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Dynein and MEL-28 contribute in parallel to oogenic maturity in C. elegans.

Jay Gandhi, Giulia Crosio, Anita G Fernandez,

<i>dhc-1(or283ts); mel-28(t1684)</i> double mutants have a severely reduced brood size compared to the wild-type and compared to each single mutant. To determine if this low-fecundity phenotype is associated with oocyte maturity defects, we used markers to assess the maturity of oocytes in the proximal gonad. We studied phosphorylated histone H3, ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Diffusion tensor imaging of the hippocampus reflects the severity of hippocampal injury induced by global cerebral ischemia/reperfusion injury.

Wen-Zhu Wang, Xu Liu, Zheng-Yi Yang, Yi-Zheng Wang, Hai-Tao Lu,

At present, predicting the severity of brain injury caused by global cerebral ischemia/reperfusion injury (GCI/RI) is a clinical problem. After such an injury, clinical indicators that can directly reflect neurological dysfunction are lacking. The change in hippocampal microstructure is the key to memory formation and consolidation. Diffusion tensor imaging is ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):838-844]

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Assessment of structural brain changes in patients with type 2 diabetes mellitus using the MRI-based brain atrophy and lesion index.

Heng Zhao, Fang Wang, Guang-Hua Luo, Hao Lei, Fei Peng, Qiu-Ping Ren, Wei Chen, Yan-Fang Wu, Li-Chun Yin, Jin-Cai Liu, Shi-Nong Pan,

Patients with type 2 diabetes mellitus (T2DM) often have cognitive impairment and structural brain abnormalities. The magnetic resonance imaging (MRI)-based brain atrophy and lesion index can be used to evaluate common brain changes and their correlation with cognitive function, and can therefore also be used to reflect whole-brain structural changes ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(3):618-624]

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Brain functional remodeling caused by sciatic nerve transposition repair in rats identified by multiple-model resting-state blood oxygenation level-dependent functional magnetic resonance imaging analysis.

Yu-Song Yuan, Hai-Lin Xu, Zhong-Di Liu, Yu-Hui Kou, Bo Jin, Pei-Xun Zhang,

Lower extremity nerve transposition repair has become an important treatment strategy for peripheral nerve injury; however, brain changes caused by this surgical procedure remain unclear. In this study, the distal stump of the right sciatic nerve in a rat model of sciatic nerve injury was connected to the proximal end ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(2):418-426]

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Reference biometry of foetal brain by prenatal MRI and the distribution of measurements in foetuses with ventricular septal defect.

Feng Xia, Yu Guo, Hua He, Peiwen Chen, Jianbo Shao, Wei Xia,

<h4>Objective</h4>To provide the reference biometric measurements of the normal foetal brain by prenatal MRI and describe the distribution of measurements in the foetuses with ventricular septal defect (VSD).<h4>Methods</h4>This retrospective study analysed the biometric measurements of 218 foetuses between 18 - 37 gestational weeks with normal MRI findings from July 2014 to August ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1428-1437]

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Long-term neurodevelopment outcomes of hand, foot and mouth disease inpatients infected with EV-A71 or CV-A16, a retrospective cohort study.

Lu Liang, Yibing Cheng, Yu Li, Qing Shang, Jiao Huang, Caiyun Ma, Shuanfeng Fang, Lu Long, Chongchen Zhou, Zhiping Chen, Peng Cui, Nan Lv, Pu Lou, Yajie Cui, Saraswathy Sabanathan, H Rogier van Doorn, Rongsheng Luan, Lance Turtle, Hongjie Yu,

Hand, foot and mouth disease (HFMD) is a common infectious disease in western Asia area and the full range of the long-term sequelae of HFMD remains poorly described. We conducted a retrospective hospital-based cohort study of HFMD patients with central nervous system (CNS) complications caused by EV-A71 or CV-A16 between ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):545-554]

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Long-term preservation of pharyngeal swallowing function in MM2-cortical-type sporadic Creutzfeldt-Jakob disease.

Yuichi Hayashi, Kenjiro Kunieda, Takuya Kudo, Akio Kimura, Ichiro Fujishima, Takayoshi Shimohata,

Swallowing function in long-term survivors of Creutzfeldt-Jakob disease (CJD) has not been elucidated. Herein, we report a patient with MM2-cortical-type sporadic CJD (MM2C-type sCJD) with long-term preservation of pharyngeal swallowing function using videofluoroscopic (VF) examination of swallowing. A 55-year-old woman was admitted to hospital because of dyscalculia and memory disturbance ... Read more >>

Prion (Prion)
[2021, 15(1):82-86]

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The Diagnostic Value of Magnetic Resonance Imaging in Posttraumatic Trigeminal Neuropathic Pain.

Frederik Peeters, Fréderic Van der Cruyssen, Jan W Casselman, Robert Hermans, Tara Renton, Reinhilde Jacobs, Constantinus Politis,

<h4>Aims</h4>To evaluate the diagnostic value of non-nerve-selective MRI sequences in posttraumatic trigeminal neuropathic pain (PTNP).<h4>Methods</h4>This study retrospectively analyzed all MRI protocols performed between February 2, 2012 and June 20, 2018 commissioned by the Department of Oral and Maxillofacial Surgery, University Hospitals Leuven. Demographic, clinical, and radiologic data were extracted from ... Read more >>

J Oral Facial Pain Headache (Journal of oral & facial pain and headache)
[2021, 35(1):35-40]

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Stroke mimics: incidence, aetiology, clinical features and treatment.

Brian H Buck, Naveed Akhtar, Anas Alrohimi, Khurshid Khan, Ashfaq Shuaib,

Mimics account for almost half of hospital admissions for suspected stroke. Stroke mimics may present as a functional (conversion) disorder or may be part of the symptomatology of a neurological or medical disorder. While many underlying conditions can be recognized rapidly by careful assessment, a significant proportion of patients unfortunately ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):420-436]

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Analysis of the influencing factors related to liver and cardiac iron overload in MDS patients detected by MRI in the real world.

Chao Xiao, Yao Zhang, Jun-Gong Zhao, Lu-Xi Song, You-Shan Zhao, Yan Jia, Juan Guo, Shuang Han, Zhao-Wei Li, Cha Guo, Xiao Li, Chun-Kang Chang,

<h4>Objectives</h4>We aim to explore and analyze the related influencing factors of liver and cardiac iron overload in MDS patients detected by magnetic resonance imaging (MRI).<h4>Methods</h4>We have detected cardiac T2* and liver T2* by MRI in 105 MDS patients. Among them, 20 patients accepted MRI examination before and after iron chelation ... Read more >>

Hematology (Hematology (Amsterdam, Netherlands))
[2021, 26(1):123-133]

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Characteristics of 18F-FDG and 18F-FDOPA PET in an 8-year-old neutered male Yorkshire Terrier dog with glioma: long-term chemotherapy using hydroxyurea plus imatinib with prednisolone and immunoreactivity for PDGFR-β and LAT1.

Taesik Yun, Yoonhoi Koo, Sanggu Kim, Wonguk Lee, Hakhyun Kim, Dongwoo Chang, Soochong Kim, Mhan-Pyo Yang, Byeong-Teck Kang,

An 8-year-old neutered male Yorkshire Terrier dog presented with head pressing, vestibular ataxia, neck tenderness, and no oculocephalic reflex. A demarcated lesion in the pons was identified on MRI. The patient was tentatively diagnosed with a glioma and was treated with hydroxyurea plus imatinib and prednisolone. After 30 days of ... Read more >>

Vet Q (The veterinary quarterly)
[2021, 41(1):163-171]

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Genetic Creutzfeldt-Jakob disease shows fatal family insomnia phenotype.

Bin Chen, Shan Zhang, Ying Xiao, Yingman Wu, Weiting Tang, Limin Yan, Zhengxue Zhang, Shengquan Qin, Mingming Dai, Yong You,

We report a case of genetic Creutzfeldt-Jakob disease (gCJD), which has a clinical phenotype that is highly similar to Fatal Family Insomnia (FFI) and has a triad of Wernicke-Korsakoff syndrome (WKs) at the developmental stage of the disease. The 51-year-old male complained of sleep disorder and imbalance who had visited ... Read more >>

Prion (Prion)
[2021, 15(1):177-182]

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Imaging of Prostate Cancer.

Heinz-Peter Schlemmer, Bernd Joachim Krause, Viktoria Schütz, David Bonekamp, Sarah Schwarzenböck, Markus Hohenfellner,

<h4>Background</h4>Prostate cancer is the most common type of solid tumor in men and the second most common cause of cancer-related death in males in Germany. The conventional strategy for its primary detection, i.e., systematic ultrasound-guided prostate biopsy in men who have elevated PSA levels and/or positive findings on digital rectal ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Is there still a role for digital rectal examination in the prostate cancer diagnostic pathway in the COVID-19 and post COVID-19 era?

Wei Shen Tan, Anton Wong, Wasim Mahmalji, Asif Raza,

Digital rectal examination (DRE) is routinely performed as part of a urology clinical assessment in patients with a clinical suspicion of prostate cancer. An abnormal DRE or a raised prostate specific antigen (PSA) level are part of the criteria for primary care referral to secondary care due to a suspicion ... Read more >>

Aging Male (The aging male : the official journal of the International Society for the Study of the Aging Male)
[2021, 24(1):92-94]

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Secondary spinal cord changes and spinal deformity following traumatic spinal cord injury.

Mohammad Ahmad Jamous, Raed Awni Jaradat, Mustafa Mohamed Alwani,

Secondary spinal cord changes can follow spinal cord injuries (SCIs). This retrospective study was to uncover the chronic secondary changes that affect the spinal cord following severe injuries and to evaluate the influence of residual spinal deformity in the development of posttraumatic spinal cord changes. Fifty-eight patients (39 male, 19 ... Read more >>

Aging Male (The aging male : the official journal of the International Society for the Study of the Aging Male)
[2021, 24(1):95-100]

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The efficiency of prostate-specific antigen density measurement using three different methods on the prediction of biochemical recurrence.

Yavuz Onur Danacioglu, Ferhat Keser, Özgür Efiloğlu, Meftun Culpan, Salih Polat, Ramazan Gokhan Atis, Asif Yildirim,

<h4>Background</h4>The aim of this study was to evaluate the efficiency of prostate-specific antigen (PSA) density (PSAD) calculated through prostate volume (PV) obtained <i>via</i> transrectal ultrasound (TRUS) and magnetic resonance imaging (MRI) and actual prostate weight (PW) methods obtained <i>via</i> pathological evaluation on the prediction of biochemical recurrence (BCR) in the ... Read more >>

Aging Male (The aging male : the official journal of the International Society for the Study of the Aging Male)
[2021, 24(1):15-23]

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Feasibility of Magnetic Resonance Angiography in Patients With Legg-Calvé-Perthes Disease.

Patricia Moreno Grangeiro, João C Rodrigues, Luiz R A de Angeli, Hilton Leão Filho, Nei B Montenegro, Roberto Guarniero, Molly Dempsey, Harry K W Kim,

<h4>Background</h4>The etiology of Legg-Calvé-Perthes disease (LCPD) remains unknown; however, interruption of medial circumflex femoral artery (MCFA) supply to the femoral head is the key pathogenic factor. The main purpose of this study is to determine the feasibility of using magnetic resonance angiography (MRA) to evaluate the course of the MCFA ... Read more >>

J Pediatr Orthop (Journal of pediatric orthopedics)
[2021, 41(9):e774-e779]

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A Chinese patient with the clinical features of Parkinson's disease contains a single copy of octarepeat deletion in PRNP case report.

Qi Shi, Xiao-Jing Shen, Li-Ping Gao, Kang Xiao, Wei Zhou, Yuan Wang, Cao Chen, Xiao-Ping Dong,

Insertion or deletion of single copy of octapeptide repeat (OR) in human PrP protein are considered as polymorphism, while of insertions of more numbers of OR and deletion of two copies of OR are associated with genetic prion diseases.Here, we reported a 58-year-old female patient who displayed clinical manifestations of ... Read more >>

Prion (Prion)
[2021, 15(1):121-125]

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Reliability and Validity of Visual Estimation of Femoral Head Hypoperfusion on Perfusion MRI in Legg-Calve-Perthes Disease.

David Y Chong, Tim Schrader, Jennifer C Laine, Scott Yang, Shawn R Gilbert, Harry K W Kim, ,

<h4>Background</h4>Assessing the severity of Legg-Calve-Perthes disease is important for treatment decision-making and determining prognosis. Perfusion magnetic resonance imaging (MRI) scans have improved our ability to assess femoral head hypoperfusion, and the use of an image analysis software called HipVasc (Scottish Rite for Children, Dallas TX) has allowed precise quantification for ... Read more >>

J Pediatr Orthop (Journal of pediatric orthopedics)
[2021, 41(9):e780-e786]

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Quantitative diffusion MRI of the abdomen and pelvis.

Diego Hernando, Yuxin Zhang, Ali Pirasteh,

Diffusion MRI has enormous potential and utility in the evaluation of various abdominal and pelvic disease processes, including cancer and non-cancer imaging of the liver, prostate, and other organs. Quantitative diffusion MRI is based on acquisitions with multiple diffusion encodings followed by quantitative mapping of diffusion parameters that are sensitive ... Read more >>

Med Phys (Medical physics)
[2021, :]

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Comparison of bone SPECT/CT and MRI in detection of pain generator in ankle and foot pain: a retrospective diagnostic study.

Kanhaiyalal Agrawal, Shakti Swaroop, P Sai Sradha Patro, Sujit Kumar Tripathy, Suprava Naik, Sandeep Velagada,

<h4>Objective</h4>To study the sensitivity and specificity of MRI and bone SPECT-CT in detecting the pain generator in ankle and foot pain with diagnostic dilemma.<h4>Methods</h4>Retrospectively data of patients with ankle or foot pain who underwent both MRI and Bone SPECT-CT were analyzed. The lesions and probable pain generator sites were reported ... Read more >>

Nucl Med Commun (Nuclear medicine communications)
[2021, 42(10):1085-1096]

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Spontaneous ilio-psoas haematomas (IPHs): a warning for COVID-19 inpatients.

Alessandra Vergori, Elisa Pianura, Patrizia Lorenzini, Alessandra D'Abramo, Federica Di Stefano, Susanna Grisetti, Serena Vita, Carmela Pinnetti, Davide Roberto Donno, Maria Cristina Marini, Emanuele Nicastri, Stefania Ianniello, Andrea Antinori, ,

<h4>Introduction</h4>Critically ill patients with COVID-19 are at increased risk of developing a hypercoagulable state due to haemostatic changes directly related to the SARS-CoV-2 infection or to the consequence of the cytokine storm. Anticoagulation is now recommended to reduce the thrombotic risk. Ilio-psoas haematoma (IPH) is a potentially lethal condition that ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):295-301]

Cited: 5 times

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Chiari III Malformation on Prenatal and Postnatal Imaging Complicated by Syndrome of Inappropriate Secretion of Anti-diuretic Hormone (SIADH) and Serratia marcescens Meningitis

Ryan McGeary, Chetan Shah,

Among various types of Chiari malformations (CMs), CM III is the most infrequently encountered. In this article, we present a case of CM III with occipital cephalocele appreciated on both prenatal imaging and postnatal follow-up MRI. This case illustrates not only the evolution of this malformation from the in-utero images ... Read more >>

Cureus (Cureus)
[0, 13(8):]

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Radiomic Features on Multiparametric MRI for Preoperative Evaluation of Pituitary Macroadenomas Consistency: Preliminary Findings.

Tao Wan, Chunxue Wu, Ming Meng, Tao Liu, Chuzhong Li, Jun Ma, Zengchang Qin,

<h4>Background</h4>Preoperative assessment of the consistency of pituitary macroadenomas (PMA) might be needed for surgical planning.<h4>Purpose</h4>To investigate the diagnostic performance of radiomics models based on multiparametric magnetic resonance imaging (mpMRI) for preoperatively evaluating the tumor consistency of PMA.<h4>Study type</h4>Retrospective.<h4>Population</h4>One hundred and fifty-six PMA patients (soft consistency, N = 104 vs. hard consistency, N = 52), ... Read more >>

J Magn Reson Imaging (Journal of magnetic resonance imaging : JMRI)
[2021, :]

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General movement assessment is correlated with neonatal behavior neurological assessment/cerebral magnetic resonance imaging in preterm infants

Jinjun Zhou, Shuangshuang Li, Li Gu, Xiaohua Zhang, Zhen Tang,

Abstract To explore the relationship between general movements (GMs) and neonatal behavior neurological assessment (NBNA)/cerebral magnetic resonance imaging (MRI) in preterm infants. Forty preterm infants were examined with GMs assessment before gestational age of 40 weeks; NBNA was performed at the age of 40 weeks; cerebral MRI was performed at the age ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(37):]

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