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Migraine in Children

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The Humanistic and Economic Burden of Pediatric Focal Seizures in the United States.

Sarah N Gibbs, Jiyoon Choi, Ibrahim Khilfeh, K Hamzah Ahmed, Irina Yermilov, Eric Segal,

OBJECTIVE:To better understand the humanistic and economic burden of focal seizures in children 2-12 years old. METHODS:We conducted a targeted literature review by searching MEDLINE for English-language publications reporting on children 2-12 years old with focal seizures published in the United States since 2008. RESULTS:Thirty-five publications were included. Incidence of ... Read more >>

J. Child Neurol. (Journal of child neurology)
[2020, :883073820911785]

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The Effects of the Rome IV Criteria on Pediatric Gastrointestinal Practice.

Desiree F Baaleman, Carlo Di Lorenzo, Marc A Benninga, Miguel Saps,

PURPOSE OF REVIEW:To evaluate the impact of the implementation of the Rome IV criteria on pediatric gastrointestinal practice. RECENT FINDINGS:In 2016, the Rome IV criteria were published, providing an update of symptom-based criteria to diagnose children with functional gastrointestinal disorders (FGIDs). For neonates and toddlers, Wessel's criteria for diagnosing infant ... Read more >>

Curr Gastroenterol Rep (Current gastroenterology reports)
[2020, 22(5):21]

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Irritability and its relationships with psychological symptoms in adolescents with migraine: a case-control study.

Halit Necmi Uçar, Uğur Tekin, Emine Tekin,

OBJECTIVE:The aim of this study was to investigate self- and parent-reported irritability in adolescents with migraine and to evaluate the relationship between self- and parent-reported irritability and psychological symptoms in adolescents with migraine. METHODS:The sample of this single-center cross-sectional case-control study consisted of 71 adolescents with migraine (who were followed ... Read more >>

Neurol. Sci. (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2020, :]

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The Efficacy and Safety of Topiramate in the Prevention of Pediatric Migraine: An Update Meta-Analysis.

Xinwei Wu, Yan Zhang, Mei Lu, Xiaolin Yu, Xiang Ye, Xingbang Wang, Peiyan Shan,

Background: Migraine is the most common acute primary headache in children and adolescents. In 2014, topiramate became the first preventive drug for migraine, approved by the Food and Drug Administration (FDA) for adolescents. This meta-analysis was aimed to evaluate the efficacy and safety of topiramate in the prevention of pediatric ... Read more >>

Front Pediatr (Frontiers in Pediatrics)
[2020, 8:28]

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Concern of Photosensitive Seizures Evoked by 3D Video Displays or Virtual Reality Headsets in Children: Current Perspective.

Lawrence Tychsen, Liu Lin Thio,

This review assesses the risk of a photic-induced seizure in a child during viewing of 3D (binocular 3 dimensional, stereoscopic) movies or games, either on standard video displays or when wearing a virtual reality (VR) headset. Studies published by pediatric epilepsy experts emphasize the low risk of 3D viewing even ... Read more >>

Eye Brain (Eye and brain)
[2020, 12:45-48]

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Evaluation of Gastrointestinal Functions in Children with Familial Mediterranean Fever Disease

Ali İhsan Anadolulu, Çiğdem Ulukaya Durakbaşa, müferret ergüven, ıtır ebru zemheri, gonca gerçel,

<title>Abstract</title> <p> Background The aim of this study was to evaluate the effect of amyloid deposition in colon mucosa on the results of anorectal manometry test and the use of ROME III questionnaire in patients with Familial Mediterranean Fever (FMF). Methods The files of patients diagnosed with FMF ... Read more >>

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Migraine and Sleep in Children: A Bidirectional Relationship.

Ivan M Pavkovic, Sanjeev V Kothare,

Migraine and sleep disorders in children exhibit a bidirectional relationship. This relationship is based on shared pathophysiology. Migraine involves activation of the trigeminal vascular system. Nociceptive neurons that innervate the dura release various vasoactive peptides. Calcitonin gene-related peptide is the most active of these peptides. Neural pathways that are involved ... Read more >>

Pediatr. Neurol. (Pediatric neurology)
[2020, :]

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Alleviation of migraine symptoms by application of repetitive peripheral magnetic stimulation to myofascial trigger points of neck and shoulder muscles - A randomized trial.

Tabea Renner, Nico Sollmann, Florian Heinen, Lucia Albers, Florian Trepte-Freisleder, Birgit Klose, Helene König, Sandro M Krieg, Michaela V Bonfert, Mirjam N Landgraf,

Migraine is a burdensome disease with an especially high prevalence in women between the age of 15 and 49 years. Non-pharmacological, non-invasive therapeutic methods to control symptoms are increasingly in demand to complement a multimodal intervention approach in migraine. Thirty-seven subjects (age: 25.0 ± 4.1 years; 36 females) diagnosed with high-frequency episodic ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):5954]

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Evaluation of retinal microvasculature and foveal avascular zone by the optical coherence tomography angiography in pediatric migraine patients.

Gamze Dereli Can, Mehmet Erol Can, Arzu Ekici,

To compare the foveal avascular zone (FAZ), macular and peripapillary vessel density and retinal nerve fiber layer (RNFL) thickness between pediatric migraine patients and healthy subjects. A total of 108 eyes of 54 children with migraine without aura and 94 eyes of 47 age- and gender-matched healthy subjects were included. ... Read more >>

Acta Neurol Belg (Acta neurologica Belgica)
[2020, :]

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Associations between migraine occurrence and the effect of aura, age at onset, family history, and sex: A cross-sectional study.

Yu-Wei Hsu, Chih-Sung Liang, Jiunn-Tay Lee, Hsuan-Te Chu, Meei-Shyuan Lee, Chia-Lin Tsai, Guan-Yu Lin, Yu-Kai Lin, Tsung-Han Ho, Fu-Chi Yang,

INTRODUCTION:The relationships between family history, sex, age at onset, and migraine occurrence have been documented. However, the associations between these factors across different sexes and subgroups of patients have yet to be elucidated. This study evaluated the association between family history and migraine in male and female patients experiencing episodic ... Read more >>

PLoS ONE (PloS one)
[2020, 15(2):e0228284]

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Familial hemiplegic migraine with a PRRT2 mutation: Phenotypic variations and carbamazepine efficacy.

Sato Suzuki-Muromoto, Rika Kosaki, Kenjiro Kosaki, Masaya Kubota,

OBJECTIVE:To understand the clinical characteristics of familial hemiplegic migraine (FHM) caused by a PRRT2 mutation and to examine the efficacy of preventive treatment. METHODS:Using the literature, we investigated clinical details of FHM in 3 generations of patients with a PRRT2 mutation and compared them with those in 17 patients with ... Read more >>

Brain Dev. (Brain & development)
[2020, 42(3):293-297]

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Does a Minority of Children With Functional Gastrointestinal Disorders Receive Formal Diet Advice?

Ligia Alfaro Cruz, Charles Minard, Danielle Guffey, Bruno P Chumpitazi, Robert J Shulman,

BACKGROUND:Diet therapies may be recommended for pediatric functional gastrointestinal disorders (FGIDs). However, little is known about the frequency with which diet therapy is recommended in FGIDs. Our aims were to determine and contrast the frequency and types of diet recommendations provided to children with FGIDs by pediatric gastroenterologists (PGIs) versus ... Read more >>

JPEN J Parenter Enteral Nutr (JPEN. Journal of parenteral and enteral nutrition)
[2020, :]

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Sensory Processing Patterns affect Headache Severity among Adolescents with Migraine

Jacob Genizi, Ayelet Halevy, Mitchell Schertz, Khaled Osman, Nurit Assaf, Idan Segal, Isaac Sr, Aharon Kessel, Batya Engel-Yeger,

<title>Abstract</title> <p> Objective : To evaluate the relationship between pain catastrophizing level, sensory processing patterns, and headache severity among adolescents with episodic migraine. Background : Catastrophizing about pain is a critical variable in how we understand adjustment to pain and has a unique contribution in predicting pain intensity. ... Read more >>

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The Profile and Prognosis of Youth With Status Migrainosus: Results From an Observational Study.

Serena L Orr, Abigail Turner, Marielle A Kabbouche, Paul S Horn, Hope L O'Brien, Joanne Kacperski, Susan LeCates, Shannon White, Jessica Weberding, Mimi N Miller, Scott W Powers, Andrew D Hershey,

OBJECTIVE:To characterize the clinical features of a large sample of children, adolescents, and young adults with a history of status migrainosus (SM) and to describe their short-term prognosis. BACKGROUND:Data on the clinical characteristics of children and adolescents with SM are sparse and little is known about the prognosis of this ... Read more >>

Headache (Headache)
[2020, :]

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Pattern of Comorbid Headache Among Children with Epilepsy Treated for Neurocysticercosis.

Hitesh Bhatia, Radhamohan Rana, Riya Goyal, Virender Kumar Gehlawat, Jaya Shankar Kaushik,

The present cross-sectional study was designed to describe the pattern of comorbid headache among children with epilepsy (CWE) secondary to neurocysticercosis (NCC). Children aged 6 to 14 y (n = 70) already diagnosed with neurocysticercosis on a minimum follow-up of six months were consecutively enroled in the study over a period of four ... Read more >>

Indian J Pediatr (Indian journal of pediatrics)
[2020, :]

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An Important Pediatric Stroke Mimic: Hemiplegic Migraine.

Michael T Jurkiewicz, Arastoo Vossough, Avrum N Pollock,

Stroke is relatively rare in children but has become increasingly recognized clinically. Hemiplegic migraine (HM) is a rare subtype of migraine, with attacks typically beginning in childhood or adolescence. Attacks are characterized by migraine headaches and motor weakness, which develop over several minutes. HM may therefore mimic acute stroke; however, ... Read more >>

Can J Neurol Sci (The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques)
[2020, 47(2):235-236]

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The relationship between abdominal pain and emotional wellbeing in children and adolescents in the Raine Study.

Oyekoya T Ayonrinde, Oyedeji A Ayonrinde, Leon A Adams, Frank M Sanfilippo, Therese A O' Sullivan, Monique Robinson, Wendy H Oddy, John K Olynyk,

Abdominal pain is a common reason for medical visits. We examined the prevalence, gastrointestinal, and emotional significance of abdominal pain in a population-based cohort serially followed up from birth to 17 years. Children and adolescents from Generation 2 of the Raine Study participated in comprehensive cross-sectional assessments at ages 2, ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):1646]

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Editorial: Clinical and Pathophysiological Peculiarities of Headache in Children and Adolescents.

Massimiliano Valeriani, Ishaq Abu-Arafeh, Aynur Özge,

Front Neurol (Frontiers in neurology)
[2019, 10:1280]

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Efficacy, Safety, and Acceptability of Pharmacologic Treatments for Pediatric Migraine Prophylaxis: A Systematic Review and Network Meta-analysis.

Cosima Locher, Joe Kossowsky, Helen Koechlin, Thanh Lan Lam, Johannes Barthel, Charles B Berde, Jens Gaab, Guido Schwarzer, Klaus Linde, Karin Meissner,

Importance:Migraine is one of the most common neurologic disorders in children and adolescents. However, a quantitative comparison of multiple preventive pharmacologic treatments in the pediatric population is lacking. Objective:To examine whether prophylactic pharmacologic treatments are more effective than placebo and whether there are differences between drugs regarding efficacy, safety, and ... Read more >>

JAMA Pediatr (JAMA pediatrics)
[2020, :]

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Metabolic treatments of migraine.

Marco Lisicki, Jean Schoenen,

Introduction: Most preventive migraine treatments modify the brain's excitation/inhibition balance and/or serotonin metabolism, which likely accounts for their unfavorable adverse effect profile. Novel biological therapies blocking CGRP transmission are effective and better tolerated, but they are expensive and may not influence brain dysfunctions upstream in the pathophysiological cascade of migraine, ... Read more >>

Expert Rev Neurother (Expert review of neurotherapeutics)
[2020, 20(3):295-302]

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A Randomized Trial to Evaluate OnabotulinumtoxinA for Prevention of Headaches in Adolescents With Chronic Migraine.

Paul K Winner, Marielle Kabbouche, Marcy Yonker, Veronica Wangsadipura, Arlene Lum, Mitchell F Brin,

OBJECTIVE:As a post-approval commitment, this dose-ranging study was undertaken to evaluate efficacy and safety of onabotulinumtoxinA in adolescents. BACKGROUND:In adolescents, migraine is often undiagnosed or misdiagnosed and can present unique management challenges. OnabotulinumtoxinA was approved for prevention of chronic migraine (CM) in adults in 2010. METHODS:This multicenter, double-blind, parallel-group, randomized ... Read more >>

Headache (Headache)
[2020, 60(3):564-575]

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Health-Related Quality of Life in Non-Concussed Children: A Normative Study to Inform Concussion Management.

M Paniccia, C Ippolito, S McFarland, J Murphy, N Reed,

Purpose: There has been a shift to consider pediatric concussion recovery beyond symptom management by considering how health-related quality of life (HRQoL) affects recovery. This study investigated normative ranges of HRQoL in children and explored its relationship with common pediatric concussion variables.Methods: A cross-sectional study of 1,722 non-concussed children 8-12 years ... Read more >>

Dev Neurorehabil (Developmental neurorehabilitation)
[2020, :1-8]

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Internalizing Symptoms in Pediatric Migraine: A Systematic Review Protocol.

Katherine Falla, Paul Ronksley, Melanie Noel, Serena L Orr,

OBJECTIVES:The primary objective of the proposed systematic review is to determine if there is an association between internalizing disorders and symptoms (ie, subclinical symptoms) and migraine in children and adolescents. METHODS:We will perform a peer-reviewed Peer Review of Electronic Search Strategies search of MEDLINE, Embase, PsycINFO, and CINAHL from inception ... Read more >>

Headache (Headache)
[2020, 60(4):761-770]

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Prevalence, burden, and clinical management of migraine in China, Japan, and South Korea: a comprehensive review of the literature.

Takao Takeshima, Qi Wan, Yanlei Zhang, Mika Komori, Serina Stretton, Narayan Rajan, Tamas Treuer, Kaname Ueda,

BACKGROUND:The objective of this review was to determine the unmet needs for migraine in East Asian adults and children. METHODS:We searched MEDLINE and EMBASE (January 1, 1988 to January 14, 2019). Studies reporting the prevalence, humanistic and economic burden, and clinical management of migraine in China (including Hong Kong and ... Read more >>

J Headache Pain (The journal of headache and pain)
[2019, 20(1):111]

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Neurological Etiologies and Pathophysiology of Cyclic Vomiting Syndrome.

Gary N McAbee, Anne Marie Morse, Ward Cook, Vivian Tang, Yuri Brosgol,

Cyclic vomiting syndrome is an idiopathic chronic periodic disorder of childhood which may persist into the adult years. Although cyclic vomiting syndrome is considered a central nervous system disorder, it is often managed by a pediatric gastroenterologist. The practitioner should not assume a gastrointestinal or non-neurological cause of symptoms especially ... Read more >>

Pediatr. Neurol. (Pediatric neurology)
[2019, :]

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