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Predictive ability of motion sickness susceptibility questionnaire for seasickness individual difference in Chinese military personnel

Yiling Cai, Leilei Pan, Ruirui Qi, Shuifeng Xiao, Yuqi Mao, Yang Su, Rong Xu, Li Gui, Junqin Wang,

<title>Abstract</title> <p> Background Motion sickness susceptibility questionnaire (MSSQ) has been widely used for assessing individual differences in motion sickness. The present study tried to investigate its efficacy for predicting seasickness susceptible (SUS) and insusceptible (INSUS) subjects among Chinese military personnel. Methods Two cohorts of young male army volunteers ... Read more >>

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Inner ear AVP-V2R-AQP2 signaling pathway is involved in the induction of motion sickness.

Li-Hua Xu, Yao Yang, Hong-Xia Liu, Shui-Feng Xiao, Wen-Xia Qiu, Jin-Xing Wang, Chen-Chen Zhao, Yuan-Hong Gui, Gui-Zhu Liu, Bin Peng, Xia Li, Guo-Hua Wang, Xin Zhou, Zheng-Lin Jiang,

It has been identified that arginine vasopressin (AVP), AVP receptor 2 (V2R) and the aquaporin 2 (AQP2) signaling pathway in the inner ear play important roles in hearing and balance functions through regulating the endolymph equilibrium; however, the contributions of this signaling pathway to the development of motion sickness are ... Read more >>

J. Pharmacol. Exp. Ther. (The Journal of pharmacology and experimental therapeutics)
[2020, :]

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Imbalance, motion sensitivity, anxiety and handicap in vestibular migraine and migraine only patients.

Birgul Balcı, Gülden Akdal,

OBJECTIVE:The aim of this study is to compare the balance ability, anxiety level and motion sickness susceptibility in Vestibular Migraine (VM) patients, migraineurs without history of vertigo (Migraine-only, MO) and healthy controls (HC). We tested the hypothesis that VM patients have worse balance performance and higher anxiety level and motion ... Read more >>

Auris Nasus Larynx (Auris, nasus, larynx)
[2020, :]

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The effects of meclizine on motion sickness revisited.

Tobias Wibble, Johanna Engström, Luca Verrecchia, Tony Pansell,

AIMS:Antihistamines make up the first line of treatments against motion-sickness. Still, their efficacy and specific mechanism have come into question. The aim of this study was to investigate the effect of meclizine on motion-sensitivity. METHODS:This study was carried out as a triple-blinded randomized trial involving 12 healthy subjects who were ... Read more >>

Br J Clin Pharmacol (British journal of clinical pharmacology)
[2020, :]

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Netupitant/palonosetron (NEPA) and dexamethasone for prevention of emesis in breast cancer patients receiving adjuvant anthracycline plus cyclophosphamide: a multi-cycle, phase II study.

Roberta Caputo, Marina Elena Cazzaniga, Andrea Sbrana, Rosalba Torrisi, Ida Paris, Monica Giordano, Vincenzo Montesarchio, Valentina Guarneri, Laura Amaducci, Domenico Bilancia, Giuseppina Cilenti, Alessandra Fabi, Elena Collovà, Alessio Schirone, Erminio Bonizzoni, Luigi Celio, Sabino De Placido, Michelino De Laurentiis,

BACKGROUND:NEPA is an oral fixed-dose combination of netupitant, a new highly selective neurokinin-1 receptor antagonist, and palonosetron. This study was conducted to evaluate whether the efficacy of NEPA against chemotherapy-induced nausea and vomiting (CINV) in cycle 1 would be maintained over subsequent chemotherapy cycles in breast cancer patients receiving adjuvant ... Read more >>

BMC Cancer (BMC cancer)
[2020, 20(1):232]

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Editorial: Role of Inner Ear in Self and Environment Perception.

Christophe Lopez, Michel Toupet, Christian van Nechel, Alexis Bozorg Grayeli,

Front Neurol (Frontiers in neurology)
[2020, 11:22]

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Claire Fraser, RN, MD, OMG: history of medicine in the Outlander novels and series.

Stephen J. Greenberg,

This article discusses how Claire Randall, RN, MD, the fictional protagonist of Diana Gabaldon’s widely popular Outlander series, uses her knowledge of twentieth century medicine in her adventures in eighteenth century Scotland, France, and America. ... Read more >>

J Med Libr Assoc (Journal of the Medical Library Association : JMLA)
[2020, 108(2):310-313]

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Visual Vertigo, Motion Sickness, and Disorientation in Vehicles.

A M Bronstein, J F Golding, M A Gresty,

Environmental circumstances that result in ambiguity or conflict with the patterns of sensory stimulation may adversely affect the vestibular system. The effect of this conflict in sensory information may be dizziness, a sense of imbalance, nausea, and motion sickness sometimes even to seemingly minor daily head movement activities. In some, ... Read more >>

Semin Neurol (Seminars in neurology)
[2020, 40(1):116-129]

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Knowing what's coming: Anticipatory audio cues can mitigate motion sickness.

Ouren X Kuiper, Jelte E Bos, Cyriel Diels, Eike A Schmidt,

Being able to anticipate upcoming motion is known to potentially mitigate sickness resulting from provocative motion. We investigated whether auditory cues could increase anticipation and subsequently reduce motion sickness. Participants (N = 20) were exposed on a sled on a rail track to two 15-min conditions. Both were identical in terms of ... Read more >>

Appl Ergon (Applied ergonomics)
[2020, 85:103068]

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Motion Sickness Predictors in College Students and Their First Experience Sailing at Sea.

Xinchen Zhang, Yeqing Sun,

INTRODUCTION: Individual motion sickness susceptibility can be rapidly estimated by the motion sickness susceptibility questionnaire (MSSQ), but its stability is affected by various factors. The purpose of this study was to investigate the involved predictive factors of motion sickness screened with uniform samples of Chinese college students and to verify ... Read more >>

Aerosp Med Hum Perform (Aerospace medicine and human performance)
[2020, 91(2):71-78]

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Understanding vestibular-related physiological functions could provide clues on adapting to a new gravitational environment.

Hironobu Morita, Hiroshi Kaji, Yoichi Ueta, Chikara Abe,

The peripheral vestibular organs are sensors for linear acceleration (gravity and head tilt) and rotation. Further, they regulate various body functions, including body stability, ocular movement, autonomic nerve activity, arterial pressure, body temperature, and muscle and bone metabolism. The gravitational environment influences these functions given the highly plastic responsiveness of ... Read more >>

J Physiol Sci (The journal of physiological sciences : JPS)
[2020, 70(1):17]

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[Virtual reality exposure therapy for post-traumatic stress disorders, obsessive-compulsive disorders and anxiety disorders: Indications, added value and limitations].

M Lognoul, J Nasello, J-M Triffaux,

The exposure in cognitive behavioral therapy (CBT) is a well-known intervention, widely investigated in scientific research. Several studies have shown the benefits of this intervention in the treatment of anxiety disorders, obsessive-compulsive disorders (OCD) and post-traumatic stress disorders (PTSD). The different exposure techniques are mainly based on the emotional processing ... Read more >>

Encephale (L'Encephale)
[2020, :]

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5-Hydroxytryptamine-3 Receptor Antagonist and Dexamethasone as Prophylaxis for Chemotherapy Induced Nausea and Vomiting during Moderately Emetic Chemotherapy for Solid Tumors: A Multicenter, Prospective, Observational Study

Koichi Goto, Reiko Matsui, Kenichi Suzuki, Tomomi Takiguchi, Makoto Nishio, Takeshi Koike, Toshinobu Hayashi, Takashi Seto, Yuki Kogure, Naoyuki Nogami, Kimiko Fujiwara, Hiroyasu Kaneda, Tomohiko Harada, Satoru Shimizu, Masashi Kimura, Hirotsugu Kenmotsu, Mototsugu Shimokawa,

<title>Abstract</title> <p> Background Patients receiving moderate emetic risk chemotherapy (MEC) occurs chemotherapy-induced nausea and vomiting (CINV) in 30–90%, however the optimal antiemetic treatment remains controversial. Methods In this multicenter, prospective, observational study of adults treated with MEC for various cancer types in Japan, We enrolled patients kept diaries ... Read more >>

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Assessing the Autonomic and Behavioral Effects of Passive Motion in Rats using Elevator Vertical Motion and Ferris-Wheel Rotation.

Francis A M Manno, Leilei Pan, Yuqi Mao, Yang Su, Sinai H C Manno, Shuk Han Cheng, Condon Lau, Yiling Cai,

The overall goal of this study is to assess the autonomic and behavioral effects of passive motion in rodents using the elevator vertical motion and Ferris-wheel rotation devices. These assays can help confirm the integrity and normal functioning of the autonomic nervous system. They are coupled to quantitative measures based ... Read more >>

J Vis Exp (Journal of visualized experiments : JoVE)
[2020, (156):]

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The brain-penetrating, orally bioavailable, ghrelin receptor agonist HM01 ameliorates motion-induced emesis in Suncus murinus (house musk shrew).

Longlong Tu, Zengbing Lu, Man P Ngan, Francis F Y Lam, Claudio Giuliano, Emanuela Lovati, Claudio Pietra, John A Rudd,

BACKGROUND AND PURPOSE:HM01, a novel, orally bioavailable, brain-penetrating agonist of ghrelin receptors, ameliorates emesis in Suncus murinus. This study compared HM01's activity against motion sickness with that of the less brain-penetrating ghrelin receptor agonist, HM02. EXPERIMENTAL APPROACH:The potential of HM01 and HM02 to relax isolated mesenteric arteries and to increase ... Read more >>

Br. J. Pharmacol. (British journal of pharmacology)
[2020, 177(7):1635-1650]

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Scopolamine, a toxin-induced experimental model used for research in Alzheimer's disease.

Win Ning Chen, Keng Yoon Yeong,

Scopolamine as a drug is often used to treat motion sickness. Derivatives of scopolamine have also found applications as antispasmodic drug among others. In neuroscience-related research, it is often used to induce cognitive disorders in experimental models as it is readily permeates the blood brain barrier. In the context of ... Read more >>

CNS Neurol Disord Drug Targets (CNS & neurological disorders drug targets)
[2020, :]

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Molecular classification of the placebo effect in nausea

Karin Meissner, Dominik Lutter, Christine von Toerne, Anja Haile, Stephen Woods, Verena Hoffmann, Uli Ohmayer, Stefanie Hauck, Matthias Tschöp,

ABSTRACT Numerous studies have shown that the mere expectation improvement can alleviate symptoms in various conditions. These ‘placebo effects’ often include reliable changes in central and peripheral organ systems. Here, we tested for the first time whether placebo effects can be monitored and predicted by plasma proteins. In a randomized ... Read more >>

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Horizontal and Vertical Distance Perception in Altered Gravity.

Gilles Clément, Angie Bukley, Nuno Loureiro, Louise Lindblad, Duarte Sousa, André Zandvilet,

The perception of the horizontal and vertical distances of a visual target to an observer was investigated in parabolic flight during alternating short periods of normal gravity (1 g). microgravity (0 g), and hypergravity (1.8 g). The methods used for obtaining absolute judgments of egocentric distance included verbal reports and visually directed motion ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):5471]

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Impact of Body Size Match to an Avatar on the Body Ownership Illusion and User's Subjective Experience.

So-Yeon Kim, Hyojin Park, Myeongul Jung, Kwanguk Kenny Kim,

The current study sought to investigate the effects of matching body movement and body size between an avatar and a participant on the body ownership illusion (BOI), the body size illusion, the sense of presence, simulator sickness, and emotional responses within an immersive virtual reality (IVR). Forty participants experienced their ... Read more >>

Cyberpsychol Behav Soc Netw (Cyberpsychology, behavior and social networking)
[2020, :]

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Concern of Photosensitive Seizures Evoked by 3D Video Displays or Virtual Reality Headsets in Children: Current Perspective.

Lawrence Tychsen, Liu Lin Thio,

This review assesses the risk of a photic-induced seizure in a child during viewing of 3D (binocular 3 dimensional, stereoscopic) movies or games, either on standard video displays or when wearing a virtual reality (VR) headset. Studies published by pediatric epilepsy experts emphasize the low risk of 3D viewing even ... Read more >>

Eye Brain (Eye and brain)
[2020, 12:45-48]

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Too Real to Be Virtual: Autonomic and EEG Responses to Extreme Stress Scenarios in Virtual Reality.

Kirill A. Fadeev, Alexey S. Smirnov, Olga P. Zhigalova, Polina S. Bazhina, Alexey V. Tumialis, Kirill S. Golokhvast,

The evolution of virtual reality (VR) technologies requires setting boundaries of its use. In this study, 3 female participants were experiencing VR scenarios with stressful content and their activity of the autonomic nervous system and EEG were recorded. It has been discovered that virtual reality can evoke acute stress reactions ... Read more >>

Behav Neurol (Behavioural Neurology)
[2020, 2020:]

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Pseudo-Sensation of Walking Generated by Passive Whole-Body Motions in Heave and Yaw Directions.

Tomohiro Amemiya, Michiteru Kitazaki, Yasushi Ikei,

Walking is an innate human behavior that propels the body forward. Recent studies have investigated the creation of a walking sensation wherein, the body neither moves nor is forced to move. However, it is unclear which whole-body motions effectively induce the sensation of walking. Here, we show that passive whole-body ... Read more >>

IEEE Trans Haptics (IEEE transactions on haptics)
[2020, 13(1):80-86]

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Mal de Debarquement Syndrome: A Rare Entity.

Shehzeen F Memon, Anosh Aslam Khan, Osama Mohiuddin, Shahzeb Ali Memon,

Mal de debarquement syndrome (MdDS) is a bizarre sensation of continued movement after the termination of motion. It is accompanied by disequilibrium, usually experienced after voyage or travel, however, it is not associated with vertigo. Although most cases resolve spontaneously, middle-aged women sometimes particularly experience protracted symptoms following an ocean cruise, with ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6837]

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Velocity storage: its multiple roles.

James R Lackner, Paul DiZio,

Our research described in this article was motivated by the puzzling finding of the Skylab M131 experiments: head movements made while rotating that are nauseogenic and disorienting on Earth are innocuous in a weightless, 0-g environment. We describe a series of parabolic flight experiments that directly addressed this puzzle and ... Read more >>

J. Neurophysiol. (Journal of neurophysiology)
[2020, 123(3):1206-1215]

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Normative Responses to Clinical Tests for Cervicogenic Dizziness: Clinical Cervical Torsion Test and Head-Neck Differentiation Test.

Julia Treleaven, Vladimir Joloud, Yoav Nevo, Clare Radcliffe, Mollie Ryder,

BACKGROUND:The clinical diagnosis of cervicogenic dizziness (CGD) is challenging because of a lack of sensitive and specific diagnostic tests. It is vital for clinicians to know normative responses to suggested clinical tests to help them develop the method and interpretation of these tests and maximize their diagnostic value for CGD. ... Read more >>

Phys Ther (Physical therapy)
[2020, 100(1):192-200]

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