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One-hour post-load glucose improves the prediction of cardiovascular events in the OPERA study.

Anni Saunajoki, Juha Auvinen, Aini Bloigu, Olavi Ukkola, Sirkka Keinänen-Kiukaanniemi, Markku Timonen,

<h4>Background</h4>To estimate the ability of fasting, 1-h, and 2-h post-load glucose to predict cardiovascular outcomes.<h4>Methods</h4>We examined a population-based study consisting of 977 middle-aged subjects who underwent an oral glucose tolerance test with glucose values measured at 0, 60, and 120 min. Participants were followed up to 24 years, and cardiovascular outcomes were ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):478-484]

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Infections in hematopoietic stem cell transplant patients admitted to Hematology intensive care unit: a single-center study.

Tuğba Barlas, Kamil İnci, Gulbin Aygencel, Melda Türkoğlu, Özlem Güzel Tunçcan, Ferda Can, Lale Aydın Kaynar, Zübeyde Nur Özkurt, Zeynep Arzu Yeğin, Münci Yağcı,

<h4>Objective</h4>The aim of this study was to investigate the data of HSCT patients who were admitted to our Hematology ICU due to infections or infectious complications.<h4>Materials and methods</h4>HSCT patients who were admitted to our Hematology ICU between 01 January 2014 and 01 September 2017 were analyzed retrospectively.<h4>Results</h4>62 HSCT patients were ... Read more >>

Hematology (Hematology (Amsterdam, Netherlands))
[2021, 26(1):328-339]

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Contribution of oxidative stress in the mechanisms of postoperative complications and multiple organ dysfunction syndrome.

Javier Toro-Pérez, Ramón Rodrigo,

<h4>Background</h4>The extent of the damage following surgery has been subject of study for several years. Numerous surgical complications can impact postoperative quality of life of patients and even can cause mortality. Although these complications are generally due to multifactorial mechanisms, oxidative stress plays a key pathophysiological role. Moreover, oxidative stress ... Read more >>

Redox Rep (Redox report : communications in free radical research)
[2021, 26(1):35-44]

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Outcomes and risk management in type B aortic dissection patients with acute kidney injury: a concise review.

Xiaolan Chen, Ming Bai, Shiren Sun, Xiangmei Chen,

<h4>Purpose</h4>Type B aortic dissection is a rare but life-threatening disease. Thoracic endovascular aortic repair (TEVAR) was widely used for Type B aortic dissection patients in the last decade due to the lower mortality and morbidity compared with open chest surgical repair (OCSR). AKI in type B aortic dissection is a ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):585-596]

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An experimental exposure study revealing composite airway effects of physical exercise in a subzero environment.

Linda Eklund, Filip Schagatay, Ellen Tufvesson, Rita Sjöström, Lars Söderström, Helen G Hanstock, Thomas Sandström, Nikolai Stenfors,

Exposure to a cold climate is associated with an increased morbidity and mortality, but the specific mechanisms are largely unknown. People with cardiopulmonary disease and winter endurance athletes are particularly vulnerable. This study aimed to map multiple domains of airway responses to exercise in subzero temperature in healthy individuals.Thirty-one healthy ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1897213]

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Isolation, identification, and phylogenetic analysis of subgroup III strain of bovine respiratory syncytial virus contributed to outbreak of acute respiratory disease among cattle in Northeast China.

Shuo Jia, Xin Yao, Yaqi Yang, Chao Niu, Yi Zhao, Xiaomei Zhang, Ronghui Pan, Xiaoxia Jiang, Sun Xiaobo, Xinyuan Qiao, Xueting Guan, Yigang Xu,

Bovine respiratory syncytial virus (BRSV) is a clinically important causative agent of acute respiratory diseases in postweaning calves and feedlot cattle and causes numerous economic losses to the cattle industry. In June 2018, an outbreak of an acute respiratory disease occurred among 4- to 10-month-old calves on three intensive beef ... Read more >>

Virulence (Virulence)
[2021, 12(1):404-414]

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Research priorities to support evidence-informed policies and advocacy for access to safe abortion care in sub-Saharan Africa.

Anthony Idowu Ajayi, Ramatou Ouedraogo, Kenneth Juma, Grace Kibunja, Collins Cheruiyot, Meggie Mwoka, Emmy Kageha Igonya, Winnie Opondo, Emmanuel Otukpa, Caroline W Kabiru, Boniface Ayanbekongshie Ushie,

A key obstacle to advocacy efforts to promote legal and policy reforms that ensure women's and girls' access to comprehensive abortion care (CAC) is the lack of relevant and timely evidence. This commentary outlines a research agenda-setting initiative that identified research priorities to support evidence-informed policy and advocacy for CAC ... Read more >>

Sex Reprod Health Matters (Sexual and reproductive health matters)
[2021, 29(1):1881207]

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Pathogenic assessment of avian influenza viruses in migratory birds.

Eun-Ha Kim, Young-Ll Kim, Se Mi Kim, Kwang-Min Yu, Mark Anthony B Casel, Seung-Gyu Jang, Philippe Noriel Q Pascua, Richard J Webby, Young Ki Choi,

<b>ABSTRACT</b>Several subtypes of avian influenza (AI) viruses have caused human infections in recent years; however, there is a severe knowledge gap regarding the capacity of wild bird viruses to infect mammals. To assess the risk of mammalian infection by AI viruses from their natural reservoirs, a panel of isolates from ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):565-577]

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Human challenge trials to assess the efficacy of currently approved COVID-19 vaccines against SARS-CoV-2 variants.

Shan Su, Yiming Shao, Shibo Jiang,

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):439-441]

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Pathogenesis and shedding of Usutu virus in juvenile chickens.

Sarah C Kuchinsky, Francesca Frere, Nora Heitzman-Breen, Jacob Golden, Ana Vázquez, Christa F Honaker, Paul B Siegel, Stanca M Ciupe, Tanya LeRoith, Nisha K Duggal,

Usutu virus (USUV; family: <i>Flaviviridae,</i> genus: <i>Flavivirus</i>), is an emerging zoonotic arbovirus that causes severe neuroinvasive disease in humans and has been implicated in the loss of breeding bird populations in Europe. USUV is maintained in an enzootic cycle between ornithophilic mosquitos and wild birds. As a member of the ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):725-738]

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Assessment of Lebanese healthcare professionals' awareness on acquired haemophilia: a cross-sectional study.

Ali Taher, Layal Al Mahmasani, Abdallah Aadra, Patricia Yazbeck, Georges Abi Saad, Fadi Nasr, Rita Habib, Amal Chalfoun, Fadi Haddad,

<h4>Background</h4>Acquired haemophilia A (AHA) is a rare immune-mediated disorder characterised by the development of autoantibodies against factor VIII. Morbidity and mortality are in general high due to multiple factors including the age of the patient, underlying diseases, toxic effects of available treatments and bleeding itself.<h4>Objective</h4>To assess the awareness about AHA ... Read more >>

Hematology (Hematology (Amsterdam, Netherlands))
[2021, 26(1):83-87]

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Teriflunomide provides protective properties after oxygen-glucose-deprivation in hippocampal and cerebellar slice cultures.

Anna Wolters, Judith Reuther, Philipp Gude, Thomas Weber, Carsten Theiss, Heike Vogelsang, Veronika Matschke,

One of the major challenges in emergency medicine is out-of-hospital cardiac arrest (OHCA). Every year, about 53-62/100 000 people worldwide suffer an out-of-hospital cardiac arrest with serious consequences, whereas persistent brain injury is a major cause of morbidity and mortality of those surviving a cardiac arrest. Today, only few and ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(11):2243-2249]

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Risk factors and outcomes of cardiovascular disease readmission within the first year after dialysis in peritoneal dialysis patients.

Jianbo Li, Naya Huang, Zhong Zhong, Pema Joe, Dan Wang, Zhen Ai, Lisha Wu, Lanping Jiang, Fengxian Huang,

<h4>Background</h4>In the first year of dialysis, patients are vulnerable to cardiovascular disease (CVD) hospitalization, but knowledge regarding the risk factors and long-term outcomes of cardiovascular readmission within the first year after dialysis in incident continuous ambulatory peritoneal dialysis (CAPD) patients is limited.<h4>Methods</h4>This retrospective cohort study was conducted in incident CAPD ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):159-167]

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Any heart failure treatments associated with worsening renal function in patients admitted due to acute heart failure?

Chutatip Limkunakul, Benjawan Srisantithum, Yotin Lerdrattanasakulchai, Thanakorn Laksomya, Jatuphorn Jungpanich, Kittisak Sawanyawisuth,

<h4>Background</h4>Worsening renal function (WRF) occurs in approximately 25% of acute heart failure patients, and both baseline characteristics and heart failure treatment may increase the risk of WRF. This study aimed to evaluate additional risk factors for WRF in acute heart failure, particularly those related to heart failure treatment.<h4>Methods</h4>This was a ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):123-127]

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Psychological problems in general population during covid-19 pandemic in Pakistan: role of cognitive emotion regulation.

Maryam Riaz, Mueen Abid, Zaqia Bano,

<b>Objectives:</b> To explore psychological problems (Anxiety, Depression and Stress) in general population during Covid-19 pandemic. To find predictive effects of cognitive emotion regulation on psychological problems. <b>Methodology:</b> Convenient sampling technique was used to obtain the sample of 500 participants (Male = 239, Female = 261). Research instrument consists of four ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):189-196]

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Phylogenetic Group B2 Expressed Significant Biofilm Formation among Drug Resistant Uropathogenic Escherichia coli.

Saima Javed, Zulfiqar Ali Mirani, Zaid Ahmed Pirzada,

Biofilm is an important virulent marker attributed to the development of urinary tract infections (UTIs) by uropathogenic <i>E. coli</i> (UPEC). Drug-resistant and biofilm-producing UPEC are highly problematic causing catheter-associated or recurrent UTIs with significant morbidity and mortality. The aim of the current study was to investigate the prevalence of biofilm ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2021, 16(1):1845444]

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The effect of hyperkalemia and long inter-dialytic interval on morbidity and mortality in patients receiving hemodialysis: a systematic review.

Danai Bem, Daniel Sugrue, Ben Wilding, Ina Zile, Karin Butler, David Booth, Eskinder Tafesse, Phil McEwan,

<h4>Background</h4>Patients with chronic kidney disease, especially those receiving hemodialysis (HD), are at risk of hyperkalemia (HK). This systematic review aimed to evaluate the prevalence of HK in patients with renal disease receiving HD and collate evidence on the effect of HK and differing HD patterns (i.e., long vs. short inter-dialytic ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):241-254]

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Questions and answers on iron deficiency treatment selection and the use of intravenous iron in routine clinical practice.

Toby Richards, Christian Breymann, Matthew J Brookes, Stefan Lindgren, Iain C Macdougall, Lawrence P McMahon, Malcolm G Munro, Elizabeta Nemeth, Giuseppe M C Rosano, Ingolf Schiefke, Günter Weiss,

Iron deficiency is a common cause of morbidity and can arise as a consequence or complication from many diseases. The use of intravenous iron has increased significantly in the last decade, but concerns remain about indications and administration. Modern intravenous iron preparations can facilitate rapid iron repletion in one or ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):274-285]

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A host-based whole genome sequencing study reveals novel risk loci associated with severity of influenza A(H1N1)pdm09 infection.

Mo Li, Yongkun Chen, Tao Chen, Shixiong Hu, Luan Chen, Lu Shen, Fangcai Li, Jing Yang, Yan Sun, Dayan Wang, Lin He, Shengying Qin, Yuelong Shu,

Influenza A(H1N1)pdm09 virus has remained in a seasonal circulation since being recognized in 2009. Although it followed a mild course in most patients, in others it caused a series of severe clinical illnesses. Epidemiologic studies have implicated that host factors have a major influence on the disease severity of influenza ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):123-131]

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Naoxintong accelerates diabetic wound healing by attenuating inflammatory response.

Leyu Fang, Lu Chen, Min Song, Juan He, Lusha Zhang, Chunxiao Li, Qianyi Wang, Wenjie Yang, Wei Sun, Yuze Leng, Hong Shi, Shaoxia Wang, Xiumei Gao, Hong Wang,

<h4>Context</h4>Naoxintong (NXT), a prescribed traditional Chinese medicine, widely used in cerebrovascular and cardiovascular diseases, could be effective in diabetic wounds.<h4>Objective</h4>This study evaluates the wound healing activity of NXT by employing an excisional wound splinting model.<h4>Materials and methods</h4>NXT was dissolved in saline and given daily by gavage. Wounds were induced at ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):252-261]

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Diagnostic value of TWEAK for predicting active lupus nephritis in patients with systemic lupus erythematosus: a systematic review and meta-analysis.

Hao-Yang Ma, Shuang Chen, Wei-Dong Cao, Cui-Ting Min,

<h4>Purpose</h4>Accumulative studies showed that tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) was up-regulated in the blood and urine from patients diagnosed with lupus nephritis (LN) and that it might be used as a novel biomarker for active LN. This meta-analysis aimed to determine the diagnostic value of TWEAK ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):20-31]

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Self-managed abortion: a constellation of actors, a cacophony of laws?

Lucía Berro Pizzarossa, Rishita Nandagiri,

Sex Reprod Health Matters (Sexual and reproductive health matters)
[2021, 29(1):1899764]

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Post COVID 19 multisystem inflammatory syndrome in an older adult.

Alexander Parpas, Michael Yudd, Albert W Dreisbach, Jennine Michaud,

Ren Fail (Renal failure)
[2021, 43(1):530-532]

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Oxidative stress in genetically triggered thoracic aortic aneurysm: role in pathogenesis and therapeutic opportunities.

Stefanie S Portelli, Brett D Hambly, Richmond W Jeremy, Elizabeth N Robertson,

<b>Background:</b> The primary objective of this review was to explore the contribution of oxidative stress to the pathogenesis of genetically-triggered thoracic aortic aneurysm (TAA). Genetically-triggered TAAs manifest substantial variability in onset, progression, and risk of aortic dissection, posing a significant clinical management challenge. There is a need for non-invasive biomarkers ... Read more >>

Redox Rep (Redox report : communications in free radical research)
[2021, 26(1):45-52]

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Indigenous women's reproductive health in the Arctic zone of Western Siberia: challenges and solutions.

Elena Bogdanova, Sergei Andronov, Andrey Lobanov, Ruslan Kochkin, Andrei Popov, Ildiko Asztalos Morell, JonØyvind Odland,

In the Russian Arctic, alarming trends (shortage of nomadic Indigenous women, high reproductive loss, child mortality rates) indicate long-term changes towards demographic decline. This study aimed at comparing some indicators of the reproductive health (childbirth rates, number of pregnancies, pregnancy loss) of Indigenous and non-Indigenous women in the exploration of ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1855913]

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