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Miliary Tuberculosis

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Fatal congenital tuberculosis owing to late diagnosis of maternal tuberculosis: case report and review of congenital tuberculosis in China.

Jing-Min Sun, Chang Wang, Dan-Qun Jin, Fang Deng,

Congenital tuberculosis (TB) is rare and the prognosis is poor if not detected early. The diagnosis is often delayed owing to non-specific clinical presentation, misdiagnosis and undiagnosed maternal TB during pregnancy. A 12-day-old girl presented with a 5-day history of fever, cough, poor feeding and respiratory distress. Her mother had ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-5]

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Miliary cerebrospinal lesions caused by Nocardia beijingensis in an immunocompetent patient.

Hajime Tanaka, Katsunari Kiko, Yudai Watanabe, Takashi Yaguchi, Shigeru Oya, Toshiaki Shiojiri,

The genus Nocardia usually infect immunocompromised patients. Pulmonary nocardiosis is the most common Nocardia-induced infection while central nervous system (CNS) is the most common extrapulmonary site to develop nocardial disease. Approximately 54 % cases of previously reported nocardial brain abscesses were solitary lesions, while 38 % cases had multiple lesions; ... Read more >>

IDCases (IDCases)
[2020, 20:e00737]

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A Rare Case of Primary Myelofibrosis With a Solitary 1q Triplication.

Jin Hong Kim, Duck An Kim, Young Eun Kim,

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(2):174-176]

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A case of miliary tuberculosis presenting as massive hepatosplenomegaly and fatal hepatic failure.

Junichiro Kawagoe, Yuki Maeda, Goro Kawamata, Nobuyuki Koyama, Hiroyuki Nakamura, Kazutetsu Aoshiba,

IDCases (IDCases)
[2020, 19:e00707]

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[Tuberculosis and immune reconstitution inflammatory syndrome. Pediatric case].

Ana C Bustos, Gabriela M Zárate,

Tuberculosis is a very frequent disease in our environment. Although early detection and adequate treatment achieve cure in most patients, the difficulty in diagnosis, the abandonment of treatment and the appearance of resistance to traditional drugs generate that at present it continues to represent an important public health problem. In ... Read more >>

Arch Argent Pediatr (Archivos argentinos de pediatria)
[2020, 118(1):e39-e42]

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Central nervous system tuberculoma with miliary tuberculosis in the elderly.

Syuichi Tetsuka, Tomohiro Suzuki, Tomoko Ogawa, Ritsuo Hashimoto, Hiroyuki Kato,

The aging phenomenon of tuberculosis (TB) patients is recognized all over the world, but no country is as prominent as Japan. Central nervous system (CNS) TB includes clinical entities: tuberculous meningitis, intracranial tuberculoma, and clinical features of CNS TB in the elderly may be atypical, non-specific, and confused with concomitant ... Read more >>

IDCases (IDCases)
[2020, 19:e00710]

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Abdominal Tuberculosis Mimicking Cancer Clinically and on Fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET) Imaging: A Two-Case Series.

Chiara Di Renzo, Parissa Tabrizian, David E Kozuch, Maria Isabel Fiel, Myron E Schwartz,

BACKGROUND Miliary tuberculosis (MT) is the disseminated form of tuberculosis (TB) and it is a potentially fatal condition. Diagnosis is often delayed because symptoms are typically nonspecific or absent, and misdiagnosis in favor of other diseases is common. We report 2 cases of disseminated TB that were diagnosed during or ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e918901]

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Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis.

Madeleine G Moule, Jeffrey D Cirillo,

Mycobacterium tuberculosis is primarily a respiratory pathogen. However, 15% of infections worldwide occur at extrapulmonary sites causing additional complications for diagnosis and treatment of the disease. In addition, dissemination of M. tuberculosis out of the lungs is thought to be more than just a rare event leading to extrapulmonary tuberculosis, ... Read more >>

Front Cell Infect Microbiol (Frontiers in Cellular and Infection Microbiology)
[2020, 10:65]

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Tubercular granuloma mimicking pyogenic liver abscess.

Mohit Garg, Yasmeen Khan, Monika Pathania,

Hepatic Tuberculosis (TB) is extremely rare without miliary involvement in immunocompetent patients. Even in countries like India where TB is a major public health problem only few cases have been diagnosed and treated. We report a case of an immunocompetent patient who presented with undiagnosed pyrexia of 11 days, was ... Read more >>

J Family Med Prim Care (Journal of family medicine and primary care)
[2020, 9(1):424-427]

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Ground-glass opacity as a paradoxical reaction in miliary tuberculosis: A case report and review of the literature.

Yuki Tokuyama, Takeshi Matsumoto, Yusuke Kusakabe, Naoki Yamamoto, Kensaku Aihara, Shinpachi Yamaoka, Michiaki Mishima,

A paradoxical reaction (PR) is an excessive immune response occurring during antitubercular therapy (ATT), but is rare in patients with miliary tuberculosis. A 78-year-old woman complained of general malaise, loss of appetite, and fever for 10 days. Chest computed tomography (CT) showed diffuse, bilateral, discrete miliary nodules. The patient was ... Read more >>

IDCases (IDCases)
[2020, 19:e00685]

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A rare case of lung adenocarcinoma: Unusual presentation with miliary mottling.

Pankaj Goyal, Sneha J Bothra, Parveen Jain, Udip Maheshwari, Chaturbhuj Agarwal, Dinesh Chandra Doval,

Lung India (Lung India : official organ of Indian Chest Society)
[2020, 37(1):69-71]

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Hemophagocytic Lymphohistiocytosis Induced Cytokine Storm Secondary to Human Immunodeficiency Virus Associated Miliary Tuberculosis.

Meghana Parsi, Kinjal Dargan,

Hemophagocytic lymphohistiocytosis (HLH) is a rarely diagnosed fatal inflammatory disease associated with an overactive immune system. It occurs in a host of conditions, with human immunodeficiency virus (HIV) being a rare but serious cause, usually occurring in patients with acquired immunodeficiency syndrome (AIDS). The diagnosis of HLH can be very ... Read more >>

Cureus (Cureus)
[2020, 12(1):e6589]

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Role of Fiberoptic Bronchoscopy in the Rapid Diagnosis of Sputum Smear-negative Disseminated Tuberculosis with Pulmonary Miliary Infiltrates.

Fahmi Yousef Khan, Aisha Hussein Aladab,

Objectives:We sought to evaluate the role of bronchoscopy-related procedures such as bronchoalveolar lavage (BAL), bronchial wash (BW), bronchial brush (B brush), transbronchial biopsy (TBB), and post-bronchoscopy sputum (PBS), alone or in combination, in the rapid diagnosis of negative sputum smear disseminated tuberculosis (TB). Methods:We performed a secondary post hoc analysis ... Read more >>

Oman Med J (Oman medical journal)
[2020, 35(1):e87]

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Brain miliary enhancement.

Joseph C J Bot, Linda Mazzai, Rogier E Hagenbeek, Silvia Ingala, Bob van Oosten, Esther Sanchez-Aliaga, Frederik Barkhof,

PURPOSE:Miliary enhancement refers to the presence of multiple small, monomorphic, enhancing foci on T1-weighted post-contrast MRI images. In the absence of a clear clinical presentation, a broad differential diagnosis may result in invasive procedures and possibly brain biopsy for diagnostic purposes. METHODS:An extensive review of the literature is provided for ... Read more >>

Neuroradiology (Neuroradiology)
[2020, 62(3):283-300]

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Multiple Cranial Tuberculomas Without Meningitis in Two Infants With Miliary Tuberculosis.

Grace St Cyr, Jeffrey R Starke,

Magnetic resonance imaging may detect central nervous system involvement even when cerebrospinal fluid is normal and tests to detect Mycobacterium tuberculosis are negative. We describe 2 cases of miliary tuberculosis in young children with clinically unexpected central nervous system involvement. Magnetic resonance imaging of the brain should be considered part ... Read more >>

Pediatr. Infect. Dis. J. (The Pediatric infectious disease journal)
[2019, 38(12):e337-e339]

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Miliary tuberculosis and choroidal tuberculoma in a three-month old baby girl: Diagnosis and follow-up of a case.

S Macías-Franco, M Fernández-García, C Costales-Álvarez, J Mayordomo-Colunga, P Rozas-Reyes,

A three-month old baby girl presented with fever of unknown origin and with signs of worsening of this episode. Funduscopy showed a solitary choroidal lesion in her left eye, as well as extraocular lesions suggesting disseminated tuberculosis. A favourable outcome was achieved after quadruple antibiotic course and cortisone therapy. Disseminated ... Read more >>

Arch Soc Esp Oftalmol (Archivos de la Sociedad Espanola de Oftalmologia)
[2020, 95(1):42-44]

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Primary Tuberculous Mastitis: The first report from Syria.

Sadallah Kayali, Aos Alhamid, Ayman Kayali, Aghyad Kudra Danial, Muhamad Zakaria Brimo Alsaman, Ahmad Alhamid, Kusay Ayoub,

INTRODUCTION:Primary breast tuberculosis is a rare form of extrapulmonary tuberculosis even in endemic regions. To our knowledge, this is the first report of Primary breast tuberculosis from Syria. CASE PRESENTATION:We report a case of a 37-year-old female who admitted to the surgical clinic with a 4-month history of gradually growing ... Read more >>

Int J Surg Case Rep (International journal of surgery case reports)
[2020, 68:48-51]

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Mycobacterium tuberculosis infection in psoriatic patients treated with biologics: Real-world data from 18 Japanese facilities.

Sakae Kaneko, Noriko Tsuruta, Kazuki Yamaguchi, Takuya Miyagi, Kenzo Takahashi, Yuko Higashi, Shin Morizane, Hayato Nomura, Michiya Yamaguchi, Ryosuke Hino, Yu Sawada, Motonobu Nakamura, Bungo Ohyama, Chika Ohata, Kentaro Yonekura, Hiroaki Hayashi, Tetsuji Yanase, Yuki Matsuzaka, Kazunari Sugita, Satoko Kikuchi, Chikage Mitoma, Takeshi Nakahara, Masutaka Furue, Fusako Okazaki, Yuta Koike, Shinichi Imafuku, ,

Although rare, tuberculosis has been reported with biologic treatment against psoriasis in Japan, a tuberculosis medium-burden country. Mycobacterial infection often develops after a long incubation period and might not have been adequately identified in clinical trials or post-marketing surveillance. To determine the real-world incidence of tuberculosis in psoriatic patients treated ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, 47(2):128-132]

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Reactivation of latent tuberculosis infection induced by cabazitaxel in a patient with prostate cancer: A case report.

Mamoru Hashimoto, Takafumi Minami, Mamoru Hamaguchi, Saizo Fujimoto, Tomoki Takahashi, Takashi Kikuchi, Shogo Adomi, Eri Banno, Takayuki Ohzeki, Nobutaka Shimizu, Yasunori Mori, Masahiro Nozawa, Kazuhiro Nose, Kazuhiro Yoshimura, Hirotsugu Uemura,

RATIONALE:Latent tuberculosis infection (LTBI) describes the dormant state of tuberculosis (TB), in which persistent immune-related interaction between TB and T-cells maintain its state. Cabazitaxel (CBZ) is reported to improve overall survival in patients with castration-resistant prostate cancer (CRPC) after progression observed in regimens including docetaxel. CBZ is known for severe ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(51):e18436]

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Pulmonary alveolar microlithiasis and interstitial pneumonitis: a case report of the west of Iran.

Mazaher Ramezani, Zahra Aminparast, Masoud Sadeghi,

Pulmonary alveolar microlithiasis (PAM) is a rare disease with autosomal recessive inheritance. Herein, a 20-year-old lady referred to the hospital with a dry cough for two years. The chest X-ray findings were bilateral reticulonodular opacities in both lungs and honeycomb appearance suspicious for miliary tuberculosis and idiopathic pulmonary fibrosis. A ... Read more >>

Biomedicine (Taipei) (BioMedicine)
[2019, 9(4):28]

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1362. A Case Series of Miliary Tuberculosis in North West London.

Hannah Gorgui-Naguib, Che Cootauco, Gurjinder Sandhu, Padmasayee Papineni,

AbstractBackgroundMiliary tuberculosis (mTB) is a severe presentation of TB with high mortality. We reviewed data from a cohort of patients with mTB in an area of London serving an ethnically diverse population with the highest TB endemicity in the UK.MethodsRetrospective analysis of laboratory and medical records, radiology and microbiology results ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S493-S493]

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Tuberculosis among patients treated with TNF inhibitors for rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis in Slovenia: a cohort study.

Ziga Rotar, Petra Svetina, Matija Tomsic, Alojzija Hočevar, Sonja Prapotnik,

OBJECTIVES:This study aimed to assess the risk of tuberculosis (TB) in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) treated with any of the commercially available tumour necrosis factor inhibitors (TNFis) in Slovenia. DESIGN:This is a cohort, registry (biorx.si) cross-linked with the Slovenian National TB Registry. ... Read more >>

BMJ Open (BMJ open)
[2020, 10(2):e034356]

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Repeated Chest Computed Tomography Revealed Early-stage Miliary Tuberculosis.

Hideo Okuno, Hideharu Hagiya, Shigeto Hamaguchi, Kazunori Tomono,

Intern. Med. (Internal medicine (Tokyo, Japan))
[2020, 59(3):461-462]

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Cryptogenic Organizing Pneumonia with a Rare Radiographic Presentation of a Diffuse Micronodular Pattern Mimicking Miliary Lung Infiltration: A Case Report and Review of the Literature.

Jakrin Kewcharoen, Kittika Poonsombudlert, Sakda Sathirareuangchai, Wichit Sae-Ow, Hanh La, Narin Sriratanaviriyakul,

We reported a case of cryptogenic organizing pneumonia (COP) presenting with an unusual diffuse micronodular pattern (DMP) mimicking miliary lung infiltration. The patient is a 66-year-old man with a past medical history of diabetes mellitus type 2 and hyperlipidemia who presented with progressive dyspnea associated with significant weight loss and ... Read more >>

Case Rep Pulmonol (Case reports in pulmonology)
[2020, 2020:2094625]

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Tuberculosis disease in children and adolescents on therapy with anti-tumor necrosis factor-alpha agents: a collaborative, multi-centre ptbnet study.

Antoni Noguera-Julian, Joan Calzada-HernÁndez, Folke Brinkmann, Robindra Basu Roy, Olga Bilogortseva, Michael Buettcher, Isabel Carvalho, Vira Chechenyeva, Lola Falcon, Florian Goetzinger, Carmelo Guerrero-Laleona, Peter Hoffmann, Marija Jelusic, Tim Niehues, Iveta Ozere, Fiona Shackley, Elena Suciliene, Steven B Welch, Elisabeth H SchÖLvinck, Nicole Ritz, Marc Tebruegge,

BACKGROUND:In adults, anti-tumor-necrosis-factor (TNF)-α therapy is associated with progression of latent tuberculosis infection (LTBI) to tuberculosis (TB) disease. The existing paediatric data are very limited. METHODS:Retrospective multi-centre study within the Paediatric Tuberculosis Network European Trials Group, capturing patients <18 years who developed TB disease during anti-TNF-α therapy. RESULTS:Sixty-six tertiary healthcare ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2019, :]

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