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Magnetic Resonance Imaging in Acute Stroke

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Increased thalamocortical connectivity from the affected thalamus to the unaffected hemisphere in a stroke patient.

Sung Ho Jang, You Sung Seo, Sung Jun Lee,

Neural Regen Res (Neural regeneration research)
[2020, 15(8):1568]

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Apigenin-7-O-β-d-(6″-p-coumaroyl)-glucopyranoside reduces myocardial ischaemia/reperfusion injury in an experimental model via regulating the inflammation response.

Wei Quan, Shanbo Ma, Yanrong Zhu, Qing Shao, Jixing Hou, Xiaoqiang Li,

Context: Traditionally, Clematis tangutica Korsh. (Ranunculaceae) is used as a Tibetan herb for treating indigestion and blood stasis in China. Recently, a flavonoid glycoside, apigenin-7-O-β-d-(6″-p-coumaroyl)-glucopyranoside (APG), was isolated from the whole plant of C. tangutica.Objective: To investigate the cardioprotective effects of APG against myocardial ischaemia/reperfusion injury (MI/RI) and the possible ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2020, 58(1):80-88]

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Recovery of injured corticoreticulospinal tract following cranioplasty in an ischemic stroke patient: a diffusion tensor tractography study.

Sung Ho Jang, Han Do Lee,

Neural Regen Res (Neural regeneration research)
[2020, 15(7):1368]

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Remote ischemic conditioning approach for the treatment of ischemic stroke.

Seyed Mohammad Seyedsaadat, David F Kallmes, Waleed Brinjikji,

Neural Regen Res (Neural regeneration research)
[2020, 15(6):1033-1034]

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Brain activation induced by different strengths of hand grasp: a functional magnetic resonance imaging study.

Hyeok Gyu Kwon, Ju Sang Kim, Mi Young Lee,

Mirror neuron system can be activated by observation and execution of an action. It has an important function of action understanding. We investigated brain activations in humans by observing the strength of a hand grasp using functional magnetic resonance imaging. Twenty right-handed healthy individuals, consisting of 10 males and 10 ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(5):875-879]

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Interhemispheric Functional Connectivity in the Primary Motor Cortex Assessed by Resting-State Functional Magnetic Resonance Imaging Aids Long-Term Recovery Prediction among Subacute Stroke Patients with Severe Hand Weakness.

Yu-Sun Min, Jang Woo Park, Eunhee Park, Ae-Ryoung Kim, Hyunsil Cha, Dae-Won Gwak, Seung-Hwan Jung, Yongmin Chang, Tae-Du Jung,

This study aimed to evaluate the usefulness of interhemispheric functional connectivity (FC) as a predictor of motor recovery in severe hand impairment and to determine the cutoff FC level as a clinically useful parameter. Patients with stroke (n = 22; age, 59.9 ± 13.7 years) who presented with unilateral severe ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(4):]

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A Helpful Tool in Diagnosing Stroke Mimics: Arterial Spin Labeled Perfusion Magnetic Resonance Imaging.

Michael U Antonucci, Milad Yazdani,

BACKGROUND:Prompt and effective management of acute ischemic stroke in the emergency setting requires a high level of suspicion and accurate diagnosis. Conversely, identifying stroke mimics can be challenging, given the similarity of their clinical symptomatology, the necessary rapid assessment and triage, and the overall frenetic pace inherent in the goal ... Read more >>

J Emerg Med (The Journal of emergency medicine)
[2020, :]

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Site and size of lesion predict post-stroke spasticity: A retrospective magnetic resonance imaging study.

Songjin Ri, Anatol Kivi, Peter P Urban, Thomas Wolf, Jörg Wissel,

OBJECTIVE:Clinical parameters for prediction of post-stroke spasticity are well established. This report introduces 2 brain magnetic resonance imaging (MRI) parameters (infarct volume and topographic distribution) as post-stroke spasticity predictors. METHODS:Topographic and volumetric data from brain MRI for 98 patients with ischaemic stroke with spasticity, prevalent within the first 5 days ... Read more >>

J Rehabil Med (Journal of rehabilitation medicine)
[2020, :]

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Atrial Fibrillation and Cognitive Impairment: An Associated Burden or Burden by Association?

Theodora A Manolis, Antonis A Manolis, Evdoxia J Apostolopoulos, Helen Melita, Antonis S Manolis,

Growing evidence suggests that atrial fibrillation (AF), in addition to its thromboembolic risk, is a risk factor for cognitive impairment (CI) via several pathways and mechanisms, further contributing to morbidity/mortality. Prior stroke is a contributor to CI, but AF is also associated with CI independently from prior stroke. Silent brain ... Read more >>

Angiology (Angiology)
[2020, :3319720910669]

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Randomised comparison of a balloon-expandable and self-expandable valve with quantitative assessment of aortic regurgitation using magnetic resonance imaging.

N H M Kooistra, M Abawi, M Voskuil, K Urgel, M Samim, F Nijhoff, H M Nathoe, P A F M Doevendans, S A J Chamuleau, G E H Leenders, T Leiner, A C Abrahams, H B van der Worp, P Agostoni, P R Stella,

INTRODUCTION:Transcatheter aortic valve implantation (TAVI) is a safe and effective treatment for inoperable, intermediate- or high-risk patients with severe symptomatic aortic stenosis and has been associated with excellent clinical outcomes. A clinically relevant remaining problem is aortic regurgitation (AR) post-TAVI, which is associated with increased mortality. Therefore, we conducted a prospective randomised trial ... Read more >>

Neth Heart J (Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation)
[2020, :]

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Mechanical Thrombectomy Using a Stent Retriever with an Intermediate Catheter for Partially Occluded Middle Cerebral-artery Fenestration.

Geng Liao, Zhenyu Zhang, Xiujuan Che, Hanxiang Liang,

BACKGROUND:Middle cerebral artery fenestration (MCAF) is a rare vascular variant of the middle cerebral artery (MCA). When this occlusion occurs, it presents challenges to identification and recanalization. In this paper, we describe a patient with a partially occluded MCAF who was successfully recanalized via mechanical thrombectomy (MT) using a stent ... Read more >>

World Neurosurg (World neurosurgery)
[2020, :]

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The Medial Pontine Mid-Tegmentum Syndrome.

Lara C Wadi, Michael J Kim, Mark J Fisher,

Isolated pontine infarcts are common and are often associated with well-described syndromes that are classified based on their specific clinical presentation and arterial stroke territories. Here we present a case of acute combined diplopia and unilateral lower extremity sensory abnormality. Diffusion-weighted magnetic resonance imaging revealed a punctate area of acute ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2020, :104750]

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Giant “heart appearance-like sign” on MRI in bilateral ponto-medullary junction infraction: case report.

Zhi-Hua Zhou, Yun-Fan Wu, Wei-Feng Wu, Ai-Qun Liu, Qing-Yun Yu, Zhong-Xing Peng, Ming-Fan Hong,

BackgroundBilateral medial medullary infarction (MMI) is uncommon and bilateral medial pons infarction (MPI) is even rarer. “Heart appearance” on magnetic resonance imaging (MRI) is a characteristic presentation of bilateral medial medullary infarction (MMI).Case presentationWe present 67-year-old Chinese diabetic and hypertensive female patient affected with “heart appearance-like” infarction in bilateral ponto-medullary ... Read more >>

BMC Neurol (BMC neurology)
[2020, 20:]

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Early Diffusion Magnetic Resonance Imaging Changes in Normal-Appearing Brain in Pediatric Moyamoya Disease.

Jennifer L Quon, Lily H Kim, Sarah J MacEachern, Maryam Maleki, Gary K Steinberg, Venkatesh Madhugiri, Michael S B Edwards, Gerald A Grant, Kristen W Yeom, Nils D Forkert,

BACKGROUND:Moyamoya disease often leads to ischemic strokes visible on diffusion-weighted imaging (DWI) and T2-weighted magnetic resonance imaging (MRI) with subsequent cognitive impairment. In adults with moyamoya, apparent diffusion coefficient (ADC) is correlated with regions of steal phenomenon and executive dysfunction prior to white matter changes. OBJECTIVE:To investigate quantitative global diffusion ... Read more >>

Neurosurgery (Neurosurgery)
[2020, 86(4):530-537]

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A unique temporary collateral pathway between carotid-vertebrobasilar arteries in a carotid dissection patient.

Xiaogang Liu, Bing Li, Ying Liu, Hongliang Wu, Huilong Zhang, Lianwei Dou, Chuanyu Liu,

BACKGROUND:In adults, the anastomosis between carotid and vertebrobasilar arteries is usually the posterior communicating artery, sometimes the primitive trigeminal artery. In this case, the basilar artery fed the internal carotid artery through the pontine-to-tentorial artery anastomosis after severe stenosis from traumatic carotid dissection. CASE PRESENTATION:A 32-year-old female was diagnosed with ... Read more >>

BMC Neurol (BMC neurology)
[2020, 20(1):97]

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High-resolution compressed-sensing time-of-flight MRA in a case of acute ICA/MCA dissection.

Theo Demerath, Leo Bonati, Amgad El Mekabaty, Tilman Schubert,

PURPOSE:Acute, isolated intracranial dissection (ICD) represents a rare and challenging cause of acute stroke. DSA is considered to be the gold standard imaging modality in patients with ICD. The role of novel, high-resolution (HR) compressed-sensing (CS) time-of-flight (TOF) MRA techniques in ICDs is unclear. METHODS:A 22-year-old male patient with an ... Read more >>

Neuroradiology (Neuroradiology)
[2020, :]

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Cardiac magnetic resonance for asymptomatic patients with type 2 diabetes and cardiovascular high risk (CATCH): a pilot study.

Ming-Yen Ng, Wenli Zhou, Varut Vardhanabhuti, Chi-Ho Lee, Esther Yee Tak Yu, Eric Yuk Fai Wan, Kit Chan, Andrew T Yan, Tai-Pang Ip, Kai-Hang Yiu, Bernd J Wintersperger,

BACKGROUND:Stress cardiovascular magnetic resonance (CMR) to screen for silent myocardial ischaemia in asymptomatic high risk patients with type 2 diabetes mellitus (DM) has never been performed, and its effectiveness is unknown. Our aim was to determine the feasibility of a screening programme using stress CMR by obtaining preliminary data on ... Read more >>

Cardiovasc Diabetol (Cardiovascular diabetology)
[2020, 19(1):42]

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Using novel magnetic resonance imaging methods to predict stroke risk in individuals with sickle cell anemia.

Lori C Jordan, Adetola A Kassim, Karina L Wilkerson, Chelsea A Lee, Spencer L Waddle, Manus J Donahue,

Sickle cell anemia (SCA) is a well-characterized monogenetic disorder with a high prevalence of cerebral vasculopathy, silent cerebral infarcts, and strokes. A significant mechanism for cerebral infarction in SCA is hemodynamic imbalance. To compensate for reduced oxygen-carrying capacity due to anemia, individuals with SCA have chronically elevated cerebral blood flow ... Read more >>

Hematol Oncol Stem Cell Ther (Hematology/oncology and stem cell therapy)
[2020, :]

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White Matter Integrity in Tanzanian Children With Sickle Cell Anemia: A Diffusion Tensor Imaging Study.

Mboka Jacob, Hanne Stotesbury, Jamie M Kawadler, Winok Lapadaire, Dawn E Saunders, Raphael Z Sangeda, Clara Chamba, Ramadhan Kazema, Julie Makani, Fenella J Kirkham, Chris A Clark,

Background and Purpose- Widespread reductions in white matter integrity are associated with cognitive dysfunction in sickle cell anemia. Silent cerebral infarction (SCI), vasculopathy (VSC), and low hemoglobin concentration (Hb) are implicated; we aimed to determine independent contributions to microstructural white matter injury and whether white matter integrity differs across arterial ... Read more >>

Stroke (Stroke)
[2020, 51(4):1166-1173]

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Effect of In-Hospital Remote Ischemic Perconditioning on Brain Infarction Growth and Clinical Outcomes in Patients With Acute Ischemic Stroke: The RESCUE BRAIN Randomized Clinical Trial.

Fernando Pico, Bertrand Lapergue, Marc Ferrigno, Charlotte Rosso, Elena Meseguer, Marie-Laure Chadenat, Frederic Bourdain, Michael Obadia, Catherine Hirel, Duc Long Duong, Sandrine Deltour, Philippe Aegerter, Julien Labreuche, Amina Cattenoy, Didier Smadja, Hassan Hosseini, Benoit Guillon, Valérie Wolff, Yves Samson, Charlotte Cordonnier, Pierre Amarenco,

Importance:Treatment with remote ischemic perconditioning has been reported to reduce brain infarction volume in animal models of stroke. Whether this neuroprotective effect was observed in patients with acute ischemic stroke remains unknown. Objective:To determine whether treatment with remote ischemic perconditioning administered to the leg of patients with acute ischemic stroke ... Read more >>

JAMA Neurol (JAMA neurology)
[2020, :]

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Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study.

Kamini Rakkar, Othman Othman, Nikola Sprigg, Philip Bath, Ulvi Bayraktutan,

Ischemic stroke is a devastating, life altering event which can severely reduce patient quality of life. Despite years of research there have been minimal therapeutic advances. Endothelial progenitor cells (EPCs), stem cells involved in both vasculogenesis and angiogenesis, may be a potential therapeutic target. After a stroke, EPCs migrate to ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(7):1300-1307]

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Multimodal treatment for spinal cord injury: a sword of neuroregeneration upon neuromodulation.

Ya Zheng, Ye-Ran Mao, Ti-Fei Yuan, Dong-Sheng Xu, Li-Ming Cheng,

Spinal cord injury is linked to the interruption of neural pathways, which results in irreversible neural dysfunction. Neural repair and neuroregeneration are critical goals and issues for rehabilitation in spinal cord injury, which require neural stem cell repair and multimodal neuromodulation techniques involving personalized rehabilitation strategies. Besides the involvement of ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(8):1437-1450]

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Magnetic resonance imaging markers reflect cognitive outcome after rehabilitation in children with acquired brain injury.

Volker Ressel, Daphne Berati, Carla Raselli, Karin Birrer, Raimund Kottke, Hubertus Ja van Hedel, Ruth O'Gorman Tuura,

PURPOSE:To test markers from conventional and diffusion Magnetic Resonance Imaging (MRI) as possible predictors of cognitive outcome following rehabilitation therapy in children with acquired brain injury (ABI). METHODS:Twenty-one children (10 boys, mean age 11.6 years, range 7.1-19.4) with stroke or traumatic brain injury underwent MRI including Diffusion Tensor Imaging (DTI) ... Read more >>

Eur J Radiol (European journal of radiology)
[2020, 126:108963]

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Proportion of acute ischaemic strokes attributable to a cardiac aetiology in an unselected young patient population: A single centre experience.

Rahul Bahl, Magdalena Kubiak, Syarah Yusoff, Hsiu Tung, James Stirrup, André van Wyk, Kiruba Nagaratnam, Neil Ruparelia,

The incidence of acute ischaemic stroke in young patients is increasing and identifying the underlying cause is critically important with regards to their optimal management. The true proportion of cardiac causes of stroke in young patients is poorly defined. We aimed to determine the proportion of strokes attributable to cardiac ... Read more >>

Clin Med (Lond) (Clinical medicine (London, England))
[2020, 20(2):174-177]

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Effect of brain lesions on voluntary cough in patients with supratentorial stroke: an observational study

Sun Im, Kyoung Lee, Seong Lim, Geun-Young Park,

<title>Abstract</title> <p> Background: Patients with stroke are known to manifest decreased cough force, which may increase the risk of aspiration. Specific brain lesions have been linked to impaired reflexive cough. However, only a few studies investigated whether specific stroke lesions are associated with impaired voluntary cough. The present ... Read more >>

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