated or severe, determining clinical management and providing a framework for understanding pathogenesis. Severe malaria in children is defined by the presence of one or more features associated with adverse outcome, but there is wide variation in the predictive value of these features. ... Read more >>

Virulence (Virulence)
[2020, 11(1):199-221]

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Management strategies of neonatal jaundice during the coronavirus disease 2019 outbreak.

Xiao-Lu Ma, Zheng Chen, Jia-Jun Zhu, Xiao-Xia Shen, Ming-Yuan Wu, Li-Ping Shi, Li-Zhong Du, Jun-Fen Fu, Qiang Shu,

The outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV) has become a most challenging health emergency. Owing to rigorous quarantine and control measures taken in China, routine neonatal health surveillance and follow-up have become challenging. Without follow-up surveillance, some rapid and progressive newborn diseases, such as bilirubin encephalopathy, may be ... Read more >>

World J Pediatr (World journal of pediatrics : WJP)
[0, :1-4]

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Determinants of excessive weight loss in breastfed full-term newborns at a baby-friendly hospital: a retrospective cohort study.

Yasuhiro Miyoshi, Hideyo Suenaga, Mikihiro Aoki, Shigeki Tanaka,

BACKGROUND:Excessive weight loss in newborns is associated with neonatal complications such as jaundice and dehydration, which cause renal failure, thrombosis, hypovolemic shock, and seizures. The identification of the risk factors for excessive weight loss will help to discover preventive measures. The aim of this study was to determine the factors ... Read more >>

Int Breastfeed J (International Breastfeeding Journal)
[2020, 15(1):19]

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[Incidence and risk factors for severe hyperbilirubinemia in term neonates].

Asa Unnur Bergmann, Thordur Thorkelsson,

INTRODUCTION:Newborn jaundice is caused by increased levels of bilirubin in the blood of the newborn during the first days after birth. Generally, neonatal jaundice does not need to be treated, however, if the blood bilirubin concentration becomes too high, it can cause neurological damage. Due to the prevalence of neonatal ... Read more >>

Laeknabladid (Laeknabladid)
[2020, 106(3):139-143]

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Assessing quality of newborn care at district facilities in Malawi.

Kondwani Kawaza, Mai-Lei Woo Kinshella, Tamanda Hiwa, Jenala Njirammadzi, Mwai Banda, Marianne Vidler, Laura Newberry, Alinane Linda Nyondo-Mipando, Queen Dube, Elizabeth Molyneux, David M Goldfarb,

BACKGROUND:Malawi is celebrated as one of the few countries in sub-Saharan Africa to meet the Millennium Development Goal of reducing under-5 mortality by two-thirds between 1990 and 2015. However, within this age range neonatal mortality rates are the slowest to decline, even though rates of facility births are increasing. Examining ... Read more >>

BMC Health Serv Res (BMC health services research)
[2020, 20(1):227]

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Efficacy of zinc sulfate on indirect hyperbilirubinemia in premature infants admitted to neonatal intensive care unit: a double-blind, randomized clinical trial.

Gholamreza Faal, Hoda Khatib Masjedi, Gholamreza Sharifzadeh, Zahra Kiani,

BACKGROUND:Hyperbilirubinemia is a common neonatal problem. Studies conducted on the effectiveness of zinc salts on serum indirect bilirubin levels in newborns have yielded different results, all calling for further research. This study aimed to determine the effect of oral zinc sulfate on indirect hyperbilirubinemia in preterm infants admitted to the ... Read more >>

BMC Pediatr (BMC pediatrics)
[2020, 20(1):130]

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Pattern of Cerebral Palsy Among Sudanese Children Less Than 15 Years of Age.

Karimeldin Salih,

BACKGROUND:Cerebral palsy (CP) is a non-progressive, everlasting neurological disorder of movement, posture, and physical activities, with a prevalence of 2.2-3.3/1,000. CP is a condition that occurs globally, with a similar prevalence in both developed and undeveloped countries. However, the etiology differs according to the socioeconomic status of the countries. The ... Read more >>

Cureus (Cureus)
[2020, 12(3):e7232]

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Risk factors for pregnancy outcomes in type 1 and type 2 diabetes.

Jas-Mine Seah, Ning Mao Kam, Lydia Wong, Cara Tanner, Alexis Shub, Elif I Ekinci, Christine Houlihan,

OBJECTIVE:Our aim was to explore differences in pregnancy outcomes between women with type 1 and type 2 diabetes, and healthy controls, and to examine the relationships between potential adverse risk factors and pregnancy outcomes in this cohort of women. STUDY DESIGN AND METHODS:This is a 10 year retrospective study of ... Read more >>

Intern Med J (Internal medicine journal)
[2020, :]

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Efficacy of oral agar in management of indirect hyperbilirubinemia in full-term neonates.

Safwat M Abdel-Aziz Ali, Shereen Mansour Galal, Shaban M Sror, Omima Hussein, Abd-El-Haseeb Osman Abd-El-Haseeb Ahmed, Enas A Hamed,

Aim: This prospective randomized case control study aimed to investigate effect of oral agar administration in reducing total serum bilirubin (TSB) levels in full-term neonates with jaundice in comparison with control.Materials and methods: One hundred sixty full-term neonates were enrolled with TSB 10-19 mg/dl at first week of age from Assiut ... Read more >>

J. Matern. Fetal. Neonatal. Med. (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2020, :1-6]

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Patterns of neurobehavioral functioning in school-aged survivors of neonatal jaundice and hypoxic-ischemic encephalopathy in Kilifi, Kenya: A cross-sectional study

Dorcas Magai, Charles Newton, Paul Mwangi, Hans Koot, Amina Abubakar,

Background: Studies in high-income countries have reported that school-aged children who survive neonatal jaundice (NNJ) and hypoxic-ischemic encephalopathy (HIE) develop long-term neurocognitive problems. However, less is known about the patterns of functioning in school-aged survivors of NNJ and HIE in sub-Saharan Africa. This study examined patterns of functioning in school-aged ... Read more >>

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Letter to the Editor on the original article "Efficacy of double versus single phototherapy in treatment of neonatal jaundice: a meta-analysis" by MA Nizam et al.

Sindhu Sivanandan, Anu Thukral,

Eur. J. Pediatr. (European journal of pediatrics)
[2020, :]

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Maternal Instruction on Neonatal Jaundice: What Can we Learn from the Stop Kernicterus in Nigeria (SKIN) Experience?

Jon F Watchko,

J. Pediatr. (The Journal of pediatrics)
[2020, :]

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Effect of skin-to-skin contact at birth on early neonatal hospitalization.

Sergio Agudelo, Diana Díaz, María José Maldonado, Eduardo Acuña, Daniel Mainero, Oman Pérez, Laura Pérez, Carlos Molina,

BACKGROUND:Skin-to-skin contact (SCC) at birth has a positive impact on breastfeeding indicators and physiological stabilization at birth. On the other hand, globally and in Colombia, morbidity and mortality have increased in intermediate- and low-risk infants. The aim of the study was to assess the effect of immediate skin-to-skin contact, compared ... Read more >>

Early Hum. Dev. (Early human development)
[2020, 144:105020]

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The relationship between umbilical cord blood vitamin A levels and late preterm infant morbidities: A prospective cohort study

Tian-Ming Yuan, En-Fu Tao, Cai-E Chen, Yun-Qin Chen, Lin-Yan Cai,

<title>Abstract</title> <p> <bold>Background:</bold> Low plasma vitamin A levels increases the risk of neonates’ morbidity. However, the relationship between umbilical cord blood (UCB) vitamin A levels and late-preterm infant (LPI) consequences is inconclusive. Herein, we attempted to clarify the association between UCB vitamin A levels and LPI morbidities.<bold>Methods:</bold> We ... Read more >>

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Prevalence of and mothers' knowledge, attitude and practice towards glucose-6-phosphate dehydrogenase deficiency among neonates with jaundice: a cross-sectional study.

Zeinab A Kasemy, Wael A Bahbah, Sally M El Hefnawy, Safa H Alkalash,

BACKGROUND:Neonatal jaundice (NNJ) is a frequent complication of glucose-6-phosphate dehydrogenase (G6PD) deficiency. OBJECTIVES:To estimate the prevalence of G6PD deficiency among neonates with jaundice and to assess mothers' perception towards G6PD and NNJ. METHODS:A cross-sectional study was carried out on 487 ethnic Egyptian neonates with indirect hyperbilirubinaemia from June 2018 to ... Read more >>

BMJ Open (BMJ open)
[2020, 10(2):e034079]

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Management strategies of neonatal jaundice during the coronavirus disease 2019 outbreak.

Xiao-Lu Ma, Zheng Chen, Jia-Jun Zhu, Xiao-Xia Shen, Ming-Yuan Wu, Li-Ping Shi, Li-Zhong Du, Jun-Fen Fu, Qiang Shu,

The outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV) has become a most challenging health emergency. Owing to rigorous quarantine and control measures taken in China, routine neonatal health surveillance and follow-up have become challenging. Without follow-up surveillance, some rapid and progressive newborn diseases, such as bilirubin encephalopathy, may be ... Read more >>

World J Pediatr (World journal of pediatrics : WJP)
[2020, :]

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Maternal Instruction About Jaundice and the Incidence of Acute Bilirubin Encephalopathy in Nigeria.

Richard P Wennberg, Stephen Oguche, Zainab Imam, Zubaida L Farouk, Isa Abdulkadir, Paul D Sampson, Tina M Slusher, Fidelia Bode-Thomas, Bose O Toma, Christopher S Yilgwan, David Shwe, Akinyemi O Ofakunrin, Udochukwu M Diala, Chris Isichei, Victor Pam, Zuwaira Hassan, Shehu U Abdullahi, Fatima Usman, Binta W Jibir, Idris Y Mohammed, Hadiza A Usman, Muhammed Abdusalam, Aisha Kuliya-Gwarzo, Fatima I Tsiga-Ahmad, Laila Umar, William N Ogala, Fatimatu Abdullahi, Laila Hassan, Saratu Purdue, Troy Lund, Carlos D Coda-Zabetta,

OBJECTIVE:To evaluate whether teaching mothers about neonatal jaundice will decrease the incidence of acute bilirubin encephalopathy among infants admitted for jaundice. STUDY DESIGN:This was a multicenter, before-after and cross-sectional study. Baseline incidences of encephalopathy were obtained at 4 collaborating medical centers between January 2014 and May 2015 (Phase 1). Structured ... Read more >>

J. Pediatr. (The Journal of pediatrics)
[2020, :]

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Smartphone screening for neonatal jaundice via ambient-subtracted sclera chromaticity.

Felix Outlaw, Miranda Nixon, Oluwatobiloba Odeyemi, Lindsay W MacDonald, Judith Meek, Terence S Leung,

Jaundice is a major cause of mortality and morbidity in the newborn. Globally, early identification and home monitoring are significant challenges in reducing the incidence of jaundice-related neurological damage. Smartphone cameras are promising as colour-based screening tools as they are low-cost, objective and ubiquitous. We propose a novel smartphone method ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0216970]

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The relationship between hyperbilirubinemia and the promoter region and first exon of UGT1A1 gene polymorphisms in Vietnamese newborns.

Tien-Thanh Nguyen, Wei Zhao, Xi Yang, Dan-Ni Zhong,

BACKGROUND:To investigate the relationship between unexplained indirect hyperbilirubinemia of Vietnamese newborns and the polymorphism of the promoter TATA box and exon 1 of bilirubin uridine diphosphate glucuronosyltransferase (UGT1A1) gene. METHODS:A total of 149 neonates were divided into the hyperbilirubinemia group (n = 99) and control group (n = 50). The gene polymorphisms of UGT1A1 ... Read more >>

Pediatr. Res. (Pediatric research)
[2020, :]

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Addressing the Challenges to Diagnose Neonatal Hemolytic Anemia's Aetiologies in Low Ressources Countries: A Case Report.

Lydie Ocini Ngolet, Josue Simo Louokdom, Nelly Guembo, Ocko Ngokaba Thibault,

Background. The diagnosis of neonatal hemolysis is an easy exercise. However, the diagnosis of its etiology can be very challenging especially in low ressources countries where laboratory capacities are limited. We report the case of hemolytic anemia episodes that started in the neonatal period, for which the trigger factor, infectious ... Read more >>

Case Rep Hematol (Case reports in hematology)
[2020, 2020:3247127]

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Well Neonate Due For Discharge In Low Resource Setting Must Be Screened For Significant Hyperbilirubinemia

Yaser Abdallah, Nasuna Carolyn, Karamagi Charles, Mugalu Jamiru,

<title>Abstract</title> <p> Introduction: Due to inadequacy of postnatal care in low resource settings, neonates with significant hyperbilirubinemia are likely to be discharged home only to develop complications of hyperbilirubinemia. Objective: To determine the prevalence of significant hyperbilirubinemia among well neonates due for discharged, factors associated with it and ... Read more >>

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Etiology and therapeutic management of neonatal jaundice in Iran: a systematic review and meta-analysis.

Yadollah Zahed Pasha, Shaghayegh Alizadeh-Tabari, Ermia Zahed Pasha, Mohammad Zamani,

BACKGROUND:Jaundice is a life-threatening disorder in the neonates. In the present study, we aimed to assess systematically available evidence on causes and management of jaundice in Iranian newborn patients. METHODS:We searched the databases of PubMed, Web of Sciences, Scopus and Google Scholar for English articles published since inception until May ... Read more >>

World J Pediatr (World Journal of Pediatrics)
[2020, :]

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Pregnancy outcomes in association with placental histopathology in pregnancies complicated by macrosomia in diabetic vs. non-diabetic women.

Ilia Kleiner, Shai Ram, Michal Kovo, Letizia Schreiber, Elad Barber, Michal Levy, Nataly Fainstein, Jacob Bar, Eran Weiner,

OBJECTIVE:We aimed to compare pregnancy outcomes in association with placental pathology in pregnancies complicated by macrosomia in diabetic vs. non-diabetic women. STUDY DESIGN:Pregnancies complicated by macrosomia (≥4000gr) were included. Pregnancy and delivery characteristics, neonatal outcomes and placental histopathology reports were compared between macrosomia in diabetic [pre-gestational or Gestational Diabetes Mellitus ... Read more >>

Eur. J. Obstet. Gynecol. Reprod. Biol. (European journal of obstetrics, gynecology, and reproductive biology)
[2020, 248:24-29]

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Evaluation of Maternal Risk Factors in Neonatal Hyperbilirubinemia.

Hassan Boskabadi, Forough Rakhshanizadeh, Maryam Zakerihamidi,

BACKGROUND:Diagnosis and timely treatment of neonatal jaundice and prevention of dangerous side effects of pathologic neonatal jaundice remain a serious debate. The first step in prevention of jaundice is the identification of predisposing factors. The present study aims to systematically review the maternal risk factors of neonatal hyperbilirubinemia. METHODS:For this ... Read more >>

Arch Iran Med (Archives of Iranian medicine)
[2020, 23(2):128-140]

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Is Lower Vitamin D Level Associated with Increased Risk of Neonatal Sepsis? A Prospective Cohort Study.

Chinmay Kumar Behera, Jagdish Prasad Sahoo, Saumya Darshana Patra, Pratap Kumar Jena,

OBJECTIVE:To evaluate the effect of maternal/ neonatal vitamin D levels on culture positive neonatal sepsis. METHODS:This prospective cohort study was conducted in the NICU of a tertiary care teaching hospital in Odisha, Eastern India from January 2015 through December 2016. Forty (40) neonates with culture positive sepsis were included in ... Read more >>

Indian J Pediatr (Indian journal of pediatrics)
[2020, :]

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